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Research Outputs

  1. 2019
  2. Exploring the effect of implementation and context on a stepped-wedge randomised controlled trial of a vital sign triage device in routine maternity care in low-resource settings

    Vousden, N., Lawley, E., Seed, P. T., Gidiri, M. F., Charantimath, U., Makonyola, G., Brown, A., Yadeta, L., Best, R., Chinkoyo, S., Vwalika, B., Nakimuli, A., Ditai, J., Greene, G., Chappell, L. C., Sandall, J., Shennan, A. H., Bukani, D., Toussaint, P., Vixama, A. & 30 others, Hill, C., Nakirijja, E., Birungi, D., Kalyowa, N., Namakuli, D., Byamugisha, J., Odeke, N. M., Wandabwa, J., Momodou, F., Sesay, M., Sandi, P., Conteh, J., Kamara, J., Clarke, M., Miti, J., Chima, M., Kopeka, M., Jere, C., Musonda, T., Mambo, V., Guchale, Y., Surur, F., Mungarwadi, G. M., Mastiholi, S. S., Karadiguddi, C. C., Hezelgrave, N., Duhig, K. E., Kachinjika, M., Bellad, M. & Makwakwa, J., 18 Apr 2019, In : Implementation Science. 14, 1, 38.

    Research output: Contribution to journalArticle

  3. Incidence of eclampsia and related complications across 10 low- and middle-resource geographical regions: Secondary analysis of a cluster randomised controlled trial

    CRADLE Trial Collaborative Group, 29 Mar 2019, In : PLoS Medicine. 16, 3, 15 p., e1002775.

    Research output: Contribution to journalArticle

  4. Knowledge Gaps and Emerging Research Areas in Intrauterine Growth Restriction-Associated Brain Injury

    Fleiss, B., Wong, F., Brownfoot, F., Shearer, I. K., Baud, O., Walker, D. W., Gressens, P. & Tolcos, M., 29 Mar 2019, In : Frontiers in Endocrinology . 10, MAR, 188.

    Research output: Contribution to journalReview article

  5. Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses

    Ovadia, C., Seed, P. T., Sklavounos, A., Geenes, V., Di Illio, C., Chambers, J., Kohari, K., Bacq, Y., Bozkurt, N., Brun-furrer, R., Bull, L., Estiú, M. C., Grymowicz, M., Gunaydin, B., Hague, W. M., Haslinger, C., Hu, Y., Kawakita, T., Kebapcilar, A. G., Kebapcilar, L. & 20 others, Kondrackienė, J., Koster, M. P. H., Kowalska-kańka, A., Kupčinskas, L., Lee, R. H., Locatelli, A., Macias, R. I. R., Marschall, H., Oudijk, M. A., Raz, Y., Rimon, E., Shan, D., Shao, Y., Tribe, R., Tripodi, V., Yayla Abide, C., Yenidede, I., Thornton, J. G., Chappell, L. C. & Williamson, C., 2 Mar 2019, In : The Lancet. 393, 10174, p. 899-909 11 p.

    Research output: Contribution to journalArticle

  6. Application of hepatic cytochrome b5/P450 reductase null (HBRN) mice to study the role of cytochrome b5 in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine

    Reed, L., Indra, R., Mrizova, I., Moserova, M., Schmeiser, H. H., Wolf, C. R., Henderson, C. J., Stiborova, M., Phillips, D. H. & Arlt, V. M., 1 Mar 2019, In : Toxicology and Applied Pharmacology. 366, p. 64-74 11 p.

    Research output: Contribution to journalArticle

  7. Quality of stepped-wedge trial reporting can be reliably assessed using an updated CONSORT: crowd-sourcing systematic review

    The SW-CRT Review Group, Hemming, K., Carroll, K., Thompson, J., Forbes, A., Taljaard, M., Dutton, S. J., Madurasinghe, V., Morgan, K., Stuart, B., Fielding, K., Cornelius, V., Turner, E. L., Hooper, R., Giraudeau, B., Seed, P. T., Nickless, A., Grayling, M., Prague, M., Kerry, S. & 31 others, Bell, L., Watson, E., Gafoor, R., Marlin, N., Yorganci, E., Smith, L., Mbekwe, M., Teerenstra, S., Chan, C., Moerbeek, M., Jacobsen, P., Bond, S., Jones, B., Preisser, J., Kanaan, M., Hewitt, C., Easter, C., Pellatt-Higgins, T., Pankhurst, L., Agbla, S. C., Eldridge, S., Lerner, R. G., Leyrat, C., Pilling, M., Forman, J. R., Bhattacharya, I., Magill, N., Candlish, J., McDowell, C., Martin, J. & Kristunas, C., 1 Mar 2019, In : Journal of Clinical Epidemiology. 107, p. 77-88 12 p.

    Research output: Contribution to journalReview article

  8. Effect of a novel vital sign device on maternal mortality and morbidity in low-resource settings: a pragmatic, stepped-wedge, cluster-randomised controlled trial

    CRADLE Trial Collaborative Group, Vousden, N., Lawley, E., Nathan, H. L., Seed, P. T., Gidiri, M. F., Goudar, S., Sandall, J., Chappell, L. C., Shennan, A. H., Kachinjika, M., Bukani, D., Makwakwa, J., Makonyola, G., Brown, A., Toussaint, P., Vixama, A., Greene, G., Hill, C., Nakiriija, E. & 31 others, Birungi, D., Kalyowa, N., Namakula, D., Byamugisha, J., Nakimuli, A., Mackayi Odeke, N., Ditai, J., Wandabwa, J., Momodou, F., Sesay, M., Sandi, P., Conteh, J., Kamara, J., Clarke, M., Best, R., Miti, J., Kopeka, M., Vwalika, B., Chima, M., Musonda, T., Jere, C., Chinkoyo, S., Mambo, V., Guchale, Y., Yadeta, L., Surur, F., Mungarwadi, G. M., Mastiholi, S. S., Karadiguddi, C. C., Hezelgrave, N. & Duhig, K. E., Mar 2019, In : The Lancet. Global health. 7, 3, p. e347-e356

    Research output: Contribution to journalArticle

  9. Serum creatinine in pregnancy: a systematic review

    Wiles, K., Bramham, K., Seed, P. T., Nelson-Piercy, C., Lightstone, L. & Chappell, L. C., Mar 2019, In : Kidney International Reports. 4, 3, p. 408-419 12 p.

    Research output: Contribution to journalArticle

  10. The potential of omics approaches to elucidate mechanisms of biodiesel-induced pulmonary toxicity

    Selley, L., Phillips, D. H. & Mudway, I., 8 Jan 2019, In : Particle And Fibre Toxicology. 16, 1, p. 4 4.

    Research output: Contribution to journalReview article

  11. Temporal and external validation of the fullPIERS model for the prediction of adverse maternal outcomes in women with pre-eclampsia

    Ukah, U. V., Payne, B., Karjalainen, H., Kortelainen, E., Seed, P. T., Conti-Ramsden, F. I., Cao, V., Laivuori, H., Hutcheon, J., Chappell, L., Ansermino, J. M., Vatish, M., Redman, C., Lee, T., Li, L., Magee, L. A. & von Dadelszen, P., Jan 2019, In : Pregnancy Hypertension. 15, p. 42-50 9 p.

    Research output: Contribution to journalArticle

  12. MAVRIC: A Multicentre Randomised Controlled Trial of Transabdominal Versus Transvaginal Cervical Cerclage

    Shennan, A., Chandiramani, M., Bennett, P., David, A. L., Girling, J., Ridout, A., Seed, P. T., Simpson, N., Thornton, S., Tydeman, G., Quenby, S. & Carter, J., 2019, In : American Journal of Obstetrics and Gynecology.

    Research output: Contribution to journalArticle

  13. 2018
  14. Rationale & design of the PROMISES study: A prospective assessment and validation study of salivary progesterone as a test for preterm birth in pregnant women from rural India

    Sharma, P., Khan, S., Ghule, M., Shivkumar, V. B., Dargan, R., Seed, P. T., Sarkar, A., Mehra, S., Shivkumar, P. V. & Tribe, R. M., 22 Dec 2018, In : Reproductive Health. 15, 1, 215.

    Research output: Contribution to journalArticle

  15. Congenital cytomegalovirus infection alters olfaction prior to hearing deterioration in mice

    Lazarini, F., Katsimpardi, L., Levivien, S., Wagner, S., Gressens, P., Teissier, N. & Lledo, P-M., 5 Dec 2018, In : Journal of Neuroscience. p. 10424-10437

    Research output: Contribution to journalArticle

  16. Bulky DNA adducts, microRNA profiles, and lipid biomarkers in Norwegian tunnel finishing workers occupationally exposed to diesel exhaust

    Rynning, I., Arlt, V. M., Vrbova, K., Neča, J., Rossner, P., Klema, J., Ulvestad, B., Petersen, E., Skare, Ø., Haugen, A., Phillips, D. H., Machala, M., Topinka, J. & Mollerup, S., 13 Nov 2018, In : Occupational & Environmental Medicine.

    Research output: Contribution to journalArticle

  17. Magnesium sulphate induces preconditioning in preterm rodent models of cerebral hypoxia-ischemia

    Koning, G., Lyngfelt, E., Svedin, P., Leverin, A-L., Jinnai, M., Gressens, P., Thornton, C., Wang, X., Mallard, C. & Hagberg, H., Nov 2018, In : International Journal of Developmental Neuroscience.

    Research output: Contribution to journalArticle

  18. The impact of ethnicity on adverse perinatal outcome in women with chronic hypertension: a cohort study

    Webster, L. M., Bramham, K., Seed, P. T., Homsy, M., Widdows, K., Webb, A. J., Nelson-Piercy, C., Magee, L., Thilaganathan, B., Myers, J. E. & Chappell, L. C., 14 Oct 2018, In : Ultrasound in Obstetrics and Gynecology.

    Research output: Contribution to journalArticle

  19. Myelination induction by a histamine H3 receptor antagonist in a mouse model of preterm white matter injury

    Rangon, C-M., Schang, A-L., Van Steenwinckel, J., Schwendimann, L., Lebon, S., Fu, T., Chen, L., Beneton, V., Journiac, N., Young-Ten, P., Bourgeois, T., Maze, J., Matrot, B., Baburamani, A. A., Supramaniam, V., Mallard, C., Trottet, L., Edwards, A. D., Hagberg, H., Fleiss, B. & 3 others, Li, J., Tshen Chuang, T. & Gressens, P., 12 Sep 2018, In : Brain, Behavior, and Immunity.

    Research output: Contribution to journalArticle

  20. The Cerebrospinal Fluid Inflammatory Response to Preterm Birth

    Boardman, J. P., Ireland, G., Sullivan, G., Pataky, R., Fleiss, B., Gressens, P. & Miron, V., 12 Sep 2018, In : Frontiers in Physiology. 9, p. 1299

    Research output: Contribution to journalArticle

  21. A Slow-Digesting, Low-Glycemic Load Nutritional Beverage Improves Glucose Tolerance in Obese Pregnant Women Without Gestational Diabetes

    Maitland, R., Patel, N., Barr, S., Sherry, C., Marriage, B., Seed, P., Fernandez, L. G., Pedrosa, J. M. L., Murphy, H., Rueda, R. & Poston, L., 11 Sep 2018, In : Diabetes Technology and Therapeutics. 20, 10, p. 672-680 9 p.

    Research output: Contribution to journalArticle

  22. How to reprogram microglia toward beneficial functions

    Fumagalli, M., Lombardi, M., Gressens, P. & Verderio, C., 8 Sep 2018, In : Glia.

    Research output: Contribution to journalReview article

  23. A systems-level framework for drug discovery identifies Csf1R as an anti-epileptic drug target

    Srivastava, P. K., van Eyll, J., Godard, P., Mazzuferi, M., Delahaye-Duriez, A., Steenwinckel, J. V., Gressens, P., Danis, B., Vandenplas, C., Foerch, P., Leclercq, K., Mairet-Coello, G., Cardenas, A., Vanclef, F., Laaniste, L., Niespodziany, I., Keaney, J., Gasser, J., Gillet, G., Shkura, K. & 6 others, Chong, S-A., Behmoaras, J., Kadiu, I., Petretto, E., Kaminski, R. M. & Johnson, M. R., 3 Sep 2018, In : Nature Communications. 9, 1, p. 3561

    Research output: Contribution to journalArticle

  24. Oligodendrocyte precursor survival and differentiation requires chromatin remodeling by Chd7 and Chd8

    Marie, C., Clavairoly, A., Frah, M., Hmidan, H., Yan, J., Zhao, C., Van Steenwinckel, J., Daveau, R., Zalc, B., Hassan, B., Thomas, J-L., Gressens, P., Ravassard, P., Moszer, I., Martin, D. M., Lu, Q. R. & Parras, C., 14 Aug 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 35

    Research output: Contribution to journalArticle

  25. Hepatic DNA damage in harbour porpoises (Phocoena phocoena) stranded along the English and Welsh coastlines

    Acevedo-Whitehouse, K., Cole, K. J., Phillips, D. H., Jepson, P. D., Deaville, R. & Arlt, V. M., Aug 2018, In : Environmental and Molecular Mutagenesis. 59, 7, p. 613-624

    Research output: Contribution to journalArticle

  26. Creating biobanks in low and middle-income countries to improve knowledge: The PREPARE initiative

    De Oliveira, L., Dias, M. A. B., Jeyabalan, A., Payne, B., Redman, C. W., Magee, L., Poston, L., Chappell, L., Seed, P., von Dadelszen, P. & Roberts, J. M., Jul 2018, In : Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health. 13, p. 62-64 3 p.

    Research output: Contribution to journalArticle

  27. Gestational diabetes modifies the association between PlGF in early pregnancy and preeclampsia in women with obesity

    Vieira, M. C., Begum, S., Seed, P. T., Badran, D., Briley, A. L., Gill, C., Godfrey, K. M., Lawlor, D. A., Nelson, S. M., Patel, N., Sattar, N., White, S. L., Poston, L., Pasupathy, D. & UPBEAT Consortium, Jul 2018, In : Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health. 13, p. 267-272

    Research output: Contribution to journalArticle

  28. Dietary omega-3 deficiency exacerbates inflammation and reveals spatial memory deficits in mice exposed to lipopolysaccharide during gestation

    Labrousse, V. F., Leyrolle, Q., Amadieu, C., Aubert, A., Sere, A., Coutureau, E., Grégoire, S., Bretillon, L., Pallet, V., Gressens, P., Joffre, C., Nadjar, A. & Layé, S., 4 Jun 2018, In : Brain, Behavior, and Immunity.

    Research output: Contribution to journalArticle

  29. Interpregnancy weight change and adverse pregnancy outcomes: A systematic review and meta-analysis

    Oteng-Ntim, E., Mononen, S., Sawicki, O., Seed, P. T., Bick, D. & Poston, L., Jun 2018, In : BMJ open. 8, 6, 14 p., e018778.

    Research output: Contribution to journalReview article

  30. Hippocampal Radial Glial Subtypes and Their Neurogenic Potential in Human Fetuses and Healthy and Alzheimer's Disease Adults

    Cipriani, S., Ferrer, I., Aronica, E., Kovacs, G. G., Verney, C., Nardelli, J., Khung, S., Delezoide, A-L., Milenkovic, I., Rasika, S., Manivet, P., Benifla, J-L., Deriot, N., Gressens, P. & Adle-Biassette, H., 2 May 2018, In : Cerebral cortex (New York, N.Y. : 1991).

    Research output: Contribution to journalArticle

  31. A novel method for source-specific hemoglobin adducts of nitro-polycyclic aromatic hydrocarbons

    Wheelock, K., Zhang, J. J., McConnell, R., Tang, D., Volk, H. E., Wang, Y., Herbstman, J. B., Wang, S., Phillips, D. H., Camann, D., Gong, J. & Perera, F., 1 May 2018, In : Environmental Science: Processes and Impacts. 20, 5, p. 780-789 10 p.

    Research output: Contribution to journalArticle

  32. Differentiation-associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic-metabolising activity of "luminal" muscle-invasive bladder cancers

    Baker, S. C., Arlt, V. M., Indra, R., Joel, M., Stiborova, M., Eardley, I., Ahmad, N., Otto, W., Burger, M., Rubenwolf, P., Phillips, D. H. & Southgate, J., May 2018, In : Molecular Carcinogenesis. 57, 5, p. 606-618

    Research output: Contribution to journalArticle

  33. Evaluation of a novel vital sign device to reduce maternal mortality and morbidity in low-resource settings: a mixed method feasibility study for the CRADLE-3 trial

    Vousden, N., Lawley, E., Nathan, H. L., Seed, P. T., Brown, A., Muchengwa, T., Charantimath, U., Bellad, M., Gidiri, M. F., Goudar, S., Chappell, L. C., Sandall, J., Shennan, A. H. & CRADLE Trial Collaborative Group, 27 Apr 2018, In : BMC Pregnancy and Childbirth. 18, 1, 115.

    Research output: Contribution to journalArticle

  34. Chorioamnionitis, neuroinflammation, and injury: timing is key in the preterm ovine fetus

    Gussenhoven, R., Westerlaken, R. J. J., Ophelders, D. R. M. G., Jobe, A. H., Kemp, M. W., Kallapur, S. G., Zimmermann, L. J., Sangild, P. T., Pankratova, S., Gressens, P., Kramer, B. W., Fleiss, B. & Wolfs, T. G. A. M., 19 Apr 2018, In : Journal of neuroinflammation. 15, 1, p. 113

    Research output: Contribution to journalArticle

  35. Cytochrome b5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b5/P450 reductase null (HBRN) mice

    Reed, L., Mrizova, I., Barta, F., Indra, R., Moserova, M., Kopka, K., Schmeiser, H. H., Wolf, C. R., Henderson, C. J., Stiborova, M., Phillips, D. H. & Arlt, V. M., Apr 2018, In : Archives of Toxicology. 92, 4, p. 1625-1638

    Research output: Contribution to journalArticle

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