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Research Outputs

  1. 2008
  2. The environmental pollutant and carcinogen 3-nitrobenzanthrone induces cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in rat lung and kidney, thereby enhancing its own genotoxicity

    Stiborová, M., Dracínská, H., Mizerovská, J., Frei, E., Schmeiser, H. H., Hudecek, J., Hodek, P., Phillips, D. H. & Arlt, V. M., 2 May 2008, In : Toxicology. 247, 1, p. 11 - 22 12 p.

    Research output: Contribution to journalArticle

  3. DNA adducts and cancer risk in prospective studies: a pooled analysis and a meta-analysis

    Veglia, F., Loft, S., Matullo, G., Peluso, M., Munnia, A., Perera, F., Phillips, D. H., Tang, D., Autrup, H., Raaschou-Nielsen, O., Tjønneland, A., Vineis, P. & Genair-EPIC Investigators, May 2008, In : Carcinogenesis. 29, 5, p. 932 - 936 5 p.

    Research output: Contribution to journalArticle

  4. Primary cutaneous apocrine carcinoma - A clinico-pothologic analysis of 24 cases

    Robson, A., Lazar, A. J. F., Ben Nagi, J., Hanby, A., Grayson, W., Feinmesser, M., Granter, S. R., Seed, P., Warneke, C. L., McKee, P. H. & Calonje, E., May 2008, In : American Journal of Surgical Pathology. 32, 5, p. 682 - 690 9 p.

    Research output: Contribution to journalArticle

  5. The relationship between endometrial thickness and outcome of medicated frozen embryo replacement cycles

    El-Toukhy, T., Coomarasamy, A., Khairy, M., Sunkara, K., Seed, P., Khalaf, Y. & Braude, P., Apr 2008, In : Fertility and Sterility. 89, 4, p. 832 - 839 8 p.

    Research output: Contribution to journalArticle

  6. p53-dependent global nucleotide excision repair of cisplatin-induced intrastrand cross links in human cells

    Bhana, S., Hewer, A., Phillips, D. H. & Lloyd, D. R., Mar 2008, In : Mutagenesis. 23, 2, p. 131 - 136 6 p.

    Research output: Contribution to journalArticle

  7. Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH: Cytochrome P450 reductase null mouse

    Stiborova, M., Arlt, V. M., Henderson, C. J., Wolf, C. R., Kotrbova, V., Moserova, M., Hudecek, J., Phillips, D. & Frei, E., 1 Feb 2008, In : Toxicology and Applied Pharmacology. 226, 3, p. 318 - 327 10 p.

    Research output: Contribution to journalArticle

  8. Effects of mixing metal ions on oxidative DNA damage mediated by a Fenton-type reduction

    Moriwaki, H., Osborne, M. R. & Phillips, D. H., Feb 2008, In : Toxicology in Vitro. 22, 1, p. 36 - 44 9 p.

    Research output: Contribution to journalArticle

  9. Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null mice

    Arlt, V. M., Stiborová, M., Henderson, C. J., Thiemann, M., Frei, E., Aimová, D., Singh, R., Gamboa da Costa, G., Schmitz, O. J., Farmer, P. B., Wolf, C. R. & Phillips, D. H., 19 Jan 2008, In : Carcinogenesis. 29, 3, p. 656-665 10 p.

    Research output: Contribution to journalArticle

  10. Identification through microarray gene expression analysis of cellular responses to benzo(a)pyrene and its diol-epoxide that are dependent or independent of p53

    Hockley, S. L., Arlt, V. M., Jahnke, G., Hartwig, A., Giddings, I. & Phillips, D. H., Jan 2008, In : Carcinogenesis. 29, 1, p. 202 - 210 9 p.

    Research output: Contribution to journalArticle

  11. Smoking and breast cancer: is there really a link?

    Phillips, D. H. & Garte, S., Jan 2008, In : Cancer Epidemiology, Biomarkers & Prevention. 17, 1, p. 1-2 2 p.

    Research output: Contribution to journalEditorial

  12. A physiological approach to stimulating labour: PULSE a randomised controlled trial of pulsatile versus continuous oxytocin administration

    Crawshaw, S. E., Baker, P. N., Stanley, C., Safari, F., Seed, P. T., Shennan, A. H. & Tribe, R. M., 2008, In : Reproductive Sciences. 15, 2, p. 71 1 p.

    Research output: Contribution to journalMeeting abstract

  13. 2007
  14. DNA adduct formation in human hepatoma cells treated with 3-nitrobenzanthrone: analysis by the (32)P-postlabeling method

    Kanno, T., Kawanishi, M., Takamura-Enya, T., Arlt, V. M., Phillips, D. H. & Yagi, T., 1 Dec 2007, In : Mutation Research. 634, 1-2, p. 184-91 8 p.

    Research output: Contribution to journalArticle

  15. AHR- and DNA-damage-mediated gene expression responses induced by benzo(a)pyrene in human cell lines

    Hockley, S. L., Arlt, V. M., Brewer, D., Te Poele, R., Workman, P., Giddings, I. & Phillips, D. H., Dec 2007, In : Chemical Research in Toxicology. 20, 12, p. 1797-1810 14 p.

    Research output: Contribution to journalArticle

  16. Fetal arterial and venous Doppler pulsatility index and time averaged velocity ranges

    Parra-Cordero, M., Lees, C., Missfelder-Lobos, H., Seed, P. & Harris, C., Dec 2007, In : Prenatal Diagnosis. 27, 13, p. 1251 - 1257 7 p.

    Research output: Contribution to journalArticle

  17. Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer

    Arlt, V., Stiborová, M., vom Brocke, J., Simões, M. L., Lord, G. M., Nortier, J. L., Hollstein, M., Phillips, D. H. & Schmeiser, H. H., Nov 2007, In : Carcinogenesis. 28, 11, p. 2253 - 2261 9 p.

    Research output: Contribution to journalArticle

  18. Prophylactic antibiotics for the prevention of preterm birth in women at risk: A meta-analysis

    Simcox, R., Sin, W. T. A., Seed, P. T., Briley, A. & Shennan, A. H., Oct 2007, In : Australian and New Zealand Journal of Obstetrics and Gynaecology. 47, 5, p. 368 - 377 10 p.

    Research output: Contribution to journalArticle

  19. Mutagenicity and DNA adduct formation by the urban air pollutant 2-nitrobenzanthrone

    Arlt, V. M., Glatt, H., Gamboa da Costa, G., Reynisson, J., Takamura-Enya, T. & Phillips, D. H., Aug 2007, In : Toxicological Sciences. 98, 2, p. 445-457 13 p., N/A.

    Research output: Contribution to journalArticle

  20. White blood cell count as a predictor of the severity of sickle cell disease during pregnancy.

    Litos, M., Sarris, I., Bewley, S., Seed, P., Okpala, I. & Oteng-Nting, E., Aug 2007, In : European Journal of Obstetrics Gynecology and Reproductive Biology. 133, 2, p. 169 - 172 4 p.

    Research output: Contribution to journalArticle

  21. Formation and persistence of DNA adducts formed by the carcinogenic air pollutant 3-nitrobenzanthrone in target and non-target organs after intratracheal instillation in rats

    Bieler, C. A., Cornelius, M. G., Stiborova, M., Arlt, V. M., Wiessler, M., Phillips, D. H. & Schmeiser, H. H., May 2007, In : Carcinogenesis. 28, 5, p. 1117-21 5 p.

    Research output: Contribution to journalArticle

  22. How do patients referred to neurologists for headache differ from those managed in primary care?

    Ridsdale, L., Clark, C., Dowson, A., Goldstein, L., Jenkins, L., McCrone, P., Morgan, M. & Seed, P., May 2007, In : British Journal of General Practice. 57, 538, p. 388 - 395 8 p.

    Research output: Contribution to journalArticle

  23. Diversity of TMPRSS2-ERG fusion transcripts in the human prostate

    Clark, J., Merson, S., Jhavar, S., Flohr, P., Edwards, S., Foster, C. S., Eeles, R., Martin, F. L., Phillips, D. H., Crundwell, M., Christmas, T., Thompson, A., Fisher, C., Kovacs, G. & Cooper, C. S., 19 Apr 2007, In : Oncogene. 26, 18, p. 2667-2673 7 p.

    Research output: Contribution to journalArticle

  24. Growth kinetics in MCF-7 cells modulate benzo[a]pyrene-induced CYP1A1 up-regulation

    Jiao, H., Allinson, S. L., Walsh, M. J., Hewitt, R., Cole, K. J., Phillips, D. H. & Martin, F. L., Mar 2007, In : Mutagenesis. 22, 2, p. 111-116 6 p.

    Research output: Contribution to journalArticle

  25. Antiplatelet agents for prevention of pre-eclampsia

    Chandiramani, M., Seed, P., Poston, L. & Shennan, A. H., 2007, In : The Lancet. 370, 9600, p. 1685 - 1685 1 p.

    Research output: Contribution to journalLetter

  26. The 32P-postlabeling assay for DNA adducts

    Phillips, D. H. & Arlt, V. M., 2007, In : Nature Protocols. 2, 11, p. 2772-2781 10 p.

    Research output: Contribution to journalArticle

  27. 2006
  28. DNA adduct formation and mutation induction by aristolochic acid in rat kidney and liver

    Mei, N., Arlt, V. M., Phillips, D. H., Heflich, R. H. & Chen, T., 1 Dec 2006, In : Mutation Research. 602, 1-2, p. 83-91 9 p.

    Research output: Contribution to journalArticle

  29. Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2

    Hockley, S. L., Arlt, V. M., Brewer, D., Giddings, I. & Phillips, D. H., 16 Oct 2006, In : BMC GENOMICS. 7, p. 260 260.

    Research output: Contribution to journalArticle

  30. Molecular staging of lymph nodes from 60 patients with mycosis fungoides and Sezary syndrome: correlation with histopathology and outcome suggests prognostic relevance in mycosis fungoides

    Fraser-Andrews, E. A., Mitchell, T., Ferreira, S., Seed, P. T., Russell-Jones, R., Calonje, E. & Whittaker, S. J., Oct 2006, In : British Journal of Dermatology. 155, 4, p. 756 - 762 7 p.

    Research output: Contribution to journalArticle

  31. The effect of small intramural uterine fibroids on the cumulative outcome of assisted conception

    Khalaf, Y., Ross, C., El-Toukhy, T., Hart, R., Seed, P. & Braude, P., Oct 2006, In : Human Reproduction. 21, 10, p. 2640 - 2644 5 p.

    Research output: Contribution to journalArticle

  32. Sex differences in risk of lung cancer: Expression of genes in the PAH bioactivation pathway in relation to smoking and bulky DNA adducts

    Mollerup, S., Berge, G., Baera, R., Skaug, V., Hewer, A., Phillips, D. H., Stangeland, L. & Haugen, A., 15 Aug 2006, In : International Journal of Cancer. 119, 4, p. 741-4 4 p.

    Research output: Contribution to journalArticle

  33. Morbidity in expatriates - a prospective cohort study

    Patel, D., Easmon, C., Seed, P., Dow, C. & Snashall, D., Aug 2006, In : Occupational Medicine. 56, 5, p. 345 - 352 8 p.

    Research output: Contribution to journalArticle

  34. The environmental pollutant and carcinogen 3-nitrobenzanthrone and its human metabolite 3-aminobenzanthrone are potent inducers of rat hepatic cytochromes P450 1A1 and -1A2 and NAD(P)H:quinone oxidoreductase

    Stiborová, M., Dracínská, H., Hájková, J., Kaderábková, P., Frei, E., Schmeiser, H. H., Soucek, P., Phillips, D. H. & Arlt, V. M., Aug 2006, In : Drug Metabolism and Disposition. 34, 8, p. 1398-1405 8 p.

    Research output: Contribution to journalArticle

  35. Msh2 deficiency increases susceptibility to benzo[a]pyrene-induced lymphomagenesis

    Zienolddiny, S., Ryberg, D., Svendsrud, D. H., Eilertsen, E., Skaug, V., Hewer, A., Phillips, D. H., te Riele, H. & Haugen, A., 1 Jun 2006, In : International Journal of Cancer. 118, 11, p. 2899-2902 4 p.

    Research output: Contribution to journalArticle

  36. The expression of xenobiotic-metabolizing enzymes in human prostate and in prostate epithelial cells (PECs) derived from primary cultures

    Al-Buheissi, S. Z., Cole, K. J., Hewer, A., Kumar, V., Bryan, R. L., Hudson, D. L., Patel, H. R., Nathan, S., Miller, R. A. & Phillips, D. H., 1 Jun 2006, In : Prostate. 66, 8, p. 876-885 10 p.

    Research output: Contribution to journalArticle

  37. N-Acetyltransferase and sulfotransferase activity in human prostate: potential for carcinogen activation

    Al-Buheissi, S. Z., Patel, H. R., Meinl, W., Hewer, A., Bryan, R. L., Glatt, H., Miller, R. A. & Phillips, D. H., Jun 2006, In : PHARMACOGENETICS AND GENOMICS. 16, 6, p. 391-399 9 p.

    Research output: Contribution to journalArticle

  38. Identification of three major DNA adducts formed by the carcinogenic air pollutant 3-nitrobenzanthrone in rat lung at the C8 and N2 position of guanine and at the N6 position of adenine

    Arlt, V. M., Schmeiser, H. H., Osborne, M. R., Kawanishi, M., Kanno, T., Yagi, T., Phillips, D. H. & Takamura-Enya, T., 1 May 2006, In : International Journal of Cancer. 118, 9, p. 2139-46 8 p.

    Research output: Contribution to journalArticle

  39. Vitamin C and vitamin E in pregnant women at risk for pre-eclampsia (VIP trial): randomised placebo-controlled trial

    Poston, L., Briley, A. L., Seed, P. T., Kelly, F. J. & Shennan, A. H., 8 Apr 2006, In : The Lancet. 367, 9517, p. 1145 - 1154 10 p.

    Research output: Contribution to journalArticle

  40. Bioactivation of 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone: evidence for DNA adduct formation mediated by cytochrome P450 enzymes and peroxidases

    Arlt, V. M., Henderson, C. J., Wolf, C. R., Schmeiser, H. H., Phillips, D. H. & Stiborova, M., 28 Mar 2006, In : Cancer Letters. 234, 2, p. 220-31 12 p.

    Research output: Contribution to journalArticle

  41. Polymorphisms of DNA repair genes and risk of non-small cell lung cancer

    Zienolddiny, S., Campa, D., Lind, H., Ryberg, D., Skaug, V., Stangeland, L., Phillips, D. H., Canzian, F. & Haugen, A., Mar 2006, In : Carcinogenesis. 27, 3, p. 560-7 8 p.

    Research output: Contribution to journalArticle

  42. Placental NAD(P)H oxidase mediated superoxide generation in early pregnancy

    Raijmakers, M. T. M., Burton, G. J., Jauniaux, E., Seed, P. T., Peters, W. H. M., Steegers, E. A. P. & Poston, L., Feb 2006, In : Placenta. 27, 2-3, p. 158 - 163 6 p.

    Research output: Contribution to journalArticle

  43. A randomised controlled trial of metronidazole for the prevention of preterm birth in women positive for cervicovaginal fetal fibronectin: the PREMET study

    Shennan, A., Crawshaw, S., Briley, A., Hawken, J., Seed, P., Jones, G. & Poston, L., Jan 2006, In : BJOG. 113, 1, p. 65 - 74 10 p.

    Research output: Contribution to journalArticle

  44. Plasma lipid profiles of women with intrahepatic cholestasis of pregnancy

    Dann, A. T., Kenyon, A. P., Wierzbicki, A. S., Seed, P. T., Shennan, A. H. & Tribe, R. M., Jan 2006, In : Obstetrics and Gynecology. 107, 1, p. 106 - 114 9 p.

    Research output: Contribution to journalArticle

  45. 2005
  46. Measuring mental health outcomes in primary care: The psychometric properties of a new patient-generated outcome measure, 'PSYCHLOPS' ('psychological outcome profiles')

    Ashworth, M., Robinson, S. I., Godfrey, E., Shepherd, M., Evans, C., Seed, P., Parmentier, H. & Tylee, A., 1 Dec 2005, In : Primary Care Mental Health. 3, 4, p. 261-270 10 p.

    Research output: Contribution to journalArticle

  47. Interleukin 1 receptor antagonist gene polymorphism and risk of lung cancer: a possible interaction with polymorphisms in the interleukin 1 beta gene

    Lind, H., Zienolddiny, S., Ryberg, D., Skaug, V., Phillips, D. H. & Haugen, A., Dec 2005, In : Lung Cancer. 50, 3, p. 285-290 6 p.

    Research output: Contribution to journalArticle

  48. Molecular mechanism of genotoxicity of the environmental pollutant 3-nitrobenzanthrone

    Stiborová, M., Arlt, V. M., Henderson, C. J., Wolf, C. R., Frei, E., Schmeiser, H. H. & Phillips, D. H., Dec 2005, In : Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia. 149, 2, p. 191-197 7 p., N/A.

    Research output: Contribution to journalArticle

  49. A biomarker model of sublethal genotoxicity (DNA single-strand breaks and adducts) using the sentinel organism Aporrectodea longa in spiked soil

    Martin, F. L., Piearce, T. G., Hewer, A., Phillips, D. H. & Semple, K. T., Nov 2005, In : ENVIRONMENTAL POLLUTION. 138, 2, p. 307-315 9 p.

    Research output: Contribution to journalArticle

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