Gifford, G., Crossley, N., Morgan, S., Kempton, M. J., Dazzan, P., Modinos, G., Azis, M., Samson, C., Bonoldi, I., Quinn, B., Smart, S. E., Antoniades, M., Bossong, M. G., Broome, M. R., Perez, J., Howes, O. D., Stone, J. M., Allen, P., Grace, A. A., & McGuire, P. (2021). Integrated metastate functional connectivity networks predict change in symptom severity in clinical high risk for psychosis. Human Brain Mapping, 42(2), 439-451. https://doi.org/10.1002/hbm.25235

Potkin, S. G., Kane, J. M., Correll, C. U., Lindenmayer, J. P., Agid, O., Marder, S. R., Olfson, M., & Howes, O. D. (2020). The neurobiology of treatment-resistant schizophrenia: paths to antipsychotic resistance and a roadmap for future research. NPJ SCHIZOPHRENIA, 6(1), [1]. https://doi.org/10.1038/s41537-019-0090-z

McCutcheon, R. A., Jauhar, S., Pepper, F., Nour, M. M., Rogdaki, M., Veronese, M., Turkheimer, F. E., Egerton, A., McGuire, P., Mehta, M. M., & Howes, O. D. (2020). The Topography of Striatal Dopamine and Symptoms in Psychosis: An Integrative Positron Emission Tomography and Magnetic Resonance Imaging Study. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 5(11), 1040-1051. https://doi.org/10.1016/j.bpsc.2020.04.004

Howes, O., Whitehurst, T., Shatalina, E., Townsend, L., Onwordi, E. C., Allenis Mak, T. L., Arumuham, A., O'brien, O., Vano, L., Lobo, M., Zahid, U., Butler, E., & Osugo, M. (2020). The clinical significance of duration of untreated psychosis: an umbrella review and random-effects meta-analysis. World Psychiatry.

Wright, P., Veronese, M., Mazibuko, N., Turkheimer, F. E., Rabiner, E. A., Ballard, C. G., Williams, S. C. R., Hari Narayanan, A. K., Osrah, B., Williams, R., Marques, T. R., Howes, O. D., Roncaroli, F., & O'Sullivan, M. J. (2020). Patterns of Mitochondrial TSPO Binding in Cerebral Small Vessel Disease: An in vivo PET Study With Neuropathological Comparison. Frontiers in Neurology, 11, 541377. [541377]. https://doi.org/10.3389/fneur.2020.541377, https://doi.org/10.3389/fneur.2020.541377

Egerton, A., Murphy, A., Donocik, J., Anton, A., Barker, G., Collier, T., Deakin, B., Drake, R., Eliasson, E., Emsley, R., Gregory, C., Griffiths, K., Kapur, S., Kassoumeri, L., Knight, L., Emily, L., Lawrie, S., Lees, J., Lewis, S. W., ... Howes, O. (2020). Dopamine and Glutamate in Antipsychotic-Responsive compared to Antipsychotic Non-Responsive Psychosis: A Multicentre Positron Emission Tomography and Magnetic Resonance Spectroscopy Study (STRATA). Schizophrenia Bulletin. https://doi.org/10.1093/schbul/sbaa128

Rogdaki, M., Gudbrandsen, M., McCutcheon, R. A., Blackmore, C. E., Brugger, S., Ecker, C., Craig, M. C., Daly, E., Murphy, D. G. M., & Howes, O. (2020). Magnitude and heterogeneity of brain structural abnormalities in 22q11.2 deletion syndrome: a meta-analysis. Molecular Psychiatry, 25(8), 1704–1717. https://doi.org/10.1038/s41380-019-0638-3

Robert, G., & Donetto, S. (2020). Whose data is it anyway? Patient experience and service improvement. Journal of Health Services Research and Policy, 25(3), 139-141. https://doi.org/10.1177/1355819620921423

Osimo, E. F., Pillinger, T., Rodriguez, I. M., Khandaker, G. M., Pariante, C. M., & Howes, O. D. (2020). Inflammatory markers in depression: A meta-analysis of mean differences and variability in 5,166 patients and 5,083 controls. Brain, Behavior, and Immunity, 87, 901-909. https://doi.org/10.1016/j.bbi.2020.02.010

Vinkers, C. H., van Amelsvoort, T., Bisson, J. I., Branchi, I., Cryan, J. F., Domschke, K., Howes, O. D., Manchia, M., Pinto, L., de Quervain, D., Schmidt, M. V., & van der Wee, N. J. A. (2020). Stress resilience during the coronavirus pandemic. European Neuropsychopharmacology, 35, 12-16. https://doi.org/10.1016/j.euroneuro.2020.05.003

Howes, O., Kokkinou, M., Natesan, S., Irving, E., Bonsall, D. R., Wells, L. A., Smith, M., Glegola, J., Paul, E., Tossell, K., Veronese, M., Khadayate, S., Dedic, N., Hopkins, S., Ungless, M. A., & Withers, D. J. (2020). Reproducing the dopamine pathophysiology of schizophrenia and approaches to ameliorate it: a translational imaging study with ketamine. Molecular Psychiatry, 0(0), 1-15. https://doi.org/10.1038/s41380-020-0740-6

Beck, K., Hindley, G., Borgan, F., Ginestet, C., McCutcheon, R., Brugger, S., Driesen, N., Ranganathan, M., D'Souza, D. C., Taylor, M., Krystal, J. H., & Howes, O. D. (2020). Association of Ketamine With Psychiatric Symptoms and Implications for Its Therapeutic Use and for Understanding Schizophrenia: A Systematic Review and Meta-analysis. JAMA Network open, 3(5), e204693. https://doi.org/10.1001/jamanetworkopen.2020.4693

Hindley, G., Beck, K., Borgan, F., Ginestet, C., McCutcheon, R., Kleinloog, D., Ganesh, S., Radhakrishnan, R., D'Souza, D. C., & Howes, O. D. (2020). Psychiatric symptoms caused by cannabis constituents: a systematic review and meta- analysis. The Lancet Psychiatry, 7(4), 344-353. https://doi.org/10.1016/S2215-0366(20)30074-2

Reis Marques, T., Borgan, F., Ashok, A. H., Ureche-Angelescu, I., Meyers, J., Lingford-Hughes, A., Nutt, D., Veronese, M., Turkheimer, F. E., & Howes, O. (2020). GABA-A receptor differences in Schizophrenia: A Positron Emission Tomography study using [11C]Ro154513. Molecular Psychiatry, 0(0), 1-10. https://doi.org/10.1038/s41380-020-0711-y

Adams, R. A., Bush, D., Zheng, F., Meyer, S. S., Kaplan, R., Orfanos, S., Marques, T. R., Howes, O. D., & Burgess, N. (2020). Impaired theta phase coupling underlies frontotemporal dysconnectivity in schizophrenia. Brain : a journal of neurology, 143(3), 1261-1277. https://doi.org/10.1093/brain/awaa035

Howes, O. D., Bonoldi, I., McCutcheon, R. A., Azis, M., Antoniades, M., Bossong, M., Modinos, G., Perez, J., Stone, J. M., Santangelo, B., Veronese, M., Grace, A., Allen, P., & McGuire, P. K. (2020). Glutamatergic and dopaminergic function and the relationship to outcome in people at clinical high risk of psychosis: a multi-modal PET-magnetic resonance brain imaging study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 45(4), 641-648. https://doi.org/10.1038/s41386-019-0541-2

McCutcheon, R. A., Krystal, J. H., & Howes, O. D. (2020). Dopamine and glutamate in schizophrenia: biology, symptoms and treatment. World Psychiatry, 19(1), 15-33. https://doi.org/10.1002/wps.20693

Pillinger, T., McCutcheon, R. A., Vano, L., Mizuno, Y., Arumuham, A., Hindley, G., Beck, K., Natesan, S., Efthimiou, O., Cipriani, A., & Howes, O. D. (2020). Comparative effects of 18 antipsychotics on metabolic function in patients with schizophrenia, predictors of metabolic dysregulation, and association with psychopathology: a systematic review and network meta-analysis. The Lancet Psychiatry, 7(1), 64-77. https://doi.org/10.1016/S2215-0366(19)30416-X

Barnes, T. R., Drake, R., Paton, C., Cooper, S. J., Deakin, B., Ferrier, I. N., Gregory, C. J., Haddad, P. M., Howes, O. D., Jones, I., Joyce, E. M., Lewis, S., Lingford-Hughes, A., MacCabe, J. H., Owens, D. C., Patel, M. X., Sinclair, J. M., Stone, J. M., Talbot, P. S., ... Yung, A. R. (2020). Evidence-based guidelines for the pharmacological treatment of schizophrenia: Updated recommendations from the British Association for Psychopharmacology. Journal of psychopharmacology (Oxford, England), 34(1), 3-78. https://doi.org/10.1177/0269881119889296

Onwordi, E. C., Halff, E. F., Whitehurst, T., Mansur, A., Cotel, M-C., Wells, L. A., Creeney, H., Bonsall, D. R., Rogdaki, M., Shatalina, E., Reis Marques, T., Rabiner, E., Gunn, R. N., Natesan, S., Vernon, A. C., & Howes, O. D. (2020). Synaptic density marker SV2A is reduced in schizophrenia patients and unaffected by antipsychotics in rats. Nature Communications, 11(1), 1-11. [246]. https://doi.org/10.1038/s41467-019-14122-0

Borgan, F., O'Daly, O., Veronese, M., Reis Marques, T., Laurikainen, H., Hietala, J., & Howes, O. (2019). The neural and molecular basis of working memory function in psychosis: a multimodal PET-fMRI study. Molecular Psychiatry. https://doi.org/10.1038/s41380-019-0619-6

Petty, A., Cui, X., Tesiram, Y., Kirik, D., Howes, O., & Eyles, D. (2019). Enhanced Dopamine in Prodromal Schizophrenia (EDiPS): a new animal model of relevance to schizophrenia. NPJ SCHIZOPHRENIA, 5(1), [6]. https://doi.org/10.1038/s41537-019-0074-z

Kaar, S. J., Angelescu, I., Marques, T. R., & Howes, O. D. (2019). Pre-frontal parvalbumin interneurons in schizophrenia: a meta-analysis of post-mortem studies. Journal of Neural Transmission, 126(12), 1637-1651. https://doi.org/10.1007/s00702-019-02080-2

IMPACT team (2019). Effect of lifestyle, medication and ethnicity on cardiometabolic risk in the year following the first episode of psychosis: prospective cohort study. British Journal of Psychiatry, 215(6), 712-719. https://doi.org/10.1192/bjp.2019.159

McCutcheon, R. A., Mizuno, Y., Brugger, S. P., & Howes, O. D. (2019). Heterogeneity and efficacy of antipsychotic treatment for schizophrenia with or without treatment resistance: A meta-analysis. Neuropsychopharmacology. https://doi.org/10.1038/s41386-019-0577-3

D'Ambrosio, E., Jauhar, S., Kim, S., Veronese, M., Rogdaki, M., Pepper, F., Bonoldi, I., Kotoula, V., Kempton, M. J., Turkheimer, F., Kwon, J. S., Kim, E., & Howes, O. D. (2019). The relationship between grey matter volume and striatal dopamine function in psychosis: a multimodal 18F-DOPA PET and voxel-based morphometry study. Molecular Psychiatry, 00, 1. https://doi.org/10.1038/s41380-019-0570-6

Pillinger, T., McCutcheon, R. A., Vano, L. J., Mizuno, Y., Arumuham, A., Hindley, G. F. L., Beck, K. E., Natesan, S., Efthimiou, O., Cipriani, A., & Howes, O. D. (Accepted/In press). Comparative effects of 18 antipsychotics on metabolic function in schizophrenia, predictors of metabolic dysregulation, and association with psychopathology: a systematic review and network meta-analysis. The Lancet Psychiatry.

Ashok, A. H., Myers, J., Reis Marques, T., Rabiner, E. A., & Howes, O. (2019). Reduced mu opioid receptor availability in schizophrenia revealed with [¹¹C]-carfentanil Positron Emission Tomographic Imaging. Nature Communications, 10(1), [4493]. https://doi.org/10.1038/s41467-019-12366-4

Donetto, S., Desai, A., Zoccatelli, G., Robert, G., Allen, D., Brearley, S., & Rafferty, A. M. (2019). Organisational strategies and practices to improve care using patient experience data in acute NHS hospital trusts: an ethnographic study. Health Services And Delivery Research, 7(34). https://doi.org/10.3310/hsdr07340

D'Ambrosio, E., Dahoun, T., Pardiñas, A. F., Veronese, M., Bloomfield, M. A. P., Jauhar, S., Bonoldi, I., Rogdaki, M., Froudist-Walsh, S., Walters, J. T. R., & Howes, O. D. (2019). The effect of a genetic variant at the schizophrenia associated AS3MT/BORCS7 locus on striatal dopamine function: A PET imaging study. Psychiatry Research - Neuroimaging, 291, 34-41. https://doi.org/10.1016/j.pscychresns.2019.07.005

Pillinger, T., Osimo, E. F., Brugger, S., Mondelli, V., McCutcheon, R. A., & Howes, O. D. (2019). A Meta-analysis of Immune Parameters, Variability, and Assessment of Modal Distribution in Psychosis and Test of the Immune Subgroup Hypothesis. Schizophrenia Bulletin, 45(5), 1120-1133. https://doi.org/10.1093/schbul/sby160

Kjellström, S., Areskoug-Josefsson , K., Andersson Gäre , B., Andersson, A-C., Ockander, M., Käll, J., McGrath, J., Donetto, S., & Robert, G. (2019). Exploring, measuring and enhancing the coproduction of health and well-being at the national, regional and local levels through comparative case studies in Sweden and England: the 'Samskapa' research programme protocol. BMJ Open, 9(7), e029723. https://doi.org/10.1136/bmjopen-2019-029723

Borgan, F. R., Jauhar, S., McCutcheon, R. A., Pepper, F. S., Rogdaki, M., Lythgoe, D. J., & Howes, O. D. (2019). Glutamate levels in the anterior cingulate cortex in un-medicated first episode psychosis: a proton magnetic resonance spectroscopy study. Scientific Reports, 9(1), [8685 ]. https://doi.org/10.1038/s41598-019-45018-0

Merritt, K. S., Perez-Iglesias, R., Sendt, K-V., Goozee, R. M., Jauhar, S., Pepper, F. S., Barker, G. J., Glenthøj, B., Arango, C., Lewis, S. W., Kahn, R. S., Stone, J. M., Howes, O. D., Dazzan, P., McGuire, P., & Egerton, A. (Accepted/In press). Remission from antipsychotic treatment in first episode psychosis related to longitudinal changes in brain glutamate: Remission in psychosis related to change in glutamate. NPJ SCHIZOPHRENIA.

Nour, M., Dahoun, T., McCutcheon, R. A., Adams, R., Wall, M., & Howes, O. D. (Accepted/In press). Task-induced functional brain connectivity mediates the relationship between striatal D2/3 receptors and working memory. eLife.

Pillinger, T., Osimo, E. F., de Marvao, A., Berry, A., Whitehurst, T., Statton, B., Quinlan, M., Brugger, S., Vazir, A., Cook, S., O'Regan, D., & Howes, O. D. (2019). Cardiac structure and function in patients with schizophrenia taking antipsychotic drugs: an MRI study. Translational psychiatry, 9(1), [163]. https://doi.org/10.1038/s41398-019-0502-x

Bonoldi, I., Allen, P., Madeira, L., Tognin, S., Bossong, M. G., Azis, M., Samson, C., Quinn, B., Calem, M., Valmaggia, L., Modinos, G., Stone, J., Perez, J., Howes, O., Politi, P., Kempton, M. J., Fusar-Poli, P., & McGuire, P. (2019). Basic Self-Disturbances Related to Reduced Anterior Cingulate Volume in Subjects at Ultra-High Risk for Psychosis. Frontiers in Psychiatry, 10(MAY), [254]. https://doi.org/10.3389/fpsyt.2019.00254

Jauhar, S., & Howes, O. D. (2019). Understanding and Predicting Variability in Response to Treatment in Psychotic Disorders: In Vivo Findings. Clinical Pharmacology and Therapeutics, 105(5), 1079-1081. https://doi.org/10.1002/cpt.1357

McCutcheon, R. A., Nour, M. M., Dahoun, T., Jauhar, S., Pepper, F., Expert, P., Veronese, M., Adams, R. A., Turkheimer, F., Mehta, M. A., & Howes, O. D. (2019). Mesolimbic Dopamine Function Is Related to Salience Network Connectivity: An Integrative Positron Emission Tomography and Magnetic Resonance Study. Biological psychiatry, 85(5), 368-378. https://doi.org/10.1016/j.biopsych.2018.09.010

McCutcheon, R. A., Abi-Dargham, A., & Howes, O. D. (2019). Schizophrenia, Dopamine and the Striatum: From Biology to Symptoms. Trends in Neurosciences, 42(3), 205-220. https://doi.org/10.1016/j.tins.2018.12.004

Lally, J., Ajnakina, O., Singh, N., Gardner-Sood, P., Stubbs, B., Stringer, D., Di Forti, M., David, A. S., Smith, S., Murray, R. M., Howes, O. D., & Gaughran, F. (2019). Vitamin D and clinical symptoms in First Episode Psychosis (FEP): a prospective cohort study. Schizophrenia Research, 204, 381-388. https://doi.org/10.1016/j.schres.2018.08.011

Ashok, A. H., Mizuno, Y., & Howes, O. D. (2019). Tobacco smoking and dopaminergic function in humans: A meta-analysis of molecular imaging studies. Psychopharmacology. https://doi.org/10.1007/s00213-019-05196-1

Shin, S., Kim, S., Seo, S., Lee, J. S., Howes, O. D., Kim, E., & Kwon, J. S. (2018). The relationship between dopamine receptor blockade and cognitive performance in schizophrenia: A [¹¹C]-raclopride PET study with aripiprazole. Translational psychiatry, 8(1), [87]. https://doi.org/10.1038/s41398-018-0134-6

Reis Marques, T., Ashok, A. H., Pillinger, T., Veronese, M., Turkheimer, F. E., Dazzan, P., Sommer, I. E. C., & Howes, O. D. (2018). Neuroinflammation in schizophrenia: meta-analysis of in-vivo microglial imaging studies. Psychological Medicine. https://doi.org/10.1017/S0033291718003057

McCutcheon, R., Beck, K., Jauhar, S., & Howes, O. D. (2018). Defining the Locus of Dopaminergic Dysfunction in Schizophrenia: A Meta-analysis and Test of the Mesolimbic Hypothesis. Schizophrenia Bulletin, 44(6), 1301-1311. https://doi.org/10.1093/schbul/sbx180

Allen, P., Azis, M., Modinos, G., Bossong, M. G., Bonoldi, I., Samson, C., Quinn, B., Kempton, M. J., Howes, O. D., Stone, J. M., Calem, M., Perez, J., Bhattacharayya, S., Broome, M. R., Grace, A. A., Zelaya, F., & McGuire, P. (2018). Increased Resting Hippocampal and Basal Ganglia Perfusion in People at Ultra High Risk for Psychosis: Replication in a Second Cohort. Schizophrenia Bulletin, 44(6), 1323–1331. https://doi.org/10.1093/schbul/sbx169

Nour, M., Dahoun, T., Schwartenbeck, P., Adams, R., FitzGerald, T., Coello, C., Wall, M., Dolan, R. J., & Howes, O. D. (2018). Dopaminergic basis for signalling belief updates, but not surprise, and the link to paranoia. Proceedings of the National Academy of Sciences of the United States of America, 43, E10167-E10176. https://doi.org/10.1073/pnas.1809298115

Horder, J., Andersson, M., Mendez Hernandez, M. A., Singh, N., Tangen, A., Lundberg, J., Gee, A., Halldin, C., Veronese, M., Bolte, S., Farde, L., Sementa, T., Cash, D., K, H., Spain, D., Turkheimer, F., Mick, I., Selvaraj, S., Nutt, DJ., ... Borg, J. (2018). GABA_A receptor availability is not altered In adults with autism spectrum disorder or in mouse models. Science Translational Medicine, 10(461), [eaam8434]. https://doi.org/10.1126/scitranslmed.aam8434

Modinos, G., Şimşek, F., Azis, M., Bossong, M., Bonoldi, I., Samson, C., Quinn, B., Perez, J., Broome, M. R., Zelaya, F., Lythgoe, D. J., Howes, O. D., Stone, J. M., Grace, A. A., Allen, P., & McGuire, P. (2018). Correction: Prefrontal GABA levels, hippocampal resting perfusion and the risk of psychosis. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. https://doi.org/10.1038/s41386-018-0118-5

Jauhar, S., McCutcheon, R., Borgan, F., Veronese, M., Nour, M., Pepper, F., Rogdaki, M., Stone, J., Egerton, A., Turkheimer, F., McGuire, P., & Howes, O. D. (2018). The relationship between cortical glutamate and striatal dopamine in first-episode psychosis: a cross-sectional multimodal PET and magnetic resonance spectroscopy imaging study. The Lancet Psychiatry, 5(10), 816-823. https://doi.org/10.1016/S2215-0366(18)30268-2