King's College London

Research portal

Research Outputs

  1. 2019
  2. Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum

    Bos, I., Vos, S., Verhey, F., Scheltens, P., Teunissen, C., Engelborghs, S., Sleegers, K., Frisoni, G., Blin, O., Richardson, J. C., Bordet, R., Tsolaki, M., Popp, J., Peyratout, G., Martinez-Lage, P., Tainta, M., Lleó, A., Johannsen, P., Freund-Levi, Y., Frölich, L. & 12 othersVandenberghe, R., Westwood, S., Dobricic, V., Barkhof, F., Legido-Quigley, C., Bertram, L., Lovestone, S., Streffer, J., Andreasson, U., Blennow, K., Zetterberg, H. & Visser, P. J., 1 May 2019, In : Alzheimer's and Dementia. 15, 5, p. 644-654 11 p.

    Research output: Contribution to journalArticle

  3. 2018
  4. Stability of graph theoretical measures in structural brain networks in Alzheimer’s disease

    Mårtensson, G., Pereira, J. B., Mecocci, P., Vellas, B., Tsolaki, M., Kłoszewska, I., Soininen, H., Lovestone, S., Simmons, A., Volpe, G. & Westman, E., 1 Dec 2018, In : Scientific Reports. 8, 1, 11592.

    Research output: Contribution to journalArticle

  5. MRI predictors of amyloid pathology: Results from the EMIF-AD Multimodal Biomarker Discovery study

    Ten Kate, M., Redolfi, A., Peira, E., Bos, I., Vos, S. J., Vandenberghe, R., Gabel, S., Schaeverbeke, J., Scheltens, P., Blin, O., Richardson, J. C., Bordet, R., Wallin, A., Eckerstrom, C., Molinuevo, J. L., Engelborghs, S., Van Broeckhoven, C., Martinez-Lage, P., Popp, J., Tsolaki, M. & 17 othersVerhey, F. R. J., Baird, A. L., Legido-Quigley, C., Bertram, L., Dobricic, V., Zetterberg, H., Lovestone, S., Streffer, J., Bianchetti, S., Novak, G. P., Revillard, J., Gordon, M. F., Xie, Z., Wottschel, V., Frisoni, G., Visser, P. J. & Barkhof, F., 27 Sep 2018, In : Alzheimer's Research and Therapy. 10, 1, 100.

    Research output: Contribution to journalArticle

  6. Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology

    Smith, R. G., Hannon, E., De Jager, P. L., Chibnik, L., Lott, S. J., Condliffe, D., Smith, A. R., Haroutunian, V., Troakes, C., Al-Sarraj, S., Bennett, D. A., Powell, J., Lovestone, S., Schalkwyk, L., Mill, J. & Lunnon, K., 15 Mar 2018, In : Alzheimer's & Dementia.

    Research output: Contribution to journalArticle

  7. Heterogeneous patterns of brain atrophy in Alzheimer's disease

    Poulakis, K., Pereira, J. B., Mecocci, P., Vellas, B., Tsolaki, M., Kłoszewska, I., Soininen, H., Lovestone, S., Simmons, A., Wahlund, L-O. & Westman, E., 31 Jan 2018, In : Neurobiology of Aging.

    Research output: Contribution to journalArticle

  8. 2017
  9. Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease

    Horgusluoglu-Moloch, E., Nho, K., Risacher, S. L., Kim, S., Foroud, T., Shaw, L. M., Trojanowski, J. Q., Aisen, P. S., Petersen, R. C., Jack, C. R., Lovestone, S., Simmons, A., Weiner, M. W. & Saykin, A. J., 1 Dec 2017, In : Neurobiology of Aging. 60, p. 92-103 12 p.

    Research output: Contribution to journalArticle

  10. DISCOVERY, REPLICATION AND EXTENSION STUDY OF PLASMA PROTEOMIC BIOMARKERS RELATING TO BRAIN AMYLOID BURDEN (CSF Aβ OR AMYLOID-PET) IN THE EMIF-AD BIOMARKER DISCOVERY COHORT: 2017 Abstract Supplement

    Westwood, S., Baird, A. L., Hye, A., Bos, I., Vos, S. J. B., Vandenberghe, R., Scheltens, P., Engelborghs, S., Frisoni, G. B., Molinuevo, J. L., Wallin, A., Lleó, A., Popp, J., Martinez-Lage, P., Snowden, S. G., Legido-Quigley, C., Bertram, L., Barkhof, F., Zetterberg, H., Streffer, J. & 2 othersVisser, P. J. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P361-P362

    Research output: Contribution to journalArticle

  11. PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY: 2017 Abstract Supplement

    Koychev, I. G., Gunn, R. N., Firouzian, A., Lawson, J., Zamboni, G., Ridha, B. H., Sahakian, B., Rowe, J. B., Thomas, A., Rochester, L., Ffytche, D., Howard, R. J., Zetterberg, H., MacKay, C. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P243

    Research output: Contribution to journalPoster abstract

  12. PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY: 2017 Abstract Supplement

    Koychev, I. G., Gunn, R. N., Firouzian, A., Lawson, J., Zamboni, G., Ridha, B. H., Sahakian, B., Rowe, J. B., Thomas, A., Rochester, L., Ffytche, D., Howard, R. J., Zetterberg, H., MacKay, C. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P456-P457

    Research output: Contribution to journalPoster abstract

  13. Amyloid beta synaptotoxicity is Wnt–planar cell polarity dependent and blocked by fasudil

    Sellers, K. J., Elliott, C., Jackson, J., Ghosh, A., Ribe, E., Rojo-Sanchís, A., Jarosz-Griffiths, H. H., Watson, I. A., Xia, W., Semenov, M., Morin, P., Hooper, N. M., Porter, R., Preston, J., Al-Shawi, R., Baillie, G., Lovestone, S., Cuadrado, A., Harte, M., Simons, P. & 2 othersSrivastava, D. P. & Killick, R., 19 Oct 2017, In : Alzheimer's & Dementia.

    Research output: Contribution to journalArticle

  14. EXPLORING THE RELATIONSHIP BETWEEN ANAEMIA AND ALZHEIMER’S DISEASE: 2017 Abstract Supplement

    Winchester, L., Nevado-Holgado, A. J. & Lovestone, S., 20 Jul 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P221

    Research output: Contribution to journalMeeting abstract

  15. NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology

    Rojo, A. I., Pajares, M., Rada, P., Nuñez, A., Nevado-Holgado, A. J., Killik, R., Van Leuven, F., Ribe, E., Lovestone, S., Yamamoto, M. & Cuadrado, A., 5 Jul 2017, In : Redox Biology.

    Research output: Contribution to journalArticle

  16. DISCOVERY AND VALIDATION OF MULTIMODAL BIOMARKER SIGNATURES RELATING TO ALZHEIMER'S DISEASE PATHOLOGY AND PROGRESSION: 2017 Abstract Supplement

    Westwood, S., Hye, A., Lleó, A., Nevado-Holgado, A. J., Baird, A. L., Wallin, A., Leslie, A., Jimenez, B., Liu, B. Y., Legido-Quigley, C., Dima, D., Ruvolo, D., Holmes, E., D'Hondt, E., Westman, E., Barkhof, F., Frisoni, G. B., Zetterberg, H., Bos, I., Pearce, J. & 27 othersStreffer, J., Molinuevo, J. L., Popp, J., Bertram, L., Whiley, L., Maslen, L., Gomez-Romero, M., David, M., Lewis, M., Kurbatova, N., Ashton, N. J., Voyle, N., Kowalczyk, O., Martinez-Lage, P., Proitsi, P., Scheltens, P., Visser, P. J., Dobson, R. JB., Vandenberghe, R., Engelborghs, S., Vos, S. J. B., Snowden, S. G., Athersuch, T., Ashby, T., Kimhofer, T., Verachtert, W. & Lovestone, S., Jul 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P174-P175

    Research output: Contribution to journalMeeting abstract

  17. Mitochondrial genes are altered in blood early in Alzheimer's disease

    Lunnon, K., Keohane, A., Pidsley, R., Newhouse, S., Riddoch-Contreras, J., Thubron, E. B., Devall, M., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Schalkwyk, L., Dobson, R., Malik, A. N., Powell, J., Lovestone, S. & Hodges, A., 1 May 2017, In : Neurobiology of Aging. 53, p. 36-47 12 p.

    Research output: Contribution to journalArticle

  18. A Multi-Cohort Study of ApoE ϵ 4 and Amyloid-β Effects on the Hippocampus in Alzheimer's Disease

    Khan, W., Giampietro, V., Banaschewski, T., Barker, G. J., Bokde, A. L. W., Büchel, C., Conrod, P., Flor, H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Lemaître, H., Nees, F., Paus, T., Pausova, Z., Rietschel, M., Smolka, M. N., Ströhle, A. & 19 othersGallinat, J., Vellas, B., Soininen, H., Kloszewska, I., Tsolaki, M., Mecocci, P., Spenger, C., Villemagne, V. L., Masters, C. L., Muehlboeck, J. S., Bäckman, L., Fratiglioni, L., Kalpouzos, G., Wahlund, L. O., Schumann, G., Lovestone, S., Williams, S. C. R., Westman, E. & Simmons, A., 3 Feb 2017, In : JOURNAL OF ALZHEIMERS DISEASE. 56, 3, p. 1159-1174 16 p.

    Research output: Contribution to journalArticle

  19. Novel genetic loci associated with hippocampal volume

    Hibar, D. P., Adams, H. H. H., Jahanshad, N., Chauhan, G., Stein, J. L., Hofer, E., Renteria, M. E., Bis, J. C., Arias-Vasquez, A., Ikram, M. K., Desrivières, S., Vernooij, M. W., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S., Armstrong, N. J., Athanasiu, L. & 312 othersAxelsson, T., Beecham, A. H., Beiser, A., Bernard, M., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chen, Q., Ching, C. R. K., Chouraki, V., Cuellar-Partida, G., Crivello, F., Den Braber, A., Doan, N. T., Ehrlich, S., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Grimm, O., Griswold, M. E., Guadalupe, T., Gutman, B. A., Hass, J., Haukvik, U. K., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Jørgensen, K. N., Karbalai, N., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liewald, D. C. M., Lopez, L. M., Luciano, M., Macare, C., Marquand, A. F., Matarin, M., Mather, K. A., Mattheisen, M., McKay, D. R., Milaneschi, Y., Muñoz Maniega, S., Nho, K., Nugent, A. C., Nyquist, P., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pirpamer, L., Pütz, B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Ropele, S., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Saremi, A., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Trompet, S., Vaidya, D., Van der Grond, J., Van der Lee, S. J., Van der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Wittfeld, K., Woldehawariat, G., Wolf, C., Wolfers, T., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Cheng, C-Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Craen, A. J. M., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Deary, I. J., Debette, S., DeCarli, C., Delanty, N., Depondt, C., DeStefano, A., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Enzinger, C., Erk, S., Espeseth, T., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Fornage, M., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Håberg, A. K., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B-C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J-J., Huentelman, M., Pol, H. E. H., Ikeda, M., Jack, C. R., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J-L., Mattay, V. S., McDonald, C., McIntosh, A. M., McMahon, F. J., McMahon, K. L., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-Seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schmidt, H., Schofield, P. R., Sigursson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J., Tsolaki, M., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., Van der Brug, M., van der Lugt, A., van der Wee, N. J. A., Van Haren, N. E. M., van 't Ent, D., Van Tol, M-J., Vardarajan, B. N., Vellas, B., Veltman, D. J., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, R. H., Zonderman, A. B., Martin, N. G., Van Duijn, C. M., Wright, M. J., Longstreth, W. T., Schumann, G., Grabe, H. J., Franke, B., Launer, L. J., Medland, S. E., Seshadri, S., Thompson, P. M. & Ikram, M. A., 18 Jan 2017, In : Nature Communications. 8, p. 13624 12 p.

    Research output: Contribution to journalArticle

  20. 2016
  21. Better together for better dementia research and care

    Lovestone, S., Rossor, M., Gallacher, J., Ritchie, C., Burn, D., Hyslop, P. S. G., Mackay, C., Matthews, P. M., Ballard, C. & Georges, J., 17 May 2016, In : The Lancet Psychiatry.

    Research output: Contribution to journalComment/debate

  22. Shared genetic contribution to ischemic stroke and Alzheimer's disease: Ischemic Stroke and Alzheimer's Disease

    Traylor, M., Adib-samii, P., Harold, D., Dichgans, M., Williams, J., Lewis, C. M., Markus, H. S., METASTROKE and International Genomics of Alzheimer's Project (IGAP) investigators, Lovestone, S. H. & Proitsi, P., 1 May 2016, In : Annals of Neurology. 79, 5, p. 739-747

    Research output: Contribution to journalArticle

  23. Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease

    Allen, G. I., Amoroso, N., Anghel, C., Balagurusamy, V., Bare, C. J., Beaton, D., Bellotti, R., Bennett, D. A., Boehme, K. L., Boutros, P. C., Caberlotto, L., Caloian, C., Campbell, F., Chaibub Neto, E., Chang, Y-C., Chen, B., Chen, C-Y., Chien, T-Y., Clark, T., Das, S. & 81 othersDavatzikos, C., Deng, J., Dillenberger, D., Dobson, R. J. B., Dong, Q., Doshi, J., Duma, D., Errico, R., Erus, G., Everett, E., Fardo, D. W., Friend, S. H., Fröhlich, H., Gan, J., St George-Hyslop, P., Ghosh, S. S., Glaab, E., Green, R. C., Guan, Y., Hong, M-Y., Huang, C., Hwang, J., Ibrahim, J., Inglese, P., Iyappan, A., Jiang, Q., Katsumata, Y., Kauwe, J. S. K., Klein, A., Kong, D., Krause, R., Lalonde, E., Lauria, M., Lee, E., Lin, X., Liu, Z., Livingstone, J., Logsdon, B. A., Lovestone, S., Ma, T., Malhotra, A., Mangravite, L. M., Maxwell, T. J., Merrill, E., Nagorski, J., Namasivayam, A., Narayan, M., Naz, M., Newhouse, S. J., Norman, T. C., Nurtdinov, R. N., Oyang, Y-J., Pawitan, Y., Peng, S., Peters, M. A., Piccolo, S. R., Praveen, P., Priami, C., Sabelnykova, V. Y., Senger, P., Shen, X., Simmons, A., Sotiras, A., Stolovitzky, G., Tangaro, S., Tateo, A., Tung, Y-A., Tustison, N. J., Varol, E., Vradenburg, G., Weiner, M. W., Xiao, G., Xie, L., Xie, Y., Xu, J., Yang, H., Zhan, X., Zhou, Y., Zhu, F., Zhu, H. & Zhu, S., 11 Apr 2016, In : Alzheimer's & Dementia. 12, 6, p. 645-653 9 p.

    Research output: Contribution to journalArticle

  24. The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume

    Lupton, M. K., Strike, L., Hansell, N. K., Wen, W., Mather, K. A., Armstrong, N. J., Thalamuthu, A., McMahon, K. L., de Zubicaray, G. I., Assareh, A. A., Simmons, A., Proitsi, P., Powell, J. F., Montgomery, G. W., Hibar, D. P., Westman, E., Tsolaki, M., Kloszewska, I., Soininen, H., Mecocci, P. & 9 othersVelas, B., Lovestone, S., Brodaty, H., Ames, D., Trollor, J. N., Martin, N. G., Thompson, P. M., Sachdev, P. S. & Wright, M. J., 1 Apr 2016, In : Neurobiology of Aging. 40, p. 68-77 10 p.

    Research output: Contribution to journalArticle

  25. The Effect of Age Correction on Multivariate Classification in Alzheimer’s Disease, with a Focus on the Characteristics of Incorrectly and Correctly Classified Subjects

    Falahati, F., Ferreira, D., Soininen, H., Mecocci, P., Vellas, B., Tsolaki, M., Kłoszewska, I., Lovestone, S., Eriksdotter, M., Wahlund, L. O., Simmons, A. & Westman, E., 1 Mar 2016, In : Brain topography. 29, 2, p. 296-307 12 p.

    Research output: Contribution to journalArticle

  26. Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept

    Psychosis Endophenotypes International Consortium, 23 Feb 2016, In : Nature Neuroscience. 19, 3, p. 420-431 12 p.

    Research output: Contribution to journalArticle

  27. A pathway based classification method for analyzing gene expression for Alzheimer's disease diagnosis

    Voyle, N., Keohane, A., Newhouse, S., Lunnon, K., Johnston, C., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Hodges, A., Kiddle, S. & Dobson, R. JB., 2016, In : JOURNAL OF ALZHEIMERS DISEASE. 49, 3, p. 659-669 11 p.

    Research output: Contribution to journalArticle

  28. Novel genetic loci underlying human intracranial volume identified through genome-wide association

    Adams, H. H. H., Hibar, D. P., Chouraki, V., Stein, J. L., Nyquist, P. A., Rentería, M. E., Trompet, S., Arias-vasquez, A., Seshadri, S., Desrivières, S., Beecham, A. H., Jahanshad, N., Wittfeld, K., Van Der Lee, S. J., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S. & 322 othersArmstrong, N. J., Athanasiu, L., Axelsson, T., Beiser, A., Bernard, M., Bis, J. C., Blanken, L. M. E., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chauhan, G., Chen, Q., Ching, C. R. K., Cuellar-partida, G., Braber, A. D., Doan, N. T., Ehrlich, S., Filippi, I., Ge, T., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Greven, C. U., Grimm, O., Griswold, M. E., Guadalupe, T., Hass, J., Haukvik, U. K., Hilal, S., Hofer, E., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liao, J., Liewald, D. C. M., Lopez, L. M., Luciano, M., Macare, C., Marquand, A., Matarin, M., Mather, K. A., Mattheisen, M., Mazoyer, B., Mckay, D. R., Mcwhirter, R., Milaneschi, Y., Mirza-schreiber, N., Muetzel, R. L., Maniega, S. M., Nho, K., Nugent, A. C., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pappa, I., Pirpamer, L., Pudas, S., Pütz, B., Rajan, K. B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-santiañez, R., Rommelse, N., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Thomson, R., Tordesillas-gutierrez, D., Toro, R., Trabzuni, D., Vaidya, D., Van Der Grond, J., Van Der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Woldehawariat, G., Wolf, C., Wolfers, T., Xu, B., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Aggarwal, N. T., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., Van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Chen, C., Cheng, C., Cichon, S., Cookson, M. R., Corvin, A., Crespo-facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Delanty, N., Depondt, C., Destefano, A. L., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Erk, S., Espeseth, T., Evans, D. A., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Grabe, H. J., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J., Pol, H. E. H., Ikeda, M., Ikram, M. K., Jack, C. R., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Longstreth, W. T., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J., Mattay, V. S., Mcdonald, C., Mcintosh, A. M., Mcmahon, K. L., Mcmahon, F. J., Mecocci, P., Melle, I., Meyer-lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schofield, P. R., Sigurdsson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Srikanth, V., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Tiemeier, H., Toga, A. W., Traynor, B. J., Troncoso, J., Turner, J. A., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., Van Der Brug, M., Van Der Lugt, A., Van Der Wee, N. J. A., Van Duijn, C. M., Van Haren, N. E. M., Van ′t Ent, D., Van Tol, M., Vardarajan, B. N., Veltman, D. J., Vernooij, M. W., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, H. R., Zonderman, A. B., Deary, I. J., Decarli, C., Schmidt, H., Martin, N. G., De Craen, A. J. M., Wright, M. J., Launer, L. J., Schumann, G., Fornage, M., Franke, B., Debette, S., Medland, S. E., Ikram, M. A. & Thompson, P. M., 2016, In : Nature Neuroscience. 19, 12, p. 1569-1582

    Research output: Contribution to journalArticle

  29. 2015
  30. Longitudinal Protein Changes in Blood Plasma Associated with the Rate of Cognitive Decline in Alzheimer's Disease

    Sattlecker, M., Khondoker, M., Proitsi, P., Williams, S., Soininen, H., K??oszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S. & Dobson, R. J., 23 Nov 2015, In : JOURNAL OF ALZHEIMERS DISEASE. 49, 4, p. 1105-1114 10 p.

    Research output: Contribution to journalArticle

  31. A Subset of Cerebrospinal Fluid Proteins from a Multi-Analyte Panel Associated with Brain Atrophy, Disease Classification and Prediction in Alzheimer's Disease

    Khan, W., Aguilar, C., Kiddle, S. J., Doyle, O., Thambisetty, M., Muehlboeck, S., Sattlecker, M., Newhouse, S., Lovestone, S., Dobson, R., Giampietro, V., Westman, E., Simmons, A. & Alzheimer’s Disease Neuroimaging Initiative, 18 Aug 2015, In : PLoS ONE. 10, 8, 16 p., e0134368.

    Research output: Contribution to journalArticle

  32. Tract based spatial statistic reveals no differences in white matter microstructural organization between carriers and non-carriers of the APOE ε4 and ε2 alleles in young healthy adolescents

    Dell'Acqua, F., Khan, W., Gottlieb, N., Giampietro, V., Ginestet, C., Bouls, D., Newhouse, S., Dobson, R., Banaschewski, T., Barker, G. J., Bokde, A. L. W., Büchel, C., Conrod, P., Flor, H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Lemaítre, H., Nees, F. & 10 othersPaus, T., Pausova, Z., Rietschel, M., Smolka, M. N., Ströhle, A., Gallinat, J., Westman, E., Schumann, G., Lovestone, S. & Simmons, A., 11 Aug 2015, In : JOURNAL OF ALZHEIMERS DISEASE. 47, 4, p. 977-984 8 p.

    Research output: Contribution to journalArticle

  33. No Evidence to Suggest that the Use of Acetylcholinesterase Inhibitors Confounds the Results of Two Blood-Based Biomarker Studies in Alzheimer's Disease

    Chiam, J. T. W., Lunnon, K., Voyle, N., Proitsi, P., Coppola, G., Geschwind, D., Nelson, S., Johnston, C., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Hodges, A., Lovestone, S., Newhouse, S., Dobson, R. J. B., Kiddle, S. J. & Sattlecker, M., 3 Aug 2015, In : JOURNAL OF ALZHEIMERS DISEASE. 47, 3, p. 741-750 10 p.

    Research output: Contribution to journalArticle

  34. Blood Protein Markers of Neocortical Amyloid-β Burden: A Candidate Study Using SOMAscan Technology.

    Voyle, N., Baker, D., Burnham, S. C., Covin, A., Zhang, Z., Sangurdekar, D. P., Tan, H. CA., Bazenet, C., Lovestone, S., Kiddle, S. & Dobson, R. J. B., 26 Jun 2015, In : JOURNAL OF ALZHEIMERS DISEASE. 46, 4, p. 947-961 15 p.

    Research output: Contribution to journalArticle

  35. Convergent genetic and expression data implicate immunity in Alzheimer's disease

    International Genomics of Alzheimer's Disease Consortium (IGAP)†, , Jun 2015, In : Alzheimer's & Dementia. 11, 6, p. 658-671

    Research output: Contribution to journalArticle

  36. Quantitative Interaction Proteomics of Neurodegenerative Disease Proteins

    the Genetic and Environmental Risk for Alzheimer’s Disease (GERAD1) Consortium, 19 May 2015, In : Cell Reports. 11, 7, p. 1134-1146 13 p.

    Research output: Contribution to journalArticle

  37. Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research

    O'Bryant, S. E., Gupta, V., Henriksen, K., Edwards, M., Jeromin, A., Lista, S., Bazenet, C., Soares, H., Lovestone, S., Hampel, H., Montine, T., Blennow, K., Foroud, T., Carrillo, M., Graff-Radford, N., Laske, C., Breteler, M., Shaw, L., Trojanowski, J. Q., Schupf, N. & 8 othersRissman, R. A., Fagan, A. M., Oberoi, P., Umek, R., Weiner, M. W., Grammas, P., Posner, H. & Martins, R., 1 May 2015, In : Alzheimer's & Dementia. 11, 5, p. 549-560 12 p.

    Research output: Contribution to journalArticle

  38. Common genetic variants influence human subcortical brain structures

    Hibar, D. P., Stein, J. L., Renteria, M. E., Arias-Vasquez, A., Desrivières, S., Jahanshad, N., Toro, R., Wittfeld, K., Abramovic, L., Andersson, M., Aribisala, B. S., Armstrong, N. J., Bernard, M., Bohlken, M. M., Boks, M. P., Bralten, J., Brown, A. A., Mallar Chakravarty, M., Chen, Q., Ching, C. R. K. & 31 othersCuellar-Partida, G., den Braber, A., Giddaluru, S., Goldman, A. L., Grimm, O., Guadalupe, T., Hass, J., Woldehawariat, G., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Macare, C., Ramasamy, A., Walton, E., Johnson, R., Perez-Iglesias, R., Schofield, P. R., Williams, R. W., Davies, G. E., Fisher, S. E., Lovestone, S., McDonald, C., Simmons, A., Weale, M. E., Schumann, G. & The Alzheimer’s Disease Neuroimaging Initiative, 9 Apr 2015, In : NATURE. 520, 7546, p. 224-+ 21 p.

    Research output: Contribution to journalArticle

  39. Blood protein predictors of brain amyloid for enrichment in clinical trials?

    Ashton, N., Kiddle, S., Graf, J., Ward, M., Baird, A., Hye, A., Westwood, S., Wong, K. V., Dobson, R., Rabinovici, G., Miller, B., Rosen, H., Torres, A., Zhang, Z., Thurfjell, L., Covin, A., Hehir, C., Baker, D., Bazenet, C. & Lovestone, S., 29 Mar 2015, In : Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 1, 1, p. 48-60 13 p.

    Research output: Contribution to journalArticle

  40. Linking Genetics of Brain Changes to Alzheimer's Disease: Sparse Whole Genome Association Scan of Regional MRI Volumes in the ADNI and AddNeuroMed Cohorts

    Khondoker, M., Newhouse, S., Westman, E., Muehlboeck, J-S., Mecocci, P., Vellas, B., Tsolaki, M., Kłoszewska, I., Soininen, H., Lovestone, S., Dobson, R. & Simmons, A., 2015, In : Journal of Alzheimer's disease : JAD. 45, 3, p. 851-864 14 p.

    Research output: Contribution to journalArticle

  41. Practical cut-offs for visual rating scales of medial temporal, frontal and posterior atrophy in Alzheimer's disease and mild cognitive impairment

    Ferreira, D., Cavallin, L., Larsson, E-M., Muehlboeck, J-S., Mecocci, P., Vellas, B., Tsolaki, M., Kłoszewska, I., Soininen, H., Lovestone, S., Simmons, A., Wahlund, L-O., Westman, E. & The AddNeuroMed consortium, the Alzheimer's Disease Neuroimaging, Initiative, 2015, In : Journal of Internal Medicine. 14 p.

    Research output: Contribution to journalArticle

  42. Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage

    Vos, S. J. B., Verhey, F., Frölich, L., Kornhuber, J., Wiltfang, J., Maier, W., Peters, O., Rüther, E., Nobili, F., Morbelli, S., Frisoni, G. B., Drzezga, A., Didic, M., van Berckel, B. N. M., Simmons, A., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B. & 20 othersLovestone, S., Muscio, C., Herukka, S-K., Salmon, E., Bastin, C., Wallin, A., Nordlund, A., de Mendonça, A., Silva, D., Santana, I., Lemos, R., Engelborghs, S., Van der Mussele, S., Freund-Levi, Y., Wallin, Å. K., Hampel, H., van der Flier, W., Scheltens, P., Visser, P. J. & The Alzheimer’s Disease Neuroimaging Initiative, 2015, In : Brain. 12 p.

    Research output: Contribution to journalArticle

  43. Protective variant for hippocampal atrophy identified by whole exome sequencing

    Nho, K., Kim, S., Risacher, S. L., Shen, L., Corneveaux, J. J., Swaminathan, S., Lin, H., Ramanan, V. K., Liu, Y., Foroud, T. M., Inlow, M. H., Siniard, A. L., Reiman, R. A., Aisen, P. S., Petersen, R. C., Green, R. C., Jack, C. R., Weiner, M. W., Baldwin, C. T., Lunetta, K. L. & 15 othersFarrer, L. A., Furney, S. J., Lovestone, S., Simmons, A., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Soininen, H., McDonald, B. C., Farlow, M. R., Ghetti, B., Huentelman, M. J., Saykin, A. J. & for the Indiana Memory, Aging Study, 2015, In : Annals of Neurology.

    Research output: Contribution to journalArticle

  44. 2014
  45. Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease

    Proitsi, P., Lupton, M. K., Velayudhan, L., Hunter, G., Newhouse, S., Lin, K., Fogh, I., Tsolaki, M., Daniilidou, M., Pritchard, M., Craig, D., Todd, S., Johnston, J. A., McGuinness, B., Kloszewska, I., Soininen, H., Mecocci, P., Vellas, B., Passmore, P. A., Sims, R. & 7 othersWilliams, J., Brayne, C., Stewart, R., Sham, P., Lovestone, S., Powell, J. F. & Alzheimer's Disease Neuroimaging Initiative, Dec 2014, In : Neurobiology of Aging. 35, 12, p. 2883.e3-2883.e10 8 p., 2883.

    Research output: Contribution to journalArticle

  46. Plasma proteins predict conversion to dementia from prodromal disease

    Hye, A., Riddoch-Contreras, J., Baird, A. L., Ashton, N., Bazenet, C., Leung, R., Westman, E., Simmons, A., Dobson, R., Sattlecker, M., Lupton, M., Lunnon, K., Keohane, A., Ward, M., Pike, I., Zucht, H. D., Pepin, D., Zheng, W., Tunnicliffe, A., Richardson, J. & 7 othersGauthier, S., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B. & Lovestone, S., 1 Nov 2014, In : Alzheimer's & dementia : the journal of the Alzheimer's Association. 10, 6, p. 799–807.e2 11 p.

    Research output: Contribution to journalArticle

  47. Genetic Predisposition to Increased Blood Cholesterol and Triglyceride Lipid Levels and Risk of Alzheimer Disease: A Mendelian Randomization Analysis

    Proitsi, P., Lupton, M. K., Velayudhan, L., Newhouse, S., Fogh, I., Tsolaki, M., Daniilidou, M., Pritchard, M., Kloszewska, I., Soininen, H., Mecocci, P., Vellas, B., Williams, J., Harold, D., Sims, R., Gerrish, A., Chapman, J., Escott-Price, V., Abraham, R., Hollingworth, P. & 74 othersHamshere, M., Singh Pahwa, J., Dowzell, K., Williams, A., Jones, N., Thomas, C., Stretton, A., Morgan, A., Williams, K., Lovestone, S., Powell, J. F., Proitsi, P., Lupton, M. K., Brayne, C., Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Morgan, K., Brown, K., Passmore, P., Craig, D., Mcguinness, B., Johnston, J. A., Todd, S., Holmes, C., Mann, D., Smith, A. D., Love, S., Kehoe, P. G., Hardy, J., Guerreiro, R., Singleton, A., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Heun, R., Schürmann, B., Ramirez, A., Becker, T., Herold, C., Lacour, A., Drichel, D., Van Den Bussche, H., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Frölich, L., Hampel, H., Hüll, M., Rujescu, D., Goate, A., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., Mcquillin, A., Gwilliam, R., Deloukas, P., Nöthen, M. M., Holmans, P., O'donovan, M., Owen, M. J., Williams, J., Stewart, R. & Sham, P., 16 Sep 2014, In : PLoS Medicine. 11, 9

    Research output: Contribution to journalArticle

  48. Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease

    Lunnon, K., Smith, R., Hannon, E., De Jager, P. L., Srivastava, G., Volta, M., Troakes, C., Al-Sarraj, S., Burrage, J., Macdonald, R., Condliffe, D., Harries, L. W., Katsel, P., Haroutunian, V., Kaminsky, Z., Joachim, C., Powell, J., Lovestone, S., Bennett, D. A., Schalkwyk, L. C. & 1 othersMill, J., Sep 2014, In : Nature Neuroscience. 17, 9, p. 1164-1170 7 p.

    Research output: Contribution to journalArticle

  49. Circulating Proteomic Signatures of Chronological Age

    Menni, C., Kiddle, S. J., Mangino, M., Viñuela, A., Psatha, M., Steves, C., Sattlecker, M., Buil, A., Newhouse, S., Nelson, S., Williams, S., Voyle, N., Soininen, H., Kloszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Lovestone, S., Spector, T. D., Dobson, R. & 1 othersValdes, A. M., 14 Aug 2014, In : The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 70, 7, p. 809-816 8 p.

    Research output: Contribution to journalArticle

  50. Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain

    Condliffe, D., Wong, A., Troakes, C., Proitsi, P., Patel, Y., Chouliaras, L., Fernandes, C., Cooper, J., Lovestone, S., Schalkwyk, L., Mill, J. & Lunnon, K., Aug 2014, In : Neurobiology of Aging. 35, 8, p. 1850-1854 5 p.

    Research output: Contribution to journalArticle

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