King's College London

Research portal

Research Outputs

  1. 2020
  2. Westwood, S, Baird, AL, Anand, SN, Nevado-Holgado, AJ, Kormilitzin, A, Shi, L, Hye, A, Ashton, NJ, Morgan, AR, Bos, I, Vos, SJB, Baker, S, Buckley, NJ, Ten Kate, M, Scheltens, P, Teunissen, CE, Vandenberghe, R, Gabel, S, Meersmans, K, Engelborghs, S, De Roeck, EE, Sleegers, K, Frisoni, GB, Blin, O, Richardson, JC, Bordet, R, Molinuevo, JL, Rami, L, Wallin, A, Kettunen, P, Tsolaki, M, Verhey, F, Lléo, A, Sala, I, Popp, J, Peyratout, G, Martinez-Lage, P, Tainta, M, Johannsen, P, Freund-Levi, Y, Frölich, L, Dobricic, V, Legido-Quigley, C, Bertram, L, Barkhof, F, Zetterberg, H, Morgan, BP, Streffer, J, Visser, PJ & Lovestone, S 2020, 'Validation of plasma proteomic biomarkers relating to brain amyloid burden in the EMIF-Alzheimer's disease multimodal biomarker discovery cohort', Journal of Alzheimer's Disease, vol. 74, no. 1, pp. 213-225. https://doi.org/10.3233/JAD-190434
  3. Newby, D, Prieto-Alhambra, D, Duarte-Salles, T, Ansell, D, Pedersen, L, Van Der Lei, J, Mosseveld, M, Rijnbeek, P, James, G, Alexander, M, Egger, P, Podhorna, J, Stewart, R, Perera, G, Avillach, P, Grosdidier, S, Lovestone, S & Nevado-Holgado, AJ 2020, 'Methotrexate and relative risk of dementia amongst patients with rheumatoid arthritis: A multi-national multi-database case-control study', Alzheimer's Research and Therapy, vol. 12, no. 1, 38. https://doi.org/10.1186/s13195-020-00606-5
  4. 2019
  5. Bos, I, Vos, S, Verhey, F, Scheltens, P, Teunissen, C, Engelborghs, S, Sleegers, K, Frisoni, G, Blin, O, Richardson, JC, Bordet, R, Tsolaki, M, Popp, J, Peyratout, G, Martinez-Lage, P, Tainta, M, Lleó, A, Johannsen, P, Freund-Levi, Y, Frölich, L, Vandenberghe, R, Westwood, S, Dobricic, V, Barkhof, F, Legido-Quigley, C, Bertram, L, Lovestone, S, Streffer, J, Andreasson, U, Blennow, K, Zetterberg, H & Visser, PJ 2019, 'Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum', Alzheimer's and Dementia, vol. 15, no. 5, pp. 644-654. https://doi.org/10.1016/j.jalz.2019.01.004
  6. Stamate, D, Kim, M, Proitsi, P, Westwood, S, Baird, A, Nevado-Holgado, A, Hye, A, Bos, I, Vos, SJB, Vandenberghe, R, Teunissen, CE, Kate, MT, Scheltens, P, Gabel, S, Meersmans, K, Blin, O, Richardson, J, De Roeck, E, Engelborghs, S, Sleegers, K, Bordet, R, Ramit, L, Kettunen, P, Tsolaki, M, Verhey, F, Alcolea, D, Lléo, A, Peyratout, G, Tainta, M, Johannsen, P, Freund-Levi, Y, Frölich, L, Dobricic, V, Frisoni, GB, Molinuevo, JL, Wallin, A, Popp, J, Martinez-Lage, P, Bertram, L, Blennow, K, Zetterberg, H, Streffer, J, Visser, PJ, Lovestone, S & Legido-Quigley, C 2019, 'A metabolite-based machine learning approach to diagnose Alzheimer-type dementia in blood: Results from the European Medical Information Framework for Alzheimer disease biomarker discovery cohort', Alzheimer's and Dementia: Translational Research and Clinical Interventions, vol. 5, pp. 933-938. https://doi.org/10.1016/j.trci.2019.11.001
  7. 2018
  8. Mårtensson, G, Pereira, JB, Mecocci, P, Vellas, B, Tsolaki, M, Kłoszewska, I, Soininen, H, Lovestone, S, Simmons, A, Volpe, G & Westman, E 2018, 'Stability of graph theoretical measures in structural brain networks in Alzheimer’s disease', Scientific Reports, vol. 8, no. 1, 11592. https://doi.org/10.1038/s41598-018-29927-0
  9. Ten Kate, M, Redolfi, A, Peira, E, Bos, I, Vos, SJ, Vandenberghe, R, Gabel, S, Schaeverbeke, J, Scheltens, P, Blin, O, Richardson, JC, Bordet, R, Wallin, A, Eckerstrom, C, Molinuevo, JL, Engelborghs, S, Van Broeckhoven, C, Martinez-Lage, P, Popp, J, Tsolaki, M, Verhey, FRJ, Baird, AL, Legido-Quigley, C, Bertram, L, Dobricic, V, Zetterberg, H, Lovestone, S, Streffer, J, Bianchetti, S, Novak, GP, Revillard, J, Gordon, MF, Xie, Z, Wottschel, V, Frisoni, G, Visser, PJ & Barkhof, F 2018, 'MRI predictors of amyloid pathology: Results from the EMIF-AD Multimodal Biomarker Discovery study', Alzheimer's Research and Therapy, vol. 10, no. 1, 100. https://doi.org/10.1186/s13195-018-0428-1
  10. Poulakis, K, Pereira, JB, Mecocci, P, Vellas, B, Tsolaki, M, Kłoszewska, I, Soininen, H, Lovestone, S, Simmons, A, Wahlund, L-O & Westman, E 2018, 'Heterogeneous patterns of brain atrophy in Alzheimer's disease', Neurobiology of Aging. https://doi.org/10.1016/j.neurobiolaging.2018.01.009
  11. 2017
  12. Horgusluoglu-Moloch, E, Nho, K, Risacher, SL, Kim, S, Foroud, T, Shaw, LM, Trojanowski, JQ, Aisen, PS, Petersen, RC, Jack, CR, Lovestone, S, Simmons, A, Weiner, MW & Saykin, AJ 2017, 'Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease', Neurobiology of Aging, vol. 60, pp. 92-103. https://doi.org/10.1016/j.neurobiolaging.2017.08.010
  13. Westwood, S, Baird, AL, Hye, A, Bos, I, Vos, SJB, Vandenberghe, R, Scheltens, P, Engelborghs, S, Frisoni, GB, Molinuevo, JL, Wallin, A, Lleó, A, Popp, J, Martinez-Lage, P, Snowden, SG, Legido-Quigley, C, Bertram, L, Barkhof, F, Zetterberg, H, Streffer, J, Visser, PJ & Lovestone, S 2017, 'DISCOVERY, REPLICATION AND EXTENSION STUDY OF PLASMA PROTEOMIC BIOMARKERS RELATING TO BRAIN AMYLOID BURDEN (CSF Aβ OR AMYLOID-PET) IN THE EMIF-AD BIOMARKER DISCOVERY COHORT: 2017 Abstract Supplement', Alzheimer's & Dementia, vol. 13, no. 7, Supplement, pp. P361-P362. https://doi.org/10.1016/j.jalz.2017.06.305
  14. Koychev, IG, Gunn, RN, Firouzian, A, Lawson, J, Zamboni, G, Ridha, BH, Sahakian, B, Rowe, JB, Thomas, A, Rochester, L, Ffytche, D, Howard, RJ, Zetterberg, H, MacKay, C & Lovestone, S 2017, 'PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY: 2017 Abstract Supplement', Alzheimer's & Dementia, vol. 13, no. 7, Supplement, pp. P243. https://doi.org/10.1016/j.jalz.2017.06.094
  15. Koychev, IG, Gunn, RN, Firouzian, A, Lawson, J, Zamboni, G, Ridha, BH, Sahakian, B, Rowe, JB, Thomas, A, Rochester, L, Ffytche, D, Howard, RJ, Zetterberg, H, MacKay, C & Lovestone, S 2017, 'PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY: 2017 Abstract Supplement', Alzheimer's & Dementia, vol. 13, no. 7, Supplement, pp. P456-P457. https://doi.org/10.1016/j.jalz.2017.06.464
  16. Sellers, KJ, Elliott, C, Jackson, J, Ghosh, A, Ribe, E, Rojo-Sanchís, A, Jarosz-Griffiths, HH, Watson, IA, Xia, W, Semenov, M, Morin, P, Hooper, NM, Porter, R, Preston, J, Al-Shawi, R, Baillie, G, Lovestone, S, Cuadrado, A, Harte, M, Simons, P, Srivastava, DP & Killick, R 2017, 'Amyloid beta synaptotoxicity is Wnt–planar cell polarity dependent and blocked by fasudil', Alzheimer's & Dementia. https://doi.org/10.1016/j.jalz.2017.09.008
  17. Westwood, S, Hye, A, Lleó, A, Nevado-Holgado, AJ, Baird, AL, Wallin, A, Leslie, A, Jimenez, B, Liu, BY, Legido-Quigley, C, Dima, D, Ruvolo, D, Holmes, E, D'Hondt, E, Westman, E, Barkhof, F, Frisoni, GB, Zetterberg, H, Bos, I, Pearce, J, Streffer, J, Molinuevo, JL, Popp, J, Bertram, L, Whiley, L, Maslen, L, Gomez-Romero, M, David, M, Lewis, M, Kurbatova, N, Ashton, NJ, Voyle, N, Kowalczyk, O, Martinez-Lage, P, Proitsi, P, Scheltens, P, Visser, PJ, Dobson, RJB, Vandenberghe, R, Engelborghs, S, Vos, SJB, Snowden, SG, Athersuch, T, Ashby, T, Kimhofer, T, Verachtert, W & Lovestone, S 2017, 'DISCOVERY AND VALIDATION OF MULTIMODAL BIOMARKER SIGNATURES RELATING TO ALZHEIMER'S DISEASE PATHOLOGY AND PROGRESSION: 2017 Abstract Supplement', Alzheimer's & Dementia, vol. 13, no. 7, Supplement, pp. P174-P175. https://doi.org/10.1016/j.jalz.2017.07.016
  18. Khan, W, Giampietro, V, Banaschewski, T, Barker, GJ, Bokde, ALW, Büchel, C, Conrod, P, Flor, H, Frouin, V, Garavan, H, Gowland, P, Heinz, A, Ittermann, B, Lemaître, H, Nees, F, Paus, T, Pausova, Z, Rietschel, M, Smolka, MN, Ströhle, A, Gallinat, J, Vellas, B, Soininen, H, Kloszewska, I, Tsolaki, M, Mecocci, P, Spenger, C, Villemagne, VL, Masters, CL, Muehlboeck, JS, Bäckman, L, Fratiglioni, L, Kalpouzos, G, Wahlund, LO, Schumann, G, Lovestone, S, Williams, SCR, Westman, E & Simmons, A 2017, 'A Multi-Cohort Study of ApoE ϵ 4 and Amyloid-β Effects on the Hippocampus in Alzheimer's Disease', JOURNAL OF ALZHEIMERS DISEASE, vol. 56, no. 3, pp. 1159-1174. https://doi.org/10.3233/JAD-161097
  19. Hibar, DP, Adams, HHH, Jahanshad, N, Chauhan, G, Stein, JL, Hofer, E, Renteria, ME, Bis, JC, Arias-Vasquez, A, Ikram, MK, Desrivières, S, Vernooij, MW, Abramovic, L, Alhusaini, S, Amin, N, Andersson, M, Arfanakis, K, Aribisala, BS, Armstrong, NJ, Athanasiu, L, Axelsson, T, Beecham, AH, Beiser, A, Bernard, M, Blanton, SH, Bohlken, MM, Boks, MP, Bralten, J, Brickman, AM, Carmichael, O, Chakravarty, MM, Chen, Q, Ching, CRK, Chouraki, V, Cuellar-Partida, G, Crivello, F, Den Braber, A, Doan, NT, Ehrlich, S, Giddaluru, S, Goldman, AL, Gottesman, RF, Grimm, O, Griswold, ME, Guadalupe, T, Gutman, BA, Hass, J, Haukvik, UK, Hoehn, D, Holmes, AJ, Hoogman, M, Janowitz, D, Jia, T, Jørgensen, KN, Karbalai, N, Kasperaviciute, D, Kim, S, Klein, M, Kraemer, B, Lee, PH, Liewald, DCM, Lopez, LM, Luciano, M, Macare, C, Marquand, AF, Matarin, M, Mather, KA, Mattheisen, M, McKay, DR, Milaneschi, Y, Muñoz Maniega, S, Nho, K, Nugent, AC, Nyquist, P, Loohuis, LMO, Oosterlaan, J, Papmeyer, M, Pirpamer, L, Pütz, B, Ramasamy, A, Richards, JS, Risacher, SL, Roiz-Santiañez, R, Rommelse, N, Ropele, S, Rose, EJ, Royle, NA, Rundek, T, Sämann, PG, Saremi, A, Satizabal, CL, Schmaal, L, Schork, AJ, Shen, L, Shin, J, Shumskaya, E, Smith, AV, Sprooten, E, Strike, LT, Teumer, A, Tordesillas-Gutierrez, D, Toro, R, Trabzuni, D, Trompet, S, Vaidya, D, Van der Grond, J, Van der Lee, SJ, Van der Meer, D, Van Donkelaar, MMJ, Van Eijk, KR, Van Erp, TGM, Van Rooij, D, Walton, E, Westlye, LT, Whelan, CD, Windham, BG, Winkler, AM, Wittfeld, K, Woldehawariat, G, Wolf, C, Wolfers, T, Yanek, LR, Yang, J, Zijdenbos, A, Zwiers, MP, Agartz, I, Almasy, L, Ames, D, Amouyel, P, Andreassen, OA, Arepalli, S, Assareh, AA, Barral, S, Bastin, ME, Becker, DM, Becker, JT, Bennett, DA, Blangero, J, van Bokhoven, H, Boomsma, DI, Brodaty, H, Brouwer, RM, Brunner, HG, Buckner, RL, Buitelaar, JK, Bulayeva, KB, Cahn, W, Calhoun, VD, Cannon, DM, Cavalleri, GL, Cheng, C-Y, Cichon, S, Cookson, MR, Corvin, A, Crespo-Facorro, B, Curran, JE, Czisch, M, Dale, AM, Davies, GE, De Craen, AJM, De Geus, EJC, De Jager, PL, De Zubicaray, GI, Deary, IJ, Debette, S, DeCarli, C, Delanty, N, Depondt, C, DeStefano, A, Dillman, A, Djurovic, S, Donohoe, G, Drevets, WC, Duggirala, R, Dyer, TD, Enzinger, C, Erk, S, Espeseth, T, Fedko, IO, Fernández, G, Ferrucci, L, Fisher, SE, Fleischman, DA, Ford, I, Fornage, M, Foroud, TM, Fox, PT, Francks, C, Fukunaga, M, Gibbs, JR, Glahn, DC, Gollub, RL, Göring, HHH, Green, RC, Gruber, O, Gudnason, V, Guelfi, S, Håberg, AK, Hansell, NK, Hardy, J, Hartman, CA, Hashimoto, R, Hegenscheid, K, Heinz, A, Le Hellard, S, Hernandez, DG, Heslenfeld, DJ, Ho, B-C, Hoekstra, PJ, Hoffmann, W, Hofman, A, Holsboer, F, Homuth, G, Hosten, N, Hottenga, J-J, Huentelman, M, Pol, HEH, Ikeda, M, Jack, CR, Jenkinson, M, Johnson, R, Jönsson, EG, Jukema, JW, Kahn, RS, Kanai, R, Kloszewska, I, Knopman, DS, Kochunov, P, Kwok, JB, Lawrie, SM, Lemaître, H, Liu, X, Longo, DL, Lopez, OL, Lovestone, S, Martinez, O, Martinot, J-L, Mattay, VS, McDonald, C, McIntosh, AM, McMahon, FJ, McMahon, KL, Mecocci, P, Melle, I, Meyer-Lindenberg, A, Mohnke, S, Montgomery, GW, Morris, DW, Mosley, TH, Mühleisen, TW, Müller-Myhsok, B, Nalls, MA, Nauck, M, Nichols, TE, Niessen, WJ, Nöthen, MM, Nyberg, L, Ohi, K, Olvera, RL, Ophoff, RA, Pandolfo, M, Paus, T, Pausova, Z, Penninx, BWJH, Pike, GB, Potkin, SG, Psaty, BM, Reppermund, S, Rietschel, M, Roffman, JL, Romanczuk-Seiferth, N, Rotter, JI, Ryten, M, Sacco, RL, Sachdev, PS, Saykin, AJ, Schmidt, R, Schmidt, H, Schofield, PR, Sigursson, S, Simmons, A, Singleton, A, Sisodiya, SM, Smith, C, Smoller, JW, Soininen, H, Steen, VM, Stott, DJ, Sussmann, JE, Thalamuthu, A, Toga, AW, Traynor, BJ, Troncoso, J, Tsolaki, M, Tzourio, C, Uitterlinden, AG, Hernández, MCV, Van der Brug, M, van der Lugt, A, van der Wee, NJA, Van Haren, NEM, van 't Ent, D, Van Tol, M-J, Vardarajan, BN, Vellas, B, Veltman, DJ, Völzke, H, Walter, H, Wardlaw, JM, Wassink, TH, Weale, ME, Weinberger, DR, Weiner, MW, Wen, W, Westman, E, White, T, Wong, TY, Wright, CB, Zielke, RH, Zonderman, AB, Martin, NG, Van Duijn, CM, Wright, MJ, Longstreth, WT, Schumann, G, Grabe, HJ, Franke, B, Launer, LJ, Medland, SE, Seshadri, S, Thompson, PM & Ikram, MA 2017, 'Novel genetic loci associated with hippocampal volume', Nature Communications, vol. 8, pp. 13624. https://doi.org/10.1038/ncomms13624
  20. 2016
  21. Lovestone, S, Rossor, M, Gallacher, J, Ritchie, C, Burn, D, Hyslop, PSG, Mackay, C, Matthews, PM, Ballard, C & Georges, J 2016, 'Better together for better dementia research and care', The Lancet Psychiatry. https://doi.org/10.1016/S2215-0366(16)30090-6
  22. Traylor, M, Adib-samii, P, Harold, D, Dichgans, M, Williams, J, Lewis, CM, Markus, HS, METASTROKE and International Genomics of Alzheimer's Project (IGAP) investigators, Lovestone, SH & Proitsi, P 2016, 'Shared genetic contribution to ischemic stroke and Alzheimer's disease: Ischemic Stroke and Alzheimer's Disease', Annals of Neurology, vol. 79, no. 5, pp. 739-747. https://doi.org/10.1002/ana.24621
  23. Allen, GI, Amoroso, N, Anghel, C, Balagurusamy, V, Bare, CJ, Beaton, D, Bellotti, R, Bennett, DA, Boehme, KL, Boutros, PC, Caberlotto, L, Caloian, C, Campbell, F, Chaibub Neto, E, Chang, Y-C, Chen, B, Chen, C-Y, Chien, T-Y, Clark, T, Das, S, Davatzikos, C, Deng, J, Dillenberger, D, Dobson, RJB, Dong, Q, Doshi, J, Duma, D, Errico, R, Erus, G, Everett, E, Fardo, DW, Friend, SH, Fröhlich, H, Gan, J, St George-Hyslop, P, Ghosh, SS, Glaab, E, Green, RC, Guan, Y, Hong, M-Y, Huang, C, Hwang, J, Ibrahim, J, Inglese, P, Iyappan, A, Jiang, Q, Katsumata, Y, Kauwe, JSK, Klein, A, Kong, D, Krause, R, Lalonde, E, Lauria, M, Lee, E, Lin, X, Liu, Z, Livingstone, J, Logsdon, BA, Lovestone, S, Ma, T, Malhotra, A, Mangravite, LM, Maxwell, TJ, Merrill, E, Nagorski, J, Namasivayam, A, Narayan, M, Naz, M, Newhouse, SJ, Norman, TC, Nurtdinov, RN, Oyang, Y-J, Pawitan, Y, Peng, S, Peters, MA, Piccolo, SR, Praveen, P, Priami, C, Sabelnykova, VY, Senger, P, Shen, X, Simmons, A, Sotiras, A, Stolovitzky, G, Tangaro, S, Tateo, A, Tung, Y-A, Tustison, NJ, Varol, E, Vradenburg, G, Weiner, MW, Xiao, G, Xie, L, Xie, Y, Xu, J, Yang, H, Zhan, X, Zhou, Y, Zhu, F, Zhu, H & Zhu, S 2016, 'Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease', Alzheimer's & Dementia, vol. 12, no. 6, pp. 645-653. https://doi.org/10.1016/j.jalz.2016.02.006
  24. Lupton, MK, Strike, L, Hansell, NK, Wen, W, Mather, KA, Armstrong, NJ, Thalamuthu, A, McMahon, KL, de Zubicaray, GI, Assareh, AA, Simmons, A, Proitsi, P, Powell, JF, Montgomery, GW, Hibar, DP, Westman, E, Tsolaki, M, Kloszewska, I, Soininen, H, Mecocci, P, Velas, B, Lovestone, S, Brodaty, H, Ames, D, Trollor, JN, Martin, NG, Thompson, PM, Sachdev, PS & Wright, MJ 2016, 'The effect of increased genetic risk for Alzheimer's disease on hippocampal and amygdala volume', Neurobiology of Aging, vol. 40, pp. 68-77. https://doi.org/10.1016/j.neurobiolaging.2015.12.023
  25. Falahati, F, Ferreira, D, Soininen, H, Mecocci, P, Vellas, B, Tsolaki, M, Kłoszewska, I, Lovestone, S, Eriksdotter, M, Wahlund, LO, Simmons, A & Westman, E 2016, 'The Effect of Age Correction on Multivariate Classification in Alzheimer’s Disease, with a Focus on the Characteristics of Incorrectly and Correctly Classified Subjects', Brain topography, vol. 29, no. 2, pp. 296-307. https://doi.org/10.1007/s10548-015-0455-1
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