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Research Outputs

  1. 2019
  2. Genome-wide survey of copy number variants finds MAPT duplications in progressive supranuclear palsy

    NNIPPS and BBBIPPS Study Groups, 6 May 2019, In : Movement Disorders.

    Research output: Contribution to journalArticle

  3. The contribution of cannabis use to variation in the incidence of psychotic disorder across Europe (EU-GEI): a multicentre case-control study

    EU-GEI WP2 Group, 1 May 2019, In : The Lancet Psychiatry. 6, 5, p. 427-436 10 p.

    Research output: Contribution to journalArticle

  4. Polygenic risk for circulating reproductive hormone levels and their influence on hippocampal volume and depression susceptibility

    Smeeth, D. M., Dima, D., Jones, L., Jones, I., Craddock, N., Owen, M. J., Rietschel, M., Maier, W., Korszun, A., Rice, J. P., Mors, O., Preisig, M., Uher, R., Lewis, C. M., Thuret, S. & Powell, T. R., 20 Apr 2019, In : Psychoneuroendocrinology. 106, p. 284-292 9 p.

    Research output: Contribution to journalArticle

  5. Genome-wide burden of rare short deletions is enriched in Major Depressive Disorder in four cohorts

    Zhang, X., Abdellaoui, A., Rucker, J., de Jong, S., Potash, J. B., Weissman, M. M., Shi, J., Knowles, J. A., Pato, C., Pato, M., Sobell, J., Smit, J. H., Hottenga, J. J., de Geus, E. J. C., Lewis, C. M., Buttenschøn, H. N., Craddock, N., Jones, I., Jones, L., McGuffin, P. & 13 othersMors, O., Owen, M. J., Preisig, M., Rietschel, M., Rice, J. P., Rivera, M., Uher, R., Gejman, P. V., Sanders, A. R., Boomsma, D., Penninx, B. W. J. H., Breen, G. & Levinson, D. F., 13 Mar 2019, In : Biological psychiatry.

    Research output: Contribution to journalArticle

  6. Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

    Howard, D. M., Adams, M. J., Clarke, T., Hafferty, J. D., Gibson, J., Shirali, M., Coleman, J. R. I., Hagenaars, S. P., Ward, J., Wigmore, E. M., Alloza, C., Shen, X., Barbu, M. C., Xu, E. Y., Whalley, H. C., Marioni, R. E., Porteous, D. J., Davies, G., Deary, I. J., Hemani, G. & 18 othersBerger, K., Teismann, H., Rawal, R., Arolt, V., Baune, B. T., Dannlowski, U., Domschke, K., Tian, C., Hinds, D. A., Trzaskowski, M., Byrne, E. M., Ripke, S., Smith, D. J., Sullivan, P. F., Wray, N. R., Breen, G., Lewis, C. M. & Mcintosh, A. M., Mar 2019, In : Nature Neuroscience. 22, 3, p. 343-352 10 p.

    Research output: Contribution to journalArticle

  7. Association of genetic variants in CHEK2 with oesophageal squamous cell carcinoma in the South African Black population

    Chen, W. C., Bye, H., Matejcic, M., Amar, A., Govender, D., Khew, Y. W., Beynon, V., Kerr, R., Singh, E., Prescott, N. J., Lewis, C. M., Babb de Villiers, C., Parker, M. I. & Mathew, C. G., 12 Feb 2019, In : Carcinogenesis.

    Research output: Contribution to journalArticle

  8. Quantifying between-cohort and between-sex genetic heterogeneity in major depressive disorder

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Feb 2019, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics.

    Research output: Contribution to journalArticle

  9. Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP

    Wigmore, E. M., Hafferty, J. D., Hall, L. S., Howard, D. M., Clarke, T-K., Fabbri, C., Lewis, C. M., Uher, R., Navrady, L. B., Adams, M. J., Zeng, Y., Campbell, A., Gibson, J., Thomson, P. A., Hayward, C., Smith, B. H., Hocking, L. J., Padmanabhan, S., Deary, I. J., Porteous, D. J. & 4 othersMors, O., Mattheisen, M., Nicodemus, K. K. & McIntosh, A. M., 31 Jan 2019, In : The pharmacogenomics journal.

    Research output: Contribution to journalArticle

  10. 2018
  11. Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

    Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Coleman, J. R. I., Eley, T. C., Gaspar, H. A., McGuffin, P., Mullins, N., O'Reilly, P. F., Lewis, C. M. & Breen, G., 20 Dec 2018, In : PLoS ONE. 13, 12, e0209160.

    Research output: Contribution to journalArticle

  12. Telomere length as a predictor of emotional processing in the brain

    Powell, T. R., De Jong, S., Breen, G., Lewis, C. M. & Dima, D., 4 Dec 2018, In : Human Brain Mapping.

    Research output: Contribution to journalArticle

  13. Genes associated with anhedonia: a new analysis in a large clinical trial (GENDEP)

    Ren, H., Fabbri, C., Uher, R., Rietschel, M., Mors, O., Henigsberg, N., Hauser, J., Zobel, A., Maier, W., Dernovsek, M. Z., Souery, D., Cattaneo, A., Breen, G., Craig, I. W., Farmer, A. E., McGuffin, P., Lewis, C. M. & Aitchison, K. J., 1 Dec 2018, In : Translational psychiatry. 8, 1, 150.

    Research output: Contribution to journalArticle

  14. Genome-wide association study of treatment-resistance in depression and meta-analysis of three independent samples

    Fabbri, C., Kasper, S., Kautzky, A., Bartova, L., Dold, M., Zohar, J., Souery, D., Montgomery, S., Albani, D., Raimondi, I., Dikeos, D., Rujescu, D., Uher, R., Lewis, C. M., Mendlewicz, J. & Serretti, A., 23 Nov 2018, In : British Journal of Psychiatry. 214, 1, p. 36-41

    Research output: Contribution to journalArticle

  15. Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders

    O'Brien, H. E., Hannon, E., Hill, M. J., Toste, C. C., Robertson, M. J., Morgan, J. E., McLaughlin, G., Lewis, C. M., Schalkwyk, L. C., Hall, L. S., Pardiñas, A. F., Owen, M. J., O'Donovan, M. C., Mill, J. & Bray, N. J., 12 Nov 2018, In : Genome Biology. 19, 1, 1 p.

    Research output: Contribution to journalArticle

  16. Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans

    Hanscombe, K. B., Morris, D. L., Noble, J. A., Dilthey, A. T., Tombleson, P., Kaufman, K. M., Comeau, M., Langefeld, C. D., Alarcon-Riquelme, M. E., Gaffney, P. M., Jacob, C. O., Sivils, K. L., Tsao, B. P., Alarcon, G. S., Brown, E. E., Croker, J., Edberg, J., Gilkeson, G., James, J. A., Kamen, D. L. & 16 othersKelly, J. A., McCune, J., Merrill, J. T., Petri, M., Ramsey-Goldman, R., Reveille, J. D., Salmon, J. E., Scofield, H., Utset, T., Wallace, D. J., Weisman, M. H., Kimberly, R. P., Harley, J. B., Lewis, C. M., Criswell, L. A. & Vyse, T. J., 1 Nov 2018, In : Human Molecular Genetics. 27, 21, p. 3813-3824 12 p., 27(21).

    Research output: Contribution to journalArticle

  17. Transdiagnostic dimensions of psychopathology at first episode psychosis: findings from the multinational EU-GEI study

    Quattrone, D., Di Forti, M., Gayer-Anderson, C., Ferraro, L., Jongsma, H. E., Tripoli, G., La Cascia, C., La Barbera, D., Tarricone, I., Berardi, D., EU-GEI WP2 Group, Szöke, A., Arango, C., Lasalvia, A., Tortelli, A., Llorca, P-M., de Haan, L., Velthorst, E., Bobes, J., Bernardo, M. & 18 othersSanjuán, J., Santos, J. L., Arrojo, M., Del-Ben, C. M., Menezes, P. R., Selten, J-P., Jones, P. B., Kirkbride, J. B., Richards, A. L., O'Donovan, M. C., Sham, P. C., Vassos, E., Rutten, B. P., van Os, J., Morgan, C., Lewis, C. M., Murray, R. M. & Reininghaus, U., 4 Oct 2018, In : Psychological Medicine. p. 1-14 14 p.

    Research output: Contribution to journalArticle

  18. Conference Report: Psychiatric Genomics Consortium Meeting: Pathways to Drugs, London, March 2017

    Gaspar, H. A., Collier, D. A., Geschwind, D. H., Lewis, C. M., Li, Q., Roth, B. L., Sullivan, P. F. & Breen, G., 15 Sep 2018, In : Biological psychiatry. 84, 6, p. e49-e50

    Research output: Contribution to journalArticle

  19. Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders

    Genetic Risk and Outcome of Psychosis (GROUP) consortium, Sep 2018, In : The British journal of psychiatry : the journal of mental science. 213, 3, p. 535-541 7 p.

    Research output: Contribution to journalArticle

  20. Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases

    Chen, J. A., Chen, Z., Won, H., Huang, A. Y., Lowe, J. K., Wojta, K., Yokoyama, J. S., Bensimon, G., Leigh, P. N., Payan, C., Shatunov, A., Jones, A. R., Lewis, C. M., Deloukas, P., Amouyel, P., Tzourio, C., Dartigues, J. F., Ludolph, A., Boxer, A. L., Bronstein, J. M. & 3 othersAl-Chalabi, A., Geschwind, D. H. & Coppola, G., 8 Aug 2018, In : Molecular Neurodegeneration. 13, 1, 41.

    Research output: Contribution to journalArticle

  21. Genetic disposition to inflammation and response to antidepressants in major depressive disorder

    Zwicker, A., Fabbri, C., Rietschel, M., Hauser, J., Mors, O., Maier, W., Zobel, A., Farmer, A., Aitchison, K. J., McGuffin, P., Lewis, C. M. & Uher, R., 7 Aug 2018, In : Journal of psychiatric research.

    Research output: Contribution to journalArticle

  22. Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies

    Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Lee, S-H., Newhouse, S., Patel, H., O'Donovan, M., Lewis, G., Jenkins, G., Weinshilboum, R. M., Farmer, A. & 7 othersAitchison, K. J., Craig, I., McGuffin, P., Schruers, K., Biernacka, J. M., Uher, R. & Lewis, C. M., 28 Jun 2018, In : European Neuropsychopharmacology.

    Research output: Contribution to journalArticle

  23. DNA methylation and inflammation marker profiles associated with a history of depression

    Crawford, B., Craig, Z., Mansell, G., White, I., Smith, A., Spaull, S., Imm, J., Hannon, E., Wood, A., Yaghootkar, H., Ji, Y., Mullins, N., Lewis, C. M., Mill, J. & Murphy, T. M., 22 May 2018, In : Human Molecular Genetics. 27, 16, p. 2840-2850 11 p.

    Research output: Contribution to journalArticle

  24. New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

    Fabbri, C., Tansey, K., Perlis, R., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Sang-Hyuk, L., Newhouse, S., Patel, H., Guipponi, M., Perroud, N., Bondolfi, G., O'Donovan, M., Lewis, G. & 8 othersBiernacka, J., Weinshilboum, R., Farmer, A., Aitchison, K., Craig, I., McGuffin, P., Uher, R. & Lewis, C., 22 May 2018, In : The pharmacogenomics journal. 18, p. 413-421

    Research output: Contribution to journalArticle

  25. Exome array analysis of adverse reactions to fluoropyrimidine-based therapy for gastrointestinal cancer

    Traylor, M., Walker, J. L., Corrigan, A. A., Hernandez, M. A., Newhouse, S. J., Folarin, A. A., Patel, H., Ross, P. J., Sanderson, J. D., Spicer, J., Prescott, N. J., Mathew, C. G., Marinaki, A. M. & Lewis, C. M., 1 May 2018, In : PLoS ONE. 13, 5, 11 p., e0188911.

    Research output: Contribution to journalArticle

  26. Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

    The Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S., Bækvad-hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-grauholm, J. & 32 othersCai, N., Castelao, E., Christensen, J. H., Clarke, T., Coleman, J. I. R., Colodro-conde, L., Couvy-duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Eley, T. C., Gaspar, H. A., Hansen, T. F., Li, Y., Mcguffin, P., Mill, J., Mullins, N., Purcell, S. M., Riley, B. P., Smith, D. J., Tansey, K. E., Traylor, M., Uher, R., Lewis, C. M., Breen, G. & O'Reilly, P. F., 1 May 2018, In : Nature Genetics. 50, 5, p. 668-681

    Research output: Contribution to journalArticle

  27. Antidepressant drug-specific prediction of depression treatment outcomes from genetic and clinical variables

    Iniesta, R., Hodgson, K., Stahl, D. R., Malki, K., Maier, W., Rietschel, M., Mors, O., Hauser, J., Henigsberg, N., Dernovšek, M. Z., Souery, D., Dobson, R. M., Aitchison, K. J., Farmer, A. E., McGuffin, P., Lewis, C. M. & Uher, R., 3 Apr 2018, In : Scientific Reports.

    Research output: Contribution to journalArticle

  28. Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

    Howard, D. M., Adams, M. J., Shirali, M., Clarke, T-K., Marioni, R. E., Davies, G., Coleman, J. R. I., Alloza, C., Shen, X., Barbu, M. C., Wigmore, E. M., Gibson, J., Hagenaars, S. P., Lewis, C. M., Ward, J., Smith, D. J., Sullivan, P. F., Haley, C. S., Breen, G., Deary, I. J. & 1 othersMcIntosh, A. M., 2018, In : Nature Communications. 9, 1, 1470.

    Research output: Contribution to journalArticle

  29. 2017
  30. Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations

    Milaneschi, Y., Lamers, F., Peyrot, W. J., Baune, B. T., Breen, G., Dehghan, A., Forstner, A. J., Grabe, H. J., Homuth, G., Kan, C., Lewis, C., Mullins, N., Nauck, M., Pistis, G., Preisig, M., Rivera, M., Rietschel, M., Streit, F., Strohmaier, J., Teumer, A. & 4 othersVan der Auwera, S., Wray, N. R., Boomsma, D. I. & Penninx, B. W. J. H., 1 Dec 2017, In : JAMA Psychiatry. 74, 12, p. 1214-1225 12 p.

    Research output: Contribution to journalArticle

  31. New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

    Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Sang-Hyuk, L., Newhouse, S., Patel, H., Guipponi, M., Perroud, N., Bondolfi, G., O'Donovan, M., Lewis, G. & 8 othersBiernacka, J. M., Weinshilboum, R. M., Farmer, A., Aitchison, K. J., Craig, I., McGuffin, P., Uher, R. & Lewis, C. M., 21 Nov 2017, In : The pharmacogenomics journal.

    Research output: Contribution to journalArticle

  32. Prospects for using risk scores in polygenic medicine

    Lewis, C. M. & Vassos, E., 13 Nov 2017, In : Genome medicine. 9, 1, 3 p., 96.

    Research output: Contribution to journalComment/debate

  33. Advancing psychiatric genetics through dissecting heterogeneity

    Hodgson, K., McGuffin, P. & Lewis, C. M., 1 Oct 2017, In : Human Molecular Genetics. 26, R2, p. R160-R165

    Research output: Contribution to journalReview article

  34. Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium

    Peyrot, W. J., Van der Auwera, S., Milaneschi, Y., Dolan, C. V., Madden, P. AF., Sullivan, P. F., Strohmaier, J., Ripke, S., Rietschel, M., Nivard, M. G., Mullins, N., Montgomery, G. W., Henders, A. K., Heat, A. C., Fisher, H. L., Dunn, E. C., Byrne, E. M., Air, T. A. & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 21 Sep 2017, In : Biological psychiatry.

    Research output: Contribution to journalArticle

  35. Interaction between childhood maltreatment on immunogenetic risk in depression: discovery and replication in clinical case-control samples

    Cohen-Woods, S., Fisher, H. L., Ahmetspahic, D., Douroudis, K., Stacey, D., Hosang, G. M., Korszun, A., Owen, M., Craddock, N., Arolt, V., Dannowski, U., Breen, G., Craig, I. W., Farmer, A., Baune, B. T., Lewis, C. M., Uher, R. & McGuffin, P., 1 Sep 2017, In : Brain, Behavior, and Immunity. 67, p. 203-210

    Research output: Contribution to journalArticle

  36. A polygenic risk score analysis of psychosis endophenotypes across brain functional, structural, and cognitive domains

    Ranlund, S., Calafato, S., Thygesen, J. H., Lin, K., Cahn, W., Crespo-Facorro, B., de Zwarte, S. M. C., Díez, Á., Di Forti, M., Iyegbe, C., Jablensky, A., Jones, R., Hall, M. H., Kahn, R., Kalaydjieva, L., Kravariti, E., Mcdonald, C., Mcintosh, A. M., Mcquillin, A., Picchioni, M. & 13 othersPrata, D. P., Rujescu, D., Schulze, K., Shaikh, M., Toulopoulou, T., van Haren, N., van Os, J., Vassos, E., Walshe, M., Lewis, C., Murray, R. M., Powell, J. & Bramon, E., 29 Aug 2017, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 177, 1, p. 21-34

    Research output: Contribution to journalArticle

  37. Interaction between the FTOgene, body mass index and depression: meta-analysis of 13701 individuals

    Rivera, M., Locke, A. E., Corre, T., Czamara, D., Wolf, C., Ching-Lopez, A., Milaneschi, Y., Kloiber, S., Cohen-Woods, S., Rucker, J., Aitchison, K. J., Bergmann, S., Boomsma, D. I., Craddock, N., Gill, M., Holsboer, F., Hottenga, J-J., Korszun, A., Kutalik, Z., Lucae, S. & 18 othersMaier, W., Mors, O., Müller-Myhsok, B., Owen, M. J., Penninx, B. W. J. H., Preisig, M., Rice, J., Rietschel, M., Tozzi, F., Uher, R., Vollenweider, P., Waeber, G., Willemsen, G., Craig, I. W., Farmer, A. E., Lewis, C. M., Breen, G. & McGuffin, P., 1 Aug 2017, In : British Journal of Psychiatry. 211, 2, p. 70-76 7 p.

    Research output: Contribution to journalArticle

  38. Validating a two-dimensional bipolar spectrum model integrating DSM-5's mixed features specifier for Major Depressive Disorder

    Ferentinos, P., Fountoulakis, K. N., Lewis, C. M., Porichi, E., Dikeos, D., Papageorgiou, C. & Douzenis, A., 1 Aug 2017, In : Comprehensive Psychiatry. 77, p. 89-99 11 p.

    Research output: Contribution to journalArticle

  39. Genetics of Depression: Progress at Last

    Mullins, N. & Lewis, C. M., Aug 2017, In : CURRENT PSYCHIATRY REPORTS. 19, 8, p. 1-7 43.

    Research output: Contribution to journalArticle

  40. Interaction between the FTO gene, body mass index and depression: meta-analysis of 13701 individuals

    Rivera, M., Locke, A. E., Corre, T., Czamara, D., Wolf, C., Ching-Lopez, A., Milaneschi, Y., Kloiber, S., Cohen-Woods, S., Rucker, J., Aitchison, K. J., Bergmann, S., Boomsma, D. I., Craddock, N., Gill, M., Holsboer, F., Hottenga, J-J., Korszun, A., Kutalik, Z., Lucae, S. & 18 othersMaier, W., Mors, O., Müller-Myhsok, B., Owen, M. J., Penninx, B. W. J. H., Preisig, M., Rice, J., Rietschel, M., Tozzi, F., Uher, R., Vollenweider, P., Waeber, G., Willemsen, G., Craig, I. W., Farmer, A. E., Lewis, C. M., Breen, G. & McGuffin, P., 22 Jun 2017, In : The British journal of psychiatry : the journal of mental science.

    Research output: Contribution to journalArticle

  41. Pharmacogenetic testing through the direct-to-consumer genetic testing company 23andMe

    Lu, M., Lewis, C. M. & Traylor, M., 19 Jun 2017, In : BMC GENOMICS. 1, 1

    Research output: Contribution to journalArticle

  42. Cost-effectiveness of pharmacogenetic-guided treatment: are we there yet?

    Verbelen, M., Weale, M. E. & Lewis, C. M., 13 Jun 2017, In : The pharmacogenomics journal. 17, 5, p. 395-402

    Research output: Contribution to journalArticle

  43. MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes

    Lopez, J. P., Fiori, L. M., Cruceanu, C., Lin, R., Labonte, B., Cates, H. M., Heller, E. A., Vialou, V., Ku, S. M., Gerald, C., Han, M-H., Foster, J., Frey, B. N., Soares, C. N., Müller, D. J., Farzan, F., Leri, F., MacQueen, G. M., Feilotter, H., Tyryshkin, K. & 16 othersEvans, K. R., Giacobbe, P., Blier, P., Lam, R. W., Milev, R., Parikh, S. V., Rotzinger, S., Strother, S. C., Lewis, C. M., Aitchison, K. J., Wittenberg, G. M., Mechawar, N., Nestler, E. J., Uher, R., Kennedy, S. H. & Turecki, G., 22 May 2017, In : Nature Communications. 8, 15497.

    Research output: Contribution to journalArticle

  44. Pharmacogenetics of antidepressant response: A polygenic approach

    Major Depressive Disorder Working Group of the Psychiatric Genomic Consortium, 3 Apr 2017, In : Progress in Neuro-Psychopharmacology & Biological Psychiatry. 75, p. 128-134 7 p.

    Research output: Contribution to journalArticle

  45. Genetics of stroke in a UK African ancestry case-control study: South London Ethnicity and Stroke Study

    Traylor, M., Rutten-Jacobs, L., Curtis, C., Patel, H., Breen, G., Newhouse, S., Lewis, C. M. & Markus, H. S., Apr 2017, In : Neurol Genet. 3, 2, p. e142

    Research output: Contribution to journalArticle

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