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Research Outputs

  1. 2017
  2. The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)

    Percie du Sert, N., Alfieri, A., Allan, S. M., Carswell, H. V., Deuchar, G. A., Farr, T. D., Flecknell, P., Gallagher, L., Gibson, C. L., Haley, M. J., Macleod, M. R., McColl, B. W., McCabe, C., Morancho, A., Moon, L. DF., O'Neill, M. J., Pérez de Puig, I., Planas, A., Ragan, C. I., Rosell, A. & 10 others, Roy, L. A., Ryder, K. O., Simats, A., Sena, E. S., Sutherland, B. A., Tricklebank, M. D., Trueman, R. C., Whitfield, L., Wong, R. & Macrae, I. M., 11 Nov 2017, In : Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 37, 11, p. 3488-3517

    Research output: Contribution to journalArticle

  3. The role of intrinsic disorder and dynamics in the assembly and function of the type II secretion system

    Gu, S., Shevchik, V. E., Shaw, R., Pickersgill, R. W. & Garnett, J. A., 1 Oct 2017, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1865, 10, p. 1255-1266 12 p.

    Research output: Contribution to journalReview article

  4. The Experimental Design Assistant

    du Sert, N. P., Bamsey, I., Bate, S. T., Berdoy, M., Clark, R. A., Cuthill, I. C., Fry, D., Karp, N. A., Macleod, M., Moon, L., Stanford, S. C. & Lings, B., 29 Sep 2017, In : NATURE METHODS.

    Research output: Contribution to journalLetter

  5. The Experimental Design Assistant

    Percie du Sert, N., Bamsey, I., Bate, S. T., Berdoy, M., Clark, R. A., Cuthill, I., Fry, D., Karp, N. A., Macleod, M., Moon, L., Stanford, S. C. & Lings, B., 28 Sep 2017, In : PL o S Biology. 15, 9, e2003779.

    Research output: Contribution to journalArticle

  6. Developing a data sharing community for spinal cord injury research

    Moon, L. D., Sep 2017, In : Experimental Neurology. 295, p. 135-143

    Research output: Contribution to journalArticle

  7. The Function of FGFR1 Signalling in the Spinal Cord: Therapeutic Approaches Using FGFR1 Ligands after Spinal Cord Injury

    Haenzi, B. & Moon, L. D. F., 18 Jan 2017, In : Neural Plasticity. 2017, 13 p., 2740768.

    Research output: Contribution to journalArticle

  8. 2016
  9. Crystal structure of the CupB6 adhesive tip from the chaperone-usher family of pili from Pseudomonas aeruginosa

    Rasheed, M., Garnett, J., Pérez-Dorado, I., Muhl, D., Filloux, A. & Matthews, S., 1 Nov 2016, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1864, 11, p. 1500-1505 6 p.

    Research output: Contribution to journalArticle

  10. Crystal structure and analysis of HdaB: The enteroaggregative Escherichia coli AAF/IV pilus tip protein

    Lee, W. C., Matthews, S. & Garnett, J. A., 1 Oct 2016, In : Protein science. p. 1898-1905 8 p.

    Research output: Contribution to journalArticle

  11. Staphylococcal Bap Proteins Build Amyloid Scaffold Biofilm Matrices in Response to Environmental Signals

    Taglialegna, A., Navarro, S., Ventura, S., Garnett, J. A., Matthews, S., Penades, J. R., Lasa, I. & Valle, J., 21 Jun 2016, In : PLoS Pathogens. 12, 6, e1005711.

    Research output: Contribution to journalArticle

  12. Analysis of longitudinal data from animals with missing values using SPSS

    Duricki, D. A., Soleman, S. & Moon, L. D. F., Jun 2016, In : Nature Protocols. 11, 6, p. 1112-1129 18 p.

    Research output: Contribution to journalArticle

  13. The Adaptor Protein CD2AP Is a Coordinator of Neurotrophin Signaling-Mediated Axon Arbor Plasticity

    Harrison, B. J., Venkat, G., Lamb, J. L., Hutson, T. H., Drury, C., Rau, K. K., Bunge, M. B., Mendell, L. M., Gage, F. H., Johnson, R. D., Hill, C. E., Rouchka, E. C., Moon, L. D. F. & Petruska, J. C., 13 Apr 2016, In : Journal of Neuroscience. 36, 15, p. 4259-75 17 p.

    Research output: Contribution to journalArticle

  14. Overexpression of the Fibroblast Growth Factor Receptor 1 (FGFR1) in a Model of Spinal Cord Injury in Rats

    Haenzi, B., Gers-Barlag, K., Akhoundzadeh, H., Hutson, T. H., Menezes, S. C., Bunge, M. B. & Moon, L. D. F., 25 Mar 2016, In : PLoS ONE. 11, 3, p. e0150541

    Research output: Contribution to journalArticle

  15. Delayed intramuscular human neurotrophin-3 improves recovery in adult and elderly rats after stroke

    Duricki, D. A., Hutson, T. H., Kathe, C., Soleman, S., Gonzalez-Carter, D., Petruska, J. C., Shine, H. D., Chen, Q., Wood, T. C., Bernanos, M., Cash, D., Williams, S. C. R., Gage, F. H. & Moon, L. D. F., Jan 2016, In : Brain : a journal of neurology. 139, 1, p. 259-275

    Research output: Contribution to journalArticle

  16. 2015
  17. Transcriptional changes in sensory ganglia associated with primary afferent axon collateral sprouting in spared dermatome model

    Harrison, B. J., Venkat, G., Hutson, T., Rau, K. K., Bunge, M. B., Mendell, L. M., Gage, F. H., Johnson, R. D., Hill, C., Rouchka, E. C., Moon, L. & Petruska, J. C., 1 Dec 2015, In : Genomics Data. 6, p. 249-252 4 p.

    Research output: Contribution to journalArticle

  18. Let's be certain about sartans (and other potential new therapies for CNS injury)

    Moon, L., Nov 2015, In : Brain : a journal of neurology. 138, Pt 11, p. 3136-9 4 p.

    Research output: Contribution to journalArticle

  19. Structural insight into the TRIAP1/PRELI-like domain family of mitochondrial phospholipid transfer complexes

    Miliara, X., Garnett, J. A., Tatsuta, T., Abid Ali, F., Baldie, H., Pérez-Dorado, I., Simpson, P., Yague, E., Langer, T. & Matthews, S., 1 Jul 2015, In : EMBO Reports. 16, 7, p. 824-835 12 p.

    Research output: Contribution to journalArticle

  20. Experimental design and analysis and their reporting: new guidance for publication in BJP

    Curtis, M. J., Bond, R. A., Spina, D., Ahluwalia, A., Alexander, S. P. A., Giembycz, M. A., Gilchrist, A., Hoyer, D., Insel, P. A., Izzo, A. A., Lawrence, A. J., MacEwan, D. J., Moon, L. D. F., Wonnacott, S., Weston, A. H. & McGrath, J. C., Jul 2015, In : British Journal of Pharmacology. 172, 14, p. 3461-3471 11 p.

    Research output: Contribution to journalEditorial

  21. Structure-function analysis reveals that the Pseudomonas aeruginosa Tps4 two-partner secretion system is involved in CupB5 translocation

    Garnett, J. A., Muhl, D., Douse, C. H., Hui, K., Busch, A., Omisore, A., Yang, Y., Simpson, P., Marchant, J., Waksman, G., Matthews, S. & Filloux, A., 1 May 2015, In : Protein science. 24, 5, p. 670-687 18 p.

    Research output: Contribution to journalArticle

  22. Structural Insight into Archaic and Alternative Chaperone-Usher Pathways Reveals a Novel Mechanism of Pilus Biogenesis

    Pakharukova, N., Garnett, J. A., Tuittila, M., Paavilainen, S., Diallo, M., Xu, Y., Matthews, S. J. & Zavialov, A. V., 2015, In : PLoS Pathogens. 11, 11, e1005269.

    Research output: Contribution to journalArticle

  23. Structural analysis of haemoglobin binding by HpuA from the Neisseriaceae family

    Wong, C. T., Xu, Y., Gupta, A., Garnett, J. A., Matthews, S. J. & Hare, S. A., 2015, In : Nature Communications. 6, 10172.

    Research output: Contribution to journalArticle

  24. 2014
  25. The Escherichia coli effector EspJ blocks Src kinase activity via amidation and ADP ribosylation

    Young, J. C., Clements, A., Lang, A. E., Garnett, J. A., Munera, D., Arbeloa, A., Pearson, J., Hartland, E. L., Matthews, S. J., Mousnier, A., Barry, D. J., Way, M., Schlosser, A., Aktories, K. & Frankel, G., 19 Dec 2014, In : Nature Communications. 5, 5887 .

    Research output: Contribution to journalArticle

  26. Crystal structures of stapled and hydrogen bond surrogate peptides targeting a fully buried protein-helix interaction

    Douse, C. H., Maas, S. J., Thomas, J. C., Garnett, J. A., Sun, Y., Cota, E. & Tate, E. W., 17 Oct 2014, In : Acs Chemical Biology. 9, 10, p. 2204-2209 6 p.

    Research output: Contribution to journalArticle

  27. A new method to determine in vivo interactomes reveals binding of the Legionella pneumophila effector PieE to multiple rab GTPases

    Mousnier, A., Schroeder, G. N., Stoneham, C. A., So, E. C., Garnett, J. A., Yu, L., Matthews, S. J., Choudhary, J. S., Hartland, E. L. & Frankel, G., 12 Aug 2014, In : Mbio. 5, 4, e01148-14.

    Research output: Contribution to journalArticle

  28. The peptide-binding cavity is essential for ALS3-mediated adhesion of Candida albicans to human cells

    Lin, J., Oh, S. H., Jones, R., Garnett, J. A., Salgado, P. S., Rusnakova, S., Matthews, S. J., Hoyer, L. L. & Cota, E., 27 Jun 2014, In : Journal of Biological Chemistry. 289, 26, p. 18401-18412 12 p.

    Research output: Contribution to journalArticle

  29. The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors

    Lambert, S. M., Langley, D. R., Garnett, J. A., Angell, R., Richard, K., Meanwell, N. A. & Matthews, S. J., Jun 2014, In : Protein science. 23, 6, p. 723-734 12 p.

    Research output: Contribution to journalArticle

  30. CategoryCompare, an analytical tool based on feature annotations

    Flight, R. M., Harrison, B. J., Mohammad, F., Bunge, M. B., Moon, L. D. F., Petruska, J. C. & Rouchka, E. C., Apr 2014, In : Frontiers in Genetics. 5, N/A, 13 p., 98.

    Research output: Contribution to journalArticle

  31. Structural Insight into Host Recognition by Aggregative Adherence Fimbriae of Enteroaggregative Escherichia coli

    Berry, A. A., Yang, Y., Pakharukova, N., Garnett, J. A., Lee, W. C., Cota, E., Marchant, J., Roy, S., Tuittila, M., Liu, B., Inman, K. G., Ruiz-Perez, F., Mandomando, I., Nataro, J. P., Zavialov, A. V. & Matthews, S., 1 Jan 2014, In : PLoS Pathogens. 10, 9

    Research output: Contribution to journalArticle

  32. Minimum Information About a Spinal Cord Injury Experiment (MIASCI): a proposed reporting standard for spinal cord injury experiments

    Lemmon, V. P., Ferguson, A. R., Popovich, P. G., Xu, X-M., Snow, D. M., Igarashi, M., Beattie, C. E., Bixby, J. L., Consortium, M., Abeyruwan, S. W., Beattie, M. S., Bethea, J., Bradke, F., Bresnahan, J. C., Bunge, M. B., Callahan, A., David, S., Dunlop, S. A., Fawcett, J., Fehlings, M. & 59 others, Fischer, I., Giger, R. J., Goshima, Y., Grimpe, B., Hagg, T., Hall, E. D., Harrison, B. J., Harvey, A. R., He, C., He, Z., Hirata, T., Hoke, A., Hulsebosch, C. E., Hurtado, A., Jain, A., Kadoya, K., Kamiguchi, H., Kengaku, M., Kocsis, J. D., Kwon, B. K., Lee, J. K., Liebl, D. J., Liu, S-J., Lowery, L. A., Mandrekar-Colucci, S., Martin, J. H., Mason, C. A., McTigue, D. M., Mokarram, N., Moon, L. D., Muller, H. W., Nakamura, T., Namba, T., Nishibe, M., Oinuma, I., Oudega, M., Pleasure, D. E., Raisman, G., Rasband, M. N., Reier, P. J., Santiago-Medina, M., Schwab, J. M., Schwab, M. E., Shinmyo, Y., Silver, J., Smith, G. M., So, K-F., Sofroniew, M. V., Strittmatter, S. M., Tuszynski, M. H., Twiss, J. L., Visser, U., Watkins, T. A., Wu, W., Yoon, S. O., Yuzaki, M., Zheng, B., Zhou, F. & Zou, Y., 2014, In : Journal of Neurotrauma.

    Research output: Contribution to journalArticle

  33. The use of an adeno-associated viral vector for efficient bicistronic expression of two genes in the central nervous system

    Hutson, T. H., Kathe, C., Menezes, S. C., Rooney, M-C., Bueler, H. & Moon, L. D. F., 2014, Axon Growth and Regeneration: Methods and Protocols. Murray, A. J. (ed.). N/A ed. N/A: Springer New York, Vol. N/A. p. 189-207 19 p. (Methods in Molecular Biology; vol. 1162).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  34. 2013
  35. Response to the comment published in ATLA, on the declaration on openness on animal research: Concordat on Openness on Animal Research

    Jarrett, W., Watts, G., Allan, C., Brazier, M., Clark, P., Deeny, A., Lee, N., Moon, L., Robinson, V., Taylor, D., Wells, D. & Willis, L. P., May 2013, In : ATLA. 41, 2, p. 195-196 2 p.

    Research output: Contribution to journalArticle

  36. Therapeutics targeting nogo-a hold promise for stroke restoration

    Kumar, P. & Moon, L. D. F., 1 Mar 2013, In : Cns & Neurological Disorders-Drug Targets. 12, 2, p. 200-8 9 p.

    Research output: Contribution to journalArticle

  37. Lentiviral vector-mediated RNA silencing in the CNS

    Hutson, T. H., Foster, E., Moon, L. D. F. & Yáñez-Muñoz, R. J., 2013, In : Human gene therapy methods. 40 p.

    Research output: Contribution to journalArticle

  38. 2012
  39. Interactions in bacterial biofilm development: A structural perspective

    Garnett, J. A. & Matthews, S., 1 Dec 2012, In : Current Protein and Peptide Science. 13, 8, p. 739-755 17 p.

    Research output: Contribution to journalArticle

  40. Efficient gene expression from integration-deficient lentiviral vectors in the spinal cord

    Peluffo, H., Foster, E., Ahmed, S. G., Lago, N., Hutson, T. H., Moon, L., Yip, P., Wanisch, K., Caraballo-Miralles, V., Olmos, G., Lladó, J., McMahon, S. B. & Yáñez-Muñoz, R. J., 18 Oct 2012, In : Gene Therapy,.

    Research output: Contribution to journalArticle

  41. Peripheral Nervous System Genes Expressed in Central Neurons Induce Growth on Inhibitory Substrates

    Buchser, W. J., Smith, R. P., Pardinas, J. R., Haddox, C. L., Hutson, T., Moon, L., Hoffman, S. R., Bixby, J. L. & Lemmon, V. P., 6 Jun 2012, In : PLoS ONE. 7, 6, 17 p., e38101.

    Research output: Contribution to journalArticle

  42. Promoting crystallisation of the Salmonella enteritidis fimbriae 14 pilin SefD using deuterium oxide

    Liu, B., Garnett, J. A., Lee, W. C., Lin, J., Salgado, P., Taylor, J., Xu, Y., Lambert, S., Cota, E. & Matthews, S., 4 May 2012, In : Biochemical and Biophysical Research Communications. 421, 2, p. 208-213 6 p.

    Research output: Contribution to journalArticle

  43. Structural insights into the biogenesis and biofilm formation by the Escherichia coli common pilus

    Garnett, J. A., Martínez-Santos, V. I., Saldaña, Z., Pape, T., Hawthorne, W., Chan, J., Simpson, P. J., Cota, E., Puente, J. L., Girón, J. A. & Matthews, S., 6 Mar 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 10, p. 3950-3955 6 p.

    Research output: Contribution to journalArticle

  44. Structural insight into the role of Streptococcus parasanguinis Fap1 within oral biofilm formation

    Garnett, J. A., Simpson, P. J., Taylor, J., Benjamin, S. V., Tagliaferri, C., Cota, E., Chen, Y. Y. M., Wu, H. & Matthews, S., 6 Jan 2012, In : Biochemical and Biophysical Research Communications. 417, 1, p. 421-426 6 p.

    Research output: Contribution to journalArticle

  45. Corticospinal tract transduction: a comparison of seven adeno-associated viral vector serotypes and a non-integrating lentiviral vector

    Hutson, T. H., Verhaagen, J., Yanez-Munoz, R. J. & Moon, L. D. F., Jan 2012, In : Gene Therapy. 19, 1, p. 49 - 60 12 p.

    Research output: Contribution to journalArticle

  46. 2011
  47. The role of Sialyl glycan recognition in host tissue tropism of the avian parasite Eimeria Tenella

    Lai, L., Bumstead, J., Liu, Y., Garnett, J., Campanero-Rhodes, M. A., Blake, D. P., Palma, A. S., Chai, W., Ferguson, D. J. P., Simpson, P., Feizi, T., Tomley, F. M. & Matthews, S., 1 Oct 2011, In : PLoS Pathogens. 7, 10, e1002296.

    Research output: Contribution to journalArticle

  48. Will stem cell therapies be safe and effective for treating spinal cord injuries?

    Thomas, K. E. & Moon, L. D. F., Jun 2011, In : British Medical Bulletin. 98, 1, p. 127 - 142 16 p.

    Research output: Contribution to journalArticle

  49. Complete 1H, 13C and 15N NMR assignments for donor-strand complemented AafA, the major pilin of aggregative adherence fimbriae (AAF/II) from enteroaggregative E. coli

    Yang, Y., Berry, A. A., Lee, W. C., Garnett, J. A., Marchant, J., Levine, J. A., Simpson, P. J., Fogel, S. A., Varney, K. M., Matthews, S. J., Nataro, J. P. & Inman, K. G., 1 Apr 2011, In : Biomolecular NMR Assignments. 5, 1, p. 1-5 5 p.

    Research output: Contribution to journalArticle

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