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Research Outputs

  1. 2017
  2. The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)

    Percie du Sert, N., Alfieri, A., Allan, S. M., Carswell, H. V., Deuchar, G. A., Farr, T. D., Flecknell, P., Gallagher, L., Gibson, C. L., Haley, M. J., Macleod, M. R., McColl, B. W., McCabe, C., Morancho, A., Moon, L. DF., O'Neill, M. J., Pérez de Puig, I., Planas, A., Ragan, C. I., Rosell, A. & 10 others, Roy, L. A., Ryder, K. O., Simats, A., Sena, E. S., Sutherland, B. A., Tricklebank, M. D., Trueman, R. C., Whitfield, L., Wong, R. & Macrae, I. M., 11 Nov 2017, In : Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 37, 11, p. 3488-3517

    Research output: Contribution to journalArticle

  3. The Experimental Design Assistant

    du Sert, N. P., Bamsey, I., Bate, S. T., Berdoy, M., Clark, R. A., Cuthill, I. C., Fry, D., Karp, N. A., Macleod, M., Moon, L., Stanford, S. C. & Lings, B., 29 Sep 2017, In : NATURE METHODS.

    Research output: Contribution to journalLetter

  4. The Experimental Design Assistant

    Percie du Sert, N., Bamsey, I., Bate, S. T., Berdoy, M., Clark, R. A., Cuthill, I., Fry, D., Karp, N. A., Macleod, M., Moon, L., Stanford, S. C. & Lings, B., 28 Sep 2017, In : PL o S Biology. 15, 9, e2003779.

    Research output: Contribution to journalArticle

  5. Developing a data sharing community for spinal cord injury research

    Moon, L. D., Sep 2017, In : Experimental Neurology. 295, p. 135-143

    Research output: Contribution to journalArticle

  6. The Function of FGFR1 Signalling in the Spinal Cord: Therapeutic Approaches Using FGFR1 Ligands after Spinal Cord Injury

    Haenzi, B. & Moon, L. D. F., 18 Jan 2017, In : Neural Plasticity. 2017, 13 p., 2740768.

    Research output: Contribution to journalArticle

  7. 2016
  8. Crystal structure of the CupB6 adhesive tip from the chaperone-usher family of pili from Pseudomonas aeruginosa

    Rasheed, M., Garnett, J., Pérez-Dorado, I., Muhl, D., Filloux, A. & Matthews, S., 1 Nov 2016, In : Biochimica et Biophysica Acta - Proteins and Proteomics. 1864, 11, p. 1500-1505 6 p.

    Research output: Contribution to journalArticle

  9. Crystal structure and analysis of HdaB: The enteroaggregative Escherichia coli AAF/IV pilus tip protein

    Lee, W. C., Matthews, S. & Garnett, J. A., 1 Oct 2016, In : Protein science. p. 1898-1905 8 p.

    Research output: Contribution to journalArticle

  10. Staphylococcal Bap Proteins Build Amyloid Scaffold Biofilm Matrices in Response to Environmental Signals

    Taglialegna, A., Navarro, S., Ventura, S., Garnett, J. A., Matthews, S., Penades, J. R., Lasa, I. & Valle, J., 21 Jun 2016, In : PLoS Pathogens. 12, 6, e1005711.

    Research output: Contribution to journalArticle

  11. Analysis of longitudinal data from animals with missing values using SPSS

    Duricki, D. A., Soleman, S. & Moon, L. D. F., Jun 2016, In : Nature Protocols. 11, 6, p. 1112-1129 18 p.

    Research output: Contribution to journalArticle

  12. The Adaptor Protein CD2AP Is a Coordinator of Neurotrophin Signaling-Mediated Axon Arbor Plasticity

    Harrison, B. J., Venkat, G., Lamb, J. L., Hutson, T. H., Drury, C., Rau, K. K., Bunge, M. B., Mendell, L. M., Gage, F. H., Johnson, R. D., Hill, C. E., Rouchka, E. C., Moon, L. D. F. & Petruska, J. C., 13 Apr 2016, In : Journal of Neuroscience. 36, 15, p. 4259-75 17 p.

    Research output: Contribution to journalArticle

  13. Overexpression of the Fibroblast Growth Factor Receptor 1 (FGFR1) in a Model of Spinal Cord Injury in Rats

    Haenzi, B., Gers-Barlag, K., Akhoundzadeh, H., Hutson, T. H., Menezes, S. C., Bunge, M. B. & Moon, L. D. F., 25 Mar 2016, In : PLoS ONE. 11, 3, p. e0150541

    Research output: Contribution to journalArticle

  14. Delayed intramuscular human neurotrophin-3 improves recovery in adult and elderly rats after stroke

    Duricki, D. A., Hutson, T. H., Kathe, C., Soleman, S., Gonzalez-Carter, D., Petruska, J. C., Shine, H. D., Chen, Q., Wood, T. C., Bernanos, M., Cash, D., Williams, S. C. R., Gage, F. H. & Moon, L. D. F., Jan 2016, In : Brain : a journal of neurology. 139, 1, p. 259-275

    Research output: Contribution to journalArticle

  15. 2015
  16. Transcriptional changes in sensory ganglia associated with primary afferent axon collateral sprouting in spared dermatome model

    Harrison, B. J., Venkat, G., Hutson, T., Rau, K. K., Bunge, M. B., Mendell, L. M., Gage, F. H., Johnson, R. D., Hill, C., Rouchka, E. C., Moon, L. & Petruska, J. C., 1 Dec 2015, In : Genomics Data. 6, p. 249-252 4 p.

    Research output: Contribution to journalArticle

  17. Let's be certain about sartans (and other potential new therapies for CNS injury)

    Moon, L., Nov 2015, In : Brain : a journal of neurology. 138, Pt 11, p. 3136-9 4 p.

    Research output: Contribution to journalArticle

  18. Structural insight into the TRIAP1/PRELI-like domain family of mitochondrial phospholipid transfer complexes

    Miliara, X., Garnett, J. A., Tatsuta, T., Abid Ali, F., Baldie, H., Pérez-Dorado, I., Simpson, P., Yague, E., Langer, T. & Matthews, S., 1 Jul 2015, In : EMBO Reports. 16, 7, p. 824-835 12 p.

    Research output: Contribution to journalArticle

  19. Structure-function analysis reveals that the Pseudomonas aeruginosa Tps4 two-partner secretion system is involved in CupB5 translocation

    Garnett, J. A., Muhl, D., Douse, C. H., Hui, K., Busch, A., Omisore, A., Yang, Y., Simpson, P., Marchant, J., Waksman, G., Matthews, S. & Filloux, A., 1 May 2015, In : Protein science. 24, 5, p. 670-687 18 p.

    Research output: Contribution to journalArticle

  20. Structural Insight into Archaic and Alternative Chaperone-Usher Pathways Reveals a Novel Mechanism of Pilus Biogenesis

    Pakharukova, N., Garnett, J. A., Tuittila, M., Paavilainen, S., Diallo, M., Xu, Y., Matthews, S. J. & Zavialov, A. V., 2015, In : PLoS Pathogens. 11, 11, e1005269.

    Research output: Contribution to journalArticle

  21. Structural analysis of haemoglobin binding by HpuA from the Neisseriaceae family

    Wong, C. T., Xu, Y., Gupta, A., Garnett, J. A., Matthews, S. J. & Hare, S. A., 2015, In : Nature Communications. 6, 10172.

    Research output: Contribution to journalArticle

  22. 2014
  23. The Escherichia coli effector EspJ blocks Src kinase activity via amidation and ADP ribosylation

    Young, J. C., Clements, A., Lang, A. E., Garnett, J. A., Munera, D., Arbeloa, A., Pearson, J., Hartland, E. L., Matthews, S. J., Mousnier, A., Barry, D. J., Way, M., Schlosser, A., Aktories, K. & Frankel, G., 19 Dec 2014, In : Nature Communications. 5, 5887 .

    Research output: Contribution to journalArticle

  24. Crystal structures of stapled and hydrogen bond surrogate peptides targeting a fully buried protein-helix interaction

    Douse, C. H., Maas, S. J., Thomas, J. C., Garnett, J. A., Sun, Y., Cota, E. & Tate, E. W., 17 Oct 2014, In : Acs Chemical Biology. 9, 10, p. 2204-2209 6 p.

    Research output: Contribution to journalArticle

  25. A new method to determine in vivo interactomes reveals binding of the Legionella pneumophila effector PieE to multiple rab GTPases

    Mousnier, A., Schroeder, G. N., Stoneham, C. A., So, E. C., Garnett, J. A., Yu, L., Matthews, S. J., Choudhary, J. S., Hartland, E. L. & Frankel, G., 12 Aug 2014, In : Mbio. 5, 4, e01148-14.

    Research output: Contribution to journalArticle

  26. The peptide-binding cavity is essential for ALS3-mediated adhesion of Candida albicans to human cells

    Lin, J., Oh, S. H., Jones, R., Garnett, J. A., Salgado, P. S., Rusnakova, S., Matthews, S. J., Hoyer, L. L. & Cota, E., 27 Jun 2014, In : Journal of Biological Chemistry. 289, 26, p. 18401-18412 12 p.

    Research output: Contribution to journalArticle

  27. The crystal structure of NS5A domain 1 from genotype 1a reveals new clues to the mechanism of action for dimeric HCV inhibitors

    Lambert, S. M., Langley, D. R., Garnett, J. A., Angell, R., Richard, K., Meanwell, N. A. & Matthews, S. J., Jun 2014, In : Protein science. 23, 6, p. 723-734 12 p.

    Research output: Contribution to journalArticle

  28. CategoryCompare, an analytical tool based on feature annotations

    Flight, R. M., Harrison, B. J., Mohammad, F., Bunge, M. B., Moon, L. D. F., Petruska, J. C. & Rouchka, E. C., Apr 2014, In : Frontiers in Genetics. 5, N/A, 13 p., 98.

    Research output: Contribution to journalArticle

  29. Structural Insight into Host Recognition by Aggregative Adherence Fimbriae of Enteroaggregative Escherichia coli

    Berry, A. A., Yang, Y., Pakharukova, N., Garnett, J. A., Lee, W. C., Cota, E., Marchant, J., Roy, S., Tuittila, M., Liu, B., Inman, K. G., Ruiz-Perez, F., Mandomando, I., Nataro, J. P., Zavialov, A. V. & Matthews, S., 1 Jan 2014, In : PLoS Pathogens. 10, 9

    Research output: Contribution to journalArticle

  30. Minimum Information About a Spinal Cord Injury Experiment (MIASCI): a proposed reporting standard for spinal cord injury experiments

    Lemmon, V. P., Ferguson, A. R., Popovich, P. G., Xu, X-M., Snow, D. M., Igarashi, M., Beattie, C. E., Bixby, J. L., Consortium, M., Abeyruwan, S. W., Beattie, M. S., Bethea, J., Bradke, F., Bresnahan, J. C., Bunge, M. B., Callahan, A., David, S., Dunlop, S. A., Fawcett, J., Fehlings, M. & 59 others, Fischer, I., Giger, R. J., Goshima, Y., Grimpe, B., Hagg, T., Hall, E. D., Harrison, B. J., Harvey, A. R., He, C., He, Z., Hirata, T., Hoke, A., Hulsebosch, C. E., Hurtado, A., Jain, A., Kadoya, K., Kamiguchi, H., Kengaku, M., Kocsis, J. D., Kwon, B. K., Lee, J. K., Liebl, D. J., Liu, S-J., Lowery, L. A., Mandrekar-Colucci, S., Martin, J. H., Mason, C. A., McTigue, D. M., Mokarram, N., Moon, L. D., Muller, H. W., Nakamura, T., Namba, T., Nishibe, M., Oinuma, I., Oudega, M., Pleasure, D. E., Raisman, G., Rasband, M. N., Reier, P. J., Santiago-Medina, M., Schwab, J. M., Schwab, M. E., Shinmyo, Y., Silver, J., Smith, G. M., So, K-F., Sofroniew, M. V., Strittmatter, S. M., Tuszynski, M. H., Twiss, J. L., Visser, U., Watkins, T. A., Wu, W., Yoon, S. O., Yuzaki, M., Zheng, B., Zhou, F. & Zou, Y., 2014, In : Journal of Neurotrauma.

    Research output: Contribution to journalArticle

  31. 2013
  32. Response to the comment published in ATLA, on the declaration on openness on animal research: Concordat on Openness on Animal Research

    Jarrett, W., Watts, G., Allan, C., Brazier, M., Clark, P., Deeny, A., Lee, N., Moon, L., Robinson, V., Taylor, D., Wells, D. & Willis, L. P., May 2013, In : ATLA. 41, 2, p. 195-196 2 p.

    Research output: Contribution to journalArticle

  33. Therapeutics targeting nogo-a hold promise for stroke restoration

    Kumar, P. & Moon, L. D. F., 1 Mar 2013, In : Cns & Neurological Disorders-Drug Targets. 12, 2, p. 200-8 9 p.

    Research output: Contribution to journalArticle

  34. Lentiviral vector-mediated RNA silencing in the CNS

    Hutson, T. H., Foster, E., Moon, L. D. F. & Yáñez-Muñoz, R. J., 2013, In : Human gene therapy methods. 40 p.

    Research output: Contribution to journalArticle

  35. 2012
  36. Interactions in bacterial biofilm development: A structural perspective

    Garnett, J. A. & Matthews, S., 1 Dec 2012, In : Current Protein and Peptide Science. 13, 8, p. 739-755 17 p.

    Research output: Contribution to journalArticle

  37. Efficient gene expression from integration-deficient lentiviral vectors in the spinal cord

    Peluffo, H., Foster, E., Ahmed, S. G., Lago, N., Hutson, T. H., Moon, L., Yip, P., Wanisch, K., Caraballo-Miralles, V., Olmos, G., Lladó, J., McMahon, S. B. & Yáñez-Muñoz, R. J., 18 Oct 2012, In : Gene Therapy,.

    Research output: Contribution to journalArticle

  38. Peripheral Nervous System Genes Expressed in Central Neurons Induce Growth on Inhibitory Substrates

    Buchser, W. J., Smith, R. P., Pardinas, J. R., Haddox, C. L., Hutson, T., Moon, L., Hoffman, S. R., Bixby, J. L. & Lemmon, V. P., 6 Jun 2012, In : PLoS ONE. 7, 6, 17 p., e38101.

    Research output: Contribution to journalArticle

  39. Promoting crystallisation of the Salmonella enteritidis fimbriae 14 pilin SefD using deuterium oxide

    Liu, B., Garnett, J. A., Lee, W. C., Lin, J., Salgado, P., Taylor, J., Xu, Y., Lambert, S., Cota, E. & Matthews, S., 4 May 2012, In : Biochemical and Biophysical Research Communications. 421, 2, p. 208-213 6 p.

    Research output: Contribution to journalArticle

  40. Structural insights into the biogenesis and biofilm formation by the Escherichia coli common pilus

    Garnett, J. A., Martínez-Santos, V. I., Saldaña, Z., Pape, T., Hawthorne, W., Chan, J., Simpson, P. J., Cota, E., Puente, J. L., Girón, J. A. & Matthews, S., 6 Mar 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 10, p. 3950-3955 6 p.

    Research output: Contribution to journalArticle

  41. Structural insight into the role of Streptococcus parasanguinis Fap1 within oral biofilm formation

    Garnett, J. A., Simpson, P. J., Taylor, J., Benjamin, S. V., Tagliaferri, C., Cota, E., Chen, Y. Y. M., Wu, H. & Matthews, S., 6 Jan 2012, In : Biochemical and Biophysical Research Communications. 417, 1, p. 421-426 6 p.

    Research output: Contribution to journalArticle

  42. Corticospinal tract transduction: a comparison of seven adeno-associated viral vector serotypes and a non-integrating lentiviral vector

    Hutson, T. H., Verhaagen, J., Yanez-Munoz, R. J. & Moon, L. D. F., Jan 2012, In : Gene Therapy. 19, 1, p. 49 - 60 12 p.

    Research output: Contribution to journalArticle

  43. 2011
  44. The role of Sialyl glycan recognition in host tissue tropism of the avian parasite Eimeria Tenella

    Lai, L., Bumstead, J., Liu, Y., Garnett, J., Campanero-Rhodes, M. A., Blake, D. P., Palma, A. S., Chai, W., Ferguson, D. J. P., Simpson, P., Feizi, T., Tomley, F. M. & Matthews, S., 1 Oct 2011, In : PLoS Pathogens. 7, 10, e1002296.

    Research output: Contribution to journalArticle

  45. Will stem cell therapies be safe and effective for treating spinal cord injuries?

    Thomas, K. E. & Moon, L. D. F., Jun 2011, In : British Medical Bulletin. 98, 1, p. 127 - 142 16 p.

    Research output: Contribution to journalArticle

  46. Complete 1H, 13C and 15N NMR assignments for donor-strand complemented AafA, the major pilin of aggregative adherence fimbriae (AAF/II) from enteroaggregative E. coli

    Yang, Y., Berry, A. A., Lee, W. C., Garnett, J. A., Marchant, J., Levine, J. A., Simpson, P. J., Fogel, S. A., Varney, K. M., Matthews, S. J., Nataro, J. P. & Inman, K. G., 1 Apr 2011, In : Biomolecular NMR Assignments. 5, 1, p. 1-5 5 p.

    Research output: Contribution to journalArticle

  47. Crystallization and initial crystallographic analysis of the Streptococcus parasanguinis FW213 Fap1 - NRα adhesive domain at pH 5.0

    Garnett, J. A., Ramboarina, S., Lee, W. C., Tagliaferri, C., Wu, W. & Matthews, S., 1 Feb 2011, In : Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 67, 2, p. 274-276 3 p.

    Research output: Contribution to journalArticle

  48. 2010
  49. EspM2 is a RhoA guanine nucleotide exchange factor

    Arbeloa, A., Garnett, J., Lillington, J., Bulgin, R. R., Berger, C. N., Lea, S. M., Matthews, S. & Frankel, G., 1 May 2010, In : Cellular Microbiology. 12, 5, p. 654-664 11 p.

    Research output: Contribution to journalArticle

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