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  1. 2017

  2. Defining the Locus of Dopaminergic Dysfunction in Schizophrenia: A Meta-analysis and Test of the Mesolimbic Hypothesis

    McCutcheon, R., Beck, K., Jauhar, S. & Howes, O. D., 28 Dec 2017, In : Schizophrenia Bulletin.

    Research output: Contribution to journal › Article

  3. Randomised control trial of the effectiveness of an integrated psychosocial health promotion intervention aimed at improving health and reducing substance use in established psychosis (IMPaCT)

    Gaughran, F., Stahl, D., Ismail, K., Greenwood, K., Atakan, Z., Gardner-Sood, P., Stubbs, B., Hopkins, D., Patel, A., Lally, J., Lowe, P., Arbuthnot, M., Orr, D., Corlett, S., Eberhard, J., David, A. S., Murray, R., Smith, S., on behalf of the IMPaCT Team, Harries, B. & 31 others, Moore, S., Bonaccorso, S., Kolliakou, A., O'Brien, C., Featherman, A., Fung, C., Heslin, M., Dalemo, K., Anakwe-Umeh, S., Todd, G., Mushore, M., Mutsatsa, S., Ohlsen, R., Howes, O., Papanastasiou, E., Firdosi, M., Sallis, H., Sambath, I., Di Clemente, G., Breedvelt, J., Joseph, C., Di Forti, M., Odesanya, A., Onagbesan, D., Case, P., Musa, A., Dalton, C., Rudhra, K., Treasure, J., Murphy, C. & Kelly, J., 28 Dec 2017, In : BMC Psychiatry. 17, 1, 14 p., 413.

    Research output: Contribution to journal › Article

  4. Successful Vaginal Delivery following an Abdominal Cerclage Removal in Pre-Term Labour

    Carlisle, N. H., Ridout, A. E. & Shennan, A. H., 15 Dec 2017, In : International Journal of Obstetrics and Gynaecology Study. 1, 1

    Research output: Contribution to journal › Article

  5. Protection of civilians

    Berdal, M., 1 Dec 2017, In : Cambridge Review of International Affairs. 30, 2-3, p. 283-286 4 p.

    Research output: Contribution to journal › Book/Film/Article review

  6. The effect of perinatal brain injury on dopaminergic function and hippocampal volume in adult life

    Froudist-Walsh, S., Bloomfield, M. A., Veronese, M., Kroll, J., Karolis, V. R., Jauhar, S., Bonoldi, I., McGuire, P. K., Kapur, S., Murray, R. M., Nosarti, C. & Howes, O., 28 Nov 2017, In : eLife. 6

    Research output: Contribution to journal › Article

  7. Acute induction of anxiety in humans by delta-9-tetrahydrocannabinol related to amygdalar cannabinoid-1 (CB1) receptors

    Bhattacharyya, S., Egerton, A., Kim, E., Rosso, L., Riano Barros, D., Hammers, A., Brammer, M., Turkheimer, F. E., Howes, O. D. & McGuire, P., 3 Nov 2017, In : Scientific Reports. 7, 1, p. 15025

    Research output: Contribution to journal › Article

  8. 30 Years on: How the Neurodevelopmental Hypothesis of Schizophrenia Morphed into the Developmental Risk Factor Model of Psychosis

    Murray, R. M., Bhavsar, V., Tripoli, G. & Howes, O., Nov 2017, In : Schizophrenia Bulletin. 43, 6, p. 1190-1196 7 p.

    Research output: Contribution to journal › Article

  9. Brain TSPO imaging and gray matter volume in schizophrenia patients and in people at ultra high risk of psychosis: An [(11)C]PBR28 study

    Selvaraj, S., Bloomfield, P. S., Veronese, M., Turkheimer, F. & Howes, O. D., 12 Oct 2017, In : Schizophrenia Research.

    Research output: Contribution to journal › Article

  10. A Test of the Transdiagnostic Dopamine Hypothesis of Psychosis Using Positron Emission Tomographic Imaging in Bipolar Affective Disorder and Schizophrenia

    Jauhar, S., Nour, M. M., Veronese, M., Rogdaki, M., Bonoldi, I., Azis, M., Turkheimer, F., McGuire, P., Young, A. H. & Howes, O. D., 11 Oct 2017, In : JAMA Psychiatry. 74, 12, p. 1206-1213 8 p.

    Research output: Contribution to journal › Article

  11. Altered activation and connectivity in a hippocampal-basal ganglia-midbrain circuit during salience processing in subjects at ultra high risk for psychosis

    Winton-Brown, T., Schmidt, A., Roiser, J. P., Howes, O. D., Egerton, A., Fusar-Poli, P., Bunzeck, N., Grace, A. A., Duzel, E., Kapur, S. & McGuire, P., 3 Oct 2017, In : Translational psychiatry. 7, 10, e1245.

    Research output: Contribution to journal › Article

  12. Cortical GABA In Subjects At Ultra-High Risk Of Psychosis: Relationship To Negative Prodromal Symptoms

    Modinos, G., Simsek, F., Horder, J., Bossong, M. G., Bonoldi, I., Azis, M., Perez, J., Broome, M., Lythgoe, D. J., Stone, J. M., Howes, O. D., Murphy, D. G., Grace, A. A., Allen, P. & McGuire, P., 19 Aug 2017, In : International Journal of Neuropsychopharmacology .

    Research output: Contribution to journal › Article

  13. Antipsychotic treatment resistance in first-episode psychosis: prevalence, subtypes and predictors

    Demjaha, A., Lappin, J. M., Stahl, D., Patel, M. X., MacCabe, J. H., Howes, O. D., Heslin, M., Reininghaus, U. A., Donoghue, K., Lomas, B., Charalambides, M., Onyejiaka, A., Fearon, P., Jones, P., Doody, G., Morgan, C., Dazzan, P. & Murray, R. M., Aug 2017, In : Psychological Medicine. 47, 11, p. 1981-1989 9 p.

    Research output: Contribution to journal › Article

  14. Placental inflammation and its relationship to cervicovaginal fetal fibronectin in preterm birth

    van der Krogt, L., Ridout, A. E., Seed, P. T. & Shennan, A. H., 1 Jul 2017, In : European Journal of Obstetrics Gynecology and Reproductive Biology. 214, p. 173-177 5 p.

    Research output: Contribution to journal › Article

  15. Association of Stimulants With Dopaminergic Alterations in Users of Cocaine, Amphetamine, and Methamphetamine: A Systematic Review and Meta-analysis

    Ashok, A. H., Mizuno, Y., Volkow, N. & Howes, O. D., May 2017, In : JAMA Psychiatry.

    Research output: Contribution to journal › Review article

  16. The dopamine hypothesis of Bipolar Affective Disorder: the state of the art and implications for treatment

    Ashok, A. H., Reis Marques, T. A., Jauhar, S., Nour, M., Goodwin, G. M., Young, A. & Howes, O. D., May 2017, In : Molecular Psychiatry. 22, 5, p. 666-679 14 p.

    Research output: Contribution to journal › Article

  17. Tradução e adaptação transcultural do questionário de função sexual (SFQ) para o Português do Brasil

    Lapa, C. D. O., Rocha, G. P., Reis Marques, T., Howes, O., Smith, S., Monteiro, R. T., Zorzetti, R. & Spanemberg, L., Apr 2017, In : Trends in Psychiatry and Psychotherapy. 39, 2, p. 110-115 6 p.

    Research output: Contribution to journal › Article

  18. Elevated Striatal Dopamine Function in Immigrants and Their Children: A Risk Mechanism for Psychosis

    Egerton, A., Howes, O. D., Houle, S., McKenzie, K., Valmaggia, L. R., Bagby, M. R., Tseng, H-H., Bloomfield, M. A. P., Kenk, M., Bhattacharyya, S., Suridjan, I., Chaddock, C. A., Winton-Brown, T. T., Allen, P., Rusjan, P., Remington, G., Meyer-Lindenberg, A., McGuire, P. K. & Mizrahi, R., 1 Mar 2017, In : Schizophrenia Bulletin. 43, 2, p. 293–301 9 p.

    Research output: Contribution to journal › Article

  19. Regulation of dopaminergic function: an [(18)F]-DOPA PET apomorphine challenge study in humans

    Jauhar, S., Veronese, M., Rogdaki, M., Bloomfield, M., Natesan, S., Turkheimer, F., Kapur, S. & Howes, O. D., 7 Feb 2017, In : Translational psychiatry. 7, 2, p. e1027

    Research output: Contribution to journal › Article

  20. Longitudinal alterations in motivational salience processing in ultra high-risk subjects for psychosis

    Schmidt, A., Antoniades, M., Allen, P., Egerton, A., Chaddock, C., Borgwardt, S. J., Fusar-Poli, P., Roiser, J. P., Howes, O. D. & McGuire, P., Jan 2017, In : Psychological Medicine. p. 243-254 PSM-D-16-00500R2.

    Research output: Contribution to journal › Article

  21. 2016

  22. Treatment-Resistant Schizophrenia: Treatment Response and Resistance in Psychosis (TRRIP) Working Group Consensus Guidelines on Diagnosis and Terminology

    Howes, O. D., McCutcheon, R., Agid, O., de Bartolomeis, A., van Beveren, N. J. M., Birnbaum, M. L., Bloomfield, M. A. P., Bressan, R. A., Buchanan, R. W., Carpenter, W. T., Castle, D. J., Citrome, L., Daskalakis, Z. J., Davidson, M., Drake, R. J., Dursun, S., Ebdrup, B. H., Elkis, H., Falkai, P., Fleischacker, W. W. & 31 others, Gadelha, A., Gaughran, F., Glenthøj, B. Y., Graff-Guerrero, A., Hallak, J. E. C., Honer, W. G., Kennedy, J., Kinon, B. J., Lawrie, S. M., Lee, J., Leweke, F. M., MacCabe, J. H., McNabb, C. B., Meltzer, H., Möller, H-J., Nakajima, S., Pantelis, C., Reis Marques, T., Remington, G., Rossell, S. L., Russell, B. R., Siu, C. O., Suzuki, T., Sommer, I. E., Taylor, D., Thomas, N., Üçok, A., Umbricht, D., Walters, J. T. R., Kane, J. & Correll, C. U., 6 Dec 2016, In : The American Journal of Psychiatry. appiajp201616050503.

    Research output: Contribution to journal › Article

  23. Presynaptic Dopamine Capacity in Patients with Treatment Resistant Schizophrenia Taking Clozapine: An [(18)F]DOPA PET Study

    Kim, E., Howes, O. D., Veronese, M., Beck, K., Seo, S., Park, J. W., Lee, J. S., Lee, Y-S. & Kwon, J. S., 18 Nov 2016, In : Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.

    Research output: Contribution to journal › Article

  24. The effects of Δ9-tetrahydrocannabinol on the dopamine system

    Bloomfield, M. A. P., Ashok, A. H., Volkow, N. D. & Howes, O. D., 16 Nov 2016, In : NATURE. 539, 7629, p. 369-377 9 p.

    Research output: Contribution to journal › Literature review

  25. Should psychiatrists be more cautious about the long-term prophylactic use of antipsychotics?

    Murray, R. M., Quattrone, D., Natesan, S., Van Os, J., Nordentoft, M., Howes, O. D., Di Forti, M. & Taylor, D. M., 1 Nov 2016, In : British Journal of Psychiatry. 209, 5, p. 361 365 p.

    Research output: Contribution to journal › Article

  26. Two distinct patterns of treatment resistance: clinical predictors of treatment resistance in first-episode schizophrenia spectrum psychoses

    Lally, J., Ajnakina, O., Di Forti, M., Trotta, A., Demjaha, A., Kolliakou, A., Mondelli, V., Reis Marques, T., Pariante, C., Dazzan, P., Shergill, S. S., Howes, O. D., David, A. S., MacCabe, J. H., Gaughran, F. & Murray, R. M., Nov 2016, In : Psychological Medicine. 46, 15, p. 3231-3240 10 p.

    Research output: Contribution to journal › Article

  27. Adversity in childhood linked to elevated striatal dopamine function in adulthood

    Egerton, A., Valmaggia, L. R., Howes, O. D., Day, F., Chaddock, C. A., Allen, P., Winton-Brown, T. T., Bloomfield, M. A. P., Bhattacharyya, S., Chilcott, J., Lappin, J. M., Murray, R. M. & McGuire, P., 1 Oct 2016, In : Schizophrenia Research. 176, 2-3, p. 171-176

    Research output: Contribution to journal › Article

  28. The role of genes, stress and dopamine in the development of schizophrenia

    Howes, O. D., Mccutcheon, R., Owen, M. J. & Murray, R., 6 Aug 2016, In : Biological psychiatry.

    Research output: Contribution to journal › Article

  29. Stress and neuroinflammation: A systematic review of the effects of stress on microglia and the implications for mental illness

    Calcia, M. A., Bonsall, D. R., Bloomfield, P. S., Selvaraj, S., Barichello, T. & Howes, O. D., 1 May 2016, In : Psychopharmacology. 233, 9, p. 1637-1650 14 p.

    Research output: Contribution to journal › Review article

  30. Brain-imaging studies of treatment-resistant schizophrenia: a systematic review

    Mouchlianitis, E., McCutcheon, R. & Howes, O. D., May 2016, In : The Lancet Psychiatry. 3, 5, p. 451–463

    Research output: Contribution to journal › Article

  31. Treatment-Resistant Schizophrenia Patients Show Elevated Anterior Cingulate Cortex Glutamate Compared to Treatment-Responsive

    Mouchlianitis, E., Bloomfield, M. A. P., Law, V., Beck, K., Selvaraj, S., Rasquinha, N., Waldman, A., Turkheimer, F. E., Egerton, A., Stone, J. & Howes, O. D., May 2016, In : Schizophrenia Bulletin. 42, 3, p. 744-752

    Research output: Contribution to journal › Article

  32. Prevalence and implications of Truman symptoms in subjects at ultra high risk for psychosis

    Madeira, L., Bonoldi, I., Rocchetti, M., Brandizzi, M., Samson, C., Azis, M., Queen, B., Bossong, M., Allen, P., Perez, J., Howes, O. D., McGuire, P. & Fusar-Poli, P., 30 Apr 2016, In : Psychiatry Research. 238, p. 270-276 7 p.

    Research output: Contribution to journal › Article

  33. An initial investigation of abnormal bodily phenomena in subjects at ultra high risk for psychosis: Their prevalence and clinical implications

    Madeira, L., Bonoldi, I., Rocchetti, M., Samson, C., Azis, M., Queen, B., Bossong, M., Perez, J., Stone, J., Allen, P., Howes, O. D., McGuire, P., Raballo, A., Fusar-Poli, P., Ballerini, M. & Stanghellini, G., 1 Apr 2016, In : Comprehensive Psychiatry. 66, p. 39-45 7 p.

    Research output: Contribution to journal › Article

  34. Clinical correlates of vitamin D deficiency in established psychosis

    Lally, J., Gardner-Sood, P., Firdosi, M., Iyegbe, C., Stubbs, B., Greenwood, K., Murray, R., Smith, S., Howes, O. & Gaughran, F., 2016, In : BMC Psychiatry. 16, p. 1-9 76.

    Research output: Contribution to journal › Article

  35. 2015

  36. Autoantibodies to central nervous system neuronal surface antigens: Psychiatric symptoms and psychopharmacological implications

    Pollak, T., Beck, K., Irani, S. R., Howes, O. D., David, A. S. & McGuire, P. K., 14 Dec 2015, In : Psychopharmacology. 233, 9, p. 1605-1621 17 p.

    Research output: Contribution to journal › Literature review

  37. Very Early Brain Damage Leads to Remodeling of the Working Memory System in Adulthood: A Combined fMRI/Tractography Study

    Froudist-Walsh, S., Karolis, V., Caldinelli, C., Brittain, P. J., Kroll, J., Rodríguez-Toscano, E., Tesse, M., Colquhoun, M., Howes, O., Dell'Acqua, F., Thiebaut de Schotten, M., Murray, R. M., Williams, S. C. R. & Nosarti, C., 2 Dec 2015, In : Journal of Neuroscience. 35, 48, p. 15787-99 13 p.

    Research output: Contribution to journal › Article

  38. Does environmental confounding mask pleiotropic effects of a multiple sclerosis susceptibility variant on vitamin D in psychosis?

    Iyegbe, C., Acharya, A., Lally, J., Gardner-Sood, P., Smith, L., Smith, S., Murray, R. M., Howes, O. D. & Gaughran, F. P., 28 Oct 2015, In : NPJ SCHIZOPHRENIA. 1, 10/28/online, 15036.

    Research output: Contribution to journal › Article

  39. Functional Outcome in People at High Risk for Psychosis Predicted by Thalamic Glutamate Levels and Prefronto-Striatal Activation

    Allen, P., Chaddock, C. A., Egerton, A., Howes, O., Barker, G., Bonoldi, I., Fusar-Poli, P., Murray, R. & McGuire, P., Mar 2015, In : Schizophrenia Bulletin. 41, 2, p. 429-439

    Research output: Contribution to journal › Article

  40. Prevalence of serum N-methyl-D-aspartate receptor autoantibodies in refractory psychosis

    Beck*, K. E., Lally*, J. A., Shergill, S. S., Bloomfield, M. A. P., MacCabe, J. H., Gaughran, F. P. & Howes, O., 1 Feb 2015, In : British Journal of Psychiatry. 206, 2, p. 164-165 2 p.

    Research output: Contribution to journal › Article

  41. 2014

  42. Long-Term Heavy Ketamine Use is Associated with Spatial Memory Impairment and Altered Hippocampal Activation

    Morgan, C. J. A., Dodds, C. M., Furby, H., Pepper, F., Fam, J., Freeman, T. P., Hughes, E., Doeller, C., King, J., Howes, O. & Stone, J. M., 4 Dec 2014, In : Frontiers in psychiatry / Frontiers Research Foundation. 5, 11 p., 149.

    Research output: Contribution to journal › Article

  43. Glutamate, N-acetyl aspartate and psychotic symptoms in chronic ketamine users

    Stone, J. M., Pepper, F., Fam, J., Furby, H., Hughes, E., Morgan, C. & Howes, O. D., May 2014, In : Psychopharmacology. 231, 10, p. 2107-2116 10 p.

    Research output: Contribution to journal › Article

  44. Does human presynaptic striatal dopamine function predict social conformity?

    Stokes, P., Benecke, A., Puraite, J., Bloomfield, M. A., Shotbolt, P., Reeves, S., Lingford-Hughes, A. R., Howes, O. & Egerton, A., Mar 2014, In : Journal of Psychopharmacology. 28, 3, p. 237-243 7 p.

    Research output: Contribution to journal › Article

  45. 2013

  46. Neural and Behavioral Correlates of Aberrant Salience in Individuals at Risk for Psychosis

    Roiser, J. P., Howes, O. D., Chaddock, C. A., Joyce, E. M. & McGuire, P., Nov 2013, In : Schizophrenia Bulletin. 39, 6, p. 1328-1336 9 p., N/A.

    Research output: Contribution to journal › Article

  47. Nature or nurture? Determining the heritability of human striatal dopamine function: an [18F]-DOPA PET study

    Stokes, P., Shotbolt, P., Mehta, M. A., Turkheimer, E., Benecke, A., Copeland, C., Turkheimer, F. E., Lingford-Hughes, A. R. & Howes, O., Feb 2013, In : Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 38, 3, p. 485-491 7 p.

    Research output: Contribution to journal › Article

  48. Mind the mortality gap: The importance of metabolic function in mental illnesses

    Howes, O. D. & Beck, K., 2013, In : Psychopharmacology. 230, 1, p. 1-2 2 p.

    Research output: Contribution to journal › Comment/debate

  49. 2012

  50. Transition to Psychosis Associated With Prefrontal and Subcortical Dysfunction in Ultra High-Risk Individuals

    Allen, P., Luigjes, J., Howes, O., Egerton, A., Hirao, K., Valli, I., Kambeitz, J., Fusar-Poli, P., Broome, M. & McGuire, P., Nov 2012, In : Schizophrenia Bulletin. 38, 6, p. 1268-1276 9 p., N/A.

    Research output: Contribution to journal › Article

  51. Abnormal Relationship Between Medial Temporal Lobe and Subcortical Dopamine Function in People With an Ultra High Risk for Psychosis

    Allen, P., Chaddock, C. A., Howes, O., Egerton, A., Seal, M. L., Fusar-Poli, P., Valli, I., Day, F. & McGuire, P. K., Sep 2012, In : Schizophrenia Bulletin. 38, 5, p. 1040-1049 10 p.

    Research output: Contribution to journal › Article

  52. Interpersonal sensitivity in the at-risk mental state for psychosis

    Masillo, A., Day, F., Laing, J., Howes, O., Fusar-Poli, P., Byrne, M., Bhattacharyya, S., Fiori Nastro, P., Girardi, P., McGuire, P. K. & Valmaggia, L. R., Sep 2012, In : Psychological Medicine. 42, 9, p. 1835-1845 11 p.

    Research output: Contribution to journal › Article

  53. The nature of dopamine dysfunction in schizophrenia and what this means for treatment: Meta-analysis of Imaging Studies

    Howes, O., Kambeitz, J., Kim, E., Stahl, D., Slifstein, M., Abi-Dargham, A. & Kapur, S., 2 Apr 2012, In : Archives of General Psychiatry. 69, 8, p. 776-786 11 p.

    Research output: Contribution to journal › Literature review

  54. Functional brain networks before the onset of psychosis: A prospective fMRI study with graph theoretical analysis

    Lord, L-D., Allen, P., Expert, P., Howes, O., Broome, M., Lambiotte, R., Fusar-Poli, P., Valli, I., McGuire, P. & Turkheimer, F., 2012, In : NeuroImage: Clinical. 1, 1, p. 91-98 8 p., N/A.

    Research output: Contribution to journal › Article

  55. 2007

  56. Las Naciones Unidas a sus sesenta años: ¿un nuevo momento San Francisco?

    Berdal, M., 2007, In : Foro Internacional: Revista Trimestral Publicada por el Colegio de Mexico . XLVII, 1, p. 5 - 35 31 p.

    Research output: Contribution to journal › Article

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