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Research Outputs

  1. 2017
  2. Outcomes of specialist discharge coordination and intermediate care schemes for patients who are homeless: analysis protocol for a population-based historical cohort

    Blackburn, R. M., Hayward, A., Cornes, M., McKee, M., Lewer, D., Whiteford, M., Menezes, D., Luchenski, S., Story, A., Denaxas, S., Tinelli, M., Wurie, F. B., Byng, R., Clark, M. C., Fuller, J., Gabbay, M., Hewett, N., Kilmister, A., Manthorpe, J., Neale, J. & 1 others, Aldridge, R. W., 14 Dec 2017, In : BMJ open. 7, 12, e019282.

    Research output: Contribution to journalArticle

  3. Identifying acceptable components for home-based health promotion services for older people with mild frailty: A qualitative study

    Frost, R., Kharicha, K., Jovicic, A., Liljas, A. E. M., Iliffe, S., Manthorpe, J., Gardner, B., Avgerinou, C., Goodman, C., Drennan, V. M. & Walters, K., 5 Dec 2017, In : Health and Social Care in the Community.

    Research output: Contribution to journalArticle

  4. Identifying acceptable components for home-based health promotion services for older people with mild frailty: A qualitative study

    Frost, R., Kharicha, K., Jovicic, A., Liljas, A. E. M., Iliffe, S., Manthorpe, J., Gardner, B., Avgerinou, C., Goodman, C., Drennan, V. M. & Walters, K., 5 Dec 2017, In : Health and Social Care in the Community.

    Research output: Contribution to journalArticle

  5. Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infants

    Krishnan, M. L., Van Steenwinckel, J., Schang, A., Yan, J., Arnadottir, J., Le Charpentier, T., Csaba, Z., Dournaud, P., Cipriani, S., Auvynet, C., Titomanlio, L., Pansiot, J., Ball, G., Boardman, J. P., Walley, A. J., Saxena, A., Mirza, G., Fleiss, B., Edwards, A. D., Petretto, E. & 1 others, Gressens, P., 1 Dec 2017, In : Nature Communications. 8, 1

    Research output: Contribution to journalArticle

  6. Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease

    Horgusluoglu-Moloch, E., Nho, K., Risacher, S. L., Kim, S., Foroud, T., Shaw, L. M., Trojanowski, J. Q., Aisen, P. S., Petersen, R. C., Jack, C. R., Lovestone, S., Simmons, A., Weiner, M. W. & Saykin, A. J., 1 Dec 2017, In : Neurobiology of Aging. 60, p. 92-103 12 p.

    Research output: Contribution to journalArticle

  7. Home-based health promotion for older people with mild frailty: the HomeHealth intervention development and feasibility RCT

    Walters, K., Frost, R., Kharicha, K., Avgerinou, C., Gardner, B., Ricciardi, F., Hunter, R., Liljas, A., Manthorpe, J., Drennan, V., Wood, J., Goodman, C., Jovicic, A. & Iliffe, S., Dec 2017, In : Health technology assessment (Winchester, England). 21, 73, p. 1-128 128 p.

    Research output: Contribution to journalArticle

  8. Handovers in care homes for older people - their type, timing, and usefulness. Findings from a scoping review

    Moriarty, J., Lipman, V., Norrie, C. M., Elaswarapu, R. & Manthorpe, J., 27 Nov 2017, In : Ageing and Society. p. 1-21 21 p.

    Research output: Contribution to journalArticle

  9. Gambling-Related Harms and Social Work Practice: Findings from a Scoping Review

    Manthorpe, J., Norrie, C. & Bramley, S., 24 Nov 2017, In : Practice. Social Work in Action. 30, 3, p. 187-202 16 p.

    Research output: Contribution to journalArticle

  10. How are compassion fatigue, burnout, and compassion satisfaction affected by quality of working life? Findings from a survey of mental health staff in Italy

    Cetrano, G., Tedeschi, F., Rabbi, L., Gosetti, G., Lora, A., Lamonaca, D., Manthorpe, J. & Amaddeo, F., 21 Nov 2017, In : BMC Health Services Research. 17, 1, 11 p., 755.

    Research output: Contribution to journalArticle

  11. Engaging hard-to-reach groups in health promotion: the views of older people and professionals from a qualitative study in England

    Liljas, A. E. M., Walters, K., Jovicic, A., Manthorpe, J., Iliffe, S., Goodman, C. & Kharicha, K., Nov 2017, In : Lancet. 390, Supplement 3, p. S58

    Research output: Contribution to journalMeeting abstract

  12. DISCOVERY, REPLICATION AND EXTENSION STUDY OF PLASMA PROTEOMIC BIOMARKERS RELATING TO BRAIN AMYLOID BURDEN (CSF Aβ OR AMYLOID-PET) IN THE EMIF-AD BIOMARKER DISCOVERY COHORT: 2017 Abstract Supplement

    Westwood, S., Baird, A. L., Hye, A., Bos, I., Vos, S. J. B., Vandenberghe, R., Scheltens, P., Engelborghs, S., Frisoni, G. B., Molinuevo, J. L., Wallin, A., Lleó, A., Popp, J., Martinez-Lage, P., Snowden, S. G., Legido-Quigley, C., Bertram, L., Barkhof, F., Zetterberg, H., Streffer, J. & 2 others, Visser, P. J. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P361-P362

    Research output: Contribution to journalArticle

  13. PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY: 2017 Abstract Supplement

    Koychev, I. G., Gunn, R. N., Firouzian, A., Lawson, J., Zamboni, G., Ridha, B. H., Sahakian, B., Rowe, J. B., Thomas, A., Rochester, L., Ffytche, D., Howard, R. J., Zetterberg, H., MacKay, C. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P243

    Research output: Contribution to journalPoster abstract

  14. PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY: 2017 Abstract Supplement

    Koychev, I. G., Gunn, R. N., Firouzian, A., Lawson, J., Zamboni, G., Ridha, B. H., Sahakian, B., Rowe, J. B., Thomas, A., Rochester, L., Ffytche, D., Howard, R. J., Zetterberg, H., MacKay, C. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P456-P457

    Research output: Contribution to journalPoster abstract

  15. ‘WORKING TO THE END’: EXPERIENCES OF THE HOME CARE WORKFORCE PROVIDING END-OF-LIFE CARE: 2017 Abstract Supplement

    Samsi, K., Manthorpe, J., Vandrevala, T., Abrams, R., Yeh, I. & D'Astous, V., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P1456-P1457

    Research output: Contribution to journalMeeting abstract

  16. Amyloid beta synaptotoxicity is Wnt–planar cell polarity dependent and blocked by fasudil

    Sellers, K. J., Elliott, C., Jackson, J., Ghosh, A., Ribe, E., Rojo-Sanchís, A., Jarosz-Griffiths, H. H., Watson, I. A., Xia, W., Semenov, M., Morin, P., Hooper, N. M., Porter, R., Preston, J., Al-Shawi, R., Baillie, G., Lovestone, S., Cuadrado, A., Harte, M., Simons, P. & 2 others, Srivastava, D. P. & Killick, R., 19 Oct 2017, In : Alzheimer's & Dementia.

    Research output: Contribution to journalArticle

  17. Reactive astrocyte COX2-PGE2 production inhibits oligodendrocyte maturation in neonatal white matter injury

    Shiow, L. R., Favrais, G., Schirmer, L., Schang, A-L., Cipriani, S., Andres, C., Wright, J. N., Nobuta, H., Fleiss, B., Gressens, P. & Rowitch, D. H., 30 Aug 2017, In : Glia.

    Research output: Contribution to journalArticle

  18. Dementia: Is the biopsychosocial model vindicated? Editorials

    Iliffe, S. & Manthorpe, J., 1 Aug 2017, In : British Journal of General Practice. 67, 661, p. 344-345 2 p.

    Research output: Contribution to journalEditorial

  19. EXPLORING THE RELATIONSHIP BETWEEN ANAEMIA AND ALZHEIMER’S DISEASE: 2017 Abstract Supplement

    Winchester, L., Nevado-Holgado, A. J. & Lovestone, S., 20 Jul 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P221

    Research output: Contribution to journalMeeting abstract

  20. Health and well-being promotion strategies for ‘hard to reach’ older people in England: a mapping exercise

    Iliffe, S., Walters, K., Manthorpe, J., Goodman, C. & Kharicha, K., 20 Jul 2017, In : Primary health care research & development. p. 1-11 11 p.

    Research output: Contribution to journalArticle

  21. Health promotion interventions for community-dwelling older people with mild or pre-frailty: a systematic review and meta-analysis

    Frost, R., Belk, C., Jovicic, A., Ricciardi, F., Kharicha, K., Gardner, B., Iliffe, S., Goodman, C., Manthorpe, J., Drennan, V. M. & Walters, K., 20 Jul 2017, In : BMC Geriatrics . 17, 1, p. 157 157.

    Research output: Contribution to journalArticle

  22. Improving Hospital Discharge Arrangements for People who are Homeless: A Realist Synthesis of the Intermediate Care Literature

    Cornes, M., Whiteford, M., Manthorpe, J., Neale, J., Byng, R., Hewett, N., Clark, M., Alan, K., J, F., Robert, A. & Michela, T., 20 Jul 2017, In : Health and Social Care in the Community.

    Research output: Contribution to journalArticle

  23. NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology

    Rojo, A. I., Pajares, M., Rada, P., Nuñez, A., Nevado-Holgado, A. J., Killik, R., Van Leuven, F., Ribe, E., Lovestone, S., Yamamoto, M. & Cuadrado, A., 5 Jul 2017, In : Redox Biology.

    Research output: Contribution to journalArticle

  24. Exploring the relationship between frequent internet use and health and social care resource use in a community-based cohort of older adults: An observational study in primary care

    Clarke, C. S., Round, J., Morris, S., Kharicha, K., Ford, J., Manthorpe, J., Iliffe, S., Goodman, C. & Walters, K., 1 Jul 2017, In : BMJ Open. 7, 7, e015839.

    Research output: Contribution to journalArticle

  25. DISCOVERY AND VALIDATION OF MULTIMODAL BIOMARKER SIGNATURES RELATING TO ALZHEIMER'S DISEASE PATHOLOGY AND PROGRESSION: 2017 Abstract Supplement

    Westwood, S., Hye, A., Lleó, A., Nevado-Holgado, A. J., Baird, A. L., Wallin, A., Leslie, A., Jimenez, B., Liu, B. Y., Legido-Quigley, C., Dima, D., Ruvolo, D., Holmes, E., D'Hondt, E., Westman, E., Barkhof, F., Frisoni, G. B., Zetterberg, H., Bos, I., Pearce, J. & 27 others, Streffer, J., Molinuevo, J. L., Popp, J., Bertram, L., Whiley, L., Maslen, L., Gomez-Romero, M., David, M., Lewis, M., Kurbatova, N., Ashton, N. J., Voyle, N., Kowalczyk, O., Martinez-Lage, P., Proitsi, P., Scheltens, P., Visser, P. J., Dobson, R. JB., Vandenberghe, R., Engelborghs, S., Vos, S. J. B., Snowden, S. G., Athersuch, T., Ashby, T., Kimhofer, T., Verachtert, W. & Lovestone, S., Jul 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P174-P175

    Research output: Contribution to journalMeeting abstract

  26. Persistently Altered Metabolic Phenotype following Perinatal Excitotoxic Brain Injury

    Blaise, B. J., Schwendimann, L., Chhor, V., Degos, V., Hodson, M. P., Dallmann, G., Keller, M., Gressens, P. & Fleiss, B., Jul 2017, In : Developmental Neuroscience. 39, p. 182-191 10 p.

    Research output: Contribution to journalArticle

  27. Golgi trafficking defects in postnatal microcephaly: The evidence for "Golgipathies"

    Passemard, S., Perez, F., Colin-Lemesre, E., Rasika, S., Gressens, P. & El Ghouzzi, V., Jun 2017, In : Progress in Neurobiology. 153, p. 46-63 18 p.

    Research output: Contribution to journalArticle

  28. Long-Term Neuropathological Changes Associated with Cerebral Palsy in a Nonhuman Primate Model of Hypoxic-Ischemic Encephalopathy

    McAdams, R. M., Fleiss, B., Traudt, C., Schwendimann, L., Snyder, J. M., Haynes, R. L., Natarajan, N., Gressens, P. & Juul, S. E., 10 May 2017, In : Developmental Neuroscience. 39, 1-4, p. 124-140

    Research output: Contribution to journalArticle

  29. Inequalities in receipt of mental and physical healthcare in people with dementia in the UK

    Cooper, C., Lodwick, R., Walters, K., Raine, R., Manthorpe, J., Iliffe, S. & Petersen, I., 1 May 2017, In : Age and Ageing. 46, 3, p. 393-400 8 p., afw208.

    Research output: Contribution to journalArticle

  30. Mitochondrial genes are altered in blood early in Alzheimer's disease

    Lunnon, K., Keohane, A., Pidsley, R., Newhouse, S., Riddoch-Contreras, J., Thubron, E. B., Devall, M., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Schalkwyk, L., Dobson, R., Malik, A. N., Powell, J., Lovestone, S. & Hodges, A., 1 May 2017, In : Neurobiology of Aging. 53, p. 36-47 12 p.

    Research output: Contribution to journalArticle

  31. Our priorities are upside down

    Manthorpe, J. & Lliffe, S., 1 May 2017, In : Journal of Dementia Care. 25, 3, p. 18-20 3 p.

    Research output: Contribution to journalShort survey

  32. Strategies to improve engagement of ‘hard to reach’ older people in research on health promotion: a systematic review

    Liljas, A. E. M., Walters, K., Jovicic, A., Iliffe, S., Manthorpe, J., Goodman, C. & Kharicha, K., 21 Apr 2017, In : BMC Public Health. 17, 1, 349.

    Research output: Contribution to journalArticle

  33. Dexmedetomidine Combined with Therapeutic Hypothermia Is Associated with Cardiovascular Instability and Neurotoxicity in a Piglet Model of Perinatal Asphyxia

    Ezzati, M., Kawano, G., Rocha-Ferreira, E., Alonso-Alconada, D., Hassell, J. K., Broad, K. D., Fierens, I., Fleiss, B., Bainbridge, A., Price, D. L., Kaynezhad, P., Anderson, B., Hristova, M., Tachtsidis, I., Golay, X., Gressens, P., Sanders, R. D. & Robertson, N. J., 8 Apr 2017, In : Developmental Neuroscience.

    Research output: Contribution to journalArticle

  34. Surgery increases cell death and induces changes in gene expression compared with anesthesia alone in the developing piglet brain

    Broad, K. D., Kawano, G., Fierens, I., Rocha-Ferreira, E., Hristova, M., Ezzati, M., Rostami, J., Alonso-Alconada, D., Chaban, B., Hassell, J., Fleiss, B., Gressens, P., Sanders, R. D. & Robertson, N. J., 29 Mar 2017, In : PLoS ONE. 12, 3, 15 p., e0173413.

    Research output: Contribution to journalArticle

  35. The nature of gambling-related harms for adults at risk: a review

    Bramley, S., Norrie, C. M. & Manthorpe, J., 29 Mar 2017, London: King's College, London. 64 p.

    Research output: Book/ReportCommissioned report

  36. Promoting independence, health and well-being for older people: a feasibility study of computer-aided health and social risk appraisal system in primary care

    walters, K., kharicha, K., goodman, C., handley, M., Manthorpe, J., cattan, M., morris, S., clarke, C., Round, J. & Iliffe, S., 24 Mar 2017, In : BMC FAMILY PRACTICE.

    Research output: Contribution to journalArticle

  37. Service use of older people who participate in primary care health promotion: a latent class analysis

    Ford, J. A., Kharicha, K., Clarke, C. S., Clark, A., Iliffe, S., Goodman, C., Manthorpe, J., Steel, N. & Walters, K., 6 Mar 2017, In : BMC Health Services Research. 176

    Research output: Contribution to journalArticle

  38. What do we know about care home managers? Findings of a scoping review

    Orellana, K., Manthorpe, J. & Moriarty, J., 1 Mar 2017, In : Health and Social Care in the Community. 23, 1, p. 366–377. 9 p.

    Research output: Contribution to journalArticle

  39. Do personal budgets increase the risk of abuse? Evidence from English national data

    Ismail, M., Hussein, S. A., Stevens, M. J., Manthorpe, J., Woolham, J. G., Baxter, K., Samsi, K. & Aspinal, F., 27 Feb 2017, In : Journal of Social Policy. 46, 2, p. 291-311

    Research output: Contribution to journalArticle

  40. What do older people experiencing loneliness think about primary care or community based interventions to reduce loneliness?

    Kharicha, K., iliffe, S., Manthorpe, J., chew-graham, C., cattan, M., goodman, C., kirby-barr, M., whitehouse, J. & Walters, K., 23 Feb 2017, In : Health and Social Care in the Community.

    Research output: Contribution to journalArticle

  41. Supporting shared decision-making for older people with multiple health and social care needs: a protocol for a realist synthesis to inform integrated care models.

    Bunn, F., Goodman, C., Manthorpe, J., Durand, M-A., Hodgekinson, I., Rait, G., Millac, P., Davies, S. L., Russell, B. & Wilson, P., 7 Feb 2017, In : BMJ Open. 7

    Research output: Contribution to journalArticle

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