King's College London

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Research Outputs

  1. 2017
  2. Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

    Jason, F., Fuchsberger, C., Mahajan, A., Teslovich, T. M., Agarwala, V., Gaulton, K. J., Caulkins, L., Koesterer, R., Ma, C., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F. & 281 others, Highland, H. M., Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., van de Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B-J., Kim, Y., Kim, Y. J., Kwon, M-S., Lee, J., Lee, S., Lin, K-H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B-G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S-H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C-Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C-C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S-T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., de Angelis, M. H., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A-C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J-Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Scott, L. J., Morris, A. P., Kang, H. M., Altshuler, D., Burtt, N. P., Florez, J. C., Boehnke, M. & McCarthy, M. I., 19 Dec 2017, In : Scientific Data. 4, p. 170179

    Research output: Contribution to journalArticle

  3. Meta-analysis of genome-wide association studies identifies 8 novel loci involved in shape variation of human head hair

    Liu, F., Chen, Y., Zhu, G., Hysi, P. G., Wu, S., Adhikari, K., Breslin, K., Pospiech, E., Hamer, M. A., Peng, F., Muralidharan, C., Acuna-Alonzo, V., Canizales-Quinteros, S., Bedoya, G., Gallo, C., Poletti, G., Rothhammer, F., Bortolini, M. C., Gonzalez-Jose, R., Zeng, C. & 14 others, Xu, S., Jin, L., Uitterlinden, A. G., Ikram, M. A., van Duijn, C. M., Nijsten, T., Walsh, S., Branicki, W., Wang, S., Ruiz-Linares, A., Spector, T. D., Martin, N. G., Medland, S. E. & Kayser, M., 6 Dec 2017, In : Human Molecular Genetics.

    Research output: Contribution to journalArticle

  4. Association of the resolvin precursor 17-HDHA, but not D-or E-series resolvins, with heat pain sensitivity and osteoarthritis pain in humans

    Valdes, A. M., Ravipati, S., Menni, C., Abhishek, A., Metrustry, S., Harris, J., Nessa, A., Williams, F. M. K., Spector, T. D., Doherty, M., Chapman, V. & Barrett, D. A., 1 Dec 2017, In : Scientific Reports. 7, 1, 10748.

    Research output: Contribution to journalArticle

  5. CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits

    Macé, A., Tuke, M. A., Deelen, P., Kristiansson, K., Mattsson, H., Nõukas, M., Sapkota, Y., Schick, U., Porcu, E., Rüeger, S., McDaid, A. F., Porteous, D., Winkler, T. W., Salvi, E., Shrine, N., Liu, X., Ang, W. Q., Zhang, W., Feitosa, M. F., Venturini, C. & 86 others, Van Der Most, P. J., Rosengren, A., Wood, A. R., Beaumont, R. N., Jones, S. E., Ruth, K. S., Yaghootkar, H., Tyrrell, J., Havulinna, A. S., Boers, H., Mägi, R., Kriebel, J., Müller-Nurasyid, M., Perola, M., Nieminen, M., Lokki, M. L., Kähönen, M., Viikari, J. S., Geller, F., Lahti, J., Palotie, A., Koponen, P., Lundqvist, A., Rissanen, H., Bottinger, E. P., Afaq, S., Wojczynski, M. K., Lenzini, P., Nolte, I. M., Sparsø, T., Schupf, N., Christensen, K., Perls, T. T., Newman, A. B., Werge, T., Snieder, H., Spector, T. D., Chambers, J. C., Koskinen, S., Melbye, M., Raitakari, O. T., Lehtimäki, T., Tobin, M. D., Wain, L. V., Sinisalo, J., Peters, A., Meitinger, T., Martin, N. G., Wray, N. R., Montgomery, G. W., Medland, S. E., Swertz, M. A., Vartiainen, E., Borodulin, K., Männistö, S., Murray, A., Bochud, M., Jacquemont, S., Rivadeneira, F., Hansen, T. F., Oldehinkel, A. J., Mangino, M., Province, M. A., Deloukas, P., Kooner, J. S., Freathy, R. M., Pennell, C., Feenstra, B., Strachan, D. P., Lettre, G., Hirschhorn, J., Cusi, D., Heid, I. M., Hayward, C., Männik, K., Beckmann, J. S., Loos, R. J. F., Nyholt, D. R., Metspalu, A., Eriksson, J. G., Weedon, M. N., Salomaa, V., Franke, L., Reymond, A., Frayling, T. M. & Kutalik, Z., 1 Dec 2017, In : Nature Communications. 8, 1, 744.

    Research output: Contribution to journalArticle

  6. Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood

    Lukowski, S. W., Lloyd-Jones, L. R., Holloway, A., Kirsten, H., Hemani, G., Yang, J., Small, K., Zhao, J., Metspalu, A., Dermitzakis, E. T., Gibson, G., Spector, T. D., Thiery, J., Scholz, M., Montgomery, G. W., Esko, T., Visscher, P. M. & Powell, J. E., 1 Dec 2017, In : Nature Communications. 8, 1, 483.

    Research output: Contribution to journalArticle

  7. Hippurate as a metabolomic marker of gut microbiome diversity: Modulation by diet and relationship to metabolic syndrome

    Pallister, T., Jackson, M. A., Martin, T. C., Zierer, J., Jennings, A., Mohney, R. P., MacGregor, A., Steves, C. J., Cassidy, A., Spector, T. D. & Menni, C., 1 Dec 2017, In : Scientific Reports. 7, 1, 13670.

    Research output: Contribution to journalArticle

  8. Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infants

    Krishnan, M. L., Van Steenwinckel, J., Schang, A., Yan, J., Arnadottir, J., Le Charpentier, T., Csaba, Z., Dournaud, P., Cipriani, S., Auvynet, C., Titomanlio, L., Pansiot, J., Ball, G., Boardman, J. P., Walley, A. J., Saxena, A., Mirza, G., Fleiss, B., Edwards, A. D., Petretto, E. & 1 others, Gressens, P., 1 Dec 2017, In : Nature Communications. 8, 1

    Research output: Contribution to journalArticle

  9. Predicting causal variants affecting expression by using whole-genome sequencing and RNA-seq from multiple human tissues

    Brown, A. A., Viñuela, A., Delaneau, O., Spector, T. D., Small, K. S. & Dermitzakis, E. T., 1 Dec 2017, In : Nature Genetics. 49, 12, p. 1747-1751

    Research output: Contribution to journalLetter

  10. A Comparison of Heritability Estimates by Classical Twin Modeling and Based on Genome-Wide Genetic Relatedness for Cardiac Conduction Traits

    Nolte, I. M., Jansweijer, J. A., Riese, H., Asselbergs, F. W., van der Harst, P., Spector, T. D., Pinto, Y. M., Snieder, H. & Jamshidi, Y., Dec 2017, In : TWIN RESEARCH AND HUMAN GENETICS. p. 1-10 10 p.

    Research output: Contribution to journalArticle

  11. Exome-wide association study of plasma lipids in >300,000 individuals

    Liu, D. J., Peloso, G. M., Yu, H., Butterworth, A. S., Wang, X., Mahajan, A., Saleheen, D., Emdin, C., Alam, D., Alves, A. C., Amouyel, P., Di Angelantonio, E., Arveiler, D., Assimes, T. L., Auer, P. L., Baber, U., Ballantyne, C. M., Bang, L. E., Benn, M., Bis, J. C. & 31 others, Boehnke, M., Boerwinkle, E., Bork-Jensen, J., Bottinger, E. P., Brandslund, I., Brown, M., Busonero, F., Caulfield, M. J., Chambers, J. C., Chasman, D. I., Chen, Y. E., Chen, Y-D. I., Chowdhury, R., Christensen, C., Chu, A. Y., Connell, J. M., Cucca, F., Cupples, L. A., Damrauer, S. M., Davies, G., Deary, I. J., Dedoussis, G., Denny, J. C., Dominiczak, A., Dubé, M-P., Ebeling, T., Eiriksdottir, G., Esko, T., Small, K. S., Spector, T. D. & Charge Diabetes Working Group, Dec 2017, In : Nature Genetics. 49, 12, p. 1758-1766 9 p.

    Research output: Contribution to journalLetter

  12. Predicting brain age with deep learning from raw imaging data results in a reliable and heritable biomarker

    Cole, J. H., Poudel, R. P. K., Tsagkrasoulis, D., Caan, M. W. A., Steves, C., Spector, T. D. & Montana, G., Dec 2017, In : NeuroImage. 163, p. 115-124

    Research output: Contribution to journalArticle

  13. DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation

    Richard, M. A., Huan, T., Ligthart, S., Gondalia, R., Jhun, M. A., Brody, J. A., Irvin, M. R., Marioni, R., Shen, J., Tsai, P-C., Montasser, M. E., Jia, Y., Syme, C., Salfati, E. L., Boerwinkle, E., Guan, W., Mosley, T. H., Bressler, J., Morrison, A. C., Liu, C. & 31 others, Mendelson, M. M., Uitterlinden, A. G., van Meurs, J. B., Franco, O. H., Zhang, G., Li, Y., Stewart, J. D., Bis, J. C., Psaty, B. M., Chen, Y-D. I., Kardia, S. L. R., Zhao, W., Turner, S. T., Absher, D., Aslibekyan, S., Starr, J. M., McRae, A. F., Hou, L., Just, A. C., Schwartz, J. D., Vokonas, P. S., Menni, C., Spector, T. D., Shuldiner, A., Damcott, C. M., Rotter, J. I., Palmas, W., Liu, Y., Paus, T., Bell, J. T. & BIOS Consortium, 30 Nov 2017, In : American Journal of Human Genetics.

    Research output: Contribution to journalArticle

  14. Socio-demographic and cardiovascular disease risk factors associated with dementia: Results of a cross-sectional study from Lebanon

    Chaaya, M., Phung, K., Atweh, S., El Asmar, K., Karam, G., Khoury, R. M., Ghandour, L., Ghusn, H., Assaad, S., Prince, M. & Waldemar, G., 24 Nov 2017, In : Preventive Medicine Reports. 9, p. 1-5

    Research output: Contribution to journalArticle

  15. The prevalence of dementia in a Portuguese community sample: A 10/66 Dementia Research Group study

    Gonçalves-Pereira, M., Cardoso, A., Verdelho, A., Alves da Silva, J., Caldas De Almeida, M., Fernandes, A., Raminhos, C., Ferri, C. P., Prina, A. M., Prince, M. & Xavier, M., 7 Nov 2017, In : BMC Geriatrics . 17, 1, 261.

    Research output: Contribution to journalArticle

  16. Epigenetic discrimination of identical twins from blood under the forensic scenario

    Vidaki, A., López, C. D., Carnero-Montoro, E., Ralf, A., Ward, K., Spector, T., Bell, J. T. & Kayser, M., Nov 2017, In : Forensic Science International-Genetics. 31, p. 67-80 14 p.

    Research output: Contribution to journalArticle

  17. Prevalence and correlates of traumatic brain injury (TBI) in older adults: results from the Well-being of the Singapore Elderly (WiSE) study

    Cetty, L., Abdin, E., Vaingankar, J. A., Jeyagurunathan, A., Chua, B. Y., Picco, L., Prince, M., Chong, S. A. & Subramaniam, M., Nov 2017, In : International psychogeriatrics / IPA. p. 1899-1907 9 p.

    Research output: Contribution to journalArticle

  18. IgG glycosylation and DNA methylation are interconnected with smoking

    Wahl, A., Kasela, S., Monotoro, E. C., van Iterson, M., Štambuk, J., Sharma, S., van den Akker, E., Klaric, L., Benedetti, E., Razdorov, G., Trbojević-Akmačić, I., Vučković, F., Ugrina, I., Beekman, M., Deelen, J., van Heemst, D., Heijmans, B. T., Consortium, B. I. O. S., Wuhrer, M., Plomp, R. & 14 others, Keser, T., Šimurina, M., Pavić, T., Gudelj, I., Krištić, J., Grallert, H., Kunze, S., Peters, A., Bell, J. T., Spector, T. D., Milani, L., Eline Slagboom, P., Lauc, G. & Gieger, C., 18 Oct 2017, In : BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS. 1862, 3, p. 637-648

    Research output: Contribution to journalArticle

  19. Neuropsychiatric symptoms as risk factors of dementia in a Mexican population: A 10/66 Dementia Research Group study

    Acosta, I., Borges, G., Aguirre-Hernandez, R., Sosa, A. L. & Prince, M., 10 Oct 2017, In : Alzheimer's & Dementia.

    Research output: Contribution to journalArticle

  20. Dementia in sub-Saharan Africa: challenges and opportunities

    Guerchet, M. M., Mayston, R., Lloyd-Sherlock, P., Prince, M. J., Aboderin, I., Akinyemi, R., Paddick, S-M., Wimo, A., Amoakoh-Coleman, M., Uwakwe, R. & Ezeah, P., 28 Sep 2017, London: Alzheimer's Disease International. 70 p.

    Research output: Book/ReportCommissioned report

  21. Differential DNA Methylation in Monozygotic Twins Discordant for Female Sexual Functioning

    Burri, A., Leupin, M., Spector, T. & Marinova, Z., 28 Sep 2017, In : JOURNAL OF SEXUAL MEDICINE. 14, 11, p. 1357-1364

    Research output: Contribution to journalArticle

  22. Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation

    Shen, X., Klarić, L., Sharapov, S., Mangino, M., Ning, Z., Wu, D., Trbojević-Akmačić, I., Pučić-Baković, M., Rudan, I., Polašek, O., Hayward, C., Spector, T. D., Wilson, J. F., Lauc, G. & Aulchenko, Y. S., 6 Sep 2017, In : Nature Communications. 8, 1, 447.

    Research output: Contribution to journalArticle

  23. Genome-Wide Association Reveals Pigmentation Genes Play a Role in Skin Aging

    Law, M. H., Medland, S. E., Zhu, G., Yazar, S., Viñuela, A., Wallace, L., Shekar, S. N., Duffy, D. L., Bataille, V., Glass, D., Spector, T. D., Wood, D., Gordon, S. D., Barbour, J. M., Henders, A. K., Hewitt, A. W., Montgomery, G. W., Sturm, R. A., Mackey, D. A., Green, A. C. & 2 others, Martin, N. G. & MacGregor, S., Sep 2017, In : Journal of Investigative Dermatology. 137, 9, p. 1887-1894

    Research output: Contribution to journalArticle

  24. Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

    Wheeler, E., Leong, A., Liu, C-T., Hivert, M-F., Strawbridge, R. J., Podmore, C., Li, M., Yao, J., Sim, X., Hong, J., Chu, A. Y., Zhang, W., Wang, X., Chen, P., Maruthur, N. M., Porneala, B. C., Sharp, S. J., Jia, Y., Kabagambe, E. K., Chang, L-C. & 31 others, Chen, W-M., Elks, C. E., Evans, D. S., Fan, Q., Giulianini, F., Go, M. J., Hottenga, J-J., Hu, Y., Jackson, A. U., Kanoni, S., Kim, Y. J., Kleber, M. E., Ladenvall, C., Lecoeur, C., Lim, S-H., Lu, Y., Mahajan, A., Marzi, C., Nalls, M. A., Navarro, P., Nolte, I. M., Rose, L. M., Rybin, D. V., Sanna, S., Shi, Y., Stram, D. O., Takeuchi, F., Tan, S. P., van der Most, P. J., Spector, T. D. & EPIC-CVD Consortium, Sep 2017, In : PL o S Medicine. 14, 9, p. e1002383

    Research output: Contribution to journalArticle

  25. Genetic and environmental influences on stability and change in baseline levels of C-reactive protein: A longitudinal twin study

    Sas, A. A., Vaez, A., Jamshidi, Y., Nolte, I. M., Kamali, Z., Spector, T. D., Riese, H. & Snieder, H., 31 Aug 2017, In : Atherosclerosis.

    Research output: Contribution to journalArticle

  26. Genome-wide association and functional studies identify a role for matrix Gla protein in osteoarthritis of the hand

    Hollander, W. D., Boer, C. G., Hart, D. J., Yau, M. S., Ramos, Y. F. M., Metrustry, S., Broer, L., Deelen, J., Cupples, L. A., Rivadeneira, F., Kloppenburg, M., Peters, M., Spector, T. D., Hofman, A., Slagboom, P. E., Nelissen, R. G. H. H., Uitterlinden, A. G., Felson, D. T., Valdes, A. M., Meulenbelt, I. & 1 others, van Meurs, J. J. B., 30 Aug 2017, In : Annals of the rheumatic diseases. 76, 12, p. 2046-2053

    Research output: Contribution to journalArticle

  27. Reactive astrocyte COX2-PGE2 production inhibits oligodendrocyte maturation in neonatal white matter injury

    Shiow, L. R., Favrais, G., Schirmer, L., Schang, A-L., Cipriani, S., Andres, C., Wright, J. N., Nobuta, H., Fleiss, B., Gressens, P. & Rowitch, D. H., 30 Aug 2017, In : Glia.

    Research output: Contribution to journalArticle

  28. A journey without maps—Understanding the costs of caring for dependent older people in Nigeria, China, Mexico and Peru

    Mayston, R., Lloyd-sherlock, P., Gallardo, S., Wang, H., Huang, Y., Montes De Oca, V., Ezeah, P., Guerra, M., Sosa, A. L., Liu, Z., Uwakwe, R., Guerchet, M. M., Prince, M. & Larson, B. A. (ed.), 7 Aug 2017, In : PL o S One . 12, 8, e0182360.

    Research output: Contribution to journalArticle

  29. Differences in genetic and environmental variation in adult BMI by sex, age, time period, and region: An individual-based pooled analysis of 40 twin cohorts

    Silventoinen, K., Jelenkovic, A., Sund, R., Yokoyama, Y., Hur, Y. M., Cozen, W., Hwang, A. E., Mack, T. M., Honda, C., Inui, F., Iwatani, Y., Watanabe, M., Tomizawa, R., Pietilainen, K. H., Rissanen, A., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Tan, Q. & 82 others, Zhang, D., Pang, Z., Piirtola, M., Aaltonen, S., Oncel, S. Y., Aliev, F., Rebato, E., Hjelmborg, J. B., Christensen, K., Skytthe, A., Kyvik, K. O., Silberg, J. L., Eaves, L. J., Cutler, T. L., Ordonana, J. R., Sanchez-Romera, J. F., Colodro-Conde, L., Song, Y. M., Yang, S., Lee, K., Franz, C. E., Kremen, W. S., Lyons, M. J., Busjahn, A., Nelson, T. L., Whitfield, K. E., Kandler, C., Jang, K. L., Gatz, M., Butler, D. A., Stazi, M. A., Fagnani, C., D'Ippolito, C., Duncan, G. E., Buchwald, D., Martin, N. G., Medland, S. E., Montgomery, G. W., Jeong, H. U., Swan, G. E., Krasnow, R., Magnusson, P. K. E., Pedersen, N. L., Dahl Aslan, A. K., McAdams, T. A., Eley, T. C., Gregory, A. M., Tynelius, P., Baker, L. A., Tuvblad, C., Bayasgalan, G., Narandalai, D., Spector, T. D., Mangino, M., Lachance, G., Burt, S. A., Klump, K. L., Harris, J. R., Brandt, I., Nilsen, T. S., Krueger, R. F., McGue, M., Pahlen, S., Corley, R. P., Huibregtse, B. M., Bartels, M., Van Beijsterveldt, C. E. M., Willemsen, G., Goldberg, J. H., Rasmussen, F., Tarnoki, A. D., Tarnoki, D. L., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Hopper, J. L., Sung, J., Maes, H. H., Turkheimer, E., Boomsma, D. I., Sørensen, T. I. A. & Kaprio, J., 1 Aug 2017, In : American Journal of Clinical Nutrition. 106, 2, p. 457-466 10 p.

    Research output: Contribution to journalArticle

  30. Inference and quantification of peptidoforms in large sample cohorts by SWATH-MS

    Rosenberger, G., Liu, Y., Röst, H. L., Ludwig, C., Buil, A., Bensimon, A., Soste, M., Spector, T. D., Dermitzakis, E. T., Collins, B. C., Malmström, L. & Aebersold, R., 1 Aug 2017, In : Nature Biotechnology. 35, 8, p. 781-788 8 p.

    Research output: Contribution to journalArticle

  31. Pain in knee osteoarthritis is associated with variation in the neurokinin 1/substance P receptor (TACR1) gene

    Warner, S. C., Walsh, D. A., Laslett, L. L., Maciewicz, R. A., Soni, A., Hart, D. J., Zhang, W., Muir, K. R., Dennison, E. M., Leaverton, P., Rampersaud, E., Cooper, C., Spector, T. D., Cicuttini, F. M., Arden, N. K., Jones, G., Doherty, M. & Valdes, A. M., Aug 2017, In : European journal of pain (London, England). p. 1277-1284

    Research output: Contribution to journalArticle

  32. Metabolomic Profiling of Long-Term Weight Change: Role of Oxidative Stress and Urate Levels in Weight Gain

    Menni, C., Migaud, M., Kastenmüller, G., Pallister, T., Zierer, J., Peters, A., Mohney, R. P., Spector, T. D., Bagnardi, V., Gieger, C., Moore, S. C. & Valdes, A. M., 31 Jul 2017, In : Obesity. 25, 9, p. 1618-1624

    Research output: Contribution to journalArticle

  33. Progress on dementia: leaving no one behind

    Prince, M., 20 Jul 2017, In : Lancet.

    Research output: Contribution to journalArticle

  34. Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

    Zillikens, M. C., Demissie, S., Hsu, Y-H., Yerges-Armstrong, L. M., Chou, W-C., Stolk, L., Livshits, G., Broer, L., Johnson, T., Koller, D. L., Kutalik, Z., Luan, J., Malkin, I., Ried, J. S., Smith, A. V., Thorleifsson, G., Vandenput, L., Hua Zhao, J., Zhang, W., Aghdassi, A. & 173 others, Åkesson, K., Amin, N., Baier, L. J., Barroso, I., Bennett, D. A., Bertram, L., Biffar, R., Bochud, M., Boehnke, M., Borecki, I. B., Buchman, A. S., Byberg, L., Campbell, H., Campos Obanda, N., Cauley, J. A., Cawthon, P. M., Cederberg, H., Chen, Z., Cho, N. H., Jin Choi, H., Claussnitzer, M., Collins, F., Cummings, S. R., De Jager, P. L., Demuth, I., Dhonukshe-Rutten, R. A. M., Diatchenko, L., Eiriksdottir, G., Enneman, A. W., Erdos, M., Eriksson, J. G., Eriksson, J., Estrada, K., Evans, D. S., Feitosa, M. F., Fu, M., Garcia, M., Gieger, C., Girke, T., Glazer, N. L., Grallert, H., Grewal, J., Han, B-G., Hanson, R. L., Hayward, C., Hofman, A., Hoffman, E. P., Homuth, G., Hsueh, W-C., Hubal, M. J., Hubbard, A., Huffman, K. M., Husted, L. B., Illig, T., Ingelsson, E., Ittermann, T., Jansson, J-O., Jordan, J. M., Jula, A., Karlsson, M., Khaw, K-T., Kilpeläinen, T. O., Klopp, N., Kloth, J. S. L., Koistinen, H. A., Kraus, W. E., Kritchevsky, S., Kuulasmaa, T., Kuusisto, J., Laakso, M., Lahti, J., Lang, T., Langdahl, B. L., Launer, L. J., Lee, J-Y., Lerch, M. M., Lewis, J. R., Lind, L., Lindgren, C., Liu, Y., Liu, T., Liu, Y., Ljunggren, Ö., Lorentzon, M., Luben, R. N., Maixner, W., McGuigan, F. E., Medina-Gomez, C., Meitinger, T., Melhus, H., Mellström, D., Melov, S., Michaëlsson, K., Mitchell, B. D., Morris, A. P., Mosekilde, L., Newman, A., Nielson, C. M., O'Connell, J. R., Oostra, B. A., Orwoll, E. S., Palotie, A., Parker, S. C. J., Peacock, M., Perola, M., Peters, A., Polasek, O., Prince, R. L., Räikkönen, K., Ralston, S. H., Ripatti, S., Robbins, J. A., Rotter, J. I., Rudan, I., Salomaa, V., Satterfield, S., Schadt, E. E., Schipf, S., Scott, L., Sehmi, J., Shen, J., Soo Shin, C., Sigurdsson, G., Smith, S., Soranzo, N., Stančáková, A., Steinhagen-Thiessen, E., Streeten, E. A., Styrkarsdottir, U., Swart, K. M. A., Tan, S-T., Tarnopolsky, M. A., Thompson, P., Thomson, C. A., Thorsteinsdottir, U., Tikkanen, E., Tranah, G. J., Tuomilehto, J., van Schoor, N. M., Verma, A., Vollenweider, P., Völzke, H., Wactawski-Wende, J., Walker, M., Weedon, M. N., Welch, R., Wichmann, H-E., Widen, E., Williams, F., Wilson, J. F., Wright, N. C., Xie, W., Yu, L., Zhou, Y., Chambers, J. C., Döring, A., van Duijn, C. M., Econs, M. J., Gudnason, V., Kooner, J. S., Psaty, B. M., Spector, T., Stefansson, K., Rivadeneira, F., Uitterlinden, A. G., Wareham, N. J., Ossowski, V., Waterworth, D., Loos, R. J. F., Karasik, D., Harris, T. B., Ohlsson, C. & Kiel, D. P., 19 Jul 2017, In : Nature Communications. 8, 1, p. 80

    Research output: Contribution to journalArticle

  35. Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation

    Mullin, B. H., Zhao, J. H., Brown, S. J., Perry, J. R. B., Luan, J., Zheng, H-F., Langenberg, C., Dudbridge, F., Scott, R., Wareham, N. J., Spector, T. D., Richards, J. B., Walsh, J. P. & Wilson, S. G., 15 Jul 2017, In : Human Molecular Genetics. 26, 14, p. 2791-2802 12 p.

    Research output: Contribution to journalArticle

  36. Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness

    Willems, S. M., Wright, D. J., Day, F. R., Trajanoska, K., Joshi, P. K., Morris, J. A., Matteini, A. M., Garton, F. C., Grarup, N., Oskolkov, N., Thalamuthu, A., Mangino, M., Liu, J., Demirkan, A., Lek, M., Xu, L., Wang, G., Oldmeadow, C., Gaulton, K. J., Lotta, L. A. & 141 others, Miyamoto-Mikami, E., Rivas, M. A., White, T., Loh, P. R., Aadahl, M., Amin, N., Attia, J. R., Austin, K., Benyamin, B., Brage, S., Cheng, Y. C., Ciȩszczyk, P., Derave, W., Eriksson, K. F., Eynon, N., Linneberg, A., Lucia, A., Massidda, M., Mitchell, B. D., Miyachi, M., Murakami, H., Padmanabhan, S., Pandey, A., Papadimitriou, I., Rajpal, D. K., Sale, C., Schnurr, T. M., Sessa, F., Shrine, N., Tobin, M. D., Varley, I., Wain, L. V., Wray, N. R., Lindgren, C. M., MacArthur, D. G., Waterworth, D. M., McCarthy, M. I., Pedersen, O., Khaw, K. T., Kiel, D. P., Pitsiladis, Y., Fuku, N., Franks, P. W., North, K. N., Van Duijn, C. M., Mather, K. A., Hansen, T., Hansson, O., Spector, T., Murabito, J. M., Richards, J. B., Rivadeneira, F., Langenberg, C., Perry, J. R. B., Wareham, N. J., Scott, R. A., Oei, L., Zheng, H. F., Forgetta, V., Leong, A., Ahmad, O. S., Laurin, C., Mokry, L. E., Ross, S., Elks, C. E., Bowden, J., Warrington, N. M., Murray, A., Ruth, K. S., Tsilidis, K. K., Medina-Gómez, C., Estrada, K., Bis, J. C., Chasman, D. I., Demissie, S., Enneman, A. W., Hsu, Y. H., Ingvarsson, T., Kähönen, M., Kammerer, C., Lacroix, A. Z., Li, G., Liu, C. T., Liu, Y., Lorentzon, M., Mägi, R., Mihailov, E., Milani, L., Moayyeri, A., Nielson, C. M., Sham, P. C., Siggeirsdotir, K., Sigurdsson, G., Stefansson, K., Trompet, S., Thorleifsson, G., Vandenput, L., Van Der Velde, N., Viikari, J., Xiao, S. M., Zhao, J. H., Evans, D. S., Cummings, S. R., Cauley, J., Duncan, E. L., De Groot, L. C. P. G. M., Esko, T., Gudnason, V., Harris, T. B., Jackson, R. D., Jukema, J. W., Ikram, A. M. A., Karasik, D., Kaptoge, S., Kung, A. W. C., Lehtimäki, T., Lyytikäinen, L. P., Lips, P., Luben, R., Metspalu, A., Van Meurs, J. B. J., Minster, R. L., Orwoll, E., Oei, E., Psaty, B. M., Raitakari, O. T., Ralston, S. W., Ridker, P. M., Robbins, J. A., Smith, A. V., Styrkarsdottir, U., Tranah, G. J., Thorstensdottir, U., Uitterlinden, A. G., Zmuda, J., Zillikens, M. C., Ntzani, E. E., Evangelou, E., Ioannidis, J. P. A., Evans, D. M. & Ohlsson, C., 12 Jul 2017, In : Nature Communications. 8, 16015.

    Research output: Contribution to journalArticle

  37. Diagnosis of Dementia by Machine learning methods in Epidemiological studies: a pilot exploratory study from south India

    Bhagyashree, S. I. R., Nagaraj, K., Prince, M., Fall, C. H. D. & Krishna, M., 11 Jul 2017, In : Social Psychiatry and Psychiatric Epidemiology.

    Research output: Contribution to journalArticle

  38. Erratum to: Influence of acquired obesity on coronary vessel wall late gadolinium enhancement in discordant monozygote twins

    Makowski, M. R., Jansen, C. H. P., Ebersberger, U., Schaeffter, T., Razavi, R., Mangino, M., Spector, T. D., Botnar, R. & Greil, G. F., 4 Jul 2017, In : European Radiology. p. 1 1 p.

    Research output: Contribution to journalArticle

  39. Affective responses to sweet products and sweet solution in British and Finnish adults

    Tuorila, H., Keskitalo-Vuokko, K., Perola, M., Spector, T. & Kaprio, J., 1 Jul 2017, In : FOOD QUALITY AND PREFERENCE.

    Research output: Contribution to journalArticle

  40. A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

    Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Viñuela, A., Brown, A. A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J., Im, H. K. & 243 others, Teslovich, T. M., Blackwell, T. W., Bork-Jensen, J., Burtt, N. P., Chen, Y., Green, T., Hartl, C., Kang, H. M., Kumar, A., Ladenvall, C., Ma, C., Moutsianas, L., Pearson, R. D., Perry, J. R. B., Rayner, N. W., Robertson, N. R., Scott, L. J., van de Bunt, M., Eriksson, J. G., Jula, A., Koskinen, S., Lehtimäki, T., Palotie, A., Raitakari, O. T., Jacobs, S. B. R., Wessel, J., Chu, A. Y., Scott, R. A., Goodarzi, M. O., Blancher, C., Buck, G., Buck, D., Chines, P. S., Gabriel, S., Gjesing, A. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, J. M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Trakalo, J., Banks, E., Carey, J., Carneiro, M. O., DePristo, M., Farjoun, Y., Fennell, T., Goldstein, J. I., Grant, G., Hrabé de Angelis, M., Maguire, J., Neale, B. M., Poplin, R., Purcell, S., Schwarzmayr, T., Shakir, K., Smith, J. D., Strom, T. M., Wieland, T., Lindstrom, J., Brandslund, I., Christensen, C., Surdulescu, G. L., Lakka, T. A., Doney, A. S. F., Nilsson, P., Wareham, N. J., Langenberg, C., Varga, T. V., Franks, P. W., Rolandsson, O., Rosengren, A. H., Farook, V. S., Thameem, F., Puppala, S., Kumar, S., Lehman, D. M., Jenkinson, C. P., Curran, J. E., Hale, D. E., Fowler, S. P., Arya, R., DeFronzo, R. A., Abboud, H. E., Syvänen, A-C., Hicks, P. J., Palmer, N. D., Ng, M. C. Y., Bowden, D. W., Freedman, B. I., Esko, T., Mägi, R., Milani, L., Mihailov, E., Metspalu, A., Narisu, N., Kinnunen, L., Bonnycastle, L. L., Swift, A., Pasko, D., Wood, A. R., Fadista, J., Pollin, T. I., Barzilai, N., Atzmon, G., Glaser, B., Thorand, B., Strauch, K., Peters, A., Roden, M., Müller-Nurasyid, M., Liang, L., Kriebel, J., Illig, T., Grallert, H., Gieger, C., Meisinger, C., Lannfelt, L., Musani, S. K., Griswold, M., Taylor, H. A., Wilson, G., Correa, A., Oksa, H., Scott, W. R., Afzal, U., Tan, S-T., Loh, M., Chambers, J. C., Sehmi, J., Kooner, J. S., Lehne, B., Cho, Y. S., Lee, J-Y., Han, B-G., Käräjämäki, A., Qi, Q., Qi, L., Huang, J., Hu, F. B., Melander, O., Orho-Melander, M., Below, J. E., Aguilar, D., Wong, T. Y., Liu, J., Khor, C-C., Chia, K. S., Lim, W. Y., Cheng, C-Y., Chan, E., Tai, E. S., Aung, T., Linneberg, A., Isomaa, B., Meitinger, T., Tuomi, T., Hakaste, L., Kravic, J., Jørgensen, M. E., Lauritzen, T., Deloukas, P., Stirrups, K. E., Owen, K. R., Farmer, A. J., Frayling, T. M., O'Rahilly, S. P., Walker, M., Levy, J. C., Hodgkiss, D., Hattersley, A. T., Kuulasmaa, T., Stančáková, A., Barroso, I., Bharadwaj, D., Chan, J., Chandak, G. R., Daly, M. J., Donnelly, P. J., Ebrahim, S. B., Elliott, P., Fingerlin, T., Froguel, P., Hu, C., Jia, W., Ma, R. C. W., McVean, G., Park, T., Prabhakaran, D., Sandhu, M., Scott, J., Sladek, R., Tandon, N., Teo, Y. Y., Zeggini, E., Watanabe, R. M., Koistinen, H. A., Kesaniemi, Y. A., Uusitupa, M., Spector, T. D., Salomaa, V., Rauramaa, R., Palmer, C. N. A., Prokopenko, I., Morris, A. D., Bergman, R. N., Collins, F. S., Lind, L., Ingelsson, E., Tuomilehto, J., Karpe, F., Groop, L., Jørgensen, T., Hansen, T., Pedersen, O., Kuusisto, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Seielstad, M., Wilson, J. G., Dupuis, J., Ripatti, S., Hanis, C. L., Florez, J. C., Mohlke, K. L., Meigs, J. B., Laakso, M., Morris, A. P., Boehnke, M., Altshuler, D., McCarthy, M. I., Gloyn, A. L. & Lindgren, C. M., Jul 2017, In : Diabetes. 66, 7, p. 2019-2032 14 p.

    Research output: Contribution to journalArticle

  41. Ethnicity, mortality, and severe mental illness – Authors' reply

    Das-Munshi, J., Chang, C-K., Dutta, R., Morgan, C., Nazroo, J., Stewart, R. & Prince, M. J., Jul 2017, In : The Lancet Psychiatry. 4, 7, p. 517-518 2 p.

    Research output: Contribution to journalArticle

  42. MORTALITY AMONG OLDER ADULTS WITH DEMENTIA IN LOW- AND MIDDLE-INCOME COUNTRIES: THE 10/66 DEMENTIA RESEARCH GROUP COHORT STUDIES: 2017 Abstract Supplement

    Piovezan, R. D., Arias, N., Acosta, D., Galduroz, J. C., de Almeida Machado, D., Laks, J., Prince, M. J. & Ferri, C., Jul 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P197

    Research output: Contribution to journalMeeting abstract

  43. Persistently Altered Metabolic Phenotype following Perinatal Excitotoxic Brain Injury

    Blaise, B. J., Schwendimann, L., Chhor, V., Degos, V., Hodson, M. P., Dallmann, G., Keller, M., Gressens, P. & Fleiss, B., Jul 2017, In : Developmental Neuroscience. 39, p. 182-191 10 p.

    Research output: Contribution to journalArticle

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