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Research Outputs

  1. 2017
  2. Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation

    Nabeebaccus, A. A., Zoccarato, A., Hafstad, A. D., Santos, C. X., Aasum, E., Brewer, A. C., Zhang, M., Beretta, M., Yin, X., West, J. A., Schröder, K., Griffin, J. L., Eykyn, T. R., Abel, E. D., Mayr, M. & Shah, A. M., 21 Dec 2017, In : JCI Insight. 2, 24

    Research output: Contribution to journalArticle

  3. Disorder-Specific and Shared Brain Abnormalities During Vigilance in Autism and Obsessive-Compulsive Disorder

    Carlisi, C. O., Norman, L., Murphy, C., Christakou, A., Chantiluke, K., Giampietro, V., Simmons, A., Brammer, M., Murphy, D. G., AIMS Consortium, Mataix-Cols, D. & Rubia, K., Nov 2017, In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 2, 8, p. 644-654

    Research output: Contribution to journalArticle

  4. Cortical responses before six months of life associate with later autism

    Lloyd-Fox, S., Blasi, A., Pasco, G., Gliga, T., Jones, E., Murphy, D. G., Elwell, C. E., Charman, T. & Johnson, M., 23 Oct 2017, In : European Journal of Neuroscience.

    Research output: Contribution to journalArticle

  5. Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity

    Coats, B. R., Schoenfelt, K. Q., Barbosa-Lorenzi, V. C., Peris, E., Cui, C., Hoffman, A., Zhou, G., Fernandez, S., Zhai, L., Hall, B. A., Haka, A. S., Shah, A. M., Reardon, C. A., Brady, M. J., Rhodes, C. J., Maxfield, F. R. & Becker, L., 26 Sep 2017, In : Cell Reports. 20, 13, p. 3149-3161 13 p.

    Research output: Contribution to journalArticle

  6. Glutamatergic Agents in the Treatment of Compulsivity and Impulsivity in Child and Adolescent Psychiatry: a Systematic Review of the Literature

    Mechler, K., Häge, A., Schweinfurth, N., Glennon, J. C., Dijkhuizen, R. M., Murphy, D., Durston, S., Williams, S., Buitelaar, J. K., Banaschewski, T., Dittmann, R. W. & Tactics Consortium, T., 18 Sep 2017, In : ZEITSCHRIFT FUR KINDER UND JUGENDPSYCHIATRIE UND PSYCHOTHERAPIE. p. 246-263

    Research output: Contribution to journalArticle

  7. Mother-infant interactions and regional brain volumes in infancy: an MRI study

    Sethna, V., Pote, I., Wang, S., Gudbrandsen, M., Blasi, A., McCusker, C., Daly, E., Perry, E., Adams, K. P. H., Kuklisova-Murgasova, M., Busuulwa, P., Lloyd-Fox, S., Murray, L., Johnson, M. H., Williams, S. C. R., Murphy, D. G. M., Craig, M. C. & McAlonan, G. M., Jul 2017, In : Brain structure & function. 222, 5, p. 2379-2388

    Research output: Contribution to journalArticle

  8. The EU-AIMS Longitudinal European Autism Project (LEAP): Clinical characterisation

    Charman, T., Loth, E., Tillmann, J., Crawley, D., Wooldridge, C., Goyard, D., Ahmad, J., Auyeung, B., Ambrosino, S., Banaschewski, T., Baron-Cohen, S., Baumeister, S., Beckmann, C., Bölte, S., Bourgeron, T., Bours, C., Brammer, M., Brandeis, D., Brogna, C., De Bruijn, Y. & 45 others, Chakrabarti, B., Cornelissen, I., Dell' Acqua, F., Dumas, G., Durston, S., Ecker, C., Faulkner, J., Frouin, V., Garcés, P., Ham, L., Hayward, H., Hipp, J., Holt, R. J., Isaksson, J., Johnson, M. H., Jones, E. J. H., Kundu, P., Lai, M. C., D'ardhuy, X. L., Lombardo, M. V., Lythgoe, D. J., Mandl, R., Mason, L., Meyer-Lindenberg, A., Moessnang, C., Mueller, N., O'Dwyer, L., Oldehinkel, M., Oranje, B., Pandina, G., Persico, A. M., Ruggeri, B., Ruigrok, A. N. V., Sabet, J., Sacco, R., Cáceres, A. S. J., Simonoff, E., Toro, R., Tost, H., Waldman, J., Williams, S. C. R., Zwiers, M. P., Spooren, W., Murphy, D. G. M. & Buitelaar, J. K., 23 Jun 2017, In : Molecular Autism. 8, 1, 27.

    Research output: Contribution to journalArticle

  9. The EU-AIMS Longitudinal European Autism Project (LEAP): Design and methodologies to identify and validate stratification biomarkers for autism spectrum disorders

    Loth, E., Charman, T., Mason, L., Tillmann, J., Jones, E. J. H., Wooldridge, C., Ahmad, J., Auyeung, B., Brogna, C., Ambrosino, S., Banaschewski, T., Baron-Cohen, S., Baumeister, S., Beckmann, C., Brammer, M., Brandeis, D., Bölte, S., Bourgeron, T., Bours, C., De Bruijn, Y. & 45 others, Chakrabarti, B., Crawley, D., Cornelissen, I., Dell' Acqua, F., Dumas, G., Durston, S., Ecker, C., Faulkner, J., Frouin, V., Garces, P., Goyard, D., Hayward, H., Ham, L. M., Hipp, J., Holt, R. J., Johnson, M. H., Isaksson, J., Kundu, P., Lai, M. C., D'ardhuy, X. L., Lombardo, M. V., Lythgoe, D. J., Mandl, R., Meyer-Lindenberg, A., Moessnang, C., Mueller, N., O'Dwyer, L., Oldehinkel, M., Oranje, B., Pandina, G., Persico, A. M., Ruigrok, A. N. V., Ruggeri, B., Sabet, J., Sacco, R., Cáceres, A. S. J., Simonoff, E., Toro, R., Tost, H., Waldman, J., Williams, S. C. R., Zwiers, M. P., Spooren, W., Murphy, D. G. M. & Buitelaar, J. K., 23 Jun 2017, In : Molecular Autism. 8, 1, 24.

    Research output: Contribution to journalArticle

  10. Decoding NADPH Oxidase 4 Expression in Human Tumors

    Meitzler, J. L., Makhlouf, H. R., Antony, S., Wu, Y., Butcher, D., Jiang, G., Juhasz, A., Lu, J., Dahan, I., Jansen-Dürr, P., Pircher, H., Shah, A. M., Roy, K. & Doroshow, J. H., 26 May 2017, In : Redox Biology. 13, p. 182–195

    Research output: Contribution to journalArticle

  11. Shifting brain inhibitory balance and connectivity of the prefrontal cortex of adults with autism spectrum disorder

    Ajram, L. A., Horder, J., Mendez, M. A., Galanopoulos, A., Brennan, L. P., Wichers, R. H., Robertson, D. M., Murphy, C. M., Zinkstok, J., Ivin, G., Heasman, M., Meek, D., Tricklebank, M. D., Barker, G. J., Lythgoe, D. J., Edden, R. A. E., Williams, S. C., Murphy, D. G. M. & McAlonan, G. M., 23 May 2017, In : Translational psychiatry. 7, 5, e1137.

    Research output: Contribution to journalArticle

  12. Family therapy for autism spectrum disorders

    Spain, D., Sin, J., Paliokosta, E., Furuta, M., Prunty, J. E., Chalder, T., Murphy, D. G. & Happe, F. G., 16 May 2017, In : Cochrane Database of Systematic Reviews. 2017, 5, p. 1-35 35 p., CD011894.

    Research output: Contribution to journalArticle

  13. Blood Pressure in Healthy Humans is Regulated by Neuronal NO Synthase

    Shabeeh, H., Khan, S., Jiang, B., Brett, S., Melikian, N., Casadei, B., Chowienczyk, P. J. & Shah, A. M., 1 May 2017, In : Hypertension. 69, 5, p. 970-976 7 p.

    Research output: Contribution to journalArticle

  14. Association Between the Probability of Autism Spectrum Disorder and Normative Sex-Related Phenotypic Diversity in Brain Structure

    Ecker, C., Andrews, D. S., Gudbrandsen, C. M., Marquand, A. F., Ginestet, C. E., Daly, E. M., Murphy, C., Lai, M-C., Lombardo, M. V., Ruigrok, A. N. V., Bullmore, E. T., Suckling, J., Williams, S. C. R., Baron-Cohen, S., Craig, M. C., Murphy, D. G. M. & Medical Research Council Autism Imaging Multicentre Study (MRC AIMS) Consortium, 1 Apr 2017, In : JAMA Psychiatry. 74, 4, p. 329-338 10 p.

    Research output: Contribution to journalArticle

  15. Distinct Regulatory Effects of Myeloid Cell and Endothelial Cell Nox2 on Blood Pressure

    Sag, C. M., Schnelle, M., Zhang, J., Murdoch, C. E., Kossmann, S., Protti, A., Santos, C. X. C., Sawyer, G. J., Zhang, X., Mongue-Din, H., Richards, D. A., Brewer, A. C., Prysyazhna, O., Maier, L. S., Wenzel, P., Eaton, P. J. & Shah, A. M., 28 Mar 2017, In : Circulation (Baltimore).

    Research output: Contribution to journalArticle

  16. ECHOCARDIOGRAPHIC ESTIMATION OF MEAN PULMONARY ARTERY PRESSURE: A COMPARISON OF DIFFERENT APPROACHES TO PREDICT PULMONARY HYPERTENSION

    Seidler, T., Hellenkamp, K., Unsöld, B., Mushemi-Blake, S., Shah, A. & Hasenfuss, G., 21 Mar 2017, In : Journal of the American College of Cardiology. 69, 11, Supplement, p. 1889 1 p.

    Research output: Contribution to journalArticle

  17. Selective Enhancement of Insulin Sensitivity in the Endothelium in Vivo Reveals a Novel Proatherosclerotic Signaling Loop

    Viswambharan, H., Yuldasheva, N. Y., Sengupta, A., Imrie, H., Gage, M. C., Haywood, N., Walker, A. M. N., Skromna, A., Makova, N., Galloway, S., Shah, P., Sukumar, P., Porter, K. E., Grant, P. J., Shah, A., Santos, C. X., Li, J., Beech, D. J., Wheatcroft, S. B., Cubbon, R. M. & 1 others, Kearney, M. T., 3 Mar 2017, In : Circulation Research. 120, 5, p. 784-798 15 p.

    Research output: Contribution to journalArticle

  18. On the brain structure heterogeneity of autism: Parsing out acquisition site effects with significance-weighted principal component analysis

    Martinez-Murcia, F. J., Lai, M. C., Górriz, J. M., Ramírez, J., Young, A. M. H., Deoni, S. C. L., Ecker, C., Lombardo, M. V., Baron-Cohen, S., Murphy, D. G. M., Bullmore, E. T., Suckling, J., Bailey, A. J., Baron-Cohen, S., Bolton, P. F., Bullmore, E. T., Carrington, S., Catani, M., Chakrabarti, B., Craig, M. C. & 22 others, Daly, E. M., Deoni, S. C. L., Ecker, C., Happé, F., Henty, J., Jezzard, P., Johnston, P., Jones, D. K., Lai, M. C., Lombardo, M. V., Madden, A., Mullins, D., Murphy, C. M., Murphy, D. G. M., Pasco, G., Ruigrok, A. N. V., Sadek, S. A., Spain, D., Stewart, R., Suckling, J., Wheelwright, S. J. & Williams, S. C., 1 Mar 2017, In : Human Brain Mapping. 38, 3, p. 1208-1223 16 p.

    Research output: Contribution to journalArticle

  19. Hypoxia induces heart regeneration in adult mice

    Nakada, Y., Canseco, D. C., Thet, S., Abdisalaam, S., Asaithamby, A., Xavier Da Costa Dos Santos, C. S., Shah, A. M., Zhang, H., Faber, J. E., Kinter, M. T., Szweda, L. I., Xing, C., Hu, Z., Deberardinis, R. J., Schiattarella, G., Hill, J. A., Oz, O., Lu, Z., Zhang, C. C., Kimura, W. & 1 others, Sadek, H. A., 12 Jan 2017, In : NATURE. 541, 7636, p. 222-227 6 p.

    Research output: Contribution to journalArticle

  20. In Vivo Evidence of Reduced Integrity of the Gray-White Matter Boundary in Autism Spectrum Disorder

    Andrews, D. S., Avino, T. A., Gudbrandsen, M., Daly, E., Marquand, A., Murphy, C. M., Lai, M-C., Lombardo, M. V., Ruigrok, A. N. V., Williams, S. C., Bullmore, E. T., The Mrc Aims Consortium, U., Suckling, J., Baron-Cohen, S., Craig, M. C., Murphy, D. G. M. & Ecker, C., 4 Jan 2017, In : Cerebral cortex (New York, N.Y. : 1991). 11 p.

    Research output: Contribution to journalArticle

  21. PHD2 is a regulator for glycolytic reprogramming in macrophages

    Guentsch, A., Beneke, A., Swain, L., Farhat, K., Nagarajan, S., Wielockx, B., Raithatha, K., Dudek, J., Rehling, P., Zieseniss, A., Jatho, A., Chong, M., Santos, C. X. C., Shah, A. M. & Katschinski, D. M., Jan 2017, In : Molecular and Cellular Biology. 37, 1, e00236-16.

    Research output: Contribution to journalArticle

  22. Neuroanatomy and neuropathology of autism spectrum disorder in humans

    Ecker, C., Schmeisser, M. J., Loth, E. & Murphy, D. G., 2017, Advances in Anatomy Embryology and Cell Biology. Springer Verlag, Vol. 224. p. 27-48 22 p. (Advances in Anatomy Embryology and Cell Biology; vol. 224).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  23. 2016
  24. Social anxiety in adult males with autism spectrum disorders

    Spain, D., Happé, F., Johnston, P., Campbell, M., Sin, J., Daly, E., Ecker, C., Anson, M., Chaplin, E., Glaser, K., Mendez, A., Lovell, K., Murphy, D. G., Johnston, P., Campbell, M., Anson, M., Lovell, K., MRC AIMS Consortium, AIMS. C. & Chaplin, E., Dec 2016, In : Research In Autism Spectrum Disorders. 32, p. 13-23 11 p.

    Research output: Contribution to journalArticle

  25. Toll-like receptor 9 prevents cardiac rupture after myocardial infarction in mice independently of inflammation

    Omiya, S., Omori, Y., Taneike, M., Protti, A., Yamaguchi, O., Akira, S., Shah, A., Nishida, K. & Otsu, K., Dec 2016, In : American Journal of Physiology (Heart and Circulatory Physiology). 311, 6, p. H1485-H1497

    Research output: Contribution to journalArticle

  26. Unsupervised data-driven stratification of mentalizing heterogeneity in autism

    Lombardo, M. V., Lai, M. C., Auyeung, B., Holt, R. J., Allison, C., Smith, P., Chakrabarti, B., Ruigrok, A. N. V., Suckling, J., Bullmore, E. T., MRC AIMS Consortium: Anthony J. Bailey, Simon Baron-Cohen, Patrick F. Bolton, Edward T. Bullmore, Sarah Carrington, Marco Catani, Bhismadev Chakrabarti, Michael C. Craig, Eileen M. Daly, Sean C. L. Deoni, Christine Ecker, Francesca Happé, Julian Henty, Peter Jezzard, Patrick Johnston, Derek K. Jones, Meng-Chuan Lai, Michael V. Lombardo, Anya Madden, Diane Mullins, Clodagh M. Murphy, Declan G. M. Murphy, Greg Pasco, Amber N. V. Ruigrok, Susan A. Sadek, Debbie Spain, Rose Stewart, John Suckling, Sally J. Wheelwright, Steven C. Williams & C. Ellie Wilson, Ecker, C., Craig, M. C., Murphy, D. G. M., Happe, F., Baron-Cohen, S., Baron-Cohen, S. & Bolton, P. F., 18 Oct 2016, In : Scientific Reports. 6, 35333 .

    Research output: Contribution to journalArticle

  27. Redox Imaging Using Cardiac Myocyte-Specific Transgenic Biosensor Mice

    Swain, L., Kesemeyer, A., Meyer-Roxlau, S., Vettel, C., Zieseniss, A., Güntsch, A., Jatho, A., Becker, A., Nanadikar, M. S., Morgan, B., Dennerlein, S., Shah, A., El-Armouche, A., Nikolaev, V. O. & Katschinski, D. M., 14 Oct 2016, In : Circulation Research. 119, 9, p. 1004-1016 13 p.

    Research output: Contribution to journalArticle

  28. Apocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state

    Trevelin, S. C., Dos Santos, C. X., Ferreira, R. G., de Sá Lima, L., Silva, R. L., Scavone, C., Curi, R., Alves-Filho, J. C., Cunha, T. M., Roxo-Júnior, P., Cervi, M-C., Laurindo, F. R. M., Hothersall, J. S., Cobb, A. M., Zhang, M., Ivetic, A., Shah, A. M., Lopes, L. R. & Cunha, F. Q., 4 Oct 2016, In : Scientific Reports. 6, 34581.

    Research output: Contribution to journalArticle

  29. Does sex influence the diagnostic evaluation of autism spectrum disorder in adults?

    Wilson, C. E., Murphy, C. M., McAlonan, G., Robertson, D. M., Spain, D., Hayward, H., Woodhouse, E., Deeley, P. Q., Gillan, N., Ohlsen, J. C., Zinkstok, J., Stoencheva, V., Faulkner, J., Yildiran, H., Bell, V., Hammond, N., Craig, M. C. & Murphy, D. G. M., 1 Oct 2016, In : Autism. 20, 7, p. 808-819

    Research output: Contribution to journalArticle

  30. CRISPR/Cas9-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity

    Prior, K-K., Leisegang, M. S., Josipovic, I., Löwe, O., Shah, A. M., Weissmann, N., Schröder, K. & Brandes, R. P., Oct 2016, In : Redox Biology. 9, p. 287–295

    Research output: Contribution to journalArticle

  31. Glycoproteomics Reveals Decorin Peptides with Anti-Myostatin Activity in Human Atrial Fibrillation

    Barallobre-Barreiro, J., Gupta, S. K., Zoccarato, A., Kitazume-Taneike, R., Fava, M., Yin, X., Werner, T., Hirt, M. N., Zampetaki, A., Viviano, A., Chong, M., Bern, M., Kourliouros, A., Domenech, N., Willeit, P., Shah, A. M., Jahangiri, M., Schaefer, L., Fischer, J. W., Iozzo, R. V. & 6 others, Viner, R., Thum, T., Heineke, J., Kichler, A., Otsu, K. & Mayr, M., 13 Sep 2016, In : Circulation (Baltimore). 134, 11, p. 817-832 16 p.

    Research output: Contribution to journalArticle

  32. Magnetic Drug Targeting: Preclinical in Vivo Studies, Mathematical Modeling, and Extrapolation to Humans

    Al-Jamal, K. T., Bai, J., Tzu-Wen Wang, J., Protti, A., Southern, P., Bogart, L., Heidari, H., Li, X., Cakebread, A., Asker, D., Al-Jamal, W. T., Shah, A., Bals, S., Sosabowski, J. & Pankhurst, Q. A., 19 Aug 2016, In : Nano Letters. 16, 9, p. 5652-5660

    Research output: Contribution to journalLetter

  33. Molecular mechanisms linking autonomic dysfunction and impaired cardiac contractility in critical illness

    Ackland, G. L., Whittle, J., Toner, A., Machhada, A., Del Arroyo, A. G., Sciuso, A., Jenkins, N., Dyson, A., Struthers, R., Sneyd, J. R., Minto, G., Singer, M., Shah, A. & Gourine, A. V., 1 Aug 2016, In : Critical Care Medicine. 44, 8, p. e614-e624

    Research output: Contribution to journalArticle

  34. Potential Effect of Brexit on Cardiovascular Translational Science

    Shah, A. M. & Mann, D. L., 1 Aug 2016, In : JACC: Basic to Translational Science. 1, 5, p. 416-417 2 p.

    Research output: Contribution to journalArticle

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