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Research Outputs

  1. 2015
  2. Contractile Function during Angiotensin-II Activation: Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation

    Zhang, M., Prosser, B. L., Bamboye, M. A., Gondim, A. N. S., Santos, C. X., Martin, D., Ghigo, A., Perino, A., Brewer, A. C., Ward, C. W., Hirsch, E., Lederer, W. J. & Shah, A. M., 21 Jul 2015, In : Journal of the American College of Cardiology. 66, 3, p. 261-272 12 p.

    Research output: Contribution to journalArticle

  3. Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation

    Murakawa, T., Yamaguchi, O., Hashimoto, A., Hikoso, S., Takeda, T., Oka, T., Yasui, H., Ueda, H., Akazawa, Y., Nakayama, H., Taneike, M., Misaka, T., Omiya, S., Shah, A. M., Yamamoto, A., Nishida, K., Ohsumi, Y., Okamoto, K., Sakata, Y. & Otsu, K., 6 Jul 2015, In : Nature Communications. 6, p. 7527 1 p.

    Research output: Contribution to journalArticle

  4. Critical Appraisal on Orbital Decompression for Thyroid Eye Disease: A Systematic Review and Literature Search

    Boboridis, K. G., Uddin, J., Mikropoulos, D. G., Bunce, C., Mangouritsas, G., Voudouragkaki, I. C. & Konstas, A. G. P., Jul 2015, In : ADVANCES IN THERAPY. 32, 7, p. 595-611 17 p.

    Research output: Contribution to journalArticle

  5. Pegylated interferon-α-2b reduces corticosteroid requirement in patients with Behçet's disease with upregulation of circulating regulatory T cells and reduction of Th17.

    Lightman, S., Taylor, S. R. J., Bunce, C., Longhurst, H., Lynn, W., Moots, R., Stanford, M., Tomkins-Netzer, O., Yang, D., Calder, V. L. & Haskard, D. O., Jun 2015, Annals of the rheumatic diseases. BMJ Publishing Group Ltd and European League Against Rheumatism, p. 1138-44 7 p. (Annals of the rheumatic diseases; vol. 74).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  6. Ophthalmic statistics note 6: effect sizes matter

    Cook, J. A., Bunce, C., Doré, C. J., Freemantle, N. & Ophthalmic Statistics Group, May 2015, In : The British journal of ophthalmology. 99, 5, p. 580-1 2 p.

    Research output: Contribution to journalArticle

  7. Latanoprost for open-angle glaucoma (UKGTS): a randomised, multicentre, placebo-controlled trial

    Garway-Heath, D. F., Crabb, D. P., Bunce, C., Lascaratos, G., Amalfitano, F., Anand, N., Azuara-Blanco, A., Bourne, R. R., Broadway, D. C., Cunliffe, I. A., Diamond, J. P., Fraser, S. G., Ho, T. A., Martin, K. R., McNaught, A. I., Negi, A., Patel, K., Russell, R. A., Shah, A., Spry, P. G. & 5 others, Suzuki, K., White, E. T., Wormald, R. P., Xing, W. & Zeyen, T. G., 4 Apr 2015, In : The Lancet. 385, 9975, p. 1295-304 10 p.

    Research output: Contribution to journalArticle

  8. Quality of vision after bilateral multifocal intraocular lens implantation: A randomized trial - At LISA 809M versus AcrySof ReSTOR SN6AD1

    Maurino, V., Allan, B. D., Rubin, G. S., Bunce, C., Xing, W. & Findl, O., 1 Apr 2015, Ophthalmology. Elsevier Inc., p. 700-710 11 p. (Ophthalmology; vol. 122).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  9. Corneal collagen cross-linking for treating keratoconus

    Sykakis, E., Karim, R., Evans, J. R., Bunce, C., Amissah-Arthur, K. N., Patwary, S., McDonnell, P. J. & Hamada, S., 24 Mar 2015, In : Cochrane Database of Systematic Reviews. 3, CD010621.

    Research output: Contribution to journalArticle

  10. Cardiac-targeted NADPH oxidase 4 in the adaptive cardiac remodelling of the murine heart

    Nabeebaccus, A., Hafstad, A., Eykyn, T., Yin, X., Brewer, A., Zhang, M., Mayr, M. & Shah, A., 26 Feb 2015, In : Lancet. 385 Suppl 1, p. S73

    Research output: Contribution to journalArticle

  11. Certifications for sight impairment due to age related macular degeneration in England

    Bunce, C., Zekite, A., Walton, S., Rees, A. & Patel, P. J., Feb 2015, In : Public Health. 129, 2, p. 138-42 5 p.

    Research output: Contribution to journalArticle

  12. Heart failure: Mitochondrial dysfunction and oxidative stress in CHF

    Okonko, D. O. & Shah, A. M., 11 Jan 2015, In : Nature Reviews Cardiology. 12, 1, p. 6-8 3 p.

    Research output: Contribution to journalArticle

  13. Telemedicine for evaluation of retinopathy of prematurity.

    Fierson, W. M., Capone, A., American Academy of Pediatrics Section on Ophthalmology, AMERICAN. ACADEMY. OF. OPHTHALMOLOGY. A. AMERICAN. ASSOCIATION. OF. CERTIFIED. ORTHOPTISTS., American Academy of Ophthalmology, American Association of Certified Orthoptists, PG., Du, L., Gilbert, C., Foster, A., Collins, ML., Coats, DK., Good, WV., Menke, AM., Lee, P., Ells, AL., Holmes, JM., Astle, WF., Balasubramanian, M., Capone, A., Hartnett, ME., Pignatto, S., Trese, MT. & 76 others, Chiang, MF., Keenan, JD., Starren, J., Wu, C., Petersen, RA., VanderVeen, DK., Silva, RA., Murakami, Y., Jain, A., Gandhi, J., Lad, EM., Moshfeghi, DM., Quinn, GE., Ying, GS., Daniel, E., Conlin, PR., Fisch, BM., Orcutt, JC., Hetrick, BJ., Darkins, AW., Fransen, SR., Leonard-Martin, TC., Feuer, WJ., Hildebrand, PL., Zimmer-Galler, I., Zeimer, R., Wallace, DK., Quinn, GE., Freedman, SF., Chiang, MF., Kemper, AR., Wallace, DK., Quinn, GE., Field, M., Chiang, MF., Melia, M., Buffenn, AN., Schwartz, SD., Harrison, SA., Ferrone, PJ., Trese, MT., Lorenz, B., Spasovska, K., Elflein, H., Schneider, N., Silva, RA., Murakami, Y., Lad, EM., Moshfeghi, DM., Chiang, MF., Wang, L., Busuioc, M., Dhaliwal, C., Wright, E., Graham, C., McIntosh, N., Fleck, BW., Dai, S., Chow, K., Vincent, A., Koreen, S., Lopez, R., Jokl, DH., Flynn, JT., Chiang, MF., Mehta, M., Adams, GG., Bunce, C., Xing, W., Hill, M., Mukherjee, AN., Watts, P., Al-Madfai, H., Manoj, B., Roberts, D. & Fierson, WM., Jan 2015, Pediatrics. American Academy of Pediatrics, p. e238-54 (Pediatrics; vol. 135).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  14. Acute corneal hydrops in keratoconus: a national prospective study of incidence and management

    Barsam, A., Petrushkin, H., Brennan, N., Bunce, C., Xing, W., Foot, B. & Tuft, S., 2015, Eye (Lond). 2015/01/17 ed. (Eye (Lond)).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  15. Binocular versus standard occlusion or blurring treatment for unilateral amblyopia in children aged three to eight years

    Tailor, V., Bossi, M., Bunce, C., Greenwood, J. A. & Dahlmann-Noor, A., 2015, The Cochrane database of systematic reviews. p. CD011347 (The Cochrane database of systematic reviews; vol. 8).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  16. Ophthalmic statistics note 5: diagnostic tests—sensitivity and specificity.

    Saunders, L. J., Zhu, H., Bunce, C., Doré, C. J., Freemantle, N. & Crabb, D. P., 2015, The British journal of ophthalmology. p. 1168-70 3 p. (The British journal of ophthalmology; vol. 99).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  17. Parsing the role of NADPH oxidase enzymes and reactive oxygen species in heart failure

    Shah, A. M., 2015, In : Circulation (Baltimore). 131, 7, p. 602-604 3 p.

    Research output: Contribution to journalArticle

  18. Prescribed computer games in addition to occlusion versus standard occlusion treatment for childhood amblyopia: a pilot randomised controlled trial

    Tailor, V. K., Glaze, S., Khandelwal, P., Davis, A., Adams, G. G. W., Xing, W., Bunce, C. & Dahlmann-Noor, A., 2015, In : Pilot and Feasibility Studies. 1, p. 23

    Research output: Contribution to journalArticle

  19. Science forum: RIPOSTE: a framework for improving the design and analysis of laboratory-based research.

    Masca, N. G. D., Hensor, E. M. A., Cornelius, V. R., Buffa, F. M., Marriott, H. M., Eales, J. M., Messenger, M. P., Anderson, A. E., Boot, C., Bunce, C., Goldin, R. D., Harris, J., Hinchliffe, R. F., Junaid, H., Kingston, S., Martin-Ruiz, C., Nelson, C. P., Peacock, J., Seed, P. T., Shinkins, B. & 4 others, Staples, K. J., Toombs, J., Wright, A. K. A. & Teare, M. D., 2015, eLife. p. e05519 (eLife; vol. 4).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  20. 2014
  21. Menthol inhibits detrusor contractility independently of TRPM8 Activation

    Ramos-Filho, A. C. S., Shah, A., Augusto, T. M., Barbosa, G. O., Leiria, L. O., De Carvalho, H. F., Antunes, E. & Grant, A. D., 6 Nov 2014, In : PL o S One . 9, 11, e111616.

    Research output: Contribution to journalArticle

  22. NADPH oxidase 2 mediates angiotensin II-dependent cellular arrhythmias via PKA and CaMKII

    Wagner, S., Dantz, C., Flebbe, H., Azizian, A., Sag, C. M., Engels, S., Möllencamp, J., Dybkova, N., Islam, T., Shah, A. M. & Maier, L. S., 1 Oct 2014, In : Journal of Molecular and Cellular Cardiology. 75, p. 206-215 10 p.

    Research output: Contribution to journalArticle

  23. Description and evaluation of the first national patient and public involvement day for thyroid eye disease in the United Kingdom

    Smith, H. B., Porteous, C., Bunce, C., Bonstein, K., Hickey, J., Dayan, C. M., Adams, G., Rose, G. E. & Ezra, D. G., Sep 2014, In : Thyroid. 24, 9, p. 1400-6 7 p.

    Research output: Contribution to journalArticle

  24. Barriers to sight impairment certification in the UK: the example of a population with diabetes in East London

    Bourkiza, R., Subash, M., Qatarneh, D., Dacosta, J., Bunce, C. & Peto, T., 15 Aug 2014, In : Documenta Ophthalmologica. 14, p. 99

    Research output: Contribution to journalArticle

  25. Preface for redox signalling in the cardiovascular system

    Eaton, P. & Shah, A. M., Aug 2014, In : Journal of Molecular and Cellular Cardiology. 73, p. 1-1 1 p.

    Research output: Contribution to journalEditorial

  26. Redox regulation of cardiac hypertrophy

    Sag, C. M., Santos, C. X. C. & Shah, A. M., Aug 2014, In : Journal of Molecular and Cellular Cardiology. 73, p. 103-111 9 p.

    Research output: Contribution to journalLiterature review

  27. The imbalanced redox status in senescent endothelial cells is due to dysregulated Thioredoxin-1 and NADPH oxidase 4

    Goy, C., Czypiorski, P., Altschmied, J., Jakob, S., Rabanter, L. L., Brewer, A. C., Ale-Agha, N., Dyballa-Rukes, N., Shah, A. M. & Haendeler, J., Aug 2014, In : Experimental Gerontology. 56, p. 45-52 8 p.

    Research output: Contribution to journalArticle

  28. The Sight Loss and Vision Priority Setting Partnership (SLV-PSP): overview and results of the research prioritisation survey process

    Rowe, F., Wormald, R., Cable, R., Acton, M., Bonstein, K., Bowen, M., Bronze, C., Bunce, C., Conroy, D., Cowan, K., Evans, K., Fenton, M., Giles, H., Gordon, I., Halfhide, L., Harper, R., Lightstone, A., Votruba, M., Waterman, H. & Zekite, A., 23 Jul 2014, In : BMJ open. 4, 7, p. e004905

    Research output: Contribution to journalArticle

  29. How effective is eccentric viewing training? A systematic literature review

    Gaffney, A. J., Margrain, T. H., Bunce, C. V. & Binns, A. M., Jul 2014, In : Ophthalmic and Physiological Optics. 34, 4, p. 427-37 11 p.

    Research output: Contribution to journalArticle

  30. How many people in England and Wales are registered partially sighted or blind because of age-related macular degeneration?

    Rees, A., Zekite, A., Bunce, C. & Patel, P. J., Jul 2014, In : Eye (London, England). 28, 7, p. 832-7 6 p.

    Research output: Contribution to journalArticle

  31. Ophthalmic statistics note: the perils of dichotomising continuous variables

    Cumberland, P. M., Czanner, G., Bunce, C., Doré, C. J., Freemantle, N., García-Fiñana, M. & Ophthalmic Statistics Group, Jun 2014, In : The British journal of ophthalmology. 98, 6, p. 841-3 3 p.

    Research output: Contribution to journalArticle

  32. Erratum: The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response (Cell (2014) 157 (741-743))

    Puente, B. N., Kimura, W., Muralidhar, S. A., Moon, J., Amatruda, J. F., Phelps, K. L., Grinsfelder, D., Rothermel, B. A., Chen, R., Garcia, J. A., Santos, C. X., Thet, S., Mori, E., Kinter, M. T., Rindler, P. M., Zacchigna, S., Mukherjee, S., Chen, D. J., Mahmoud, A. I., Giacca, M. & 5 others, Rabinovitch, P. S., Asaithamby, A., Shah, A. M., Szweda, L. I. & Sadek, H. A., 22 May 2014, In : Cell. 157, 5, 1 p.

    Research output: Contribution to journalComment/debate

  33. ROS signalling between endothelial cells and cardiac cells

    Zhang, M. & Shah, A. M., 1 May 2014, In : Cardiovascular Research. 102, 2, p. 249-257 9 p.

    Research output: Contribution to journalLiterature review

  34. A randomized trial to assess functional and structural effects of ranibizumab versus laser in diabetic macular edema (the LUCIDATE study)

    Comyn, O., Sivaprasad, S., Peto, T., Neveu, M. M., Holder, G. E., Xing, W., Bunce, C. V., Patel, P. J., Egan, C. A., Bainbridge, J. W. & Hykin, P. G., May 2014, In : American Journal of Ophthalmology. 157, 5, p. 960-70 11 p.

    Research output: Contribution to journalArticle

  35. An Ongoing Role of alpha-Calcitonin Gene-Related Peptide as Part of a Protective Network Against Hypertension, Vascular Hypertrophy, and Oxidative Stress

    Smillie, S-J., King, R., Kodji, X., Outzen, E., Pozsgai, G., Fernandes, E., Marshall, N., de Winter, P., Heads, R. J., Dessapt-Baradez, C., Gnudi, L., Sams, A., Shah, A. M., Siow, R. C. & Brain, S. D., May 2014, In : Hypertension. 63, 5, p. 1056-1062 7 p.

    Research output: Contribution to journalArticle

  36. EURObservational Research Programme: a worldwide registry on peripartum cardiomyopathy (PPCM) in conjunction with the Heart Failure Association of the European Society of Cardiology Working Group on PPCM

    Sliwa, K., Hilfiker-Kleiner, D., Mebazaa, A., Petrie, M. C., Maggioni, A. P., Regitz-Zagrosek, V., Schaufelberger, M., Tavazzi, L., van Veldhuisen, D. J., Roos-Hesslink, J. W., Shah, A. J., Seferovic, P. M., Elkayam, U., van Spaendonck-Zwarts, K., Bachelier-Walenta, K., Mouquet, F., Kraigher-Krainer, E., Hall, R., Ponikowski, P., McMurray, J. J. V. & 1 others, Pieske, B., May 2014, In : EUROPEAN JOURNAL OF HEART FAILURE. 16, 5, p. 583-591 9 p.

    Research output: Contribution to journalArticle

  37. Ophthalmic statistics note 2: absence of evidence is not evidence of absence

    Bunce, C., Patel, K. V., Xing, W., Freemantle, N., Doré, C. J. & Ophthalmic Statistics Group, May 2014, In : The British journal of ophthalmology. 98, 5, p. 703-5 3 p.

    Research output: Contribution to journalArticle

  38. The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage Response

    Puente, B. N., Kimura, W., Muralidhar, S. A., Moon, J., Amatruda, J. F., Phelps, K. L., Grinsfelder, D., Rothermel, B. A., Chen, R., Garcia, J. A., Santos, C. X., Thet, S., Mori, E., Kinter, M. T., Rindler, P. M., Zacchigna, S., Mukherjee, S., Chen, D. J., Mahmoud, A. I., Giacca, M. & 5 others, Rabinovitch, P. S., Aroumougame, A., Shah, A. M., Szweda, L. I. & Sadek, H. A., 24 Apr 2014, In : Cell. 157, 3, p. 565-579 15 p.

    Research output: Contribution to journalArticle

  39. Magnetically Decorated Multiwalled Carbon Nanotubes as Dual MRI and SPECT Contrast Agents

    Wang, J. T., Cabana, L., Bourgognon, M., Kafa, H., Protti, A., Venner, K., Shah, A. M., Sosabowski, J. K., Mather, S. J., Roig, A., Ke, X., Van Tendeloo, G., De Rosales, R. T. M., Tobias, G. & Al-jamal, K. T., 2 Apr 2014, In : Advanced Functional Materials. 24, 13, p. 1880-1894 15 p.

    Research output: Contribution to journalArticle

  40. Response to Swampillai et al

    Saleh, G. M., Theodoraki, K., Gillan, S., Sullivan, P., O'Sullivan, F., Hussain, B., Bunce, C. & Athanasiadis, I., Apr 2014, In : Eye (London, England). 28, 4, p. 503-4 2 p.

    Research output: Contribution to journalArticle

  41. The evaluation and surgical management of cyclodialysis clefts that have failed to respond to conservative management

    Ioannidis, A. S., Bunce, C. & Barton, K., Apr 2014, In : The British journal of ophthalmology. 98, 4, p. 544-9 6 p.

    Research output: Contribution to journalArticle

  42. Peroxidasin-like protein: a novel peroxidase homologue in the human heart

    Peterfi, Z., Toth, Z. E., Kovacs, H. A., Lazar, E., Sum, A., Donko, A., Sirokmany, G., Shah, A. M. & Geiszt, M., 1 Mar 2014, In : Cardiovascular Research. 101, 3, p. 393-399 7 p., N/A.

    Research output: Contribution to journalArticle

  43. Ophthalmic statistics note 1: unit of analysis

    Bunce, C., Patel, K. V., Xing, W., Freemantle, N., Doré, C. J. & Ophthalmic Statistics Group, Mar 2014, In : The British journal of ophthalmology. 98, 3, p. 408-12 5 p.

    Research output: Contribution to journalArticle

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