King's College London

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Research Outputs

  1. 2012
  2. Prospective Study on Circulating MicroRNAs and Risk of Myocardial Infarction

    Zampetaki, A., Willeit, P., Tilling, L., Drozdov, I., Prokopi, M., Renard, J-M., Mayr, A., Weger, S., Schett, G., Shah, A., Boulanger, C. M., Willeit, J., Chowienczyk, P. J., Kiechl, S. & Mayr, M., 24 Jul 2012, In : Journal of the American College of Cardiology. 60, 4, p. 290-299 10 p.

    Research output: Contribution to journalArticle

  3. Myocardial Wall Stress From Hypertension to Heart Tension

    Chowienczyk, P. & Shah, A., Jul 2012, In : Hypertension. 60, 1, p. 10-11 2 p.

    Research output: Contribution to journalEditorial

  4. Response to the Letter by Schmidt et al Regarding "Nox4 Is a Janus-Faced Reactive Oxygen Species Generating NADPH Oxidase"

    Schroeder, K., Benkhoff, S., Mieth, A., Pliquett, R., Kosowski, J., Kruse, C., Michaelis, U. R., Dimmeler, S., Brandes, R. P., Zhang, M., Shah, A. M., Luedike, P. & Weissmann, N., 22 Jun 2012, In : Circulation Research. 111, 1, p. E17-E18 2 p.

    Research output: Contribution to journalLetter

  5. Role of neuronal vs endothelial nitric oxide synthase in the coronary blood flow response to pacing

    Shabeeh, H., Melikian, N., Dworakowski, R., Casadei, B., Chowienczyk, P. & Shah, A. M., May 2012, In : Heart. 98, S1, p. A60-A61 2 p.

    Research output: Contribution to journalMeeting abstract

  6. Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase

    Schroeder, K., Zhang, M., Benkhoff, S., Mieth, A., Pliquett, R., Kosowski, J., Kruse, C., Luedike, P., Michaelis, U. R., Weissmann, N., Dimmeler, S., Shah, A. M. & Brandes, R. P., 27 Apr 2012, In : Circulation Research. 110, 9, p. 1217-1225 8 p.

    Research output: Contribution to journalArticle

  7. Increasing Circulating IGFBP1 Levels Improves Insulin Sensitivity, Promotes Nitric Oxide Production, Lowers Blood Pressure, and Protects Against Atherosclerosis

    Rajwani, A., Ezzat, V., Smith, J., Yuldasheva, N. Y., Duncan, E. R., Gage, M., Cubbon, R. M., Kahn, M. B., Imrie, H., Abbas, A., Viswambharan, H., Aziz, A., Sukumar, P., Vidal-Puig, A., Sethi, J. K., Xuan, S., Shah, A. M., Grant, P. J., Porter, K. E., Kearney, M. T. & 1 others, Wheatcroft, S. B., Apr 2012, In : Diabetes. 61, 4, p. 915 - 924 10 p.

    Research output: Contribution to journalArticle

  8. Proteomics Analysis of Cardiac Extracellular Matrix Remodeling in a Porcine Model of Ischemia/Reperfusion Injury

    Barallobre-Barreiro, J., Didangelos, A., Schoendube, F. A., Drozdov, I., Yin, X., Fernandez-Caggiano, M., Willeit, P., Puntmann, V. O., Aldama-Lopez, G., Shah, A. M., Domenech, N. & Mayr, M., 14 Feb 2012, In : Circulation (Baltimore). 125, 6, p. 789 - 802 14 p.

    Research output: Contribution to journalArticle

  9. Leptin promotes the mobilization of vascular progenitor cells and neovascularization by NOX2-mediated activation of MMP9

    Schroeter, M. R., Stein, S., Heida, N-M., Leifheit-Nestler, M., Cheng, I-F., Gogiraju, R., Christiansen, H., Maier, L. S., Shah, A. M., Hasenfuss, G., Konstantinides, S. & Schaefer, K., 1 Jan 2012, In : Cardiovascular Research. 93, 1, p. 170 - 180 11 p.

    Research output: Contribution to journalArticle

  10. Activation of TRPC6 channels is essential for lung ischaemia-reperfusion induced oedema in mice

    Weissmann, N., Sydykov, A., Kalwa, H., Storch, U., Fuchs, B., Mederos y Schnitzler, M., Brandes, R. P., Grimminger, F., Meissner, M., Freichel, M., Offermanns, S., Veit, F., Pak, O., Krause, K-H., Schermuly, R. T., Brewer, A. C., Schmidt, H. H. H. W., Seeger, W., Shah, A. M., Gudermann, T. & 2 others, Ghofrani, H. A. & Dietrich, A., 2012, In : Nature Communications. 3, 649.

    Research output: Contribution to journalArticle

  11. NADPH Oxidase 4 essentially contributes to nociceptive processing in neuropathic pain states

    Kallenborn-Gerhardt, W., Schroeder, K., Del Turco, D., Lu, R., Kynast, K., Kosowski, J., Niederberger, E., Shah, A. M., Brandes, R. P., Geisslinger, G. & Schmidtko, A., 2012, In : Naunyn-Schmiedeberg's Archives of Pharmacology. 385, p. 43 - 43 1 p.

    Research output: Contribution to journalMeeting abstract

  12. Six-year survival of a patient with pulmonary artery angiosarcoma

    Chaubey, S., Benson, C., Khan, H., Monaghan, M., Shah, A. M., Judson, I. & Wendler, O., 2012, In : Asian Cardiovascular & Thoracic Annals. 20, 6, p. 728-730 3 p.

    Research output: Contribution to journalArticle

  13. 2011
  14. NADPH oxidases in cardiovascular disease: insights from in vivo models and clinical studies

    Sirker, A., Zhang, M. & Shah, A. M., Sep 2011, In : Basic Research in Cardiology. 106, 5, p. 735 - 747 13 p.

    Research output: Contribution to journalLiterature review

  15. Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo

    Brewer, AC., Murray, T., Arno, M., Zhang, M., Anilkumar, N., Mann, G. & Shah, AM., 1 Jul 2011, In : Free Radical Biology and Medicine. 51, 1, p. 205 - 215 11 p.

    Research output: Contribution to journalArticle

  16. Changing Characteristics and Mode of Death Associated With Chronic Heart Failure Caused by Left Ventricular Systolic Dysfunction A Study Across Therapeutic Eras

    Cubbon, R. M., Gale, C. P., Kearney, L. C., Schechter, C. B., Brooksby, W. P., Nolan, J., Fox, K. A. A., Rajwani, A., Baig, W., Groves, D., Barlow, P., Fisher, A. C., Batin, P. D., Kahn, M. B., Zaman, A. G., Shah, A. M., Byrne, J. A., Lindsay, S. J., Sapsford, R. J., Wheatcroft, S. B. & 2 others, Witte, K. K. & Kearney, M. T., Jul 2011, In : Circulation-Heart Failure. 4, 4, p. 396-403 8 p.

    Research output: Contribution to journalArticle

  17. Remote intermittent ischemia before coronary artery bypass graft surgery: a strategy to reduce injury and inflammation?

    Karuppasamy, P., Chaubey, S., Dew, T., Musto, R., Sherwood, R., Desai, J., John, L., Shah, A. M., Marber, M. S. & Kunst, G., Jul 2011, In : Basic Research in Cardiology. 106, 4, p. 511 - 519 9 p.

    Research output: Contribution to journalArticle

  18. The E-loop Is Involved in Hydrogen Peroxide Formation by the NADPH Oxidase Nox4

    Takac, I., Schroeder, K., Zhang, L., Lardy, B., Anilkumar, N., Lambeth, J. D., Shah, A. M., Morel, F. & Brandes, R. P., 15 Apr 2011, In : Journal of Biological Chemistry. 286, 15, p. 13304 - 13313 10 p.

    Research output: Contribution to journalArticle

  19. Redox signaling in cardiac myocytes

    Xavier Da Costa Dos Santos, C. S., Anilkumar, N., Zhang, M., Brewer, A. C. & Shah, A. M., 1 Apr 2011, In : Free Radical Biology and Medicine. 50, 7, p. 777 - 793 17 p.

    Research output: Contribution to journalLiterature review

  20. Control of Hepatic Nuclear Superoxide Production by Glucose 6-Phosphate Dehydrogenase and NADPH Oxidase-4

    Spencer, N. Y., Yan, Z., Boudreau, R. L., Zhang, Y., Luo, M., Li, Q., Tian, X., Shah, A. M., Davisson, R. L., Davidson, B., Banfi, B. & Engelhardt, J. F., 18 Mar 2011, In : Journal of Biological Chemistry. 286, 11, p. 8977 - 8987 11 p.

    Research output: Contribution to journalArticle

  21. Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology

    Eschenhagen, T., Force, T., Ewer, M. S., de Keulenaer, G. W., Suter, T. M., Anker, S. D., Avkiran, M., de Azambuja, E., Balligand, J-L., Brutsaert, D. L., Condorelli, G., Hansen, A., Heymans, S., Hill, J. A., Hirsch, E., Hilfiker-Kleiner, D., Janssens, S., de Jong, S., Neubauer, G., Pieske, B. & 8 others, Ponikowski, P., Pirmohamed, M., Rauchhaus, M., Sawyer, D., Sugden, P. H., Wojta, J., Zannad, F. & Shah, A. M., Jan 2011, In : EUROPEAN JOURNAL OF HEART FAILURE. 13, 1, p. 1 - 10 10 p.

    Research output: Contribution to journalArticle

  22. NADPH oxidases and cardiac remodelling

    Nabeebaccus, A., Zhang, M. & Shah, A. M., Jan 2011, In : Heart Failure Reviews. 16, 1, p. 5 - 12 8 p.

    Research output: Contribution to journalArticle

  23. Altered PDE5 Targeting in Pathologic Hearts. Switching From NO-cGMP to ANP/BNP-cGMP

    Zhang, M., Takimoto, E., Lee, D. I., Xavier Da Costa Dos Santos, C. S., Hsu, S., Bedja, D., Yuan, Y., Eaton, P., Shah, A. & Kass, D., 2011, In : Circulation (Baltimore). 124, 21

    Research output: Contribution to journalMeeting abstract

  24. CELL-SPECIFIC ROLE OF NOX2 NADPH OXIDASE IN DEVELOPMENT OF ANGIOTENSIN II-INDUCED CARDIAC FIBROSIS IN VIVO

    Chaubey, S., Murdoch, C. E., Ivetic, A., Yu, B., Vanhoutte, D., Heymans, S., Brewer, A. & Shah, A. M., 2011, In : Heart. 97, p. A77 - A78

    Research output: Contribution to journalMeeting abstract

  25. Heart Failure 1 In search of new therapeutic targets and strategies for heart failure: recent advances in basic science

    Shah, A. M. & Mann, D. L., 2011, In : The Lancet. 378, 9792, p. 704 - 712 9 p.

    Research output: Contribution to journalArticle

  26. 2010
  27. Nox2 NADPH Oxidase Promotes Pathologic Cardiac Remodeling Associated with Doxorubicin Chemotherapy

    Zhao, Y., McLaughlin, D., Robinson, E., Harvey, A. P., Hookham, M. B., Shah, A. M., McDermott, B. J. & Grieve, D. J., 15 Nov 2010, In : Cancer Research. 70, 22, p. 9287 - 9297 11 p.

    Research output: Contribution to journalArticle

  28. Genome-wide expression patterns in physiological cardiac hypertrophy

    Drozdov, I., Tsoka, S., Ouzounis, C. A. & Shah, A. M., 11 Oct 2010, In : BMC GENOMICS. 11, 1, 557.

    Research output: Contribution to journalArticle

  29. Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes

    Zampetaki, A., Kiechl, S., Drozdov, I., Willeit, P., Mayr, U., Prokopi, M., Mayr, A., Weger, S., Oberhollenzer, F., Bonora, E., Shah, A., Willeit, J. & Mayr, M., 17 Sep 2010, In : Circulation Research. 107, 6, p. 810 - 817 8 p.

    Research output: Contribution to journalArticle

  30. Oxidative Stress and Endothelial Dysfunction in Aortas of Aged Spontaneously Hypertensive Rats by NOX1/2 Is Reversed by NADPH Oxidase Inhibition

    Wind, S., Beuerlein, K., Armitage, M. E., Taye, A., Kumar, A. H. S., Janowitz, D., Neff, C., Shah, A. M., Wingler, K. & Schmidt, H. H. H. W., Sep 2010, In : Hypertension. 56, 3, p. 490 - U319 8 p.

    Research output: Contribution to journalArticle

  31. Post-Stroke Inhibition of Induced NADPH Oxidase Type 4 Prevents Oxidative Stress and Neurodegeneration

    Kleinschnitz, C., Grund, H., Wingler, K., Armitage, M. E., Jones, E., Mittal, M., Barit, D., Schwarz, T., Geis, C., Kraft, P., Barthel, K., Schuhmann, M. K., Herrmann, A. M., Meuth, S. G., Stoll, G., Meurer, S., Schrewe, A., Becker, L., Gailus-Durner, V., Fuchs, H. & 6 others, Klopstock, T., de Angelis, M. H., Jandeleit-Dahm, K., Shah, A. M., Weissmann, N. & Schmidt, H. H. H. W., Sep 2010, In : PL o S Biology. 8, 9, e1000479.

    Research output: Contribution to journalArticle

  32. Role of Phosphoinositide 3-Kinase alpha, Protein Kinase C, and L- Type Ca2+ Channels in Mediating the Complex Actions of Angiotensin II on Mouse Cardiac Contractility

    Liang, W., Oudit, G. Y., Patel, M. M., Shah, A. M., Woodgett, J. R., Tsushima, R. G., Ward, M. E. & Backx, P. H., Sep 2010, In : Hypertension. 56, 3, p. 422 - 429 8 p.

    Research output: Contribution to journalArticle

  33. Current state of knowledge on aetiology, diagnosis, management, and therapy of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society of Cardiology Working Group on peripartum cardiomyopathy

    Sliwa, K., Hilfiker-Kleiner, D., Petrie, M. C., Mebazaa, A., Pieske, B., Buchmann, E., Regitz-Zagrosek, V., Schaufelberger, M., Tavazzi, L., van Veldhuisen, D. J., Watkins, H., Shah, A. J., Seferovic, P. M., Elkayam, U., Pankuweit, S., Papp, Z., Mouquet, F. & McMurray, J. J. V., Aug 2010, In : EUROPEAN JOURNAL OF HEART FAILURE. 12, 8, p. 767 - 778 12 p.

    Research output: Contribution to journalArticle

  34. Biochemistry and physiology of cardiac muscle

    Sirker, A. & Shah, AM., Jul 2010, In : Medicine. 38, 7, p. 340-343 4 p.

    Research output: Contribution to journalArticle

  35. Meeting highlights from the 2010 European Society of Cardiology Heart Failure Association Winter Meeting: Translational Heart Failure Research

    de Boer, R. A., Shah, A. M. & Sillje, H. H. W., May 2010, In : EUROPEAN JOURNAL OF HEART FAILURE. 12, 5, p. 417 - 419 3 p.

    Research output: Contribution to journalEditorial

  36. Involvement of NADPH oxidase in age-associated cardiac remodeling

    Wang, M., Zhang, J., Walker, S. J., Dworakowski, R., Lakatta, E. G. & Shah, A. M., Apr 2010, In : Journal of Molecular and Cellular Cardiology. 48, 4, p. 765 - 772 8 p.

    Research output: Contribution to journalArticle

  37. ENDOTHELIAL-SPECIFIC OVEREXPRESSION OF NOX2 ENHANCES ANGIOTENSIN II-INDUCED CARDIAC DYSFUNCTION AND FIBROSIS

    Murdoch, C. E., Brewer, A., Zhang, M., Vanhoutte, D., Heymans, S. & Shah, A. M., 2010, In : Heart. 96, 4

    Research output: Contribution to journalMeeting abstract

  38. Functional Characterisation of Nox4D Splice Variant of Nox4 NADPH Oxidase Expressed in Vascular Smooth Muscle Cells

    Anilkumari, N. P., Brewer, A. C., Sawyer, I., Eneriz, G. S. J. & Shah, A., 2010, In : Free Radical Biology and Medicine. 49, p. S91-S91

    Research output: Contribution to journalMeeting abstract

  39. NOX ENZYMES AND THE DEVELOPMENT OF HEART FAILURE

    Shah, A., 2010, In : Free Radical Biology and Medicine. 49, p. S4-S4

    Research output: Contribution to journalMeeting abstract

  40. Oxidative Stress and redox signalling in cardiac remodelling

    Zhang, M., Sirker, A. & Shah, A., 2010, Oxidative Stress in Applied Basic Research and Clinical Practice: Studies on Cardiovascular Disorders. Sauer, H., Shah, AM. & Laurindo, FRM. (eds.). Springer Humana, p. 405 - 424 20 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  41. Regulation of the Nrf2 Antioxidant Pathway by NOX4 in the Postnatal Heart

    Brewer, A., Murray, T. & Shah, A., 2010, In : Free Radical Biology and Medicine. 49, p. S126-S126

    Research output: Contribution to journalMeeting abstract

  42. Spotlight: Ajay Shah, MD, FRCP, FESC, FMedSci

    Ozkan, J. & Shah, A., 2010, In : Circulation (Baltimore). 122, 5, p. F25 - F27 3 p.

    Research output: Contribution to journalEditorial

  43. The H2O2-producing NADPH Oxidase Nox4 Protects Against Angiotensin II Induced Vascular Hypertrophy and Inflammation

    Schroeder, K., Mieth, A., Benkhoff, S., Zhang, M., Shah, A. M. & Brandes, R. P., 2010, In : Free Radical Biology and Medicine. 49, p. S29-S29

    Research output: Contribution to journalMeeting abstract

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