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Research Outputs

  1. 2009
  2. Protection of Angiotensin II-Induced Vascular Hypertrophy in Vascular Smooth Muscle-Targeted Receptor Activity-Modifying Protein 2 Transgenic Mice

    Liang, L., Tam, C., Pozsgai, G., Siow, R., Clark, N., Keeble, J., Husmann, K., Born, W., Fischer, J. A., Poston, R., Shah, A. & Brain, S. D., Dec 2009, In : Hypertension. 54, 6, p. 1254 - 1261 8 p.

    Research output: Contribution to journalArticle

  3. Neuronal Nitric Oxide Synthase and Human Vascular Regulation

    Melikian, N., Seddon, M. D., Casadei, B., Chowienczyk, P. J. & Shah, A. M., Nov 2009, In : TRENDS IN CARDIOVASCULAR MEDICINE. 19, 8, p. 256 - 262 7 p.

    Research output: Contribution to journalLiterature review

  4. NADPH oxidase signaling and cardiac myocyte function

    Akki, A., Zhang, M., Murdoch, C., Brewer, A. & Shah, A. M., Jul 2009, In : Journal of Molecular and Cellular Cardiology. 47, 1, p. 15 - 22 8 p.

    Research output: Contribution to journalLiterature review

  5. Redox signalling and miRNA function in cardiomyocytes

    Brewer, A. C. & Shah, A. M., Jul 2009, In : Journal of Molecular and Cellular Cardiology. 47, 1, p. 2 - 4 3 p.

    Research output: Contribution to journalEditorial

  6. Redox sensitive signaling pathways in cardiac remodeling, hypertrophy and failure

    Anilkumar, N., Sirker, A. & Shah, A. M., 1 Jun 2009, In : Frontiers in Bioscience. 14, 6, p. 3168 - 3187 20 p.

    Research output: Contribution to journalLiterature review

  7. Defective peroxisomal proliferators activated receptor gamma activity due to dominant‐negative mutation synergizes with hypertension to accelerate cardiac fibrosis in mice

    Kis, A., Murdoch, C., Zhang, M., Siva, A., Rodriguez-Cuenca, S., Carobbio, S., Lukasik, A., Blount, M., O'Rahilly, S., Gray, S. L., Shah, A. M. & Vidal-Puig, A., Jun 2009, In : EUROPEAN JOURNAL OF HEART FAILURE. 11, 6, p. 533 - 541 9 p.

    Research output: Contribution to journalArticle

  8. Effects of Neuronal Nitric Oxide Synthase on Human Coronary Artery Diameter and Blood Flow In Vivo

    Seddon, M., Melikian, N., Dworakowski, R., Shabeeh, H., Jiang, B., Byrne, J., Casadei, B., Chowienczyk, P. & Shah, A. M., 26 May 2009, In : Circulation (Baltimore). 119, 20, p. 2656 - 2662 7 p.

    Research output: Contribution to journalArticle

  9. Protein phosphatase 2A contributes to the cardiac dysfunction induced by endotoxemia

    Marshall, M., Anilkumar, N., Layland, J., Walker, S. J., Kentish, J. C., Shah, A. M. & Cave, A. C., Apr 2009, In : Cardiovascular Research. 82, 1, p. 67 - 76 10 p.

    Research output: Contribution to journalArticle

  10. Inflammation as a therapeutic target in heart failure? A scientific statement from the Translational Research Committee of the Heart Failure Association of the European Society of Cardiology.

    Heymans, S., Hirsch, E., Anker, SD., Aukrust, P., Balligand, JL., Cohen-Tervaert, JW., Drexler, H., Fillippatos, G., Felix, SB., Gullestad, L., Hilfiker-Kleiner, D., Janssens, S., Latini, R., Neubauer, G., Paulus, WJ., Pieske, B., Ponikowski, P., Schroen, B., Schultheiss, HP., Tschope, C. & 4 others, Van Bilsen, M., Zannad, F., McMurray, J. & Shah, AM., Feb 2009, In : EUROPEAN JOURNAL OF HEART FAILURE. 11, 2, p. 119 - 129 11 p.

    Research output: Contribution to journalArticle

  11. 2008
  12. Effect of Endothelium-Specific Insulin Resistance on Endothelial Function In Vivo

    Duncan, E. R., Crossey, P. A., Walker, S., Anilkumar, N., Poston, L., Douglas, G., Ezzat, V. A., Wheatcroft, S. B., Shah, A. M. & Kearney, M. I., Dec 2008, In : Diabetes. 57, 12, p. 3307 - 3314 8 p.

    Research output: Contribution to journalArticle

  13. Positive regulation of the NADPH oxidase NOX4 promoter in vascular smooth muscle cells by E2F

    Zhang, L., Sheppard, O. R., Shah, A. M. & Brewer, A. C., 1 Sep 2008, In : Free Radical Biology and Medicine. 45, 5, p. 679 - 685 7 p.

    Research output: Contribution to journalArticle

  14. Homocysteine, migration and early vascular impairment in people of African descent

    Kalra, L., Iveson, E., Rambaran, C., Sherwood, R., Chowienczyk, P., Ritter, J., Shah, A. & Forrester, T., Sep 2008, In : Heart. 94, 9, p. 1171 - 1174 4 p.

    Research output: Contribution to journalArticle

  15. Glycogen synthase kinase-3 inactivation is not required for ischemic preconditioning or postconditioning in the mouse

    Nishino, Y., Webb, I. G., Davidson, S. M., Ahmed, A. I., Clark, J. E., Jacquet, S., Shah, A. M., Miura, T., Yellon, D. M., Avkiran, M. & Marber, M. S., 1 Aug 2008, In : Circulation Research. 103, 3, p. 307 - 314 8 p.

    Research output: Contribution to journalArticle

  16. Nox4 and Nox2 NADPH oxidases mediate distinct cellular redox signaling responses to agonist stimulation

    Anilkumar, N., Weber, R., Zhang, M., Brewer, A. & Shah, A. M., 1 Jul 2008, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 28, 7, p. 1347 - 1354 8 p.

    Research output: Contribution to journalArticle

  17. An international matched cohort study of the contribution of metabolic impairments to subclinical atherosclerosis in United Kingdom and Jamaican African-Caribbeans

    Kalra, L., Iveson, E., Rambaran, C., Sherwood, R., Chowienczyk, P., Ritter, J., Shah, A. & Forrester, T., Jul 2008, In : Atherosclerosis. 199, 1, p. 95 - 101 7 p.

    Research output: Contribution to journalArticle

  18. Cardiomyocyte overexpression of neuronal nitric oxide synthase delays transition toward heart failure in response to pressure overload by preserving calcium cycling

    Loyer, X., Gomez, A. M., Milliez, P., Fernandez-Velasco, M., Vangheluwe, P., Vinet, L., Charue, D., Vaudin, E., Zhang, W., Sainte-Marie, Y., Robidel, E., Marty, I., Mayer, B., Jaisser, F., Mercadier, J. J., Richard, S., Shah, A. M., Benitah, J. P., Samuel, J. L. & Heymes, C., 24 Jun 2008, In : Circulation (Baltimore). 117, 25, p. 3187 - 3198 12 p.

    Research output: Contribution to journalArticle

  19. Ethnic differences in left ventricular remodeling in highly-trained athletes - Relevance to differentiating physiologic left ventricular hypertrophy from hypertrophic cardiomyopathy

    Basavarajaiah, S., Boraita, A., Whyte, G., Wilson, M., Carby, L., Shah, A. & Sharma, S., 10 Jun 2008, In : Journal of the American College of Cardiology. 51, 23, p. 2256 - 2262 7 p.

    Research output: Contribution to journalArticle

  20. Reactive oxygen species and endothelial activation

    om-Ruiz, S. P., Anilkumar, N. & Shah, A. M., 1 Jun 2008, In : ANTIOXIDANTS AND REDOX SIGNALING. 10, 6, p. 1089 - 1100 12 p.

    Research output: Contribution to journalLiterature review

  21. Low-volume hydrodynamic gene delivery to the rat liver via an isolated segment of the inferior vena cava: efficiency, cardiovascular response and intrahepatic vascular dynamics

    Sawyer, G. J., Grehan, A., Dong, X. B., Whitehorne, M., Seddon, M., Shah, A. M., Zhang, X. H., Salehi, S. & Fabre, J. W., May 2008, In : JOURNAL OF GENE MEDICINE. 10, 5, p. 540 - 550 11 p.

    Research output: Contribution to journalArticle

  22. Reduced nicotinamide adenine dinucleotide phosphate oxidase-derived superoxide and vascular endothelial dysfunction in human heart failure

    Dworakowski, R., Walker, S., Momin, A., Desai, J., El-Gamel, A., Wendler, O., Kearney, M. T. & Shah, A. M., 8 Apr 2008, In : Journal of the American College of Cardiology. 51, 14, p. 1349 - 1356 8 p.

    Research output: Contribution to journalArticle

  23. A reactive oxygen species-mediated component in neurogenic vasodilatation

    Starr, A., Graepel, R., Keeble, J., Schmidhuber, S., Clark, N., Grant, A., Shah, A. M. & Brain, S. D., Apr 2008, In : Cardiovascular Research. 78, 1, p. 139 - 147 9 p.

    Research output: Contribution to journalArticle

  24. Neuronal nitric oxide synthase regulates basal microvascular tone in humans in vivo

    Seddon, M. D., Chowienczyk, P. J., Brett, S. E., Casadei, B. & Shah, A. M., Apr 2008, In : Circulation (Baltimore). 117, 15, p. 1991 - 1996 6 p.

    Research output: Contribution to journalArticle

  25. Prevalence of hypertrophic cardiomyopathy in highly trained athletes: Relevance to pre-participation screening

    Basavarajaiah, S., Wilson, M., Whyte, G., Shah, A., McKenna, W. & Sharma, S., 11 Mar 2008, In : Journal of the American College of Cardiology. 51, 10, p. 1033 - 1039 7 p.

    Research output: Contribution to journalArticle

  26. Determinants of endothelial function in asymptomatic subjects with and without the metabolic syndrome

    Melikian, N., Chowienczyk, P., MacCarthy, P. A., Williams, I. L., Wheatcroft, S. B., Sherwood, R., Gale, C., Shah, A. M. & Kearney, M. T., Mar 2008, In : Atherosclerosis. 197, 1, p. 375 - 382 8 p.

    Research output: Contribution to journalArticle

  27. Hydrodynamic gene delivery to the pig liver via an isolated segment of the inferior vena cava

    Fabre, J. W., Grehan, A., Whitehorne, M., Sawyer, G. J., Dong, X., Salehi, S., Eckley, L., Zhang, X., Seddon, M., Shah, A. M., Davenport, M. & Rela, M., Mar 2008, In : Gene Therapy. 15, 6, p. 452 - 462 11 p.

    Research output: Contribution to journalArticle

  28. A role for GATA-6 in vertebrate chondrogenesis

    Alexandrovich, A., Qureishi, A., Coudert, A., Zhang, L., Grigoriadis, A., Shah, A. M., Brewer, A. C. & Pizzey, J. A., 15 Feb 2008, In : Developmental Biology. 314, 2, p. 457 - 470 14 p.

    Research output: Contribution to journalArticle

  29. Involvement of Nox2 NADPH oxidase in adverse cardiac remodeling after myocardial infarction

    Looi, Y. H., Grieve, D. J., Siva, A., Walker, S. J., Anilkumar, N., Cave, A. C., Marber, M., Monaghan, M. J. & Shah, A. M., Feb 2008, In : Hypertension. 51, 2, p. 319 - 325 7 p.

    Research output: Contribution to journalArticle

  30. NADPH oxidase-derived reactive oxygen species in the regulation of endothelial phenotype

    Dworakowski, R., om-Ruiz, S. P. & Shah, A. M., 2008, In : Pharmacological Reports. 60, 1, p. 21 - 28 8 p.

    Research output: Contribution to journalLiterature review

  31. NADPH oxidase-derived superoxide and vascular endothelial dysfunction in human heart failure

    Dworakowski, R., Walker, S., Momin, A., Desai, J., El-Gamel, A., Wendler, O., Kearney, MT. & Shah, AM., 2008, In : Journal of the American College of Cardiology. p. 1349 - 1356 8 p.

    Research output: Contribution to journalArticle

  32. NADPH oxidases as pivotal sources of ROS in cardiac disease

    Dworakowski, R., Murdoch, C. & Shah, AM., 2008, In : Nova Acta Leopoldina. p. 47 - 53 7 p.

    Research output: Contribution to journalArticle

  33. Pathophysiology of systolic heart failure. In: Chronic Heart Failure.

    Cubbon, R. (ed.), Shah, AM. (ed.) & Kearney, A. (ed.), 2008, Oxford University Press.

    Research output: Book/ReportBook

  34. Reactive oxygen species in heart failure. In: Acute Heart Failure

    Zhang, M. (ed.), Shah, AM. (ed.), Mebazaa, A. (ed.), Gheorghiade, M. (ed.), Zannad, FM. (ed.) & Parrillo, JE. (ed.), 2008, Springer.

    Research output: Book/ReportBook

  35. The effect of endothelium specific insulin resistance on endothelial function in vivo

    Duncan, E., Crossey, P., Walker, S., Anilkumar, N., Poston, L., Douglas, G., Ezzat, V., Wheatcroft, S., Shah, AM. & Kearney, MT., 2008, In : Diabetes. 57, p. 3307 - 3314 8 p.

    Research output: Contribution to journalArticle

  36. 2007
  37. Prevalence and significance of an isolated long QT interval in elite athletes

    Basavarajaiah, S., Wilson, M., Whyte, G., Shah, A., Behr, E. & Sharma, S., Dec 2007, In : European Heart Journal. 28, 23, p. 2944 - 2949 6 p.

    Research output: Contribution to journalArticle

  38. Accelerated endothelial dysfunction in mild prediabetic insulin resistance: the early role of reactive oxygen species

    Duncan, E. R., Walker, S. J., Ezzat, V. A., Wheatcroft, S. B., Li, J. M., Shah, A. M. & Kearney, M. T., Nov 2007, In : AMERICAN JOURNAL OF PHYSIOLOGY: ENDOCRINOLOGY AND METABOLISM. 293, 5, p. E1311 - E1319

    Research output: Contribution to journalArticle

  39. Involvement of NADPH oxidases in cardiac remodelling and heart failure

    Sirker, A., Zhang, M., Murdoch, C. & Shah, A. M., Oct 2007, In : American Journal of Nephrology. 27, 6, p. 649 - 660 12 p.

    Research output: Contribution to journalLiterature review

  40. . A simple thermodilution technique to assess coronary endothelium-dependent microvascular function in humans: validation and comparison with coronary flow reserve.

    Melikian, N., Kearney, MT., Thomas, MR., De Bruyne, B., Shah, AM. & MacCarthy, PA., Sep 2007, In : European Heart Journal. 28, 18, p. 2188 - 2194 7 p.

    Research output: Contribution to journalArticle

  41. A simple thermodilution technique to assess coronary endothelium-dependent humans: validation and flow reserve

    Melikian, N., Kearney, M. T., Thomas, M. R., De Bruyne, B., Shah, A. M. & MacCarthy, P. A., Sep 2007, In : European Heart Journal. 28, 18, p. 2188 - 2194 7 p.

    Research output: Contribution to journalArticle

  42. Cardiovascular function following acute volume overload for hydrodynamic gene delivery to the liver

    Sawyer, G. J., Dong, X., Whitehorne, M., Grehan, A., Seddon, M., Shah, A. M., Zhang, X. & Fabre, J. W., Aug 2007, In : Gene Therapy. 14, 16, p. 1208 - 1217 10 p.

    Research output: Contribution to journalArticle

  43. Oxidative stress and redox signalling in cardiac hypertrophy and heart failure

    Seddon, M., Looi, Y. H. & Shah, A. M., Aug 2007, In : Heart. 93, 8, p. 903 - 907 5 p.

    Research output: Contribution to journalLiterature review

  44. The association between saphenous vein endothelial function, systemic inflammation, and statin therapy in patients undergoing coronary artery bypass surgery

    Momin, A., Melikian, N., Wheatcroft, S. B., Grieve, D., John, L. C., El Gamel, A., Marrinan, M. T., Desai, J. B., Driver, C., Sherwood, R., Shah, A. M. & Kearney, M. T., Aug 2007, In : Journal of Thoracic and Cardiovascular Surgery. 134, 2, p. 335 - 341 7 p.

    Research output: Contribution to journalArticle

  45. Cardiomyocytes as effectors of nitric oxide signalling

    Seddon, M., Shah, A. M. & Casadei, B., 15 Jul 2007, In : Cardiovascular Research. 75, 2, p. 315 - 326 12 p.

    Research output: Contribution to journalLiterature review

  46. The vascular effects of metabolic impairment clusters in subjects of different ethnicities

    Rambaran, C., Chowienczyk, P., Ritter, J., Shah, A., Wilks, R., Forrester, T. & Kalra, L., Jun 2007, In : Atherosclerosis. 192, 2, p. 354 - 362 9 p.

    Research output: Contribution to journalArticle

  47. Levosimendan restores both systolic and diastolic cardiac performance in lipopolysaccharide-treated rabbits: comparison with dobutamine and milrinone

    Barraud, D., Faivre, V., Damy, T., Welschbillig, S., Gayat, E., Heymes, C., Payen, D., Shah, A. M. & Mebazaa, A., May 2007, In : Critical Care Medicine. 35, 5, p. 1376 - 1382 7 p.

    Research output: Contribution to journalArticle

  48. Asymmetric dimethylarginine and reduced nitric oxide bioavailability in young black African men

    Melikian, N., Wheatcroft, S. B., Ogah, O. S., Murphy, C., Chowienczyk, P. J., Wierzbicki, A. S., Sanders, T. A. B., Jiang, B. Y., Duncan, E. R., Shah, A. M. & Kearney, M. T., Apr 2007, In : Hypertension. 49, 4, p. 873 - 877 5 p.

    Research output: Contribution to journalArticle

  49. Vascular dysfunction and reduced circulating endothelial progenitor cells in young healthy UK South Asian men

    Murphy, C., Kanaganayagam, GS., Jiang, B., Chowienczyk, PJ., Zbinden, R., Saha, M., Rahman, S., Shah, AM., Marber, MS. & Kearney, MT., Apr 2007, In : Arteriosclerosis, Thrombosis, and Vascular Biology. 27, 4, p. 936 - 942 7 p.

    Research output: Contribution to journalArticle

  50. Role of reactive oxygen species in myocardial remodeling

    Zhang, M. & Shah, A. M., Mar 2007, In : Current Heart Failure Reports. 4, 1, p. 26 - 30 5 p.

    Research output: Contribution to journalArticle

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