King's College London

Research portal

Research Outputs

  1. 2005
  2. A Nox2 NADPH oxidase plays a central role in interstitial cardiac fibrosis induced by aldosterone in vivo

    Johar, S., Cave, A. C., Grieve, D. J. & Shah, A. M., 2005, In : Circulation (Baltimore). 112, 17, p. 322 1 p.

    Research output: Contribution to journalMeeting abstract

  3. A Nox2-containing NADPH oxidase contributes to cardiac remodeling after myocardial infarction

    Looi, Y. H., Grieve, D. J., Siva, A., Walker, S. J., Cave, A. C. & Shah, A. M., 2005, In : Circulation (Baltimore). 112, 17, p. 181 1 p.

    Research output: Contribution to journalMeeting abstract

  4. Aldosterone mediates angiotensin II induced interstitial cardiac fibrosis via a Nox2 containing NADPH oxidase

    Johar, S., Cave, A. C., Grieve, D. G. & Shah, A. M., 2005, In : Heart. 91, p. A3 - A3

    Research output: Contribution to journalMeeting abstract

  5. Clinical presentation with in-stent restenosis is not always benign

    Wheatcroft, S., MacCarthy, P., Wainwright, R., Shah, A. & Thomas, M., 2005, In : Heart. 91, p. A39 - A39

    Research output: Contribution to journalMeeting abstract

  6. Diabetes-induced overproduction of reactive oxygen species impairs post-ischemic neovascularization

    Ebrahimian, T. G., Heymes, C., You, D., Blanc-Brude, O., Waeckel, L., Vilar, J., Duriez, M., Levy, B. I., Shah, A. M. & Silvestre, J. S., 2005, In : Circulation (Baltimore). 112, 17, p. 1371 1 p.

    Research output: Contribution to journalMeeting abstract

  7. Diabetes-induced overproduction of reactive oxygen species impairs post-ischemic neovascularization

    Ebrahimian, T., Heymes, C., You, D., Blanc-Brude, O., Waeckel, L., Vilar, J., Levy, B., Shah, A. & Silvestre, J., 2005, In : Journal of Vascular Research. 42, p. 24 - 24 1 p.

    Research output: Contribution to journalMeeting abstract

  8. Endothelial function and systemic inflammation in healthy subjects with the metabolic syndrome

    Melikian, N., Chowienczyk, P., MacCarthy, P., Williams, I., Wheatcroft, S., Sherwood, R., Shah, A. & Kearney, M., 2005, In : Circulation (Baltimore). 112, 17, p. 1208 1 p.

    Research output: Contribution to journalMeeting abstract

  9. Insulin resistance is a substrate for accelerated endothelial dysfunction in middle age-studies in mice heterozygous for knockout of the insulin receptor gene (IRKO)

    Duncan, E. R., Wheatcroft, S. B., Li, J. M., Shah, A. M. & Kearney, M. T., 2005, In : Heart. 91, p. A28 - A28

    Research output: Contribution to journalMeeting abstract

  10. Leptin is a vasocillator in human saphenous vein: evidence for divergence of resistance to leptin's vascular and metabolic actions

    Momin, A. U., Shah, A., Grieve, D., Driver, C., El-Gamel, A., Desai, J., John, L., Marrinan, M., Sherwood, R. & Kearney, M., 2005, In : Journal of the American College of Cardiology. 45, 3, p. 401A - 401A

    Research output: Contribution to journalMeeting abstract

  11. Overexpression of insulin-like growth factor binding protein-2 in mice protects against the development of obesity, insulin resistance and hypertension

    Wheatcroft, S., Crossey, P., Ezzat, V., Williams, S., Modo, M., Miell, J., Shah, A. & Kearney, M., 2005, In : Atherosclerosis. 181, 1, p. S5 - S5

    Research output: Contribution to journalMeeting abstract

  12. P38-MAPK mediates the early negative inotropic effect of tumour necrosis factor-alpha (TNF). Evidence of synergy between a direct negative inotropic effect and coronary constriction

    Bellahcene, M., Cao, X. B., Layland, J., Tanno, M., Kabir, A. M., Haworth, R. S., Shah, A. M., Avkiran, M. & Marber, M. S., 2005, In : Heart. 91, p. A57 - A57

    Research output: Contribution to journalMeeting abstract

  13. Studies of leptins vascular effects in patients with coronary artery disease: Evidence for divergence of resistance to leptin's vascular and metabolic actions

    Momin, A., Grieve, D., Driver, C., El-Gamel, A., John, L., Marrinan, M., Sherwood, R., Desai, J., Shah, A. & Kearney, M., 2005, In : Circulation (Baltimore). 112, 17, p. 1054 1 p.

    Research output: Contribution to journalMeeting abstract

  14. Wnt-2 is a direct downstream target of GATA-6 regulation during the earliest stages of cardiogenesis

    Brewer, A. C., Brewer, A. C., Alexandrovich, A., Shah, A. M. & Pizzey, J. A., 2005, In : Circulation (Baltimore). 112, 17, p. 1126 1 p.

    Research output: Contribution to journalMeeting abstract

  15. 2004
  16. Peroxisome proliferator-activated receptor alpha induces NADPH oxidase activity in macrophages, leading to the generation of LDL with PPAR-alpha activation properties

    Teissier, E., Nohara, A., Chinetti, G., Paumelle, R., Cariou, B., Fruchart, J. C., Brandes, R. P., Shah, A. & Staels, B., 10 Dec 2004, In : Circulation Research. 95, 12, p. 1174 - 1182 9 p.

    Research output: Contribution to journalArticle

  17. Predicting sudden death in patients with mild to moderate chronic heart failure

    Kearney, M. T., Fox, K. A. A., Lee, A. J., Brooksby, W. P., Shah, A. M., Flapan, A., Prescott, R. J., Andrews, R., Batin, P. D., Eckberg, D. L., Gall, N., Zaman, A. G., Lindsay, H. S. & Nolan, J., Oct 2004, In : Heart. 90, 10, p. 1137 - 1143 7 p.

    Research output: Contribution to journalEditorial

  18. Preserved glucoregulation but attenuation of the vascular actions of insulin in mice heterozygous for knockout of the insulin receptor

    Wheatcroft, S. B., Shah, A. M., Li, J. M., Duncan, E., Noronha, B. T., Crossey, P. A. & Kearney, M. T., Oct 2004, In : Diabetes. 53, 10, p. 2645 - 2652 8 p.

    Research output: Contribution to journalArticle

  19. Analysis of ex vivo left ventricular pressure-volume relations in the isolated murine ejecting heart

    Grieve, D. J., Cave, A. C., Byrne, J. A., Layland, J. & Shah, A. M., Sep 2004, In : Experimental Physiology. 89, 5, p. 573 - 582 10 p.

    Research output: Contribution to journalArticle

  20. NOX-2S is a new member of the NOX family of NADPH oxidases

    Heidari, Y., Shah, A. M. & Gove, C., 23 Jun 2004, In : Gene. 335, 1-2, p. 133 - 140 8 p.

    Research output: Contribution to journalArticle

  21. Inspiratory muscle load and capacity in chronic heart failure

    Hart, N., Kearney, M. T., Pride, N. B., Green, M., Lofaso, F., Shah, A. M., Moxham, J. & Polkey, M. I., Jun 2004, In : Thorax. 59, 6, p. 477 - 482 6 p.

    Research output: Contribution to journalArticle

  22. Role of oxidative stress in cardiac remodelling after myocardial infarction

    Grieve, D. J., Byrne, J. A., Cave, A. C. & Shah, A. M., Jun 2004, In : Heart, Lung & Circulation. 13, 2, p. 132 - 138 7 p.

    Research output: Contribution to journalArticle

  23. Essential role of troponin I in the positive inotropic response to isoprenaline in mouse hearts contracting auxotonically

    Layland, J., Grieve, D. J., Cave, A. C., Sparks, E., Solar, R. J. & Shah, A. M., 1 May 2004, In : The Journal of Physiology. 556, 3, p. 835 - 847 13 p.

    Research output: Contribution to journalArticle

  24. Free radicals and redox signalling in cardiovascular disease: introduction

    Shah, A. M. & Channon, K. M., May 2004, In : Heart. 90, 5, p. 485 - 485 1 p.

    Research output: Contribution to journalEditorial

  25. Increased neuronal nitric oxide synthase-derived NO production in the failing human heart

    Damy, T., Ratajczak, P., Shah, A. M., Camors, E., Marty, I., Hasenfuss, G., Marotte, F., Samuel, J. L. & Heymes, C., 24 Apr 2004, In : The Lancet. 363, 9418, p. 1365 - 1367 3 p.

    Research output: Contribution to journalArticle

  26. Cardiac dysfunction in the Goto-Kakizaki rat - A model of type II diabetes mellitus

    El-Omar, M. M., Yang, Z. K., Phillips, A. O. & Shah, A. M., Feb 2004, In : Basic Research in Cardiology. 99, 2, p. 133 - 141 9 p.

    Research output: Contribution to journalArticle

  27. A critical role for a gp91phox-containing NADPH oxidase in interstitial cardiac fibrosis

    Johar, S., Cave, A. C., Grieve, D. J. & Shah, A. M., 2004, In : Circulation (Baltimore). 110, 17, p. 895 1 p.

    Research output: Contribution to journalMeeting abstract

  28. A gp91(phox)-containing NADPH oxidase contributes to the contractile dysfunction associated with pressure-overload cardiac hypertrophy

    Grieve, D. J., Byrne, J. A., Layland, J., Cave, A. C. & Shah, A. M., 2004, In : Heart. 90, 12

    Research output: Contribution to journalMeeting abstract

  29. A gp91-phox-containing NADPH oxidase is critical for angiotensin II-induced interstitial cardiac fibrosis

    Johar, S., Cave, A. C., Grieve, D. J. & Shah, A. M., 2004, In : Heart. 90, 12

    Research output: Contribution to journalMeeting abstract

  30. Advanced glycation end products (AGES) stimulate NADPH dependent oxidant stress in cultured neonatal rat myocytes

    Zhang, M., Kho, A. L., Shah, A. M. & Cave, A. C., 2004, In : Heart. 90, p. 075 1 p.

    Research output: Contribution to journalMeeting abstract

  31. C-reactive protein is an independent predictor of endothelial dysfunction in coronary artery disease patients optimally treated with statins: Studies in human saphenous vein

    Momin, A., Shah, A., Grieve, D., Wheatcroft, S., Driver, C., El-Gamel, A., Desai, J., John, L., Marrinan, M., Sherwood, R. & Kearney, M., 2004, In : Heart. 90, 12

    Research output: Contribution to journalMeeting abstract

  32. Confounding variables and expression of myocardial NOS - Reply

    Heymes, C., Shah, A. M. & Samuel, J. L., 2004, In : The Lancet. 364, 9442, p. 1310 - 1311 2 p.

    Research output: Contribution to journalLetter

  33. Divergent effects of a Nox2-containing NADPH oxidase on cardiac contractile function and hypertrophy after imposition of chronic pressure overload

    Grieve, D. J., Siva, A., Byrne, J. A., Cave, A. C. & Shah, A. M., 2004, In : Circulation (Baltimore). 110, 17, p. 633 1 p.

    Research output: Contribution to journalMeeting abstract

  34. Evidence for altered interleukin (IL)-18 pathway in human heart failure

    Mallat, Z., Heymes, C., Corbaz, A., Logeart, D., Alouani, S., Cohen-Solal, A., Seidler, T., Hasenfuss, G., Chvatchko, Y., Shah, A. M. & Tedgui, A., 2004, In : Faseb Journal. 18, 12

    Research output: Contribution to journalArticle

  35. Expressionof slow skeletal troponin I protects against endotoxaemia induced contractile dysfunction in mouse cardiac myocytes

    Layland, J., Cave, A. C., Grieve, D. J., Sparks, E., Solaro, R. J. & Shah, A. M., 2004, In : Heart. 90, p. 078 1 p.

    Research output: Contribution to journalMeeting abstract

  36. Free radicals and redox signalling in cardiovascular disease

    Shah, A. M. & Channon, K. M., 2004, In : Heart. 90, 5, p. 486 - 487 2 p.

    Research output: Contribution to journalArticle

  37. Knockout of inducible nitric oxide synthase protects against metabolic but not vascular dysfunction in diet-induced obesity in mice

    Noronha, B. T., Wheatcroft, S. B., Li, J. M., Shah, A. & Kearney, M. T., 2004, In : Circulation (Baltimore). 110, 17, p. 162 1 p.

    Research output: Contribution to journalMeeting abstract

  38. Leptin is an endothelial independent vasodilator in humans with coronary artery disease: Evidence for divergence of resistance to leptin's vascular and metabolic actions

    Momin, A., Shah, A., Grieve, D., Driver, C. & Sherwood, R., 2004, In : Heart. 90, 12

    Research output: Contribution to journalMeeting abstract

  39. Mice with a knockout for inducible nitric oxide synthase are protected from metabolic but not vascular dysfunction on an obesogenic diet

    Noronha, B., Wheatcroft, S. B., Li, J. M., Shah, A. M. & Kearney, M. T., 2004, In : European Heart Journal. 25, p. 104 - 104 1 p.

    Research output: Contribution to journalMeeting abstract

  40. Mice with a knockout for inducible nitric oxide synthase on an obesogenic diet are protected from metabolic but not vascular dysfunction

    Noronha, B. T., Wheatcroft, S. B., Li, J. M., Shah, A. M. & Kearney, M. T., 2004, In : Heart. 90, 12

    Research output: Contribution to journalMeeting abstract

  41. NADPH oxidase contributes to the development of contractile dysfunction during murine pressure overload cardiac hypertrophy: Pressure volume analysis of cardiac function

    Grieve, D. J., Byrne, J. A., Layland, J., Cave, A. C. & Shah, A. M., 2004, In : Heart. 90, p. 148 1 p.

    Research output: Contribution to journalMeeting abstract

  42. NADPH oxidase-dependent acute TNFa signaling and MAPK activation in endothelial cells: The role of p47phox and TRAF4

    Li, J. M., Fan, L. M. & Shah, A. M., 2004, In : Circulation (Baltimore). 110, 17, p. 158 - 158 1 p.

    Research output: Contribution to journalMeeting abstract

  43. Overexpression of IGF binding protein-2 in mice protects against insulin resistance and obesity

    Wheatcroft, S. B., Crossey, P. A., Modo, M., Williams, S., Miell, J., Ezatt, V., Shah, A. M. & Kearney, M. T., 2004, In : Heart. 90, 12

    Research output: Contribution to journalMeeting abstract

  44. Overexpression of insulin-like growth factor binding protein-2 in mice protects against the development of insulin resistance and obesity

    Wheatcroft, S., Crossey, P., Ezzat, V., Modo, M., Williams, S., Miell, J., Shah, A. & Kearney, M., 2004, In : Circulation (Baltimore). 110, 17, p. 416 1 p.

    Research output: Contribution to journalMeeting abstract

  45. Pivotal role of a gp91 phox containing NADPH oxidase in angiotensin II - Driven interstitial cardiac fibrosis

    Johar, S., Cave, A., Grieve, D. & Shah, A., 2004, In : Heart. 90, p. 096 1 p.

    Research output: Contribution to journalMeeting abstract

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