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Research Outputs

  1. 2002
  2. Predicting death due to progressive heart failure in patients with mild-to-moderate chronic heart failure

    Kearney, M. T., Fox, K. A. A., Lee, A. J., Prescott, R. J., Shah, A. M., Batin, P. D., Baig, W., Lindsay, S., Callahan, T. S., Shell, W. E., Eckberg, D. L., Zaman, A. G., Williams, S., Neilson, J. M. M. & Nolan, J., 20 Nov 2002, In : Journal of the American College of Cardiology. 40, 10, p. 1801 - 1808 8 p.

    Research output: Contribution to journalArticle

  3. Coronary artery perforation during percutaneous intervention: incidence and outcome

    Gunning, M. G., Williams, I. L., Jewitt, D. E., Shah, A. M., Wainwright, R. J. & Thomas, M. R., Nov 2002, In : Heart. 88, 5, p. 495 - 498 4 p.

    Research output: Contribution to journalArticle

  4. Activation of NADPH oxidase during progression of cardiac hypertrophy to failure

    Li, J. M., Gall, N. P., Grieve, D. J., Chen, M. & Shah, A. M., 1 Oct 2002, In : Hypertension. 40, 4, p. 477 - 484 8 p.

    Research output: Contribution to journalArticle

  5. Strain-dependent variation in vascular responses to nitric oxide in the isolated murine heart

    Bendall, J. K., Heymes, C., Wright, T. J. F., Wheatcroft, S., Grieve, D. J., Shah, A. M. & Cave, A. C., 1 Oct 2002, In : Journal of Molecular and Cellular Cardiology. 34, 10, p. 1325 - 1333 9 p.

    Research output: Contribution to journalArticle

  6. Intracellular localization and preassembly of the NADPH oxidase complex in cultured endothelial cells

    Li, J. M. & Shah, A. M., 31 May 2002, In : Journal of Biological Chemistry. 277, 22, p. 19952 - 19960 9 p.

    Research output: Contribution to journalArticle

  7. Role of cyclic GMP-denendent protein kinase in the contractile response to exogenous nitric oxide in rat cardiac myocytes

    Layland, J., Li, J. M. & Shah, A. M., 15 Apr 2002, In : The Journal of Physiology. 540, 2, p. 457 - 467 11 p.

    Research output: Contribution to journalArticle

  8. Essential role of the NADPH oxidase subunit p47(phox) in endothelial cell superoxide production in response to phorbol ester and tumor necrosis factor-alpha

    Li, J. M., Mullen, A. M., Yun, S., Wientjes, F., Brouns, G. Y., Thrasher, A. J. & Shah, A. M., 8 Feb 2002, In : Circulation Research. 90, 2, p. 143 - 150 8 p.

    Research output: Contribution to journalArticle

  9. Pivotal role of a gp91(phox)-containing NADPH oxidase in angiotensin II-induced cardiac hypertrophy in mice

    Bendall, J. K., Cave, A. C., Heymes, C., Gall, N. & Shah, A. M., 22 Jan 2002, In : Circulation (Baltimore). 105, 3, p. 293 - 296 4 p.

    Research output: Contribution to journalArticle

  10. A Gp91(phox)-containing NADPH oxidase is integrally involved in the acute cardiac adaptation to hypoxia

    Bendall, J. K., Cave, A. C. & Shah, A. M., 2002, In : Circulation (Baltimore). 106, 19, p. 744 1 p.

    Research output: Contribution to journalMeeting abstract

  11. Acute haemodynamic effects of lipolysis-induced increase of free fatty acids in healthy men

    Kearney, M. T., Chowienczyk, P. J., Brett, S. E., Sutcliffe, A., Ritter, J. M. & Shah, A. M., 2002, In : Clinical Science. 102, 5, p. 495 - 500 6 p.

    Research output: Contribution to journalArticle

  12. Angiogenesis in chronically ischaemic human heart following percutaneous myocardial revascularisation

    Cotton, J. M., Thomas, M. R., Dunmore, B. J., Salisbury, J., Shah, A. M. & Brindle, N. P. J., 2002, In : Heart. 87, 3, p. 281 - 283 3 p.

    Research output: Contribution to journalArticle

  13. Cardiac contractile dysfunction and fibrosis induced by chronic pressure overload are inhibited in gp91phox-null mice

    Grieve, D. J., Byrne, J. A., Cave, A. C. & Shah, A. M., 2002, In : The Journal of Physiology. 544, p. 42P - 43P

    Research output: Contribution to journalMeeting abstract

  14. Cardiac contractile dysfunction and fibrosis induced by chronic pressure-overload are inhibited in gp91phox-null mice

    Grieve, D. J., Byrne, J. A., Cave, A. C. & Shah, A. M., 2002, In : Circulation (Baltimore). 106, 19, p. 1170 1 p.

    Research output: Contribution to journalMeeting abstract

  15. Characteristics and outcome in patients with chronic HEART failure and preserved ejection fraction in the UK-HEART study

    MacCarthy, P. A., Kearney, M. T., Lee, A. J., Fox, K. A., Prescott, R. J., Shah, A., Eckberg, D. L., Brooksby, W. P. & Nolan, J., 2002, In : Circulation (Baltimore). 106, 19, p. 3353 1 p.

    Research output: Contribution to journalMeeting abstract

  16. Contrasting mechanisms underlie development of pressure-overload versus angiotensin II-induced hypertrophy in mice lacking the NADPH oxidase subunit gp91phox

    Byrne, J. A., Grieve, D. J., Bendall, J. K., Cave, A. & Shah, A., 2002, In : Circulation (Baltimore). 106, 19, p. 821 1 p.

    Research output: Contribution to journalMeeting abstract

  17. Contrasting mechanisms underlie the development of pressure overload versus angiotensin II-induced hypertrophy in mice lacking the NADPH oxidase subunit gp91phox

    Byrne, J. A., Grieve, D. J., Bendall, J. K., Cave, A. C. & Shah, A. M., 2002, In : The Journal of Physiology. 544, p. 42P - 42P

    Research output: Contribution to journalMeeting abstract

  18. Hepatic artery response to phenylephrine in vitro is unchanged in acute liver failure.

    Harry, R., Grieve, D., Bowles, M., Heaton, N., Mueisan, P., Rela, M., Wendon, J. & Shah, A., 2002, In : Hepatology. 36, 4, p. 6 1 p.

    Research output: Contribution to journalMeeting abstract

  19. Modulation of extracellular SOD (ecSOD) expression and activity by a GP91(phox)-containing NADPH oxidase

    Bendall, J. K., Cave, A. C., Malik, A., Wheatcroft, S. B. & Shah, A. M., 2002, In : Circulation (Baltimore). 106, 19, p. 309 1 p.

    Research output: Contribution to journalMeeting abstract

  20. Mortality, autonomic and myocardial abnormalities in chronic heart failure patients with markedly prolonged ventricular activation

    Kearney, M. T., Zaman, A. G., Eckberg, D. L., Lee, A. J., Fox, K., Prescott, R. J., Wright, D. J., Shah, A. & Nolan, J., 2002, In : Circulation (Baltimore). 106, 19, p. 2803 1 p.

    Research output: Contribution to journalMeeting abstract

  21. Obesity, atherosclerosis and the vascular endothelium: mechanisms of reduced nitric oxide bioavailability in obese humans

    Williams, I. L., Wheatcroft, S. B., Shah, A. M. & Kearney, M. T., 2002, In : INTERNATIONAL JOURNAL OF OBESITY. 26, 6, p. 754 - 764 11 p.

    Research output: Contribution to journalLiterature review

  22. Pressure-overload cardiac hypertrophy in mice with a gene-targeted disruption of the NADPH oxidase subunit gp91phox

    Byrne, J., Grieve, D. J., Bendall, J. K., Cave, A. C. & Shah, A. M., 2002, In : European Heart Journal. 23, p. 670 - 670 1 p.

    Research output: Contribution to journalMeeting abstract

  23. Splanchnic vascular hyporeactivity in human cirrhosis is related to disease severity and mediated by nitric oxide and carbon monoxide

    Harry, R., Grieve, D., Bowles, M., Heaton, N., Muiesan, P., Rela, M., Wendon, J. & Shah, A., 2002, In : Gut. 50, p. A32 - A32

    Research output: Contribution to journalMeeting abstract

  24. The effect of overexpression of IGF binding protein-1 on blood pressure homeostasis in mice

    Wheatcroft, S. B., Williams, I. L., Shah, A. M., Crossey, P. A. & Kearney, M. T., 2002, In : Journal of Hypertension. 20, p. P242

    Research output: Contribution to journalMeeting abstract

  25. 2001
  26. Impaired endothelial regulation of ventricular relaxation in cardiac hypertrophy - Role of reactive oxygen species and NADPH oxidase

    MacCarthy, P. A., Grieve, D. J., Li, J. M., Dunster, C., Kelly, F. J. & Shah, A. M., 11 Dec 2001, In : Circulation (Baltimore). 104, 24, p. 2967 - 2974 8 p.

    Research output: Contribution to journalArticle

  27. Effects of nitric oxide synthase inhibition on basal function and the force-frequency relationship in the normal and failing human heart in vivo

    Cotton, J. M., Kearney, M. T., MacCarthy, P. A., Grocott-Mason, R. M., McClean, D. R., Heymes, C., Richardson, P. J. & Shah, A. M., 6 Nov 2001, In : Circulation (Baltimore). 104, 19, p. 2318 - 2323 6 p.

    Research output: Contribution to journalArticle

  28. Cardiac contractile impairment associated with increased phosphorylation of troponin I in endotoxemic rats

    Tavernier, B., Li, J. M., El-Omar, A. M., Lanone, S., Yang, Z. K., Trayer, I. P., Mebazaa, A. & Shah, A. M., Feb 2001, In : Faseb Journal. 15, 2, p. 294 - 296 3 p.

    Research output: Contribution to journalArticle

  29. 'Flash pulmonary oedema'--a diagnosis for both the cardiologist and the nephrologist?

    Mansoor, S., Shah, A. & Scoble, J. E., 2001, In : Nephrology, Dialysis, Transplantation. 16, 7, p. 1311 - 1313 3 p.

    Research output: Contribution to journalArticle

  30. Attenuation of angiotensin II-induced cardiac hypertrophy in GP91(phox)-deficient mice.

    Bendall, J. K., Heymes, C., Cave, A. C., Gall, N. P. & Shah, A. M., 2001, In : Circulation (Baltimore). 104, 17, p. 307 - 307 1 p.

    Research output: Contribution to journalMeeting abstract

  31. Bedside predictors of progressive heart failure: 5-year follow-up of the UK-HEART study

    Kearney, M. T., Shah, A. M., Williams, S., Baig, W., Prescott, R., Andrews, R., Fox, K., Lindsay, H. S., Brooksby, P. & Nolan, J., 2001, In : European Heart Journal. 22, p. 258 - 258 1 p.

    Research output: Contribution to journalMeeting abstract

  32. Contrasting mechanisms underlie impaired NO-dependent control ol ventricular relaxation in compensated and decompensated cardiac hypertrophy

    Grieve, D. J., Gall, N. P., Maccarthy, P. A. & Shah, A. M., 2001, In : Circulation (Baltimore). 104, 17, p. 571 - 571 1 p.

    Research output: Contribution to journalMeeting abstract

  33. Divergent biological actions of coronary endothelial nitric oxide during progression of cardiac hypertrophy

    Grieve, D. J., MacCarthy, P. A., Gall, N. P., Cave, A. C. & Shah, A. M., 2001, In : Hypertension. 38, 2, p. 267 - 273 7 p.

    Research output: Contribution to journalArticle

  34. Enhanced contractile function to the calcium sensitizer EMD 57033 in cardiac myocytes from endotoxaemic rats

    Patterson, M., Layland, J., Tavernier, B. & Shah, A. M., 2001, In : European Heart Journal. 22, p. 498 - 498 1 p.

    Research output: Contribution to journalMeeting abstract

  35. Essential role of the NADPH oxidase subunit, p47phox, in PMA-stimulated O-2(-) production by mouse coronary microvascular endothelial cells

    Li, J. M., Mullen, A. M., Yun, S. & Shah, A. M., 2001, In : Circulation (Baltimore). 104, 17, p. 103 - 103 1 p.

    Research output: Contribution to journalMeeting abstract

  36. Independent predictors of sudden cardiac death in ambulant patients with chronic heart failure. 5-year follow-up of the UK-HEART study

    Kearney, M. T., Shah, A. M., Williams, S., Prescott, R., Fox, K., Flapan, A., Batin, P. D., Brooksby, P., Lindsay, H. S. & Nolan, J., 2001, In : European Heart Journal. 22, p. 532 - 532 1 p.

    Research output: Contribution to journalMeeting abstract

  37. Pro-angiogenic effect of NADPH oxidase-derived reactive oxygen species: Role in angiotensin II-induced angiogenesis

    Heymes, C., Silvestre, J. S., Duriez, M., Levy, B. I. & Shah, A., 2001, In : Circulation (Baltimore). 104, 17, p. 141 - 141 1 p.

    Research output: Contribution to journalMeeting abstract

  38. Regulation of coronary vascular tone and ventricular function by gp91(phox)-containing NADPH oxidase

    Bendall, J. K., Cave, A. C. & Shah, A. M., 2001, In : Circulation (Baltimore). 104, 17, p. 103 - 103 1 p.

    Research output: Contribution to journalMeeting abstract

  39. The physiological role of endogenous endothelin in the regulation of human coronary vasomotor tone

    MacCarthy, P. A., Pegge, N. C., Prendergast, B. D., Shah, A. M. & Groves, P. H., 2001, In : Journal of the American College of Cardiology. 37, 1, p. 137 - 143 7 p.

    Research output: Contribution to journalArticle

  40. Upregulation of cardiac NADPH oxidase expression and activity during progressive left ventricular hypertrophy

    Li, J. M., Gall, N. P., Grieve, D. J., Chen, M. Y. & Shah, A. M., 2001, In : Circulation (Baltimore). 104, 17, p. 112 - 113 2 p.

    Research output: Contribution to journalMeeting abstract

  41. Viral myocarditis and dilated cardiomyopathy: mechanisms, manifestations, and management

    Kearney, M. T., Cotton, J. M., Richardson, P. J. & Shah, A. M., 2001, In : Postgraduate Medical Journal. 77, 903, p. 4 - 10 7 p.

    Research output: Contribution to journalLiterature review

  42. 2000
  43. Effect of nitric oxide synthase inhibition on the force frequency relationship in the normal and failing human heart

    Cotton, J. M., Kearney, M. T., MacCarthy, P. A., Grocott-Mason, R. M., Richardson, P. J. & Shah, A. M., May 2000, In : European Heart Journal. 21, SUPPL. 1, p. 422 - 422 1 p.

    Research output: Contribution to journalMeeting abstract

  44. Impaired endothelium-dependent regulation of ventricular relaxation in pressure-overload cardiac hypertrophy

    MacCarthy, P. A. & Shah, A. M., 18 Apr 2000, In : Circulation (Baltimore). 101, 15, p. 1854 - 1860 7 p.

    Research output: Contribution to journalArticle

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