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Research Outputs

  1. 2017
  2. Coats, Brittney R. ; Schoenfelt, Kelly Q. ; Barbosa-Lorenzi, Valéria C. ; Peris, Eduard ; Cui, Chang ; Hoffman, Alexandria ; Zhou, Guolin ; Fernandez, Sully ; Zhai, Lijie ; Hall, Ben A. ; Haka, Abigail S. ; Shah, Ajay M. ; Reardon, Catherine A. ; Brady, Matthew J. ; Rhodes, Christopher J. ; Maxfield, Frederick R. ; Becker, Lev. / Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity. In: Cell Reports. 2017 ; Vol. 20, No. 13. pp. 3149-3161.
  3. Meitzler, Jennifer L. ; Makhlouf, Hala R. ; Antony, Smitha ; Wu, Yongzhong ; Butcher, Donna ; Jiang, Guojian ; Juhasz, Agnes ; Lu, Jiamo ; Dahan, Iris ; Jansen-Dürr, Pidder ; Pircher, Haymo ; Shah, Ajay M. ; Roy, Krishnendu ; Doroshow, James H. / Decoding NADPH Oxidase 4 Expression in Human Tumors. In: Redox Biology. 2017 ; Vol. 13. pp. 182–195.
  4. Viswambharan, Hema ; Yuldasheva, Nadira Y. ; Sengupta, Anshuman ; Imrie, Helen ; Gage, Matthew C. ; Haywood, Natalie ; Walker, Andrew M N ; Skromna, Anna ; Makova, Natallia ; Galloway, Stacey ; Shah, Pooja ; Sukumar, Piruthivi ; Porter, Karen E. ; Grant, Peter J. ; Shah, Ajay ; Santos, Celio X. ; Li, Jing ; Beech, David J. ; Wheatcroft, Stephen B. ; Cubbon, Richard M. ; Kearney, Mark T. / Selective Enhancement of Insulin Sensitivity in the Endothelium in Vivo Reveals a Novel Proatherosclerotic Signaling Loop. In: Circulation Research. 2017 ; Vol. 120, No. 5. pp. 784-798.
  5. Nakada, Yuji ; Canseco, Diana C. ; Thet, Suwannee ; Abdisalaam, Salim ; Asaithamby, Aroumougame ; Xavier Da Costa Dos Santos, Celio Santos ; Shah, Ajay M. ; Zhang, Hua ; Faber, James E. ; Kinter, Michael T. ; Szweda, Luke I. ; Xing, Chao ; Hu, Zeping ; Deberardinis, Ralph J. ; Schiattarella, Gabriele ; Hill, Joseph A. ; Oz, Orhan ; Lu, Zhigang ; Zhang, Cheng Cheng ; Kimura, Wataru ; Sadek, Hesham A. / Hypoxia induces heart regeneration in adult mice. In: NATURE. 2017 ; Vol. 541, No. 7636. pp. 222-227.
  6. Guentsch, Annemarie ; Beneke, Angelika ; Swain, Lija ; Farhat, Katja ; Nagarajan, Shunmugam ; Wielockx, Ben ; Raithatha, Kaamini ; Dudek, Jan ; Rehling, Peter ; Zieseniss, Anke ; Jatho, Aline ; Chong, Mei ; Santos, Celio X C ; Shah, Ajay M. ; Katschinski, Dörthe M. / PHD2 is a regulator for glycolytic reprogramming in macrophages. In: Molecular and Cellular Biology. 2017 ; Vol. 37, No. 1.
  7. 2016
  8. Swain, Lija ; Kesemeyer, Andrea ; Meyer-Roxlau, Stefanie ; Vettel, Christiane ; Zieseniss, Anke ; Güntsch, Annemarie ; Jatho, Aline ; Becker, Andreas ; Nanadikar, Maithily S. ; Morgan, Bruce ; Dennerlein, Sven ; Shah, Ajay ; El-Armouche, Ali ; Nikolaev, Viacheslav O. ; Katschinski, Dörthe M. / Redox Imaging Using Cardiac Myocyte-Specific Transgenic Biosensor Mice. In: Circulation Research. 2016 ; Vol. 119, No. 9. pp. 1004-1016.
  9. Trevelin, Silvia Cellone ; Dos Santos, Célio Xavier ; Ferreira, Raphael Gomes ; de Sá Lima, Larissa ; Silva, Rangel Leal ; Scavone, Cristoforo ; Curi, Rui ; Alves-Filho, José Carlos ; Cunha, Thiago Mattar ; Roxo-Júnior, Pérsio ; Cervi, Maria-Célia ; Laurindo, Francisco Rafael Martins ; Hothersall, John Stephen ; Cobb, Andrew M ; Zhang, Min ; Ivetic, Aleksandar ; Shah, Ajay M ; Lopes, Lucia Rossetti ; Cunha, Fernando Queiroz. / Apocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state. In: Scientific Reports. 2016 ; Vol. 6.
  10. Prior, Kim-Kristin ; Leisegang, Matthias S. ; Josipovic, Ivana ; Löwe, Oliver ; Shah, Ajay M. ; Weissmann, Norbert ; Schröder, Katrin ; Brandes, Ralf P. / CRISPR/Cas9-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity. In: Redox Biology. 2016 ; Vol. 9. pp. 287–295.
  11. Barallobre-Barreiro, Javier ; Gupta, Shashi K. ; Zoccarato, Anna ; Kitazume-Taneike, Rika ; Fava, Marika ; Yin, Xiaoke ; Werner, Tessa ; Hirt, Marc N. ; Zampetaki, Anna ; Viviano, Alessandro ; Chong, Mei ; Bern, Marshall ; Kourliouros, Antonios ; Domenech, Nieves ; Willeit, Peter ; Shah, Ajay M. ; Jahangiri, Marjan ; Schaefer, Liliana ; Fischer, Jens W. ; Iozzo, Renato V. ; Viner, Rosa ; Thum, Thomas ; Heineke, Joerg ; Kichler, Antoine ; Otsu, Kinya ; Mayr, Manuel. / Glycoproteomics Reveals Decorin Peptides with Anti-Myostatin Activity in Human Atrial Fibrillation. In: Circulation (Baltimore). 2016 ; Vol. 134, No. 11. pp. 817-832.
  12. Al-Jamal, Khuloud T. ; Bai, Jie ; Tzu-Wen Wang, Julie ; Protti, Andrea ; Southern, Paul ; Bogart, Lara ; Heidari, Hamed ; Li, Xinjia ; Cakebread, Andrew ; Asker, Dan ; Al-Jamal, Wafa T. ; Shah, Ajay ; Bals, Sara ; Sosabowski, Jane ; Pankhurst, Quentin A. / Magnetic Drug Targeting : Preclinical in Vivo Studies, Mathematical Modeling, and Extrapolation to Humans. In: Nano Letters. 2016 ; Vol. 16, No. 9. pp. 5652-5660.
  13. Ackland, Gareth L. ; Whittle, John ; Toner, Andrew ; Machhada, Asif ; Del Arroyo, Ana Gutierrez ; Sciuso, Alberto ; Jenkins, Nicholas ; Dyson, Alex ; Struthers, Richard ; Sneyd, J. Robert ; Minto, Gary ; Singer, Mervyn ; Shah, Ajay ; Gourine, Alexander V. / Molecular mechanisms linking autonomic dysfunction and impaired cardiac contractility in critical illness. In: Critical Care Medicine. 2016 ; Vol. 44, No. 8. pp. e614-e624.
  14. Prior, Kim Kristin ; Wittig, Ilka ; Leisegang, Matthias S. ; Groenendyk, Jody ; Weissmann, Norbert ; Michalak, Marek ; Jansen-Dürr, Pidder ; Shah, Ajay M. ; Brandes, Ralf P. / The endoplasmic reticulum chaperone calnexin is a NADPH oxidase NOX4 interacting protein. In: Journal of Biological Chemistry. 2016 ; Vol. 291, No. 13. pp. 7045-7059.
  15. Antonopoulos, Alexios S. ; Margaritis, Marios ; Verheule, Sander ; Recalde, Alice ; Sanna, Fabio ; Herdman, Laura ; Psarros, Costas ; Nasrallah, Hussein ; Coutinho, Patricia ; Akoumianakis, Ioannis ; Brewer, Alison C. ; Sayeed, Rana ; Krasopoulos, George ; Petrou, Mario ; Tarun, Akansha ; Tousoulis, Dimitris ; Shah, Ajay M. ; Casadei, Barbara ; Channon, Keith M. ; Antoniades, Charalambos. / Mutual regulation of epicardial adipose tissue and myocardial redox state by PPAR-γ/adiponectin signalling. In: Circulation Research. 2016 ; Vol. 118, No. 5. pp. 842-855.
  16. Cubbon, Richard M. ; Ruff, Naomi ; Groves, David ; Eleuteri, Antonio ; Denby, Christine ; Kearney, Lorraine ; Ali, Noman ; Walker, Andrew M N ; Jamil, Haqeel ; Gierula, John ; Gale, Chris P. ; Batin, Phillip D. ; Nolan, James ; Shah, Ajay M. ; Fox, Keith A A ; Sapsford, Robert J. ; Witte, Klaus K. ; Kearney, Mark T. / Ambulatory heart rate range predicts mode-specific mortality and hospitalisation in chronic heart failure. In: Heart. 2016 ; Vol. 102, No. 3. pp. 223-229.
  17. Jayavelu, A. K. ; Müller, J. P. ; Bauer, R. ; Böhmer, S. A. ; Lässig, J. ; Cerny-Reiterer, S. ; Sperr, W. R. ; Valent, P. ; Maurer, B. ; Moriggl, R. ; Schröder, K. ; Shah, A. M. ; Fischer, M. ; Scholl, S. ; Barth, J. ; Oellerich, T. ; Berg, T. ; Serve, H. ; Frey, S. ; Fischer, T. ; Heidel, F. H. ; Böhmer, F. D. / NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells. In: Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 2016 ; Vol. 30, No. 2. pp. 473-483.
  18. Bai, Jie ; Wang, Julie T-W ; Rubio, Noelia ; Protti, Andrea ; Heidari, Hamed ; Elgogary, Riham ; Southern, Paul ; Al-Jamal, Wafa' T ; Sosabowski, Jane ; Shah, Ajay M ; Bals, Sara ; Pankhurst, Quentin A ; Al-Jamal, Khuloud T. / Triple-Modal Imaging of Magnetically-Targeted Nanocapsules in Solid Tumours In Vivo. In: Theranostics. 2016 ; Vol. 6, No. 3. pp. 342-56.
  19. 2015
  20. Schürmann, Christoph ; Rezende, Flavia ; Kruse, Christoph ; Yasar, Yakub ; Löwe, Oliver ; Fork, Christian ; Van De Sluis, Bart ; Bremer, Rolf ; Weissmann, Norbert ; Shah, Ajay M. ; Jo, Hanjoong ; Brandes, Ralf P. ; Schröder, Katrin. / The NADPH oxidase Nox4 has anti-atherosclerotic functions. In: European Heart Journal. 2015 ; Vol. 36, No. 48. pp. 3447-3456.
  21. Zhang, Min ; Prosser, Benjamin L. ; Bamboye, Moradeke A. ; Gondim, Antonio N S ; Santos, Celio X. ; Martin, Daniel ; Ghigo, Alessandra ; Perino, Alessia ; Brewer, Alison C. ; Ward, Christopher W. ; Hirsch, Emilio ; Lederer, W. Jonathan ; Shah, Ajay M. / Contractile Function during Angiotensin-II Activation : Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation. In: Journal of the American College of Cardiology. 2015 ; Vol. 66, No. 3. pp. 261-272.
  22. Murakawa, Tomokazu ; Yamaguchi, Osamu ; Hashimoto, Ayako ; Hikoso, Shungo ; Takeda, Toshihiro ; Oka, Takafumi ; Yasui, Hiroki ; Ueda, Hiromichi ; Akazawa, Yasuhiro ; Nakayama, Hiroyuki ; Taneike, Manabu ; Misaka, Tomofumi ; Omiya, Shigemiki ; Shah, Ajay M ; Yamamoto, Akitsugu ; Nishida, Kazuhiko ; Ohsumi, Yoshinori ; Okamoto, Koji ; Sakata, Yasushi ; Otsu, Kinya. / Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation. In: Nature Communications. 2015 ; Vol. 6. pp. 7527.
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