King's College London

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Research Outputs

  1. 2017
  2. CAR: A key regulator of adhesion and inflammation

    Ortiz-Zapater, E., Santis, G. & Parsons, M., 1 Aug 2017, In : The international journal of biochemistry & cell biology. 89, p. 1-5 5 p.

    Research output: Contribution to journalShort survey

  3. 2016
  4. The transcriptional signature of active tuberculosis reflects symptom status in extra-pulmonary and pulmonary tuberculosis

    Blankley, S., Graham, C. M., Turner, J., Berry, M. P. R., Bloom, C. I., Xu, Z., Pascual, V., Banchereau, J., Chaussabel, D., Breen, R., Santis, G., Blankenship, D. M., Lipman, M. & O'Garra, A., 5 Oct 2016, In : PL o S One . 11, 10, 14 p., e0162220.

    Research output: Contribution to journalArticle

  5. Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease

    Hiley, C. T., Le Quesne, J., Santis, G., Sharpe, R., de Castro, D. G., Middleton, G. & Swanton, C., 3 Sep 2016, In : Lancet. 388, 10048, p. 1002-1011 10 p.

    Research output: Contribution to journalReview article

  6. A rare intravascular tumour diagnosed by endobronchial ultrasound

    Owen, W. T., Karampini, E., Breen, R. A., Moonim, M., Nair, A., Barrington, S. F. & Santis, G., Sep 2016, In : Thorax. 71, 9, p. 869-70 2 p.

    Research output: Contribution to journalArticle

  7. Biogenesis and function of T cell-derived exosomes

    Ventimiglia, L. N. & Alonso, M. A., 17 Aug 2016, In : Frontiers in Cell and Developmental Biology. 4, AUG, 84.

    Research output: Contribution to journalShort survey

  8. A 380-gene meta-signature of active tuberculosis compared with healthy controls

    Blankley, S., Graham, C. M., Levin, J., Turner, J., Berry, M. P. R., Bloom, C. I., Xu, Z., Pascual, V., Banchereau, J., Chaussabel, D., Breen, R., Santis, G., Blankenship, D. M., Lipman, M. & O'Garra, A., 1 Jun 2016, In : European Respiratory Journal. 47, 6, p. 1873-1876 4 p.

    Research output: Contribution to journalLetter

  9. TNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers

    Morton, P. E., Hicks, A., Ortiz-Zapater, E., Raghavan, S., Pike, R., Noble, A., Woodfin, A., Jenkins, G., Rayner, E., Santis, G. & Parsons, M., 19 May 2016, In : Scientific Reports. 6, 26321.

    Research output: Contribution to journalArticle

  10. ESCRT machinery: Damage control at the nuclear membrane

    Ventimiglia, L. N. & Martin-Serrano, J., 6 May 2016, In : CELL RESEARCH. 26, p. 641–642

    Research output: Contribution to journalArticle

  11. 2015
  12. The LungPath study: variation in the diagnostic and staging pathway for patients with lung cancer in England

    Cane, P., Linklater, K., Santis, G., Møller, H. & Peake, M., 15 Jul 2015, In : Thorax. 3 p., 206779.

    Research output: Contribution to journalArticle

  13. 2014
  14. The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility

    Kiuchi, T., Ortiz-Zapater, E., Monypenny, J., Matthews, D. R., Nguyen, L. K., Barbeau, J., Coban, O., Lawler, K., Burford, B., Rolfe, D. J., de Rinaldis, E., Dafou, D., Simpson, M. A., Woodman, N., Pinder, S., Gillett, C. E., Devauges, V., Poland, S. P., Fruhwirth, G., Marra, P. & 12 others, Boersma, Y. L., Plückthun, A., Gullick, W. J., Yarden, Y., Santis, G., Winn, M., Kholodenko, B. N., Martin-Fernandez, M. L., Parker, P., Tutt, A., Ameer-Beg, S. M. & Ng, T., 19 Aug 2014, In : Science Signaling. 7, 339, ra78.

    Research output: Contribution to journalArticle

  15. 2013
  16. ALK rearrangements in EBUS-derived transbronchial needle aspiration cytology in lung cancer

    Neat, M. J., Foot, N. J., Hicks, A., Breen, R., Wilkins, B., McLean, E. & Santis, G., Dec 2013, In : Cytopathology. 24, 6, p. 356-364 9 p.

    Research output: Contribution to journalArticle

  17. The role of Coxsackie and adenoviral receptor in TNF alpha driven inflammation in lung epithelial cells

    Hicks, A. P., Morton, P., Parsons, M. & Santis, G., Sep 2013, In : Allergy. 68, s97, p. 224-225 2 p., 536.

    Research output: Contribution to journalPoster abstract

  18. Acquired resistance to EGFR inhibition: evolution from adenocarcinoma to small cell lung cancer (SCLC)

    Moss, C., Cane, R., Mclean, E., Santis, G., Tobal, K. & Spicer, J., Jan 2013, In : Lung Cancer. 79, Supplement 1, p. S5-S5 1 p., 13.

    Research output: Contribution to journalPoster abstract

  19. 2012
  20. Routine EGFR and KRAS Mutation analysis using COLD-PCR in non-small cell lung cancer

    Pennycuick, A., Simpson, T., Crawley, D., Lal, R., Santis, G., Cane, P., Tobal, K. & Spicer, J., Aug 2012, In : International Journal of Clinical Practice. 66, 8, p. 748-752 5 p.

    Research output: Contribution to journalArticle

  21. The changing numbers and indications of mediastinoscopy procedures performed following the introduction of endobronchical ultrasound at a UK tertiary centre (vol 66, pg A140, 2011)

    Bakir, M., Breen, R., Quinn, A., King, J. & Santis, G., 2012, In : Thorax. 67, 2, p. 178 - 178 1 p.

    Research output: Contribution to journalArticle

  22. 2011
  23. Utility of endobronchial ultrasound-guided transbronchial needle aspiration in patients with tuberculous intrathoracic lymphadenopathy: a multicentre study

    Navani, N., Molyneaux, P. L., Breen, R. A., Connell, D. W., Jepson, A., Nankivell, M., Brown, J. M., Morris-Jones, S., Ng, B., Wickremasinghe, M., Lalvani, A., Rintoul, R. C., Santis, G., Kon, O. M. & Janes, S. M., Oct 2011, In : Thorax. 66, 10, p. 889-893 5 p.

    Research output: Contribution to journalArticle

  24. Screening for EGFR and KRAS mutations in endobronchial ultrasound derived transbronchial needle aspirates in non-small cell lung cancer using COLD-PCR

    Santis, G., Angell, R., Nickless, G., Quinn, A., Herbert, A., Cane, P., Spicer, J., Breen, R., McLean, E. & Tobal, K., 19 Sep 2011, In : PL o S One . 6, 9, 7 p., e25191.

    Research output: Contribution to journalArticle

  25. The challenges of integrating molecular imaging into the optimization of cancer therapy

    Patel, G. S., Kiuchi, T., Lawler, K., Ofo, E., Fruhwirth, G. O., Kelleher, M., Shamil, E., Zhang, R., Selvin, P. R., Santis, G., Spicer, J., Woodman, N., Gillett, C. E., Barber, P. R., Vojnovic, B., Kéri, G., Schaeffter, T., Goh, V., O'Doherty, M. J., Ellis, P. A. & 1 others, Ng, T., Jun 2011, In : Integrative Biology. 3, 6, p. 603 - 631 29 p.

    Research output: Contribution to journalLiterature review

  26. CAR Modulates E-Cadherin Dynamics in the Presence of Adenovirus Type 5

    Hussain, F., Morton, P. E., Snippe, M., Sullivan, J., Farmer, C., Martin-Fernandez, M. L., Parsons, M. & Santis, G., 2011, In : PL o S One . 6, 8, e23056.

    Research output: Contribution to journalArticle

  27. GENE EXPRESSION PROFILING OF ENDOBRONCHIAL ULTRASOUND-DERIVED CYTOLOGICAL ASPIRATES FROM HILAR AND MEDIASTINAL LYMPH NODES IN NSCLC

    Lee, R. W., McClean, E., Quinn, A., Breen, R., Cousins, D. & Santis, G., 2011, In : Thorax. 66, p. A28 - A29

    Research output: Contribution to journalMeeting abstract

  28. Prevalence of EGFR and K-RAS mutation status in clinical practice - relationship to patient characteristics

    Simpson, T., Pennycuick, A., Crawley, D., Tobal, K. & Santis, G., 2011, In : Lung Cancer. 71, p. S16 - S16

    Research output: Contribution to journalMeeting abstract

  29. THE CHANGING NUMBERS AND INDICATIONS OF MEDIASTINOSCOPY PROCEDURES PERFORMED FOLLOWING THE INTRODUCTION OF ENDOBRONCHIAL ULTRASOUND AT A UK TERTIARY CENTRE

    Bahir, M., Breen, R., Quinn, A., King, J. & Santis, G., 2011, In : Thorax. 66, p. A140 - A140

    Research output: Contribution to journalMeeting abstract

  30. 2010
  31. 2009
  32. Can N2 disease be predicted by FDG uptake in the primary lung tumour or hilar lymphadenopathy: preliminary results

    Szyszko, T. A., Viney, Z., O'Doherty, M. J., Nunan, T. O., Rankin, S., Santis, G., Breen, R., King, J., Lang-Lazdunski, L., Harrison-Phipps, K., Routledge, T., Cane, P., McLean, E. & Barrington, S. F., Sep 2009, In : European Journal of Nuclear Medicine and Molecular Imaging. 36, 2 Supplement, p. S332-S332 1 p., P114.

    Research output: Contribution to journalPoster abstract

  33. EGFR AND KRAS MUTATION ANALYSIS BY ENDOBRONCHIAL ULTRASOUND-GUIDED TRANSBRONCHIAL NEEDLE ASPIRATION IN NSCLC

    Santis, G., Breen, R., Quinn, A., McLean, E. & Tobal, K., 2009, In : Thorax. 64, p. A59 - A60

    Research output: Contribution to journalMeeting abstract

  34. 2008
  35. Phase II feasibility study of autologous vaccine (HSPPC-96) in patients with resectable lung cancer

    Santis, G., Senzer, N. N., Champagne, P., Isakov, L. & Teofilovici, F., 20 May 2008, In : Journal of Clinical Oncology. 26, 15S, 1 p., 7584.

    Research output: Contribution to journalArticle

  36. 2007
  37. 2006
  38. 2005
  39. Human lung draining lymph node plasmacytoid dendritic cells respond to CD40L and CpG oligodinucleotides and induce Th1 responses

    Faith, A., Peek, E., McDonald, J., Richards, DF., Santis, G. & Hawrylowicz, CM., Dec 2005, In : Immunology. 116, s1, p. 33-33 1 p., 10.4.

    Research output: Contribution to journalMeeting abstract

  40. 2004
  41. Adenovirus type-5 entry and disassembly followed in living cells by FRET, fluorescence anisotropy, and FLIM

    Martin-Fernandez, M., Longshaw, S. V., Kirby, I., Santis, G., Tobin, M. J., Clarke, D. T. & Jones, G. R., Aug 2004, In : Biophysical Journal. 87, 2, p. 1316 - 1327 12 p.

    Research output: Contribution to journalArticle

  42. 2001
  43. Adenovirus type 5 uptake by lung adenocarcinoma cells in culture correlates with Ad5 fibre binding is mediated by alpha(v)beta1 integrin and can be modulated by changes in beta1 integrin function

    Davison, E., Kirby, I., Whitehouse, J., Hart, I., Marshall, J. F. & Santis, G., Nov 2001, In : JOURNAL OF GENE MEDICINE. 3, 6, p. 550 - 559 10 p.

    Research output: Contribution to journalArticle

  44. Adenovirus type 9 fiber knob binds to the coxsackie B virus-adenovirus receptor (CAR) with lower affinity than fiber knobs of other CAR-binding adenovirus serotypes

    Kirby, I., Lord, R., Davison, E., Wickham, T. J., Roelvink, P. W., Kovesdi, I., Sutton, B. J. & Santis, G., 2001, In : Journal of Virology. 75, 15, p. 7210 - 7214 5 p.

    Research output: Contribution to journalArticle

  45. 2000
  46. Identification of contact residues and definition of the CAR-binding site of adenovirus type 5 fiber protein

    Kirby, I., Davison, E., Beavil, A. J., Soh, C. P. C., Wickham, T. J., Roelvink, P. W., Kovesdi, I., Sutton, B. J. & Santis, G., 2000, In : Journal of Virology. 74, 6, p. 2804 - 2813 10 p.

    Research output: Contribution to journalArticle

  47. Transcriptional regulation of thyroid transcription factor-1 (TTF-1) (vol 93, pg A 14, 1999)

    Whitehouse, J. L., Lee, Y. C., Bingle, C. D., Antoniou, M. & Santis, G., 2000, In : Respiratory Medicine. 94, 3, p. 295 - 295 1 p.

    Research output: Contribution to journalArticle

  48. 1999
  49. Mutations in the DG loop of adenovirus type 5 fiber knob protein abolish high-affinity binding to its cellular receptor CAR

    Kirby, I., Davison, E., Beavil, A. J., Soh, C. P., Wickham, T. J., Roelvink, P. W., Kovesdi, I., Sutton, B. J. & Santis, G., Nov 1999, In : Journal of Virology. 73, 11, p. 9508-14 7 p.

    Research output: Contribution to journalArticle

  50. Molecular determinants of adenovirus serotype 5 fibre binding to its cellular receptor CAR

    Santis, G., Legrand, V., Hong, S. S., Davison, E., Kirby, I., Imler, J. L., Finberg, R. W., Bergelson, J. M., Mehtali, M. & Boulanger, P., Jun 1999, In : Journal of General Virology. 80 ( Pt 6), p. 1519-27 9 p.

    Research output: Contribution to journalArticle

  51. Molecular biology for the critical care physician. Part II: where are we now?

    Santis, G. & Evans, T. W., May 1999, In : Critical Care Medicine. 27, 5, p. 997-1003 7 p.

    Research output: Contribution to journalArticle

  52. The human HLA-A*0201 allele, expressed in hamster cells, is not a high-affinity receptor for adenovirus type 5 fiber

    Davison, E., Kirby, I., Elliott, T. & Santis, G., May 1999, In : Journal of Virology. 73, 5, p. 4513 4517 p.

    Research output: Contribution to journalArticle

  53. 1997
  54. Integrin alpha 5 beta 1-mediated adenovirus infection is enhanced by the integrin-activating antibody TS2/16

    Davison, E., Diaz, RM., Hart, I. R., Santis, G. & Marshall, J., Aug 1997, In : Journal of Virology. 71, 8, p. 6204 6207 p.

    Research output: Contribution to journalArticle

  55. 1994
  56. Heterogeneity in the severity of cystic fibrosis and the role of CFTR gene mutations

    Dean, M. & Santis, G., Apr 1994, In : Human Genetics. 93, 4, p. 364-8 5 p.

    Research output: Contribution to journalArticle

  57. Recent advances in cystic fibrosis

    Santis, G. & Geddes, D., Apr 1994, In : Postgraduate Medical Journal. 70, 822, p. 247-51 5 p.

    Research output: Contribution to journalArticle

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