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Research Outputs

  1. 2017
  2. Randomised control trial of the effectiveness of an integrated psychosocial health promotion intervention aimed at improving health and reducing substance use in established psychosis (IMPaCT)

    Gaughran, F., Stahl, D., Ismail, K., Greenwood, K., Atakan, Z., Gardner-Sood, P., Stubbs, B., Hopkins, D., Patel, A., Lally, J., Lowe, P., Arbuthnot, M., Orr, D., Corlett, S., Eberhard, J., David, A. S., Murray, R., Smith, S., on behalf of the IMPaCT Team, Harries, B. & 31 others, Moore, S., Bonaccorso, S., Kolliakou, A., O'Brien, C., Featherman, A., Fung, C., Heslin, M., Dalemo, K., Anakwe-Umeh, S., Todd, G., Mushore, M., Mutsatsa, S., Ohlsen, R., Howes, O., Papanastasiou, E., Firdosi, M., Sallis, H., Sambath, I., Di Clemente, G., Breedvelt, J., Joseph, C., Di Forti, M., Odesanya, A., Onagbesan, D., Case, P., Musa, A., Dalton, C., Rudhra, K., Treasure, J., Murphy, C. & Kelly, J., 28 Dec 2017, In: BMC Psychiatry. 17, 1, 14 p., 413.

    Research output: Contribution to journalArticlepeer-review

  3. Acute induction of anxiety in humans by delta-9-tetrahydrocannabinol related to amygdalar cannabinoid-1 (CB1) receptors

    Bhattacharyya, S., Egerton, A., Kim, E., Rosso, L., Riano Barros, D., Hammers, A., Brammer, M., Turkheimer, F. E., Howes, O. D. & McGuire, P., 3 Nov 2017, In: Scientific Reports. 7, 1, p. 15025

    Research output: Contribution to journalArticlepeer-review

  4. Altered activation and connectivity in a hippocampal-basal ganglia-midbrain circuit during salience processing in subjects at ultra high risk for psychosis

    Winton-Brown, T., Schmidt, A., Roiser, J. P., Howes, O. D., Egerton, A., Fusar-Poli, P., Bunzeck, N., Grace, A. A., Duzel, E., Kapur, S. & McGuire, P., 3 Oct 2017, In: Translational psychiatry. 7, 10, e1245.

    Research output: Contribution to journalArticlepeer-review

  5. Cortical GABA In Subjects At Ultra-High Risk Of Psychosis: Relationship To Negative Prodromal Symptoms

    Modinos, G., Simsek, F., Horder, J., Bossong, M. G., Bonoldi, I., Azis, M., Perez, J., Broome, M., Lythgoe, D. J., Stone, J. M., Howes, O. D., Murphy, D. G., Grace, A. A., Allen, P. & McGuire, P., 19 Aug 2017, In: International Journal of Neuropsychopharmacology .

    Research output: Contribution to journalArticlepeer-review

  6. Antipsychotic treatment resistance in first-episode psychosis: prevalence, subtypes and predictors

    Demjaha, A., Lappin, J. M., Stahl, D., Patel, M. X., MacCabe, J. H., Howes, O. D., Heslin, M., Reininghaus, U. A., Donoghue, K., Lomas, B., Charalambides, M., Onyejiaka, A., Fearon, P., Jones, P., Doody, G., Morgan, C., Dazzan, P. & Murray, R. M., Aug 2017, In: Psychological Medicine. 47, 11, p. 1981-1989 9 p.

    Research output: Contribution to journalArticlepeer-review

  7. The dopamine hypothesis of Bipolar Affective Disorder: the state of the art and implications for treatment

    Ashok, A. H., Reis Marques, T. A., Jauhar, S., Nour, M., Goodwin, G. M., Young, A. & Howes, O. D., May 2017, In: Molecular Psychiatry. 22, 5, p. 666-679 14 p.

    Research output: Contribution to journalArticlepeer-review

  8. Tradução e adaptação transcultural do questionário de função sexual (SFQ) para o Português do Brasil

    Lapa, C. D. O., Rocha, G. P., Reis Marques, T., Howes, O., Smith, S., Monteiro, R. T., Zorzetti, R. & Spanemberg, L., Apr 2017, In: Trends in Psychiatry and Psychotherapy. 39, 2, p. 110-115 6 p.

    Research output: Contribution to journalArticlepeer-review

  9. Elevated Striatal Dopamine Function in Immigrants and Their Children: A Risk Mechanism for Psychosis

    Egerton, A., Howes, O. D., Houle, S., McKenzie, K., Valmaggia, L. R., Bagby, M. R., Tseng, H-H., Bloomfield, M. A. P., Kenk, M., Bhattacharyya, S., Suridjan, I., Chaddock, C. A., Winton-Brown, T. T., Allen, P., Rusjan, P., Remington, G., Meyer-Lindenberg, A., McGuire, P. K. & Mizrahi, R., 1 Mar 2017, In: Schizophrenia Bulletin. 43, 2, p. 293–301 9 p.

    Research output: Contribution to journalArticlepeer-review

  10. Treatment-Resistant Schizophrenia: Treatment Response and Resistance in Psychosis (TRRIP) Working Group Consensus Guidelines on Diagnosis and Terminology

    Howes, O. D., McCutcheon, R., Agid, O., de Bartolomeis, A., van Beveren, N. J. M., Birnbaum, M. L., Bloomfield, M. A. P., Bressan, R. A., Buchanan, R. W., Carpenter, W. T., Castle, D. J., Citrome, L., Daskalakis, Z. J., Davidson, M., Drake, R. J., Dursun, S., Ebdrup, B. H., Elkis, H., Falkai, P., Fleischacker, W. W. & 31 others, Gadelha, A., Gaughran, F., Glenthøj, B. Y., Graff-Guerrero, A., Hallak, J. E. C., Honer, W. G., Kennedy, J., Kinon, B. J., Lawrie, S. M., Lee, J., Leweke, F. M., MacCabe, J. H., McNabb, C. B., Meltzer, H., Möller, H-J., Nakajima, S., Pantelis, C., Reis Marques, T., Remington, G., Rossell, S. L., Russell, B. R., Siu, C. O., Suzuki, T., Sommer, I. E., Taylor, D., Thomas, N., Üçok, A., Umbricht, D., Walters, J. T. R., Kane, J. & Correll, C. U., 1 Mar 2017, In: The American Journal of Psychiatry. 174, 3, p. 216-229

    Research output: Contribution to journalArticlepeer-review

  11. Longitudinal alterations in motivational salience processing in ultra high-risk subjects for psychosis

    Schmidt, A., Antoniades, M., Allen, P., Egerton, A., Chaddock, C., Borgwardt, S. J., Fusar-Poli, P., Roiser, J. P., Howes, O. D. & McGuire, P., Jan 2017, In: Psychological Medicine. p. 243-254 PSM-D-16-00500R2.

    Research output: Contribution to journalArticlepeer-review

  12. The impact of Disrupted-in-Schizophrenia 1 (DISC1) on the dopaminergic system: A systematic review

    Dahoun, T., Trossbach, S. V., Brandon, N. J., Korth, C. & Howes, O. D., 2017, In: Translational psychiatry. 7, 1, e1015.

    Research output: Contribution to journalReview articlepeer-review

  13. 2016
  14. The effects of Δ9-tetrahydrocannabinol on the dopamine system

    Bloomfield, M. A. P., Ashok, A. H., Volkow, N. D. & Howes, O. D., 16 Nov 2016, In: NATURE. 539, 7629, p. 369-377 9 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  15. The role of genes, stress and dopamine in the development of schizophrenia

    Howes, O. D., Mccutcheon, R., Owen, M. J. & Murray, R., 6 Aug 2016, In: Biological psychiatry.

    Research output: Contribution to journalArticlepeer-review

  16. Stress and neuroinflammation: A systematic review of the effects of stress on microglia and the implications for mental illness

    Calcia, M. A., Bonsall, D. R., Bloomfield, P. S., Selvaraj, S., Barichello, T. & Howes, O. D., 1 May 2016, In: Psychopharmacology. 233, 9, p. 1637-1650 14 p.

    Research output: Contribution to journalReview articlepeer-review

  17. Brain-imaging studies of treatment-resistant schizophrenia: a systematic review

    Mouchlianitis, E., McCutcheon, R. & Howes, O. D., May 2016, In: The Lancet Psychiatry. 3, 5, p. 451–463

    Research output: Contribution to journalArticlepeer-review

  18. Treatment-Resistant Schizophrenia Patients Show Elevated Anterior Cingulate Cortex Glutamate Compared to Treatment-Responsive

    Mouchlianitis, E., Bloomfield, M. A. P., Law, V., Beck, K., Selvaraj, S., Rasquinha, N., Waldman, A., Turkheimer, F. E., Egerton, A., Stone, J. & Howes, O. D., May 2016, In: Schizophrenia Bulletin. 42, 3, p. 744-752

    Research output: Contribution to journalArticlepeer-review

  19. Prevalence and implications of Truman symptoms in subjects at ultra high risk for psychosis

    Madeira, L., Bonoldi, I., Rocchetti, M., Brandizzi, M., Samson, C., Azis, M., Queen, B., Bossong, M., Allen, P., Perez, J., Howes, O. D., McGuire, P. & Fusar-Poli, P., 30 Apr 2016, In: Psychiatry Research. 238, p. 270-276 7 p.

    Research output: Contribution to journalArticlepeer-review

  20. An initial investigation of abnormal bodily phenomena in subjects at ultra high risk for psychosis: Their prevalence and clinical implications

    Madeira, L., Bonoldi, I., Rocchetti, M., Samson, C., Azis, M., Queen, B., Bossong, M., Perez, J., Stone, J., Allen, P., Howes, O. D., McGuire, P., Raballo, A., Fusar-Poli, P., Ballerini, M. & Stanghellini, G., 1 Apr 2016, In: Comprehensive Psychiatry. 66, p. 39-45 7 p.

    Research output: Contribution to journalArticlepeer-review

  21. Beyond an Imperial Atlantic: Trajectories of Africans From Upper Guinea and West-Central Africa in the Early Atlantic World

    Green, T., 27 Feb 2016, In: Past and Present. 230, 1, p. 91-122 32 p.

    Research output: Contribution to journalArticlepeer-review

  22. Microglial Activity in People at Ultra High Risk of Psychosis and in Schizophrenia: An [(11)C]PBR28 PET Brain Imaging Study

    Bloomfield, P. S., Selvaraj, S., Veronese, M., Rizzo, G., Bertoldo, A., Owen, D. R., Bloomfield, M. A. P., Bonoldi, I., Kalk, N., Turkheimer, F., McGuire, P., de Paola, V. & Howes, O. D., 1 Jan 2016, In: The American Journal of Psychiatry. 173, 1, p. 44-52 9 p.

    Research output: Contribution to journalArticlepeer-review

  23. Clinical correlates of vitamin D deficiency in established psychosis

    Lally, J., Gardner-Sood, P., Firdosi, M., Iyegbe, C., Stubbs, B., Greenwood, K., Murray, R., Smith, S., Howes, O. & Gaughran, F., 2016, In: BMC Psychiatry. 16, p. 1-9 76.

    Research output: Contribution to journalArticlepeer-review

  24. 2015
  25. Autoantibodies to central nervous system neuronal surface antigens: Psychiatric symptoms and psychopharmacological implications

    Pollak, T., Beck, K., Irani, S. R., Howes, O. D., David, A. S. & McGuire, P. K., 14 Dec 2015, In: Psychopharmacology. 233, 9, p. 1605-1621 17 p.

    Research output: Contribution to journalLiterature reviewpeer-review

  26. Very Early Brain Damage Leads to Remodeling of the Working Memory System in Adulthood: A Combined fMRI/Tractography Study

    Froudist-Walsh, S., Karolis, V., Caldinelli, C., Brittain, P. J., Kroll, J., Rodríguez-Toscano, E., Tesse, M., Colquhoun, M., Howes, O., Dell'Acqua, F., Thiebaut de Schotten, M., Murray, R. M., Williams, S. C. R. & Nosarti, C., 2 Dec 2015, In: Journal of Neuroscience. 35, 48, p. 15787-99 13 p.

    Research output: Contribution to journalArticlepeer-review

  27. Prevalence of serum N-methyl-D-aspartate receptor autoantibodies in refractory psychosis

    Beck*, K. E., Lally*, J. A., Shergill, S. S., Bloomfield, M. A. P., MacCabe, J. H., Gaughran, F. P. & Howes, O., 1 Feb 2015, In: British Journal of Psychiatry. 206, 2, p. 164-165 2 p.

    Research output: Contribution to journalArticlepeer-review

  28. Memories of Violence: Slavery, The Slave Trade, and Forced Labour in Greater Senegambia in the Past and the Present

    Green, T., 2015, In: Mande Studies. 16-17, p. 169-186 18 p.

    Research output: Contribution to journalArticlepeer-review

  29. 2014
  30. Long-Term Heavy Ketamine Use is Associated with Spatial Memory Impairment and Altered Hippocampal Activation

    Morgan, C. J. A., Dodds, C. M., Furby, H., Pepper, F., Fam, J., Freeman, T. P., Hughes, E., Doeller, C., King, J., Howes, O. & Stone, J. M., 4 Dec 2014, In: Frontiers in psychiatry / Frontiers Research Foundation. 5, 11 p., 149.

    Research output: Contribution to journalArticlepeer-review

  31. Relationship Between Brain Glutamate Levels and Clinical Outcome in Individuals at Ultra high Risk of Psychosis

    Egerton, A., Stone, J., Chaddock, C. A., Barker, G. J., Bonoldi, I., Howard, R. M., Merritt, K., Allen, P., Howes, O. D., Murray, R., McLean, M. A., Lythgoe, D. J., O'Gorman, R. L. & McGuire, P., 1 Nov 2014, In: Neuropsychopharmacology. 39, 12, p. 2891-2899 9 p.

    Research output: Contribution to journalArticlepeer-review

  32. Glutamate, N-acetyl aspartate and psychotic symptoms in chronic ketamine users

    Stone, J. M., Pepper, F., Fam, J., Furby, H., Hughes, E., Morgan, C. & Howes, O. D., May 2014, In: Psychopharmacology. 231, 10, p. 2107-2116 10 p.

    Research output: Contribution to journalArticlepeer-review

  33. Does human presynaptic striatal dopamine function predict social conformity?

    Stokes, P., Benecke, A., Puraite, J., Bloomfield, M. A., Shotbolt, P., Reeves, S., Lingford-Hughes, A. R., Howes, O. & Egerton, A., Mar 2014, In: Journal of Psychopharmacology. 28, 3, p. 237-243 7 p.

    Research output: Contribution to journalArticlepeer-review

  34. 2013
  35. Neural and Behavioral Correlates of Aberrant Salience in Individuals at Risk for Psychosis

    Roiser, J. P., Howes, O. D., Chaddock, C. A., Joyce, E. M. & McGuire, P., Nov 2013, In: Schizophrenia Bulletin. 39, 6, p. 1328-1336 9 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  36. Nature or nurture? Determining the heritability of human striatal dopamine function: an [18F]-DOPA PET study

    Stokes, P., Shotbolt, P., Mehta, M. A., Turkheimer, E., Benecke, A., Copeland, C., Turkheimer, F. E., Lingford-Hughes, A. R. & Howes, O., Feb 2013, In: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 38, 3, p. 485-491 7 p.

    Research output: Contribution to journalArticlepeer-review

  37. Mind the mortality gap: The importance of metabolic function in mental illnesses

    Howes, O. D. & Beck, K., 2013, In: Psychopharmacology. 230, 1, p. 1-2 2 p.

    Research output: Contribution to journalComment/debatepeer-review

  38. 2012
  39. Transition to Psychosis Associated With Prefrontal and Subcortical Dysfunction in Ultra High-Risk Individuals

    Allen, P., Luigjes, J., Howes, O., Egerton, A., Hirao, K., Valli, I., Kambeitz, J., Fusar-Poli, P., Broome, M. & McGuire, P., Nov 2012, In: Schizophrenia Bulletin. 38, 6, p. 1268-1276 9 p., N/A.

    Research output: Contribution to journalArticlepeer-review

  40. Interpersonal sensitivity in the at-risk mental state for psychosis

    Masillo, A., Day, F., Laing, J., Howes, O., Fusar-Poli, P., Byrne, M., Bhattacharyya, S., Fiori Nastro, P., Girardi, P., McGuire, P. K. & Valmaggia, L. R., Sep 2012, In: Psychological Medicine. 42, 9, p. 1835-1845 11 p.

    Research output: Contribution to journalArticlepeer-review

  41. The nature of dopamine dysfunction in schizophrenia and what this means for treatment: Meta-analysis of Imaging Studies

    Howes, O., Kambeitz, J., Kim, E., Stahl, D., Slifstein, M., Abi-Dargham, A. & Kapur, S., 2 Apr 2012, In: Archives of General Psychiatry. 69, 8, p. 776-786 11 p.

    Research output: Contribution to journalLiterature reviewpeer-review

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