McCutcheon, R., Beck, K., Jauhar, S., & Howes, O. D. (2017). Defining the Locus of Dopaminergic Dysfunction in Schizophrenia: A Meta-analysis and Test of the Mesolimbic Hypothesis. Schizophrenia Bulletin. https://doi.org/10.1093/schbul/sbx180

Gaughran, F., Stahl, D., Ismail, K., Greenwood, K., Atakan, Z., Gardner-Sood, P., Stubbs, B., Hopkins, D., Patel, A., Lally, J., Lowe, P., Arbuthnot, M., Orr, D., Corlett, S., Eberhard, J., David, A. S., Murray, R., Smith, S., on behalf of the IMPaCT Team, ... Kelly, J. (2017). Randomised control trial of the effectiveness of an integrated psychosocial health promotion intervention aimed at improving health and reducing substance use in established psychosis (IMPaCT). BMC Psychiatry, 17(1), [413]. https://doi.org/10.1186/s12888-017-1571-0

Froudist-Walsh, S., Bloomfield, M. A., Veronese, M., Kroll, J., Karolis, V. R., Jauhar, S., Bonoldi, I., McGuire, P. K., Kapur, S., Murray, R. M., Nosarti, C., & Howes, O. (2017). The effect of perinatal brain injury on dopaminergic function and hippocampal volume in adult life. eLife, 6. https://doi.org/10.7554/eLife.29088

Bhattacharyya, S., Egerton, A., Kim, E., Rosso, L., Riano Barros, D., Hammers, A., Brammer, M., Turkheimer, F. E., Howes, O. D., & McGuire, P. (2017). Acute induction of anxiety in humans by delta-9-tetrahydrocannabinol related to amygdalar cannabinoid-1 (CB1) receptors. Scientific Reports, 7(1), 15025. https://doi.org/10.1038/s41598-017-14203-4

Murray, R. M., Bhavsar, V., Tripoli, G., & Howes, O. (2017). 30 Years on: How the Neurodevelopmental Hypothesis of Schizophrenia Morphed into the Developmental Risk Factor Model of Psychosis. Schizophrenia Bulletin, 43(6), 1190-1196. https://doi.org/10.1093/schbul/sbx121

Selvaraj, S., Bloomfield, P. S., Veronese, M., Turkheimer, F., & Howes, O. D. (2017). Brain TSPO imaging and gray matter volume in schizophrenia patients and in people at ultra high risk of psychosis: An [(11)C]PBR28 study. Schizophrenia Research. https://doi.org/10.1016/j.schres.2017.08.063

Jauhar, S., Nour, M. M., Veronese, M., Rogdaki, M., Bonoldi, I., Azis, M., Turkheimer, F., McGuire, P., Young, A. H., & Howes, O. D. (2017). A Test of the Transdiagnostic Dopamine Hypothesis of Psychosis Using Positron Emission Tomographic Imaging in Bipolar Affective Disorder and Schizophrenia. JAMA Psychiatry, 74(12), 1206-1213. https://doi.org/10.1001/jamapsychiatry.2017.2943

Winton-Brown, T., Schmidt, A., Roiser, J. P., Howes, O. D., Egerton, A., Fusar-Poli, P., Bunzeck, N., Grace, A. A., Duzel, E., Kapur, S., & McGuire, P. (2017). Altered activation and connectivity in a hippocampal-basal ganglia-midbrain circuit during salience processing in subjects at ultra high risk for psychosis. Translational psychiatry, 7(10), [e1245]. https://doi.org/10.1038/tp.2017.174

Modinos, G., Simsek, F., Horder, J., Bossong, M. G., Bonoldi, I., Azis, M., Perez, J., Broome, M., Lythgoe, D. J., Stone, J. M., Howes, O. D., Murphy, D. G., Grace, A. A., Allen, P., & McGuire, P. (2017). Cortical GABA In Subjects At Ultra-High Risk Of Psychosis: Relationship To Negative Prodromal Symptoms. International Journal of Neuropsychopharmacology . https://doi.org/10.1093/ijnp/pyx076

Demjaha, A., Lappin, J. M., Stahl, D., Patel, M. X., MacCabe, J. H., Howes, O. D., Heslin, M., Reininghaus, U. A., Donoghue, K., Lomas, B., Charalambides, M., Onyejiaka, A., Fearon, P., Jones, P., Doody, G., Morgan, C., Dazzan, P., & Murray, R. M. (2017). Antipsychotic treatment resistance in first-episode psychosis: prevalence, subtypes and predictors. Psychological Medicine, 47(11), 1981-1989. https://doi.org/10.1017/S0033291717000435

Donetto, S., Penfold, C., Anderson, J., Robert, G., & Maben, J. (2017). Nursing work and sensory experiences of hospital design: A before and after qualitative study following a move to all-single room inpatient accommodation. Health & place, 46, 121-129. https://doi.org/10.1016/j.healthplace.2017.05.001

Ashok, A. H., Mizuno, Y., Volkow, N., & Howes, O. D. (2017). Association of Stimulants With Dopaminergic Alterations in Users of Cocaine, Amphetamine, and Methamphetamine: A Systematic Review and Meta-analysis. JAMA Psychiatry. https://doi.org/10.1001/jamapsychiatry.2017.0135

Ashok, A. H., Reis Marques, T. A., Jauhar, S., Nour, M., Goodwin, G. M., Young, A., & Howes, O. D. (2017). The dopamine hypothesis of Bipolar Affective Disorder: the state of the art and implications for treatment. Molecular Psychiatry, 22(5), 666-679. https://doi.org/10.1038/mp.2017.16

Lapa, C. D. O., Rocha, G. P., Reis Marques, T., Howes, O., Smith, S., Monteiro, R. T., Zorzetti, R., & Spanemberg, L. (2017). Tradução e adaptação transcultural do questionário de função sexual (SFQ) para o Português do Brasil. Trends in Psychiatry and Psychotherapy, 39(2), 110-115. https://doi.org/10.1590/2237-6089-2016-0089

Imperatore, N., Tortora, R., De Palma, G. D., Capone, P., Gerbino, N., Donetto, S., Testa, A., Caporaso, N., & Rispo, A. (2017). Benefiacial Effects Of Gluten Free Diet In Potential Celiac Disease Of The Adult. DIGESTIVE AND LIVER DISEASE. https://doi.org/10.1016/j.dld.2017.03.009

Egerton, A., Howes, O. D., Houle, S., McKenzie, K., Valmaggia, L. R., Bagby, M. R., Tseng, H-H., Bloomfield, M. A. P., Kenk, M., Bhattacharyya, S., Suridjan, I., Chaddock, C. A., Winton-Brown, T. T., Allen, P., Rusjan, P., Remington, G., Meyer-Lindenberg, A., McGuire, P. K., & Mizrahi, R. (2017). Elevated Striatal Dopamine Function in Immigrants and Their Children: A Risk Mechanism for Psychosis. Schizophrenia Bulletin, 43(2), 293–301. https://doi.org/10.1093/schbul/sbw181

Jauhar, S., Veronese, M., Rogdaki, M., Bloomfield, M., Natesan, S., Turkheimer, F., Kapur, S., & Howes, O. D. (2017). Regulation of dopaminergic function: an [(18)F]-DOPA PET apomorphine challenge study in humans. Translational psychiatry, 7(2), e1027. https://doi.org/10.1038/tp.2016.270

Desai, A. A., Zoccatelli, G., Adams, M. A., Allen, D., Brearley, S., Rafferty, A. M., Robert, G., & Donetto, S. (2017). Taking data seriously: the value of actor-network theory in rethinking patient experience data. Journal of health services research & policy, 22(2), 134-136. https://doi.org/10.1177/1355819616685349

Schmidt, A., Antoniades, M., Allen, P., Egerton, A., Chaddock, C., Borgwardt, S. J., Fusar-Poli, P., Roiser, J. P., Howes, O. D., & McGuire, P. (2017). Longitudinal alterations in motivational salience processing in ultra high-risk subjects for psychosis. Psychological Medicine, 243-254. [PSM-D-16-00500R2]. https://doi.org/10.1017/S0033291716002439

Howes, O. D., McCutcheon, R., Agid, O., de Bartolomeis, A., van Beveren, N. J. M., Birnbaum, M. L., Bloomfield, M. A. P., Bressan, R. A., Buchanan, R. W., Carpenter, W. T., Castle, D. J., Citrome, L., Daskalakis, Z. J., Davidson, M., Drake, R. J., Dursun, S., Ebdrup, B. H., Elkis, H., Falkai, P., ... Correll, C. U. (2016). Treatment-Resistant Schizophrenia: Treatment Response and Resistance in Psychosis (TRRIP) Working Group Consensus Guidelines on Diagnosis and Terminology. The American Journal of Psychiatry, [appiajp201616050503]. https://doi.org/10.1176/appi.ajp.2016.16050503

Kim, E., Howes, O. D., Veronese, M., Beck, K., Seo, S., Park, J. W., Lee, J. S., Lee, Y-S., & Kwon, J. S. (2016). Presynaptic Dopamine Capacity in Patients with Treatment Resistant Schizophrenia Taking Clozapine: An [(18)F]DOPA PET Study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. https://doi.org/10.1038/npp.2016.258

Bloomfield, M. A. P., Ashok, A. H., Volkow, N. D., & Howes, O. D. (2016). The effects of Δ9-tetrahydrocannabinol on the dopamine system. NATURE, 539(7629), 369-377. https://doi.org/10.1038/nature20153

Murray, R. M., Quattrone, D., Natesan, S., Van Os, J., Nordentoft, M., Howes, O. D., Di Forti, M., & Taylor, D. M. (2016). Should psychiatrists be more cautious about the long-term prophylactic use of antipsychotics? British Journal of Psychiatry, 209(5), 361. https://doi.org/10.1192/bjp.bp.116.182683

Lally, J., Ajnakina, O., Di Forti, M., Trotta, A., Demjaha, A., Kolliakou, A., Mondelli, V., Reis Marques, T., Pariante, C., Dazzan, P., Shergill, S. S., Howes, O. D., David, A. S., MacCabe, J. H., Gaughran, F., & Murray, R. M. (2016). Two distinct patterns of treatment resistance: clinical predictors of treatment resistance in first-episode schizophrenia spectrum psychoses. Psychological Medicine, 46(15), 3231-3240. https://doi.org/10.1017/S0033291716002014

Egerton, A., Valmaggia, L. R., Howes, O. D., Day, F., Chaddock, C. A., Allen, P., Winton-Brown, T. T., Bloomfield, M. A. P., Bhattacharyya, S., Chilcott, J., Lappin, J. M., Murray, R. M., & McGuire, P. (2016). Adversity in childhood linked to elevated striatal dopamine function in adulthood. Schizophrenia Research, 176(2-3), 171-176. https://doi.org/10.1016/j.schres.2016.06.005

Howes, O. D., Mccutcheon, R., Owen, M. J., & Murray, R. (2016). The role of genes, stress and dopamine in the development of schizophrenia. Biological psychiatry. https://doi.org/10.1016/j.biopsych.2016.07.014

Calcia, M. A., Bonsall, D. R., Bloomfield, P. S., Selvaraj, S., Barichello, T., & Howes, O. D. (2016). Stress and neuroinflammation: A systematic review of the effects of stress on microglia and the implications for mental illness. Psychopharmacology, 233(9), 1637-1650. https://doi.org/10.1007/s00213-016-4218-9

Mouchlianitis, E., McCutcheon, R., & Howes, O. D. (2016). Brain-imaging studies of treatment-resistant schizophrenia: a systematic review. The Lancet Psychiatry, 3(5), 451–463. https://doi.org/10.1016/S2215-0366(15)00540-4

Mouchlianitis, E., Bloomfield, M. A. P., Law, V., Beck, K., Selvaraj, S., Rasquinha, N., Waldman, A., Turkheimer, F. E., Egerton, A., Stone, J., & Howes, O. D. (2016). Treatment-Resistant Schizophrenia Patients Show Elevated Anterior Cingulate Cortex Glutamate Compared to Treatment-Responsive. Schizophrenia Bulletin, 42(3), 744-752. https://doi.org/10.1093/schbul/sbv151

Madeira, L., Bonoldi, I., Rocchetti, M., Brandizzi, M., Samson, C., Azis, M., Queen, B., Bossong, M., Allen, P., Perez, J., Howes, O. D., McGuire, P., & Fusar-Poli, P. (2016). Prevalence and implications of Truman symptoms in subjects at ultra high risk for psychosis. Psychiatry Research, 238, 270-276. https://doi.org/10.1016/j.psychres.2016.02.001

Imperatore, N., Rispo, A., Capone, P., Donetto, S., De Palma, G. D., Gerbino, N., Rea, M., Caporaso, N., & Tortora, R. (2016). GLUTEN-FREE DIET DOES NOT INFLUENCE THE OCCURRENCE AND THE TH1/TH17-TH2 NATURE OF IMMUNE-MEDIATED DISEASES IN PATIENTS WITH COELIAC DISEASE. DIGESTIVE AND LIVER DISEASE. https://doi.org/10.1016/j.dld.2016.03.026

Madeira, L., Bonoldi, I., Rocchetti, M., Samson, C., Azis, M., Queen, B., Bossong, M., Perez, J., Stone, J., Allen, P., Howes, O. D., McGuire, P., Raballo, A., Fusar-Poli, P., Ballerini, M., & Stanghellini, G. (2016). An initial investigation of abnormal bodily phenomena in subjects at ultra high risk for psychosis: Their prevalence and clinical implications. Comprehensive Psychiatry, 66, 39-45. https://doi.org/10.1016/j.comppsych.2015.12.005

Lally, J., Gardner-Sood, P., Firdosi, M., Iyegbe, C., Stubbs, B., Greenwood, K., Murray, R., Smith, S., Howes, O., & Gaughran, F. (2016). Clinical correlates of vitamin D deficiency in established psychosis. BMC Psychiatry, 16, 1-9. [76]. https://doi.org/10.1186/s12888-016-0780-2

Pollak, T., Beck, K., Irani, S. R., Howes, O. D., David, A. S., & McGuire, P. K. (2015). Autoantibodies to central nervous system neuronal surface antigens: Psychiatric symptoms and psychopharmacological implications. Psychopharmacology, 233(9), 1605-1621. https://doi.org/10.1007/s00213-015-4156-y

Froudist-Walsh, S., Karolis, V., Caldinelli, C., Brittain, P. J., Kroll, J., Rodríguez-Toscano, E., Tesse, M., Colquhoun, M., Howes, O., Dell'Acqua, F., Thiebaut de Schotten, M., Murray, R. M., Williams, S. C. R., & Nosarti, C. (2015). Very Early Brain Damage Leads to Remodeling of the Working Memory System in Adulthood: A Combined fMRI/Tractography Study. Journal of Neuroscience, 35(48), 15787-99. https://doi.org/10.1523/JNEUROSCI.4769-14.2015

Iyegbe, C., Acharya, A., Lally, J., Gardner-Sood, P., Smith, L., Smith, S., Murray, R. M., Howes, O. D., & Gaughran, F. P. (2015). Does environmental confounding mask pleiotropic effects of a multiple sclerosis susceptibility variant on vitamin D in psychosis? NPJ SCHIZOPHRENIA, 1(10/28/online), [15036]. https://doi.org/10.1038/npjschz.2015.36

Donetto, S., Pierri, P., Tsianakas, V., & Robert, G. (2015). Experience based Co-design and Healthcare Improvement: Realizing Participatory design in the Public Sector. The Design Journal, 18(2), 227-248. https://doi.org/10.2752/175630615X14212498964312

Robert, G. B., & Donetto, S. (2015). Response to: ‘A ‘work smarter, not harder’ approach to improving healthcare quality’ by Hayes et al. Bmj Quality & Safety, 24(6), 407-408. https://doi.org/10.1136/bmjqs-2015-004240

Allen, P., Chaddock, C. A., Egerton, A., Howes, O., Barker, G., Bonoldi, I., Fusar-Poli, P., Murray, R., & McGuire, P. (2015). Functional Outcome in People at High Risk for Psychosis Predicted by Thalamic Glutamate Levels and Prefronto-Striatal Activation. Schizophrenia Bulletin, 41(2), 429-439. https://doi.org/10.1093/schbul/sbu115

Beck*, K. E., Lally*, J. A., Shergill, S. S., Bloomfield, M. A. P., MacCabe, J. H., Gaughran, F. P., & Howes, O. (2015). Prevalence of serum N-methyl-D-aspartate receptor autoantibodies in refractory psychosis. British Journal of Psychiatry, 206(2), 164-165. https://doi.org/10.1192/bjp.bp.113.142216

Morgan, C. J. A., Dodds, C. M., Furby, H., Pepper, F., Fam, J., Freeman, T. P., Hughes, E., Doeller, C., King, J., Howes, O., & Stone, J. M. (2014). Long-Term Heavy Ketamine Use is Associated with Spatial Memory Impairment and Altered Hippocampal Activation. Frontiers in psychiatry / Frontiers Research Foundation, 5, [149]. https://doi.org/10.3389/fpsyt.2014.00149

Stone, J. M., Pepper, F., Fam, J., Furby, H., Hughes, E., Morgan, C., & Howes, O. D. (2014). Glutamate, N-acetyl aspartate and psychotic symptoms in chronic ketamine users. Psychopharmacology, 231(10), 2107-2116. https://doi.org/10.1007/s00213-013-3354-8

Stokes, P., Benecke, A., Puraite, J., Bloomfield, M. A., Shotbolt, P., Reeves, S., Lingford-Hughes, A. R., Howes, O., & Egerton, A. (2014). Does human presynaptic striatal dopamine function predict social conformity? Journal of Psychopharmacology, 28(3), 237-243. https://doi.org/10.1177/0269881113512037

Roiser, J. P., Howes, O. D., Chaddock, C. A., Joyce, E. M., & McGuire, P. (2013). Neural and Behavioral Correlates of Aberrant Salience in Individuals at Risk for Psychosis. Schizophrenia Bulletin, 39(6), 1328-1336. [N/A]. https://doi.org/10.1093/schbul/sbs147

Stokes, P., Shotbolt, P., Mehta, M. A., Turkheimer, E., Benecke, A., Copeland, C., Turkheimer, F. E., Lingford-Hughes, A. R., & Howes, O. (2013). Nature or nurture? Determining the heritability of human striatal dopamine function: an [18F]-DOPA PET study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 38(3), 485-491. https://doi.org/10.1038/npp.2012.207

Howes, O. D., & Beck, K. (2013). Mind the mortality gap: The importance of metabolic function in mental illnesses. Psychopharmacology, 230(1), 1-2. https://doi.org/10.1007/s00213-013-3259-6

Allen, P., Luigjes, J., Howes, O., Egerton, A., Hirao, K., Valli, I., Kambeitz, J., Fusar-Poli, P., Broome, M., & McGuire, P. (2012). Transition to Psychosis Associated With Prefrontal and Subcortical Dysfunction in Ultra High-Risk Individuals. Schizophrenia Bulletin, 38(6), 1268-1276. [N/A]. https://doi.org/10.1093/schbul/sbr194

Allen, P., Chaddock, C. A., Howes, O., Egerton, A., Seal, M. L., Fusar-Poli, P., Valli, I., Day, F., & McGuire, P. K. (2012). Abnormal Relationship Between Medial Temporal Lobe and Subcortical Dopamine Function in People With an Ultra High Risk for Psychosis. Schizophrenia Bulletin, 38(5), 1040-1049. https://doi.org/10.1093/schbul/sbr017

Masillo, A., Day, F., Laing, J., Howes, O., Fusar-Poli, P., Byrne, M., Bhattacharyya, S., Fiori Nastro, P., Girardi, P., McGuire, P. K., & Valmaggia, L. R. (2012). Interpersonal sensitivity in the at-risk mental state for psychosis. Psychological Medicine, 42(9), 1835-1845. https://doi.org/10.1017/S0033291711002996

Howes, O., Kambeitz, J., Kim, E., Stahl, D., Slifstein, M., Abi-Dargham, A., & Kapur, S. (2012). The nature of dopamine dysfunction in schizophrenia and what this means for treatment: Meta-analysis of Imaging Studies. Archives of General Psychiatry, 69(8), 776-786. https://doi.org/10.1001/archgenpsychiatry.2012.169