King's College London

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Research Outputs

  1. 2010
  2. Characterization of the postconditioning effect of dexmedetomidine in mouse organotypic hippocampal slice cultures exposed to oxygen and glucose deprivation

    Dahmani, S., Rouelle, D., Gressens, P. & Mantz, J., Feb 2010, In : Anesthesiology. 112, 2, p. 373-383 11 p., N/A.

    Research output: Contribution to journalArticle

  3. Réflexions sur le recrutement des universitaires en pédiatrie

    Sarles, J., Aujard, Y., Bensman, A., Blanche, S., Clément, A., Cochat, P., Dalle, J-H., Entz-Werlé, N., Gressens, P., Labbé, A., Legall, E., Lienhardt, A., Mallet, E., Motte, J. & Tardieu, M., Feb 2010, In : Archives De Pediatrie. 17, 2, p. 109-111 3 p., N/A.

    Research output: Contribution to journalArticle

  4. Education, occupation and retirement age effects on the age of onset of Alzheimer's disease

    Lupton, M. K., Stahl, D., Archer, N., Foy, C., Poppe, M., Lovestone, S., Hollingworth, P., Williams, J., Owen, M. J., Dowzell, K., Abraham, R., Sims, R., Brayne, C., Rubinsztein, D., Gill, M., Lawlor, B., Lynch, A. & Powell, J. F., Jan 2010, In : International Journal of Geriatric Psychiatry. 25, 1, p. 30 - 36 7 p.

    Research output: Contribution to journalArticle

  5. Blood-based biomarkers of Alzheimer's disease: challenging but feasible

    Thambisetty, M. & Lovestone, S., 2010, In : Biomarkers in Medicine. 4, 1, p. 65 - 79 15 p.

    Research output: Contribution to journalLiterature review

  6. CERAD Neuropsychological Battery Total Score in Multinational Mild Cognitive Impairment and Control Populations: The AddNeuroMed Study

    Paajanen, T., Hanninen, T., Tunnard, C., Mecocci, P., Sobow, T., Tsolaki, M., Vellas, B., Lovestone, S. & Soininen, H., 2010, In : JOURNAL OF ALZHEIMERS DISEASE. 22, 4, p. 1089 - 1097 9 p.

    Research output: Contribution to journalArticle

  7. Cluster Analysis and Decision Trees of MR Imaging in Patients Suffering Alzheimer’s

    Hamou, A., Bauer, M., Lewden, B., Simmons, A., Zhang, Y., Wahlund, L-O., Tunnard, C., Kloszewska, I., Mecocci, P., Soininen, H., Tsolaki, M., Vellas, B., Muehlboeck, S., Evans, A., Spenger, C., Lovestone, S. & Gwadry-Sridhar, F., 2010, In : Intelligent systems and soft computing. Prospects, tools and applications (Lecture Notes in Artificial Intelligence). 71, p. 477-484

    Research output: Contribution to journalConference paper

  8. Combinatorial, multimodal biomarkers from large variable datasets findings from the addneuromed study

    Lovestone, S., Thambisetty, M., Kronenberg, D., Hye, A., Furney, S., Simmons, A., Guntert, A. & AddNeuroMed, C., 2010, In : International Journal of Neuropsychopharmacology . 13, p. 17 - 17 1 p.

    Research output: Contribution to journalMeeting abstract

  9. Combining MRI and MRS to Distinguish Between Alzheimer's Disease and Healthy Controls

    Westman, E., Wahlund, L-O., Foy, C., Poppe, M., Cooper, A., Murphy, D., Spenger, C., Lovestone, S. & Simmons, A., 2010, In : JOURNAL OF ALZHEIMERS DISEASE. 22, 1, p. 171 - 181 11 p.

    Research output: Contribution to journalArticle

  10. Effect of APOE ε4 allele on cortical thicknesses and volumes: the AddNeuroMed study

    Liu, Y., Paajanen, T., Westman, E., Wahlund, L-O., Simmons, A., Tunnard, C., Sobow, T., Proitsi, P., Powell, J., Mecocci, P., Tsolaki, M., Vellas, B., Muehlboeck, S., Evans, A., Spenger, C., Lovestone, S., Soininen, H. & AddNeuroMed Consortium, 2010, In : JOURNAL OF ALZHEIMERS DISEASE. 21, 3, p. 947 - 966 20 p.

    Research output: Contribution to journalArticle

  11. Genetic Evidence Implicates the Immune System and Cholesterol Metabolism in the Aetiology of Alzheimer's Disease

    Jones, L., Holmans, P. A., Hamshere, M. L., Harold, D., Moskvina, V., Ivanov, D., Pocklington, A., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Pahwa, J. S., Jones, N., Stretton, A., Morgan, A. R., Lovestone, S., Powell, J., Proitsi, P., Lupton, M. K., Brayne, C. & 62 others, Rubinsztein, D. C., Gill, M., Lawlor, B., Lynch, A., Morgan, K., Brown, K. S., Passmore, P. A., Craig, D., McGuinness, B., Todd, S., Holmes, C., Mann, D., Smith, A. D., Love, S., Kehoe, P. G., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Schuermann, B., van den Bussche, H., Heuser, I., Peters, O., Kornhuber, J., Wiltfang, J., Dichgans, M., Froelich, L., Hampel, H., Huell, M., Rujescu, D., Goate, A. M., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Singleton, A. B., Guerreiro, R., Muehleisen, T. W., Noethen, M. M., Moebus, S., Joeckel, K-H., Klopp, N., Wichmann, H. -E., Ruether, E., Carrasquillo, M. M., Pankratz, V. S., Younkin, S. G., Hardy, J., O'Donovan, M. C., Owen, M. J. & Williams, J., 2010, In : PL o S One . 5, 11, e13950.

    Research output: Contribution to journalArticle

  12. Inhibition of GSK-3 Ameliorates A beta Pathology in an Adult-Onset Drosophila Model of Alzheimer's Disease

    Sofola, O., Kerr, F., Rogers, I., Killick, R., Augustin, H., Gandy, C., Allen, M. J., Hardy, J., Lovestone, S. & Partridge, L., 2010, In : PL o S Genetics. 6, 9, e1001087.

    Research output: Contribution to journalArticle

  13. Is Alzheimer's a Disorder of Ageing and Why Don't Mice get it? The Centrality of Insulin Signalling to Alzheimer's Disease Pathology

    Lovestone, S. & Killick, R., 2010, Unknown. BERLIN: Springer, p. 129 - 152 24 p. (DIABETES, INSULIN AND ALZHEIMER'S DISEASE).

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  14. Plasma Gelsolin is Decreased and Correlates with Rate of Decline in Alzheimer's Disease

    Guentert, A., Campbell, J., Saleem, M., O'Brien, D. P., Thompson, A. J., Byers, H. L., Ward, M. A. & Lovestone, S., 2010, In : JOURNAL OF ALZHEIMERS DISEASE. 21, 2, p. 585 - 596 12 p.

    Research output: Contribution to journalArticle

  15. Proteome-Based Plasma Markers of Brain Amyloid-beta Deposition in Non-Demented Older Individuals

    Thambisetty, M., Tripaldi, R., Riddoch-Contreras, J., Hye, A., An, Y., Campbell, J., Sojkova, J., Kinsey, A., Lynham, S., Zhou, Y., Ferrucci, L., Wong, D. F., Lovestone, S. & Resnick, S. M., 2010, In : JOURNAL OF ALZHEIMERS DISEASE. 22, 4, p. 1099 - 1109 11 p.

    Research output: Contribution to journalArticle

  16. SNPs Associated with Cerebrospinal Fluid Phospho-Tau Levels Influence Rate of Decline in Alzheimer's Disease

    Cruchaga, C., Kauwe, J. S. K., Mayo, K., Spiegel, N., Bertelsen, S., Nowotny, P., Shah, A. R., Abraham, R., Hollingworth, P., Harold, D., Owen, M. M., Williams, J., Lovestone, S., Peskind, E. R., Li, G., Leverenz, J. B., Galasko, D., Morris, J. C., Fagan, A. M., Holtzman, D. M. & 1 others, Goate, A. M., 2010, In : PL o S Genetics. 6, 9, e1001101.

    Research output: Contribution to journalArticle

  17. The Thiazolidinedione Pioglitazone Increases Cholesterol Biosynthetic Gene Expression in Primary Cortical Neurons by a PPAR gamma-Independent Mechanism

    Cocks, G., Wilde, J. I., Graham, S. J., Bousgouni, V., Virley, D., Lovestone, S. & Richardson, J., 2010, In : JOURNAL OF ALZHEIMERS DISEASE. 19, 2, p. 631 - 646 16 p.

    Research output: Contribution to journalArticle

  18. 2009
  19. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

    Harold, D., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Hamshere, M. L., Pahwa, J. S., Moskvina, V., Dowzell, K., Williams, A., Jones, N., Thomas, C., Stretton, A., Morgan, A. R., Lovestone, S., Powell, J., Proitsi, P., Lupton, M. K., Brayne, C., Rubinsztein, D. C. & 66 others, Gill, M., Lawlor, B., Lynch, A., Morgan, K., Brown, K. S., Passmore, P. A., Craig, D., McGuinness, B., Todd, S., Holmes, C., Mann, D., Smith, A. D., Love, S., Kehoe, P. G., Hardy, J., Mead, S., Fox, N., Rossor, M., Collinge, J., Maier, W., Jessen, F., Schuermann, B., van den Bussche, H., Heuser, I., Kornhuber, J., Wiltfang, J., Dichgans, M., Froelich, L., Hampel, H., Huell, M., Rujescu, D., Goate, A. M., Kauwe, J. S. K., Cruchaga, C., Nowotny, P., Morris, J. C., Mayo, K., Sleegers, K., Bettens, K., Engelborghs, S., De Deyn, P. P., Van Broeckhoven, C., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Tsolaki, M., Singleton, A. B., Guerreiro, R., Muehleisen, T. W., Noethen, M. M., Moebus, S., Joeckel, K-H., Klopp, N., Wichmann, H-E., Carrasquillo, M. M., Pankratz, V. S., Younkin, S. G., Holmans, P. A., O'Donovan, M., Owen, M. J. & Williams, J., Oct 2009, In : Nature Genetics. 41, 10, p. 1088-1093 6 p.

    Research output: Contribution to journalArticle

  20. Expanding the clinical and neuroradiologic phenotype of primary microcephaly due to ASPM mutations

    Passemard, S., Titomanlio, L., Elmaleh, M., Afenjar, A., Alessandri, J-L., Andria, G., de Villemeur, T. B., Boespflug-Tanguy, O., Burglen, L., Del Giudice, E., Guimiot, F., Hyon, C., Isidor, B., Mégarbané, A., Moog, U., Odent, S., Hernandez, K., Pouvreau, N., Scala, I., Schaer, M. & 3 others, Gressens, P., Gerard, B. & Verloes, A., 22 Sep 2009, In : Neurology. 73, 12, p. 962-969 8 p., N/A.

    Research output: Contribution to journalArticle

  21. Melatonin promotes oligodendroglial maturation of injured white matter in neonatal rats

    Olivier, P., Fontaine, R. H., Loron, G., Van Steenwinckel, J., Biran, V., Massonneau, V., Kaindl, A., Dalous, J., Charriaut-Marlangue, C., Aigrot, M-S., Pansiot, J., Verney, C., Gressens, P. & Baud, O., 22 Sep 2009, In : PLoS ONE. 4, 9, p. N/A 13 p., e7128.

    Research output: Contribution to journalArticle

  22. Evidence that variation in the oligodendrocyte lineage transcription factor 2 (OLIG2) gene is associated with psychosis in Alzheimer's disease

    Sims, R., Hollingworth, P., Moskvina, V., Dowzell, K., O'Donovan, M. C., Powell, J., Lovestone, S., Brayne, C., Rubinsztein, D., Owen, M. J., Williams, J. & Abraham, R., 8 Sep 2009, In : Neuroscience Letters. 461, 1, p. 54 - 59 6 p.

    Research output: Contribution to journalArticle

  23. Autosomal recessive primary microcephalies (MCPH)

    Kaindl, A. M., Passemard, S. & Gressens, P., Sep 2009, In : JOURNAL TITLE?. 13, 5, p. 458-458 1 p., N/A.

    Research output: Contribution to journalArticle

  24. Conséquences obstétricales et pédiatriques de la consommation de cocaïne pendant la grossesse

    Lejeune, C., Simonpoli, A-M. & Gressens, P., Sep 2009, In : Archives De Pediatrie. 16, Suppl 1, p. S56-S63 8 p., N/A.

    Research output: Contribution to journalArticle

  25. Molecular mechanisms involved in injury to the preterm brain

    Kaindl, A. M., Favrais, G. & Gressens, P., Sep 2009, In : Journal of Child Neurology. 24, 9, p. 1112-1118 7 p., N/A.

    Research output: Contribution to journalArticle

  26. The AMPA receptor positive allosteric modulator, S18986, is neuroprotective against neonatal excitotoxic and inflammatory brain damage through BDNF synthesis

    Destot-Wong, K-D., Liang, K., Gupta, S. K., Favrais, G., Schwendimann, L., Pansiot, J., Baud, O., Spedding, M., Lelièvre, V., Mani, S. & Gressens, P., Sep 2009, In : Neuropharmacology. 57, 3, p. 277-286 10 p., N/A.

    Research output: Contribution to journalArticle

  27. Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice

    Killick, R., Scales, G., Leroy, K., Causevic, M., Hooper, C., Irvine, E. E., Choudhury, A. I., Drinkwater, L., Kerr, F., Al-Qassab, H., Stephenson, J., Yilmaz, Z., Giese, K. P., Brion, J-P., Withers, D. J. & Lovestone, S., 14 Aug 2009, In : Biochemical and Biophysical Research Communications. 386, 1, p. 257 - 262 6 p.

    Research output: Contribution to journalArticle

  28. The South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLAM BRC) case register: development and descriptive data

    Stewart, R., Soremekun, M., Perera, G., Broadbent, M., Callard, F., Denis, M., Hotopf, M., Thornicroft, G. & Lovestone, S., 12 Aug 2009, In : BMC Psychiatry. 9, 51.

    Research output: Contribution to journalArticle

  29. Optimized derivation and functional characterization of 5-HT neurons from human embryonic stem cells

    Kumar, M., Kaushalya, S. K., Gressens, P., Maiti, S. & Mani, S., 11 May 2009, In : STEM CELLS AND DEVELOPMENT. 18, 4, p. 615-627 13 p.

    Research output: Contribution to journalArticle

  30. A novel mouse model of Ureaplasma-induced perinatal inflammation: effects on lung and brain injury

    Normann, E., Lacaze-Masmonteil, T., Eaton, F., Schwendimann, L., Gressens, P. & Thébaud, B., Apr 2009, In : Pediatric Research. 65, 4, p. 430-436 7 p., N/A.

    Research output: Contribution to journalArticle

  31. A proposed metabolic strategy for monitoring disease progression in Alzheimer's disease

    Greenberg, N., Grassano, A., Thambisetty, M., Lovestone, S. & Legido-Quigley, C., Apr 2009, In : Electrophoresis. 30, 7, p. 1235 - 1239 5 p.

    Research output: Contribution to journalArticle

  32. Alzheimer's disease and Down's syndrome: an in vivo MRI study

    Beacher, F., Daly, E., Simmons, A., Prasher, V., Morris, R., Robinson, C., Lovestone, S., Murphy, K. & Murphy, D. G. M., Apr 2009, In : Psychological Medicine. 39, 4, p. 675 - 684 10 p.

    Research output: Contribution to journalArticle

  33. Biomarkers for Alzheimer's disease trials - biomarkers for what? A discussion paper

    Lovestone, S. & Thambisetty, M., Apr 2009, In : JOURNAL OF NUTRITION HEALTH & AGING. 13, 4, p. 334 - 336 3 p.

    Research output: Contribution to journalEditorial

  34. GAP-43 is essential for the neurotrophic effects of BDNF and positive AMPA receptor modulator S18986

    Gupta, S. K., Mishra, R., Kusum, S., Spedding, M., Meiri, K. F., Gressens, P. & Mani, S., Apr 2009, In : CELL DEATH AND DIFFERENTIATION. 16, 4, p. 624-637 14 p.

    Research output: Contribution to journalArticle

  35. Midlife Neuroticism and the age of onset of Alzheimer's disease

    Archer, N., Brown, R. G., Reeves, S., Nicholas, H., Boothby, H. & Lovestone, S., Apr 2009, In : Psychological Medicine. 39, 4, p. 665 - 673 9 p.

    Research output: Contribution to journalArticle

  36. Ontogeny of MMPs and TIMPs in the murine neocortex

    Bednarek, N., Clément, Y., Lelièvre, V., Olivier, P., Loron, G., Garnotel, R. & Gressens, P., Mar 2009, In : Pediatric Research. 65, 3, p. 296-300 5 p., N/A.

    Research output: Contribution to journalArticle

  37. The gene responsible for Dyggve-Melchior-Clausen syndrome encodes a novel peripheral membrane protein dynamically associated with the Golgi apparatus

    Dimitrov, A., Paupe, V., Gueudry, C., Sibarita, J-B., Raposo, G., Vielemeyer, O., Gilbert, T., Csaba, Z., Attie-Bitach, T., Cormier-Daire, V., Gressens, P., Rustin, P., Perez, F. & El Ghouzzi, V., 1 Feb 2009, In : Human Molecular Genetics. 18, 3, p. 440-453 14 p., N/A.

    Research output: Contribution to journalArticle

  38. The preconditioning effect of sevoflurane on the oxygen glucose-deprived hippocampal slice: the role of tyrosine kinases and duration of ischemia

    Sigaut, S., Jannier, V., Rouelle, D., Gressens, P., Mantz, J. & Dahmani, S., Feb 2009, In : Anesthesia and Analgesia. 108, 2, p. 601-608 8 p., N/A.

    Research output: Contribution to journalArticle

  39. Association Analysis of Dynamin-Binding Protein [DNMBP] on Chromosome 10q With Late Onset Alzheimer's Disease In a Large Caucasian UK Sample

    Morean, A. R., Hollingworth, P., Abraham, R., Lovestone, S., Brayne, C., Rubinsztein, D. C., Lynch, A., Lawlor, B., Gill, M., O'Donovan, M. C., Owen, M. J. & Williams, J., 5 Jan 2009, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 150B, 1, p. 61 - 64 4 p.

    Research output: Contribution to journalArticle

  40. NRSF downregulation induces neuronal differentiation in mouse embryonic stem cells

    Gupta, S. K., Gressens, P. & Mani, S., Jan 2009, In : Differentiation; research in biological diversity. 77, 1, p. 19-28 10 p., N/A.

    Research output: Contribution to journalArticle

  41. AddNeuroMed-The European Collaboration for the Discovery of Novel Biomarkers for Alzheimer's Disease

    Lovestone, S., Francis, P., Kloszewska, I., Mecocci, P., Simmons, A., Soininen, H., Spenger, C., Tsolaki, M., Vellas, B., Wahlund, L-O. & Ward, M., 2009, Unknown. OXFORD: Blackwell Publishing, Vol. 1180. p. 36 - 46 11 p. (BIOMARKERS IN BRAIN DISEASE).

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  42. Lishman’s Organic Psychiatry: A Textbook of Neuropsychiatry

    David, A. (ed.), Fleminger, S. (ed.), Kopelman, M. (ed.), Lovestone, S. (ed.) & Mellers, J. (ed.), 2009, 4th ed. Blackwell-Wiley.

    Research output: Book/ReportBook

  43. Lishman’s Organic Psychiatry: A Textbook of Neuropsychiatry (Revised 4th Ed)

    David, A. S., Fleminger, S., Kopelman, M., Lovestone, S. & Mellers, J., 2009, 4th ed. WILEY-BLACKWELL.

    Research output: Book/ReportBook

  44. MRI Measures of Alzheimer's Disease and the AddNeuroMed Study

    Simmons, A., Westrnan, E., Muehlboeck, S., Mecocci, P., Vellas, B., Tsolaki, M., Kloszewska, I., Wahlund, L-O., Soininen, H., Lovestone, S., Evans, A. & Spenger, C., 2009, Biomarkers in Brain Disease. OXFORD: Blackwell Publishing, Vol. 1180. p. 47 - 55 9 p. (BIOMARKERS IN BRAIN DISEASE).

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  45. Plasma levels of vitamin E isoforms and of coenzyme Q10 in cognitively normal, MCI and AD

    Mecocci, P., Mangialasche, F., Costanzi, E., Cecchetti, R., Soininen, H., Tsolaki, M., Kloszewska, I., Vellas, B. & Lovestone, S., 2009, In : Free Radical Research. 43, p. 55 - 56 2 p.

    Research output: Contribution to journalMeeting abstract

  46. The somatostatin 2A receptor is enriched in migrating neurons during rat and human brain development and stimulates migration and axonal outgrowth

    Le Verche, V., Kaindl, A. M., Verney, C., Csaba, Z., Peineau, S., Olivier, P., Adle-Biassette, H., Leterrier, C., Vitalis, T., Renaud, J., Dargent, B., Gressens, P. & Dournaud, P., 2009, In : PLoS ONE. 4, 5, e5509.

    Research output: Contribution to journalArticle

  47. 2008
  48. Inflammation et lésions cérébrales aiguës en anesthésie réanimation

    Degos, V., Teissier, N., Gressens, P., Puybasset, L. & Mantz, J., Dec 2008, In : Annales françaises d'anesthèsie et de rèanimation. 27, 12, p. 1008-1015 8 p.

    Research output: Contribution to journalArticle

  49. Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer's disease

    Thambisetty, M., Hye, A., Foy, C., Daly, E., Glover, A., Cooper, A., Simmons, A., Murphy, D. & Lovestone, S., Nov 2008, In : Journal of Neurology. 255, 11, p. 1712 - 1720 9 p.

    Research output: Contribution to journalArticle

  50. Vulnerability of white matter towards antenatal hypoxia is linked to a species-dependent regulation of glutamate receptor subunits

    Fontaine, R. H., Olivier, P., Massonneau, V., Leroux, P., Degos, V., Lebon, S., El Ghouzzi, V., Lelievre, V., Gressens, P. & Baud, O., 28 Oct 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 43, p. 16779-16784 6 p.

    Research output: Contribution to journalArticle

  51. Antenatal bacterial endotoxin sensitizes the immature rat brain to postnatal excitotoxic injury

    Rousset, C. I., Kassem, J., Olivier, P., Chalon, S., Gressens, P. & Saliba, E., Oct 2008, In : Journal of Neuropathology and Experimental Neurology. 67, 10, p. 994-1000 7 p.

    Research output: Contribution to journalArticle

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