King's College London

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Research Outputs

  1. 2008
  2. Glycogen Synthase Kinase-3 beta and Tau Genes Interact in Alzheimer's Disease

    Kwok, J. B. J., Loy, C. T., Hamilton, G., Lau, E., Hallupp, M., Williams, J., Owen, M. J., Broe, G. A., Tang, N., Lam, L., Powell, J. F., Lovestone, S. & Schofield, P. R., Oct 2008, In : Annals of Neurology. 64, 4, p. 446 - 454 9 p.

    Research output: Contribution to journalArticle

  3. IL-9/IL-9 receptor signaling selectively protects cortical neurons against developmental apoptosis

    Fontaine, R. H., Cases, O., Lelièvre, V., Mesplès, B., Renauld, J-C., Loron, G., Degos, V., Dournaud, P., Baud, O. & Gressens, P., Oct 2008, In : CELL DEATH AND DIFFERENTIATION. 15, 10, p. 1542-1552 11 p., N/A.

    Research output: Contribution to journalArticle

  4. L'amyotrophie spinale distale de type 1 (DSMA1 ou SMARD1)

    Kaindl, A. M., Guenther, U-P., Rudnik-Schöneborn, S., Varon, R., Zerres, K., Gressens, P., Schuelke, M., Hubner, C. & von Au, K., Oct 2008, In : Archives De Pediatrie. 15, 10, p. 1568-1572 5 p., N/A.

    Research output: Contribution to journalArticle

  5. USPIO (Ferumoxtran-10)-enhanced MRI to visualize reticuloendothelial system cells in neonatal rats: feasibility and biodistribution study

    Azoulay, R., Olivier, P., Baud, O., Verney, C., Santus, R., Robert, P., Gressens, P. & Sebag, G., Oct 2008, In : Journal of Magnetic Resonance Imaging. 28, 4, p. 1046-1052 7 p., N/A.

    Research output: Contribution to journalArticle

  6. Association analysis of 528 intra-genic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease

    Morgan, A. R., Hamilton, G., Turic, D., Jehu, L., Harold, D., Abraham, R., Hollingworth, P., Moskvina, V., Brayne, C., Rubinsztein, D. C., Lynch, A., Lawlor, B., Gill, M., O'Donovan, M., Powell, J., Lovestone, S., Williams, J. & Owen, M. J., 5 Sep 2008, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 147B, 6, p. 727 - 731 5 p.

    Research output: Contribution to journalArticle

  7. Pharmacological and genetic inhibition of NADPH oxidase does not reduce brain damage in different models of perinatal brain injury in newborn mice

    Doverhag, C., Keller, M., Karlsson, A., Hedtjarn, M., Nilsson, U., Kapeller, E., Sarkozy, G., Klimaschewski, L., Humpel, C., Hagberg, H., Simbruner, G., Gressens, P. & Savman, K., Jul 2008, In : Neurobiology of Disease. 31, 1, p. 133-144 12 p., N/A.

    Research output: Contribution to journalArticle

  8. Agomelatine, a melatonin receptor agonist with 5-HT(2C) receptor antagonist properties, protects the developing murine white matter against excitotoxicity

    Gressens, P., Schwendimann, L., Husson, I., Sarkozy, G., Mocaer, E., Vamecq, J. & Spedding, M., 24 Jun 2008, In : European Journal of Pharmacology. 588, 1, p. 58-63 6 p., N/A.

    Research output: Contribution to journalArticle

  9. Neuroprotective strategies for the neonatal brain

    Degos, V., Loron, G., Mantz, J. & Gressens, P., Jun 2008, In : Anesthesia and Analgesia. 106, 6, p. 1670-1680 11 p., N/A.

    Research output: Contribution to journalArticle

  10. Dynamics of somatostatin type 2A receptor cargoes in living hippocampal neurons

    Lelouvier, B., Tamagno, G., Kaindl, A. M., Roland, A., Lelievre, V., Le Verche, V., Loudes, C., Gressens, P., Faivre-Baumann, A., Lenkei, Z. & Dournaud, P., 23 Apr 2008, In : Journal of Neuroscience. 28, 17, p. 4336-4349 14 p., N/A.

    Research output: Contribution to journalArticle

  11. Different types of nutritional deficiencies affect different domains of spatial memory function checked in a radial arm maze

    Ranade, S. C., Rose, A., Rao, M., Gallego, J., Gressens, P. & Mani, S., 9 Apr 2008, In : Neuroscience. 152, 4, p. 859-866 8 p., N/A.

    Research output: Contribution to journalArticle

  12. Neurotoxic and neurotrophic roles of proNGF and the receptor sortilin in the adult and ageing nervous system

    Al-Shawi, R., Hafner, A., Olson, J., Chun, S., Raza, S., Thrasivoulou, C., Lovestone, S., Killick, R., Simons, P. & Cowen, T., Apr 2008, In : European Journal of Neuroscience. 27, 8, p. 2103-2114 12 p.

    Research output: Contribution to journalArticle

  13. The PPARgamma agonist FMOC-L-leucine protects both mature and immature brain

    Maurois, P., Rocchi, S., Pages, N., Bac, P., Stables, J. P., Gressens, P. & Vamecq, J., Apr 2008, In : Biomedicine and Pharmacotherapy. 62, 4, p. 259-263 5 p., N/A.

    Research output: Contribution to journalArticle

  14. Dexmedetomidine increases hippocampal phosphorylated extracellular signal-regulated protein kinase 1 and 2 content by an alpha 2-adrenoceptor-independent mechanism: evidence for the involvement of imidazoline I1 receptors

    Dahmani, S., Paris, A., Jannier, V., Hein, L., Rouelle, D., Scholz, J., Gressens, P. & Mantz, J., Mar 2008, In : Anesthesiology. 108, 3, p. 457-466 10 p., N/A.

    Research output: Contribution to journalArticle

  15. Neuregulin-1: a potential endogenous protector in perinatal brain white matter damage

    Dammann, O., Bueter, W., Leviton, A., Gressens, P. & Dammann, C. E. L., Mar 2008, In : Neonatology. 93, 3, p. 182-187 6 p., N/A.

    Research output: Contribution to journalArticle

  16. The GSK3 hypothesis of Alzheimer's disease

    Hooper, C., Killick, R. & Lovestone, S., Mar 2008, In : Journal of Neurochemistry. 104, 6, p. 1433 - 1439 7 p.

    Research output: Contribution to journalArticle

  17. Dextromethorphan is protective against sensitized N-methyl-D-aspartate receptor-mediated excitotoxic brain damage in the developing mouse brain

    Keller, M., Griesmaier, E., Auer, M., Schlager, G., Urbanek, M., Simbruner, G., Gressens, P. & Sárközy, G., Feb 2008, In : European Journal of Neuroscience. 27, 4, p. 874-883 10 p., N/A.

    Research output: Contribution to journalArticle

  18. Neuroprotection par hypothermie lors des encéphalopathies anoxo-ischémiques du nouveau-né à terme: état des connaissances

    Debillon, T., Cantagrel, S., Zupan-Simunek, V. & Gressens, P., Feb 2008, In : Archives De Pediatrie. 15, 2, p. 157-161 5 p., N/A.

    Research output: Contribution to journalArticle

  19. SORL1 variants and risk of late-onset Alzheimer's disease

    Li, Y., Rowland, C., Catanese, J., Morris, J., Lovestone, S., O'Donovan, M. C., Goate, A., Owen, M., Williams, J. & Grupe, A., Feb 2008, In : Neurobiology of Disease. 29, 2, p. 293 - 296 4 p.

    Research output: Contribution to journalArticle

  20. Positional Pathway Screen of wnt Signaling Genes in Schizophrenia: Association with DKK4

    Proitsi, P., Li, T., Hamilton, G., Di Forti, M., Collier, D., Killick, R., Chen, R., Sham, P., Murray, R., Powell, J. & Lovestone, S., 1 Jan 2008, In : Biological psychiatry. 63, 1, p. 13 - 16 4 p.

    Research output: Contribution to journalArticle

  21. Analysis of neuronal, glial, endothelial, axonal and apoptotic markers following moderate therapeutic hypothermia and anesthesia in the developing piglet brain

    Gressens, P., Dingley, J., Plaisant, F., Porter, H., Schwendimann, L., Verney, C., Tooley, J. & Thoresen, M., Jan 2008, In : Brain Pathology. 18, 1, p. 10-20 11 p., N/A.

    Research output: Contribution to journalArticle

  22. Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease

    Li, H., Wetten, S., Li, L., Jean, P. L. S., Upmanyu, R., Surh, L., Hosford, D., Barnes, M. R., Briley, J. D., Borrie, M., Coletta, N., Delisle, R., Dhalla, D., Ehm, M. G., Feldman, H. H., Fornazzari, L., Gauthier, S., Goodgame, N., Guzman, D., Hammond, S. & 28 others, Hollingworth, P., Hsiung, G. Y., Johnson, J., Kelly, D. D., Keren, R., Kertesz, A., King, K. S., Lovestone, S., Loy-English, I., Matthews, P. M., Owen, M. J., Plumpton, M., Pryse-Phillips, W., Prinjha, R. K., Richardson, J. C., Saunders, A., Slater, A. J., George-Hyslop, P. H. S., Stinnett, S. W., Swartz, J. E., Taylor, R. L., Wherrett, J., Williams, J., Yarnall, D. P., Gibson, R. A., Irizarry, M. C., Middleton, L. T. & Roses, A. D., Jan 2008, In : Archives of neurology. 65, 1, p. 45 - 53 9 p.

    Research output: Contribution to journalArticle

  23. Neurotrophins and cytokines in neuronal plasticity

    Spedding, M. & Gressens, P., 2008, In : Novartis Foundation Symposium. 289, p. 222-33; discussion 233-40 19 p.

    Research output: Contribution to journalArticle

  24. 2007
  25. Melatonin prevents learning disorders in brain-lesioned newborn mice

    Bouslama, M., Renaud, J., Olivier, P., Fontaine, R. H., Matrot, B., Gressens, P. & Gallego, J., 12 Dec 2007, In : Neuroscience. 150, 3, p. 712-719 8 p., N/A.

    Research output: Contribution to journalArticle

  26. Complement factor HY402H polymorphism is not associated with late-onset Alzheimer's disease

    Hamilton, G., Proitsi, P., Williams, J., O'Donovan, M., Owen, M., Powell, J. & Lovestone, S., Dec 2007, In : NEUROMOLECULAR MEDICINE. 9, 4, p. 331 - 334 4 p.

    Research output: Contribution to journalArticle

  27. Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease

    Hamshere, M. L., Holmans, P. A., Avramopoulos, D., Bassett, S. S., Blacker, D., Bertram, L., Wiener, H., Rochberg, N., Tanzi, R. E., Myers, A., Vrieze, F. W. D., Go, R., Fallin, D., Lovestone, S., Hardy, J., Goate, A., O'Donovan, M., Williams, J. & Owen, M. J., 15 Nov 2007, In : Human Molecular Genetics. 16, 22, p. 2703 - 2712 10 p.

    Research output: Contribution to journalArticle

  28. Diagnosing Alzheimer's disease - non-clinicians and computerised algorithms together are as accurate as the best clinical practice

    Foy, C. M. L., Nicholas, H., Hollingworth, P., Boothby, H., Willams, J., Brown, R. G., Al-Sarraj, S. & Lovestone, S., Nov 2007, In : International Journal of Geriatric Psychiatry. 22, 11, p. 1154 - 1163 10 p.

    Research output: Contribution to journalArticle

  29. Transient inhibition of astrocytogenesis in developing mouse brain following postnatal caffeine exposure

    Desfrere, L., Olivier, P., Schwendimann, L., Verney, C. & Gressens, P., Nov 2007, In : Pediatric Research. 62, 5, p. 604-609 6 p., N/A.

    Research output: Contribution to journalArticle

  30. Association studies of 23 positional/functional candidate genes on chromosome 10 in late-onset Alzheimer's disease

    Morgan, A. R., Turic, D., Jehu, L., Hamilton, G., Hollingworth, P., Moskvina, V., Jones, L., Lovestone, S., Brayne, C., Rubinsztein, D. C., Lawlor, B., Gill, M., O'Donovan, M. C., Owen, M. J. & Williams, J., 5 Sep 2007, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 144B, 6, p. 762 - 770 9 p.

    Research output: Contribution to journalArticle

  31. Neurospheres derived from human embryoid bodies treated with retinoic Acid show an increase in nestin and ngn2 expression that correlates with the proportion of tyrosine hydroxylase-positive cells

    Kumar, M., Bagchi, B., Gupta, S. K., Meena, A. S., Gressens, P. & Mani, S., 4 Sep 2007, In : STEM CELLS AND DEVELOPMENT. 16, 4, p. 667-681 15 p., N/A.

    Research output: Contribution to journalArticle

  32. Apoptosis-inducing factor deficiency induces early mitochondrial degeneration in brain followed by progressive multifocal neuropathology

    El Ghouzzi, V., Csaba, Z., Olivier, P., Lelouvier, B., Schwendimann, L., Dournaud, P., Verney, C., Rustin, P. & Gressens, P., Sep 2007, In : Journal of Neuropathology and Experimental Neurology. 66, 9, p. 838-47 10 p.

    Research output: Contribution to journalArticle

  33. Gastrointestinal dysfunction in mice with a targeted mutation in the gene encoding vasoactive intestinal polypeptide: a model for the study of intestinal ileus and Hirschsprung's disease

    Lelievre, V., Favrais, G., Abad, C., Adle-Biassette, H., Lu, Y., Germano, P. M., Cheung-Lau, G., Pisegna, J. R., Gressens, P., Lawson, G. & Waschek, J. A., Sep 2007, In : Peptides. 28, 9, p. 1688-1699 12 p., N/A.

    Research output: Contribution to journalArticle

  34. Involvement of VIP and PACAP in neonatal brain lesions generated by a combined excitotoxic/inflammatory challenge

    Favrais, G., Couvineau, A., Laburthe, M., Gressens, P. & Lelievre, V., Sep 2007, In : Peptides. 28, 9, p. 1727-1737 11 p., N/A.

    Research output: Contribution to journalArticle

  35. Neuronal damage accompanies perinatal white-matter damage

    Leviton, A. & Gressens, P., Sep 2007, In : Trends in Neurosciences. 30, 9, p. 473-478 6 p., N/A.

    Research output: Contribution to journalArticle

  36. Anti-inflammatory and immunomodulatory strategies to protect the perinatal brain

    Wolfberg, A. J., Dammann, O. & Gressens, P., Aug 2007, In : Semin Fetal Neonatal Med. 12, 4, p. 296-302 7 p., N/A.

    Research output: Contribution to journalArticle

  37. Growth factors and plasticity

    Sizonenko, S. V., Bednarek, N. & Gressens, P., Aug 2007, In : Semin Fetal Neonatal Med. 12, 4, p. 241-249 9 p., N/A.

    Research output: Contribution to journalArticle

  38. Neuroprotection of the newborn: from bench to cribside

    Saliba, E., Favrais, G. & Gressens, P., Aug 2007, In : Semin Fetal Neonatal Med. 12, 4, p. 239-240 2 p., N/A.

    Research output: Contribution to journalArticle

  39. Chronic mild stress during gestation worsens neonatal brain lesions in mice

    Rangon, C-M., Fortes, S., Lelièvre, V., Leroux, P., Plaisant, F., Joubert, C., Lanfumey, L., Cohen-Salmon, C. & Gressens, P., 11 Jul 2007, In : Journal of Neuroscience. 27, 28, p. 7532-7540 9 p., N/A.

    Research output: Contribution to journalArticle

  40. Biomarkers for disease modification trials - The innovative medicines initiative and AddNeuroMed

    Lovestone, S., Francis, P. & Strandgaard, K., Jul 2007, In : JOURNAL OF NUTRITION HEALTH & AGING. 11, 4, p. 359 - 361 3 p.

    Research output: Contribution to journalArticle

  41. Lamotrigine is neuroprotective in the energy deficiency model of MPTP intoxicated mice

    Lagrue, E., Chalon, S., Bodard, S., Saliba, E., Gressens, P. & Castelnau, P., Jul 2007, In : Pediatric Research. 62, 1, p. 14-19 6 p., N/A.

    Research output: Contribution to journalArticle

  42. Interaction between the ADAM12 and SH3MD1 genes may confer susceptibility to late-onset Alzheimer's disease

    Harold, D., Jehu, L., Turic, D., Hollingworth, P., Moore, P., Summerhayes, P., Moskvina, V., Foy, C., Archer, N., Hamilton, B. A., Lovestone, S., Powell, J., Brayne, C., Rubinsztein, D. C., Jones, L., O'Donovan, M. C., Owen, M. J. & Williams, J., 5 Jun 2007, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 144B, 4, p. 448 - 452 5 p.

    Research output: Contribution to journalArticle

  43. Plasticité postlésionnelle après lésion cérébrale traumatique

    Degos, V. & Gressens, P., Jun 2007, In : Archives De Pediatrie. 14, 6, p. 522-523 2 p.

    Research output: Contribution to journalArticle

  44. p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells

    Hooper, C., Meimaridou, E., Tavassoli, M., Melino, G., Lovestone, S. & Killick, R., 11 May 2007, In : Neuroscience Letters. 418, 1, p. 34 - 37 4 p.

    Research output: Contribution to journalArticle

  45. Entry and distribution of microglial cells in human embryonic and fetal cerebral cortex

    Monier, A., Adle-Biassette, H., Delezoide, A-L., Evrard, P., Gressens, P. & Verney, C., May 2007, In : Journal of Neuropathology and Experimental Neurology. 66, 5, p. 372-382 11 p., N/A.

    Research output: Contribution to journalArticle

  46. Lissencéphalies: aspects cliniques et génétiques

    Verloes, A., Elmaleh, M., Gonzales, M., Laquerrière, A. & Gressens, P., May 2007, In : Revue Neurologique. 163, 5, p. 533-47 15 p.

    Research output: Contribution to journalArticle

  47. T3 replacement does not prevent excitotoxic cell death but reduces developmental neuronal apoptosis in newborn mice

    Sárközy, G., Griesmaier, E., He, X., Kapelari, K., Urbanek, M., Simbruner, G., Gressens, P. & Keller, M., May 2007, In : European Journal of Paediatric Neurology. 11, 3, p. 129-135 7 p., N/A.

    Research output: Contribution to journalArticle

  48. The neuropeptide pituitary adenylate cyclase-activating polypeptide exerts anti-apoptotic and differentiating effects during neurogenesis: focus on cerebellar granule neurones and embryonic stem cells

    Falluel-Morel, A., Chafai, M., Vaudry, D., Basille, M., Cazillis, M., Aubert, N., Louiset, E., de Jouffrey, S., Le Bigot, J. F., Fournier, A., Gressens, P., Rostène, W., Vaudry, H. & Gonzalez, B. J., May 2007, In : Journal of Neuroendocrinology. 19, 5, p. 321-327 7 p., N/A.

    Research output: Contribution to journalArticle

  49. Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants

    Grupe, A., Abraham, R., Li, Y., Rowland, C., Hollingworth, P., Morgan, A., Jehu, L., Segurado, R., Stone, D., Schadt, E., Karnoub, M., Nowotny, P., Tacey, K., Catanese, J., Sninsky, J., Brayne, C., Rubinsztein, D., Gill, M., Lawlor, B., Lovestone, S. & 7 others, Holmans, P., O'Donovan, M., Morris, J. C., Thal, L., Goate, A., Owen, M. J. & Williams, J., 15 Apr 2007, In : Human Molecular Genetics. 16, 8, p. 865 - 873 9 p.

    Research output: Contribution to journalArticle

  50. Drug companies and neuroprotection of the newborn: any hope for a love story?

    Gressens, P. & Gressens, P., Apr 2007, In : Acta Paediatrica. 96, 4, p. 485-6 2 p.

    Research output: Contribution to journalArticle

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