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Research Outputs

  1. 2017
  2. CAR: A key regulator of adhesion and inflammation

    Ortiz-Zapater, E., Santis, G. & Parsons, M., 1 Aug 2017, In : The international journal of biochemistry & cell biology. 89, p. 1-5 5 p.

    Research output: Contribution to journalShort survey

  3. Inflammatory pain control by blocking oxidized phospholipid-mediated TRP channel activation

    Oehler, B., Kistner, K., Martin, C., Schiller, J., Mayer, R., Mohammadi, M., Sauer, R. S., Filipovic, M. R., Nieto, F. R., Kloka, J., Pflücke, D., Hill, K., Schaefer, M., Malcangio, M., Reeh, P. W., Brack, A., Blum, R. & Rittner, H. L., 14 Jul 2017, In : Scientific Reports. 7, 1, 5447.

    Research output: Contribution to journalArticle

  4. Drug-Induced HSP90 Inhibition Alleviates Pain in Monoarthritic Rats and Alters the Expression of New Putative Pain Players at the DRG

    Nascimento, D. S. M., Potes, C. S., Soares, M. L., Ferreira, A. C., Malcangio, M., Castro-Lopes, J. M. & Neto, F. L. M., 26 May 2017, In : Molecular Neurobiology. p. 1-17 17 p.

    Research output: Contribution to journalArticle

  5. Spinal mechanisms of neuropathic pain: Is there a P2X4-BDNF controversy?

    Malcangio, M., 17 May 2017, In : Neurobiology of Pain. 1, p. 1-5 5 p.

    Research output: Contribution to journalShort survey

  6. GABAB receptors and pain

    Malcangio, M., 11 May 2017, In : Neuropharmacology.

    Research output: Contribution to journalArticle

  7. Exosomal cargo including microRNA regulates sensory neuron to macrophage communication after nerve trauma

    Simeoli, R., Montague, K., Jones, H. R., Castaldi, L., Chambers, D., Kelleher, J. H., Vacca, V., Pitcher, T., Grist, J., Al-Ahdal, H., Wong, L-F., Perretti, M., Lai, J., Mouritzen, P., Heppenstall, P. & Malcangio, M., 2017, In : Nature Communications. 8, 1, p. 1778 1 p.

    Research output: Contribution to journalArticle

  8. 2016
  9. The transcriptional signature of active tuberculosis reflects symptom status in extra-pulmonary and pulmonary tuberculosis

    Blankley, S., Graham, C. M., Turner, J., Berry, M. P. R., Bloom, C. I., Xu, Z., Pascual, V., Banchereau, J., Chaussabel, D., Breen, R., Santis, G., Blankenship, D. M., Lipman, M. & O'Garra, A., 5 Oct 2016, In : PL o S One . 11, 10, 14 p., e0162220.

    Research output: Contribution to journalArticle

  10. Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease

    Hiley, C. T., Le Quesne, J., Santis, G., Sharpe, R., de Castro, D. G., Middleton, G. & Swanton, C., 3 Sep 2016, In : Lancet. 388, 10048, p. 1002-1011 10 p.

    Research output: Contribution to journalReview article

  11. A rare intravascular tumour diagnosed by endobronchial ultrasound

    Owen, W. T., Karampini, E., Breen, R. A., Moonim, M., Nair, A., Barrington, S. F. & Santis, G., Sep 2016, In : Thorax. 71, 9, p. 869-70 2 p.

    Research output: Contribution to journalArticle

  12. A 380-gene meta-signature of active tuberculosis compared with healthy controls

    Blankley, S., Graham, C. M., Levin, J., Turner, J., Berry, M. P. R., Bloom, C. I., Xu, Z., Pascual, V., Banchereau, J., Chaussabel, D., Breen, R., Santis, G., Blankenship, D. M., Lipman, M. & O'Garra, A., 1 Jun 2016, In : European Respiratory Journal. 47, 6, p. 1873-1876 4 p.

    Research output: Contribution to journalLetter

  13. TNFα promotes CAR-dependent migration of leukocytes across epithelial monolayers

    Morton, P. E., Hicks, A., Ortiz-Zapater, E., Raghavan, S., Pike, R., Noble, A., Woodfin, A., Jenkins, G., Rayner, E., Santis, G. & Parsons, M., 19 May 2016, In : Scientific Reports. 6, 26321.

    Research output: Contribution to journalArticle

  14. The monoiodoacetate model of osteoarthritis pain in the mouse

    Pitcher, T., Sousa-Valente, J. & Malcangio, M., 16 May 2016, In : Journal of Visualized Experiments. 2016, 111, e53746.

    Research output: Contribution to journalArticle

  15. Microglia and chronic pain

    Malcangio, M., May 2016, 2 p.

    Research output: Other contribution

  16. Neuron-immune mechanisms contribute to pain in early stages of arthritis

    Nieto, F. R., Clark, A. K., Grist, J., Hathway, G. J., Chapman, V. & Malcangio, M., 29 Apr 2016, In : Journal of neuroinflammation. 13, 1, 96.

    Research output: Contribution to journalArticle

  17. Recent advances in neuroimmune interactions in neuropathic pain: The role of microglia

    Old, E. A., Nicol, L. S. C. & Malcangio, M., 5 Mar 2016, An Introduction to Pain and Nervous System Disorders. WILEY-BLACKWELL, p. 123-147 25 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  18. Role of extracellular calcitonin gene-related peptide in spinal cord mechanisms of cancer-induced bone pain

    Hansen, R. R., Vacca, V., Pitcher, T., Clark, A. K. & Malcangio, M., 1 Mar 2016, In : Pain. 157, 3, p. 666-676 11 p.

    Research output: Contribution to journalArticle

  19. 2015
  20. The LungPath study: variation in the diagnostic and staging pathway for patients with lung cancer in England

    Cane, P., Linklater, K., Santis, G., Møller, H. & Peake, M., 15 Jul 2015, In : Thorax. 3 p., 206779.

    Research output: Contribution to journalArticle

  21. Development of monosodium acetate-induced osteoarthritis and inflammatory pain in ageing mice

    Ogbonna, A. C., Clark, A. K. & Malcangio, M., 28 Jun 2015, In : AGE. 37, 3, 54.

    Research output: Contribution to journalArticle

  22. The role of G-protein receptor 84 in experimental neuropathic pain

    Nicol, L. S. C., Dawes, J. M., Russa, F. L., Didangelos, A., Clark, A. K., Gentry, C., Grist, J., Davies, J. B., Malcangio, M. & McMahon, S. B., 10 Jun 2015, In : Journal of Neuroscience. 35, 23, p. 8959-8969 11 p.

    Research output: Contribution to journalArticle

  23. Calcitonin gene-related peptide-expressing sensory neurons and spinal microglial reactivity contribute to pain states in collagen-induced arthritis

    Nieto, F. R., Clark, A. K., Grist, J., Chapman, V. & Malcangio, M., Jun 2015, In : Arthritis and Rheumatology. 67, 6, p. 1668-1677 10 p.

    Research output: Contribution to journalArticle

  24. Selective activation of microglia facilitates synaptic strength

    Clark, A. K., Gruber-Schoffnegger, D., Drdla-Schutting, R., Gerhold, K. J., Malcangio, M. & Sandkühler, J., 18 Mar 2015, In : Journal of Neuroscience. 35, 11, p. 4552-4570 19 p.

    Research output: Contribution to journalArticle

  25. The role of glia in the spinal cord in neuropathic and inflammatory pain

    Amy Old, E., Clark, A. K. & Malcangio, M., Jan 2015, Handbook of Experimental Pharmacology. Vol. 227. p. 145-170 26 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  26. Chronic pain: New insights in molecular and cellular mechanisms

    Luongo, L., Malcangio, M., Salvemini, D. & Starowicz, K., 2015, In : BioMed Research International. 2015, 676725.

    Research output: Contribution to journalArticle

  27. 2014
  28. The ErbB4 CYT2 variant protects EGFR from ligand-induced degradation to enhance cancer cell motility

    Kiuchi, T., Ortiz-Zapater, E., Monypenny, J., Matthews, D. R., Nguyen, L. K., Barbeau, J., Coban, O., Lawler, K., Burford, B., Rolfe, D. J., de Rinaldis, E., Dafou, D., Simpson, M. A., Woodman, N., Pinder, S., Gillett, C. E., Devauges, V., Poland, S. P., Fruhwirth, G., Marra, P. & 12 others, Boersma, Y. L., Plückthun, A., Gullick, W. J., Yarden, Y., Santis, G., Winn, M., Kholodenko, B. N., Martin-Fernandez, M. L., Parker, P., Tutt, A., Ameer-Beg, S. M. & Ng, T., 19 Aug 2014, In : Science Signaling. 7, 339, ra78.

    Research output: Contribution to journalArticle

  29. Fractalkine/CX3CR1 signaling during neuropathic pain

    Clark, A. K. & Malcangio, M., 7 May 2014, In : Frontiers in cellular neuroscience. 8, 7 p., 121.

    Research output: Contribution to journalLiterature review

  30. Monocytes expressing CX3CR1 orchestrate the development of vincristine-induced pain

    Old, E. A., Nadkarni, S., Grist, J., Gentry, C., Bevan, S., Kim, K-W., Mogg, A. J., Perretti, M. & Malcangio, M., May 2014, In : Journal of Clinical Investigation. 124, 5, p. 2023-2036 14 p.

    Research output: Contribution to journalArticle

  31. 2013
  32. ALK rearrangements in EBUS-derived transbronchial needle aspiration cytology in lung cancer

    Neat, M. J., Foot, N. J., Hicks, A., Breen, R., Wilkins, B., McLean, E. & Santis, G., Dec 2013, In : Cytopathology. 24, 6, p. 356-364 9 p.

    Research output: Contribution to journalArticle

  33. Neuropathic pain and cytokines: Current perspectives

    Clark, A. K., Old, E. A. & Malcangio, M., 20 Nov 2013, In : Journal of Pain Research. 6, p. 803-814 12 p.

    Research output: Contribution to journalArticle

  34. microRNAs in nociceptive circuits as predictors of future clinical applications

    Kress, M., Hüttenhofer, A., Landry, M., Kuner, R., Favereaux, A., Greenberg, D., Bednarik, J., Heppenstall, P., Kronenberg, F., Malcangio, M., Rittner, H., Üçeyler, N., Trajanoski, Z., Mouritzen, P., Birklein, F., Sommer, C. & Soreq, H., 17 Oct 2013, In : Frontiers in Molecular Neuroscience. 6, OCT

    Research output: Contribution to journalArticle

  35. Astrocytes-Multitaskers in chronic pain

    Hansen, R. R. & Malcangio, M., 15 Sep 2013, In : European Journal of Pharmacology. 716, 1-3, p. 120-128 9 p., N/A.

    Research output: Contribution to journalLiterature review

  36. The role of Coxsackie and adenoviral receptor in TNF alpha driven inflammation in lung epithelial cells

    Hicks, A. P., Morton, P., Parsons, M. & Santis, G., Sep 2013, In : Allergy. 68, s97, p. 224-225 2 p., 536.

    Research output: Contribution to journalPoster abstract

  37. Acquired resistance to EGFR inhibition: evolution from adenocarcinoma to small cell lung cancer (SCLC)

    Moss, C., Cane, R., Mclean, E., Santis, G., Tobal, K. & Spicer, J., Jan 2013, In : Lung Cancer. 79, Supplement 1, p. S5-S5 1 p., 13.

    Research output: Contribution to journalPoster abstract

  38. 2012
  39. Routine EGFR and KRAS Mutation analysis using COLD-PCR in non-small cell lung cancer

    Pennycuick, A., Simpson, T., Crawley, D., Lal, R., Santis, G., Cane, P., Tobal, K. & Spicer, J., Aug 2012, In : International Journal of Clinical Practice. 66, 8, p. 748-752 5 p.

    Research output: Contribution to journalArticle

  40. Spinal cathepsin S and fractalkine contribute to chronic pain in the collagen-induced arthritis model

    Clark, A. K., Grist, J., Al-Kashi, A., Perretti, M. & Malcangio, M., Jun 2012, In : Arthritis & Rheumatism. 64, 6, p. 2038-2047 10 p.

    Research output: Contribution to journalArticle

  41. Assessment and treatment of pain in people with dementia

    Corbett, A., Husebo, B., Malcangio, M., Staniland, A., Cohen-Mansfield, J., Aarsland, D. & Ballard, C., May 2012, In : Nature Reviews Neurology. 8, 5, p. 264-274 11 p., N/A.

    Research output: Contribution to journalArticle

  42. Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons

    Minett, M. S., Nassar, M. A., Clark, A. K., Passmore, G., Dickenson, A. H., Wang, F., Malcangio, M. & Wood, J. N., 24 Apr 2012, In : Nature Communications. 3, N/A, p. N/A 9 p., 791.

    Research output: Contribution to journalArticle

  43. Microglial signalling mechanisms: Cathepsin S and Fractalkine

    Clark, A. K. & Malcangio, M., Apr 2012, In : Experimental Neurology. 234, 2, p. 283 - 292 10 p.

    Research output: Contribution to journalLiterature review

  44. Chemokine mediated neuron-glia communication and aberrant signalling in neuropathic pain states

    Old, E. A. & Malcangio, M., Feb 2012, In : Current Opinion in Pharmacology. 12, 1, p. 67 - 73 7 p.

    Research output: Contribution to journalArticle

  45. The changing numbers and indications of mediastinoscopy procedures performed following the introduction of endobronchical ultrasound at a UK tertiary centre (vol 66, pg A140, 2011)

    Bakir, M., Breen, R., Quinn, A., King, J. & Santis, G., 2012, In : Thorax. 67, 2, p. 178 - 178 1 p.

    Research output: Contribution to journalArticle

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