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Research Outputs

  1. 2017
  2. Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation

    Nabeebaccus, A. A., Zoccarato, A., Hafstad, A. D., Santos, C. X., Aasum, E., Brewer, A. C., Zhang, M., Beretta, M., Yin, X., West, J. A., Schröder, K., Griffin, J. L., Eykyn, T. R., Abel, E. D., Mayr, M. & Shah, A. M., 21 Dec 2017, In : JCI Insight. 2, 24

    Research output: Contribution to journalArticle

  3. Erratum to Statistical analysis plan for the Laser-1st versus Drops-1st for Glaucoma and Ocular Hypertension Trial (LiGHT): a multi-centre randomised controlled trial

    Vickerstaff, V., Ambler, G., Bunce, C., Xing, W. & Gazzard, G., 11 Dec 2017, Trials. p. 318 1 p. (Trials; vol. 18).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  4. Fragilité cutanée et kératodermie palmoplantaire : pensez (aussi) au PLACK Syndrome: Journées Dermatologiques de Paris 2017

    Alkhalifah, A., Chiaverini, C., Del Giudice, P., Supsrisunjai, C., Hsu, C. K., Liu, L., Charlesworth, A., McGrath, J. A. & Lacour, J. P., Dec 2017, In : Annales De Dermatologie et De Venereologie. 144, 12, Supplement, p. S79-S80

    Research output: Contribution to journalMeeting abstract

  5. Recessive mutation in tetraspanin CD151 causes Kindler syndrome-like epidermolysis bullosa with multi-systemic manifestations including nephropathy

    Vahidnezhad, H., Youssefian, L., Saeidian, A. H., Mahmoudi, H., Touati, A., Abiri, M., Kajbafzadeh, A. M., Aristodemou, S., Liu, L., McGrath, J. A., Ertel, A., Londin, E., Kariminejad, A., Zeinali, S., Fortina, P. & Uitto, J., 11 Nov 2017, In : Matrix Biology.

    Research output: Contribution to journalArticle

  6. Sight Impairment registration due to stroke: A small yet significant rise?

    Bunce, C., Zekite, A., Wormald, R. & Rowe, F., 29 Oct 2017, In : Brain and Behavior. 7, 12, 5 p., e00866.

    Research output: Contribution to journalArticle

  7. Patients With Normal Tension Glaucoma Have Relative Sparing of the Relative Afferent Pupillary Defect Compared to Those With Open Angle Glaucoma and Elevated Intraocular Pressure

    Lawlor, M., Quartilho, A., Bunce, C., Nathwani, N., Dowse, E., Kamal, D. & Gazzard, G., 1 Oct 2017, In : Investigative Ophthalmology & Visual Science. 58, 12, p. 5237-5241 5 p.

    Research output: Contribution to journalArticle

  8. Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity

    Coats, B. R., Schoenfelt, K. Q., Barbosa-Lorenzi, V. C., Peris, E., Cui, C., Hoffman, A., Zhou, G., Fernandez, S., Zhai, L., Hall, B. A., Haka, A. S., Shah, A. M., Reardon, C. A., Brady, M. J., Rhodes, C. J., Maxfield, F. R. & Becker, L., 26 Sep 2017, In : Cell Reports. 20, 13, p. 3149-3161 13 p.

    Research output: Contribution to journalArticle

  9. Ab interno supraciliary microstent surgery for open angle glaucoma

    Sandhu, A., Jayaram, H., Hu, K., Bunce, C. & Gazzard, G., 20 Sep 2017, In : Cochrane Database of Systematic Reviews. 2017, 9, CD012802.

    Research output: Contribution to journalArticle

  10. Caveolin-1 controls hyperresponsiveness to mechanical stimuli and fibrogenesis-associated RUNX2 activation in keloid fibroblasts

    Hsu, C-K., Lin, H-H., Harn, H. I-C., Ogawa, R., Wang, Y-K., Ho, Y-T., Chen, W-R., Lee, Y-C., Lee, J. Y-Y., Shieh, S-J., Cheng, C-M., McGrath, J. A. & Tang, M-J., 9 Sep 2017, In : Journal of Investigative Dermatology.

    Research output: Contribution to journalArticle

  11. 227 Patient pre-selection outcomes for the European GENEGRAFT ex vivo phase I/II gene therapy trial for recessive dystrophic epidermolysis bullosa: ESDR 2017 Annual Meeting47th Annual ESDR Meeting

    Lwin, S. M., Gaucher, S., Titeux, M., Abdul-Wahab, A., Pironon, N., Miskinyte, S., GANIER, C., Duchatelet, S., McGrath, J. & Hovnanian, A., 8 Sep 2017, In : Journal of Investigative Dermatology. 137, 10, Supplement 2, p. S231

    Research output: Contribution to journalArticle

  12. 261 Tissue and circulating microRNA co-expression analysis reveals potential involvement of miRNAs in the pathobiology of frontal fibrosing alopecia: ESDR 2017 Annual Meeting47th Annual ESDR Meeting

    Tziotzios, C., Ainali, C., Onoufriadis, A., Cunningham, F., Palamaras, I., Stefanato, C. M., Kirkpatrick, N., Vano-Galvan, S., Fenton, D. A. & McGrath, J., 8 Sep 2017, In : Journal of Investigative Dermatology. 137, 10, Supplement 2, p. S237

    Research output: Contribution to journalMeeting abstract

  13. Novel homozygous missense mutation in NT5C2 underlying Hereditary Spastic Paraplegia SPG45

    Straussberg, R., Onoufriadis, A., Konen, O., Zouabi, Y., Cohen, L., Lee, J. Y. W., Hsu, C-K., Simpson, M. A. & McGrath, J. A., 8 Sep 2017, In : American Journal of Medical Genetics. Part A.

    Research output: Contribution to journalArticle

  14. Amelexanox enhances premature termination codon read-through in COL7A1 and expression of full length type VII collagen: Potential for recessive dystrophic epidermolysis bullosa

    Atanasova, V., Jiang, Q., Prisco, M., Gruber, C., Piñón Hofbauer, J., Chen, M., Has, C., Leena, B-T., McGrath, J. A., Uitto, J. & South, A. P., 1 Sep 2017, In : Journal of Investigative Dermatology. 137, 9, p. 1842-1849

    Research output: Contribution to journalArticle

  15. Ophthalmic statistics note 12: multivariable or multivariate: what's in a name?

    Bunce, C., Czanner, G., Grzeda, M. T., Doré, C. J. & Freemantle, N., 30 Aug 2017, In : The British journal of ophthalmology.

    Research output: Contribution to journalArticle

  16. Topical treatments for vernal keratoconjunctivitis

    Flynn, T., Dahlmann-Noor, A., Bunce, C. & Tuft, S., 22 Aug 2017, In : The Cochrane database of systematic reviews. 2017, 8, CD010466.

    Research output: Contribution to journalArticle

  17. Efficacy and safety of bimatoprost in glaucoma and ocular hypertension in non-responder patients

    Brennan, N., Dehabadi, M. H., Nair, S., Quartilho, A., Bunce, C., Reekie, I. & Obikpo, R., 18 Aug 2017, In : INTERNATIONAL JOURNAL OF OPHTHALMOLOGY. 10, 8, p. 1251-1254

    Research output: Contribution to journalArticle

  18. Can we reduce the burden of the current UK guidelines for retinopathy of prematurity screening?

    Adams, G. G. W., Williams, C., Modi, N., Xing, W., Bunce, C., Dahlmann-Noor, A. & UK Retinopathy of Prematurity Special Interest Group, 11 Aug 2017, In : Eye (London, England).

    Research output: Contribution to journalArticle

  19. Ab interno trabecular bypass surgery with Schlemḿs Canal Microstent (Hydrus) for open angle glaucoma

    Otarola, F., Hu, K., Gazzard, G. & Bunce, C., 3 Aug 2017, In : The Cochrane database of systematic reviews. 2017, 8, CD012740.

    Research output: Contribution to journalArticle

  20. Endoscopic cyclophotocoagulation (ECP) for open angle glaucoma and primary angle closure

    Tóth, M., Hu, K., Bunce, C. & Gazzard, G., 3 Aug 2017, In : The Cochrane database of systematic reviews. 2017, 8, CD012741.

    Research output: Contribution to journalArticle

  21. Active surveillance of choroidal neovascularisation in children: incidence, aetiology and management findings from a national study in the UK.

    Moosajee, M., Abbouda, A., Foot, B., Bunce, C., Moore, A. T. & Acheson, J., 1 Aug 2017, In : The British journal of ophthalmology.

    Research output: Contribution to journalArticle

  22. Biallelic mutations in KDSR disrupt ceramide synthesis and result in a spectrum of keratinization disorders associated with thrombocytopenia

    Takeichi, T., Torrelo, A., Lee, J. Y. W., Ohno, Y., Lozano, M. L., Kihara, A., Liu, L., Yasuda, Y., Ishikawa, J., Murase, T., Rodrigo, A. B., Fernández-Crehuet, P., Toi, Y., Mellerio, J., Rivera, J., Vicente, V., Kelsell, D. P., Nishimura, Y., Okuno, Y., Kojima, D. & 6 others, Ogawa, Y., Sugiura, K., Simpson, M. A., McLean, W. H. I., Akiyama, M. & McGrath, J. A., 31 Jul 2017, In : Journal of Investigative Dermatology. 137, 11, p. 2344-2353

    Research output: Contribution to journalArticle

  23. Tissue and circulating microRNA co-expression analysis reveals potential involvement of miRNAs in the pathobiology of frontal fibrosing alopecia

    Tziotzios, C., Ainali, C., Holmes, S., Cunningham, F., Lwin, S. M., Palamaras, I., Bhargava, K., Rymer, J., Stefanato, C., Kirkpatrick, N., Vano-Galvan, S., Petridis, C., Fenton, D. A., Simpson, M. A., Onoufriadis, A. & McGrath, J. A., 31 Jul 2017, In : Journal of Investigative Dermatology. 137, 11, p. 2440-2443

    Research output: Contribution to journalLetter

  24. Retrospective analysis of newly recorded certifications of visual impairment due to diabetic retinopathy in Wales during 2007-2015

    Thomas, R. L., Luzio, S. D., North, R. V., Banerjee, S., Zekite, A., Bunce, C. & Owens, D. R., 18 Jul 2017, In : BMJ open. 7, 7, e015024.

    Research output: Contribution to journalArticle

  25. Autoinflammatory keratinization diseases

    Akiyama, M., Takeichi, T., McGrath, J. A. & Sugiura, K., 28 Jun 2017, In : Journal of Allergy and Clinical Immunology. 3 p.

    Research output: Contribution to journalArticle

  26. Positioning In Macular hole Surgery (PIMS): Statistical analysis plan for a randomised controlled trial

    Bell, L., Hooper, R., Bunce, C., Pasu, S. & Bainbridge, J., 13 Jun 2017, In : Trials. 18, 1, 274.

    Research output: Contribution to journalArticle

  27. PLACK syndrome resulting from a new homozygous insertion mutation in CAST

    Alkhalifah, A., Chiaverini, C., Del Giudice, P., Supsrisunjai, C., Hsu, C-K., Liu, L., Charlesworth, A., McGrath, J. A. & Lacour, J-P., 9 Jun 2017, In : Journal of Dermatological Science.

    Research output: Contribution to journalArticle

  28. Dual requirements for WNT10A in proliferation and KLF4-mediated differentiation underlie ectodermal dysplasia

    Zu, M., Horrell, J., Snitow, M., Cui, J., Gochnauer, H., Syrett, C. M., Kallish, S., Seykora, J. T., Liu, F., Gaillard, D., Katz, J. P., Kaestner, K. H., Levin, B., Mansfield, C., Douglas, J. E., Cowart, B. J., Tordoff, M., Liu, F., Zhu, X., Barlow, L. A. & 5 others, Rubin, A. I., McGrath, J. A., Morrisey, E. E., Chu, E. Y. & Millar, S. E., 7 Jun 2017, In : Nature Communications. 8

    Research output: Contribution to journalArticle

  29. A new clinical diagnostic matrix for epidermolysis bullosa

    McGrath, J. A., 5 Jun 2017, In : British Journal of Dermatology. 176, 6, p. 1442–1443 2 p.

    Research output: Contribution to journalArticle

  30. Tablet computers versus optical AIDS to support education and learning in children and young people with low vision: Protocol for a pilot randomised controlled trial, CREATE (Children Reading with Electronic Assistance to Educate)

    Crossland, M. D., Thomas, R., Unwin, H., Bharani, S., Gothwal, V. K., Quartilho, A., Bunce, C. & Dahlmann-Noor, A., 1 Jun 2017, In : BMJ Open. 7, 6, e015939.

    Research output: Contribution to journalArticle

  31. Decoding NADPH Oxidase 4 Expression in Human Tumors

    Meitzler, J. L., Makhlouf, H. R., Antony, S., Wu, Y., Butcher, D., Jiang, G., Juhasz, A., Lu, J., Dahan, I., Jansen-Dürr, P., Pircher, H., Shah, A. M., Roy, K. & Doroshow, J. H., 26 May 2017, In : Redox Biology. 13, p. 182–195

    Research output: Contribution to journalArticle

  32. Ranibizumab pretreatment in diabetic vitrectomy: a pilot randomised controlled trial (the RaDiVit study)

    Comyn, O., Wickham, L., Charteris, D. G., Sullivan, P. M., Ezra, E., Gregor, Z., Aylward, G. W., da Cruz, L., Fabinyi, D., Peto, T., Restori, M., Xing, W., Bunce, C., Hykin, P. G. & Bainbridge, J. W., 12 May 2017, In : Eye (London, England). 31, p. 1253–1258 8 p.

    Research output: Contribution to journalArticle

  33. Structure and function of skin, hair and nails

    Lai-Cheong, J. E. & McGrath, J. A., 5 May 2017, In : Medicine.

    Research output: Contribution to journalArticle

  34. Blood Pressure in Healthy Humans is Regulated by Neuronal NO Synthase

    Shabeeh, H., Khan, S., Jiang, B., Brett, S., Melikian, N., Casadei, B., Chowienczyk, P. J. & Shah, A. M., 1 May 2017, In : Hypertension. 69, 5, p. 970-976 7 p.

    Research output: Contribution to journalArticle

  35. Congenital Anonychia and Uncombable Hair Syndrome: Coinheritance of Homozygous Mutations in RSPO4 and PADI3

    Hsu, C. K., Romano, M. T., Nanda, A., Rashidghamat, E., Lee, J. Y. W., Huang, H. Y., Songsantiphap, C., Lee, J. Y. Y., Al-Ajmi, H., Betz, R. C., Simpson, M. A., McGrath, J. A. & Tziotzios, C., 1 May 2017, In : Journal of Investigative Dermatology. 137, 5, p. 1176-1179 4 p.

    Research output: Contribution to journalArticle

  36. 515 Mutations in KLHL24 add to the molecular heterogeneity of epidermolysis bullosa simplex: SID 2017 Annual Meeting Abstract SupplementSociety for Investigative Dermatology Annual Meeting

    Lee, J. Y. W., Liu, L., Hsu, C., Aristodemou, S., Ozoemena, L., Ogboli, M., Moss, C., Martinez, A. E., Mellerio, J. E. & McGrath, J., May 2017, In : Journal of Investigative Dermatology. 137, 5, Supplement 1, p. S88

    Research output: Contribution to journalMeeting abstract

  37. Quality of Life and Functional Vision in Children with Glaucoma

    Dahlmann-Noor, A., Tailor, V., Bunce, C., Abou-Rayyah, Y., Adams, G., Brookes, J., Khaw, P. T. & Papadopoulos, M., 3 Apr 2017, In : Ophthalmology.

    Research output: Contribution to journalArticle

  38. Distinct Regulatory Effects of Myeloid Cell and Endothelial Cell Nox2 on Blood Pressure

    Sag, C. M., Schnelle, M., Zhang, J., Murdoch, C. E., Kossmann, S., Protti, A., Santos, C. X. C., Sawyer, G. J., Zhang, X., Mongue-Din, H., Richards, D. A., Brewer, A. C., Prysyazhna, O., Maier, L. S., Wenzel, P., Eaton, P. J. & Shah, A. M., 28 Mar 2017, In : Circulation (Baltimore).

    Research output: Contribution to journalArticle

  39. ECHOCARDIOGRAPHIC ESTIMATION OF MEAN PULMONARY ARTERY PRESSURE: A COMPARISON OF DIFFERENT APPROACHES TO PREDICT PULMONARY HYPERTENSION

    Seidler, T., Hellenkamp, K., Unsöld, B., Mushemi-Blake, S., Shah, A. & Hasenfuss, G., 21 Mar 2017, In : Journal of the American College of Cardiology. 69, 11, Supplement, p. 1889 1 p.

    Research output: Contribution to journalArticle

  40. Treatment trends for retinopathy of prematurity in the UK: active surveillance study of infants at risk

    Adams, G. G. W., Bunce, C., Xing, W., Butler, L., Long, V., Reddy, A. & Dahlmann-Noor, A. H., 21 Mar 2017, In : BMJ open. 7, 3, p. e013366

    Research output: Contribution to journalArticle

  41. Mutations in AAGAB underlie autosomal dominant punctate palmoplantar keratoderma

    Dinani, N., Ali, M., Liu, L., McGrath, J. & Mellerio, J., 16 Mar 2017, In : Clinical and Experimental Dermatology. 42, 3, p. 316-319 4 p.

    Research output: Contribution to journalArticle

  42. Is artificial reproductive technology a risk factor for retinopathy of prematurity independent of the generation of multiple births?

    Barker, L., Bunce, C., Husain, S. & Adams, G. G. W., 10 Mar 2017, In : European Journal of Ophthalmology. p. 174-178

    Research output: Contribution to journalArticle

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