King's College London

Research portal

Research Outputs

  1. 2017
  2. Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation

    Nabeebaccus, A. A., Zoccarato, A., Hafstad, A. D., Santos, C. X., Aasum, E., Brewer, A. C., Zhang, M., Beretta, M., Yin, X., West, J. A., Schröder, K., Griffin, J. L., Eykyn, T. R., Abel, E. D., Mayr, M. & Shah, A. M., 21 Dec 2017, In : JCI Insight. 2, 24

    Research output: Contribution to journalArticle

  3. Refinement of a Methodology for Untargeted Detection of Serum Albumin Adducts in Human Populations

    Preston, G. W., Plusquin, M., Sozeri, O., Van Veldhoven, K., Bastian, L., Nawrot, T. S., Chadeau-Hyam, M. & Phillips, D. H., 18 Dec 2017, In : Chemical Research in Toxicology. 30, 12, p. 2120-2129

    Research output: Contribution to journalArticle

  4. Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity

    Coats, B. R., Schoenfelt, K. Q., Barbosa-Lorenzi, V. C., Peris, E., Cui, C., Hoffman, A., Zhou, G., Fernandez, S., Zhai, L., Hall, B. A., Haka, A. S., Shah, A. M., Reardon, C. A., Brady, M. J., Rhodes, C. J., Maxfield, F. R. & Becker, L., 26 Sep 2017, In : Cell Reports. 20, 13, p. 3149-3161 13 p.

    Research output: Contribution to journalArticle

  5. Decoding NADPH Oxidase 4 Expression in Human Tumors

    Meitzler, J. L., Makhlouf, H. R., Antony, S., Wu, Y., Butcher, D., Jiang, G., Juhasz, A., Lu, J., Dahan, I., Jansen-Dürr, P., Pircher, H., Shah, A. M., Roy, K. & Doroshow, J. H., 26 May 2017, In : Redox Biology. 13, p. 182–195

    Research output: Contribution to journalArticle

  6. Blood Pressure in Healthy Humans is Regulated by Neuronal NO Synthase

    Shabeeh, H., Khan, S., Jiang, B., Brett, S., Melikian, N., Casadei, B., Chowienczyk, P. J. & Shah, A. M., 1 May 2017, In : Hypertension. 69, 5, p. 970-976 7 p.

    Research output: Contribution to journalArticle

  7. Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone

    Arlt, V. M., Meinl, W., Florian, S., Nagy, E., Barta, F., Thomann, M., Mrizova, I., Krais, A. M., Liu, M., Richards, M., Mirza, A., Kopka, K., Phillips, D. H., Glatt, H., Stiborova, M. & Schmeiser, H. H., Apr 2017, In : Archives of Toxicology. 91, 4, p. 1957-1975

    Research output: Contribution to journalArticle

  8. Distinct Regulatory Effects of Myeloid Cell and Endothelial Cell Nox2 on Blood Pressure

    Sag, C. M., Schnelle, M., Zhang, J., Murdoch, C. E., Kossmann, S., Protti, A., Santos, C. X. C., Sawyer, G. J., Zhang, X., Mongue-Din, H., Richards, D. A., Brewer, A. C., Prysyazhna, O., Maier, L. S., Wenzel, P., Eaton, P. J. & Shah, A. M., 28 Mar 2017, In : Circulation (Baltimore).

    Research output: Contribution to journalArticle

  9. ECHOCARDIOGRAPHIC ESTIMATION OF MEAN PULMONARY ARTERY PRESSURE: A COMPARISON OF DIFFERENT APPROACHES TO PREDICT PULMONARY HYPERTENSION

    Seidler, T., Hellenkamp, K., Unsöld, B., Mushemi-Blake, S., Shah, A. & Hasenfuss, G., 21 Mar 2017, In : Journal of the American College of Cardiology. 69, 11, Supplement, p. 1889 1 p.

    Research output: Contribution to journalArticle

  10. Selective Enhancement of Insulin Sensitivity in the Endothelium in Vivo Reveals a Novel Proatherosclerotic Signaling Loop

    Viswambharan, H., Yuldasheva, N. Y., Sengupta, A., Imrie, H., Gage, M. C., Haywood, N., Walker, A. M. N., Skromna, A., Makova, N., Galloway, S., Shah, P., Sukumar, P., Porter, K. E., Grant, P. J., Shah, A., Santos, C. X., Li, J., Beech, D. J., Wheatcroft, S. B., Cubbon, R. M. & 1 others, Kearney, M. T., 3 Mar 2017, In : Circulation Research. 120, 5, p. 784-798 15 p.

    Research output: Contribution to journalArticle

  11. Nutlin-3a selects for cells harbouring TP53 mutations

    Kucab, J. E., Hollstein, M., Arlt, V. M. & Phillips, D. H., 15 Feb 2017, In : International Journal of Cancer. 140, 4, p. 877-887 11 p.

    Research output: Contribution to journalArticle

  12. Hypoxia induces heart regeneration in adult mice

    Nakada, Y., Canseco, D. C., Thet, S., Abdisalaam, S., Asaithamby, A., Xavier Da Costa Dos Santos, C. S., Shah, A. M., Zhang, H., Faber, J. E., Kinter, M. T., Szweda, L. I., Xing, C., Hu, Z., Deberardinis, R. J., Schiattarella, G., Hill, J. A., Oz, O., Lu, Z., Zhang, C. C., Kimura, W. & 1 others, Sadek, H. A., 12 Jan 2017, In : NATURE. 541, 7636, p. 222-227 6 p.

    Research output: Contribution to journalArticle

  13. PHD2 is a regulator for glycolytic reprogramming in macrophages

    Guentsch, A., Beneke, A., Swain, L., Farhat, K., Nagarajan, S., Wielockx, B., Raithatha, K., Dudek, J., Rehling, P., Zieseniss, A., Jatho, A., Chong, M., Santos, C. X. C., Shah, A. M. & Katschinski, D. M., Jan 2017, In : Molecular and Cellular Biology. 37, 1, e00236-16.

    Research output: Contribution to journalArticle

  14. 2016
  15. From the exposome to mechanistic understanding of chemical-induced adverse effects

    Escher, B. I., Hackermüller, J., Polte, T., Scholz, S., Aigner, A., Altenburger, R., Böhme, A., Bopp, S. K., Brack, W., Busch, W., Chadeau-Hyam, M., Covaci, A., Eisenträger, A., Galligan, J. J., Garcia-Reyero, N., Hartung, T., Hein, M., Herberth, G., Jahnke, A., Kleinjans, J. & 16 others, Klüver, N., Krauss, M., Lamoree, M., Lehmann, I., Luckenbach, T., Miller, G. W., Müller, A., Phillips, D. H., Reemtsma, T., Rolle-Kampczyk, U., Schüürmann, G., Schwikowski, B., Tan, Y-M., Trump, S., Walter-Rohde, S. & Wambaugh, J. F., 8 Dec 2016, In : Environment International.

    Research output: Contribution to journalArticle

  16. Toll-like receptor 9 prevents cardiac rupture after myocardial infarction in mice independently of inflammation

    Omiya, S., Omori, Y., Taneike, M., Protti, A., Yamaguchi, O., Akira, S., Shah, A., Nishida, K. & Otsu, K., Dec 2016, In : American Journal of Physiology (Heart and Circulatory Physiology). 311, 6, p. H1485-H1497

    Research output: Contribution to journalArticle

  17. Mutational signatures associated with tobacco smoking in human cancer

    Alexandrov, L. B., Ju, Y. S., Haase, K., Van Loo, P., Martincorena, I., Nik-Zainal, S., Totoki, Y., Fujimoto, A., Nakagawa, H., Shibata, T., Campbell, P. J., Vineis, P., Phillips, D. H. & Stratton, M. R., 4 Nov 2016, In : Science. 354, 6312, p. 618-622 5 p.

    Research output: Contribution to journalArticle

  18. Redox Imaging Using Cardiac Myocyte-Specific Transgenic Biosensor Mice

    Swain, L., Kesemeyer, A., Meyer-Roxlau, S., Vettel, C., Zieseniss, A., Güntsch, A., Jatho, A., Becker, A., Nanadikar, M. S., Morgan, B., Dennerlein, S., Shah, A., El-Armouche, A., Nikolaev, V. O. & Katschinski, D. M., 14 Oct 2016, In : Circulation Research. 119, 9, p. 1004-1016 13 p.

    Research output: Contribution to journalArticle

  19. Apocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state

    Trevelin, S. C., Dos Santos, C. X., Ferreira, R. G., de Sá Lima, L., Silva, R. L., Scavone, C., Curi, R., Alves-Filho, J. C., Cunha, T. M., Roxo-Júnior, P., Cervi, M-C., Laurindo, F. R. M., Hothersall, J. S., Cobb, A. M., Zhang, M., Ivetic, A., Shah, A. M., Lopes, L. R. & Cunha, F. Q., 4 Oct 2016, In : Scientific Reports. 6, 34581.

    Research output: Contribution to journalArticle

  20. CRISPR/Cas9-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity

    Prior, K-K., Leisegang, M. S., Josipovic, I., Löwe, O., Shah, A. M., Weissmann, N., Schröder, K. & Brandes, R. P., Oct 2016, In : Redox Biology. 9, p. 287–295

    Research output: Contribution to journalArticle

  21. Glycoproteomics Reveals Decorin Peptides with Anti-Myostatin Activity in Human Atrial Fibrillation

    Barallobre-Barreiro, J., Gupta, S. K., Zoccarato, A., Kitazume-Taneike, R., Fava, M., Yin, X., Werner, T., Hirt, M. N., Zampetaki, A., Viviano, A., Chong, M., Bern, M., Kourliouros, A., Domenech, N., Willeit, P., Shah, A. M., Jahangiri, M., Schaefer, L., Fischer, J. W., Iozzo, R. V. & 6 others, Viner, R., Thum, T., Heineke, J., Kichler, A., Otsu, K. & Mayr, M., 13 Sep 2016, In : Circulation (Baltimore). 134, 11, p. 817-832 16 p.

    Research output: Contribution to journalArticle

  22. Magnetic Drug Targeting: Preclinical in Vivo Studies, Mathematical Modeling, and Extrapolation to Humans

    Al-Jamal, K. T., Bai, J., Tzu-Wen Wang, J., Protti, A., Southern, P., Bogart, L., Heidari, H., Li, X., Cakebread, A., Asker, D., Al-Jamal, W. T., Shah, A., Bals, S., Sosabowski, J. & Pankhurst, Q. A., 19 Aug 2016, In : Nano Letters. 16, 9, p. 5652-5660

    Research output: Contribution to journalLetter

  23. NADH:Cytochrome b5 reductase and cytochrome b5 can act as sole electron donors to human cytochrome P450 1A1-mediated oxidation and DNA adduct formation by benzo[a]pyrene

    Stiborova, M., Indra, R., Moserova, M., Frei, E., Schmeiser, H. H., Kopka, K., Phillips, D. H. & Arlt, V. M., 15 Aug 2016, In : Chemical Research in Toxicology. 29, 8, p. 1325-1334

    Research output: Contribution to journalArticle

  24. Molecular mechanisms linking autonomic dysfunction and impaired cardiac contractility in critical illness

    Ackland, G. L., Whittle, J., Toner, A., Machhada, A., Del Arroyo, A. G., Sciuso, A., Jenkins, N., Dyson, A., Struthers, R., Sneyd, J. R., Minto, G., Singer, M., Shah, A. & Gourine, A. V., 1 Aug 2016, In : Critical Care Medicine. 44, 8, p. e614-e624

    Research output: Contribution to journalArticle

  25. Potential Effect of Brexit on Cardiovascular Translational Science

    Shah, A. M. & Mann, D. L., 1 Aug 2016, In : JACC: Basic to Translational Science. 1, 5, p. 416-417 2 p.

    Research output: Contribution to journalArticle

  26. Heart failure-potential new targets for therapy

    Nabeebaccus, A., Zheng, S. & Shah, A. M., 30 Jun 2016, In : British Medical Bulletin. 119, 1, p. 99-110

    Research output: Contribution to journalArticle

  27. Transcriptional profiling of the mouse hippocampus supports an NMDAR-mediated neurotoxic mode of action for benzo[a]pyrene

    Chepelev, N. L., Long, A. S., Bowers, W. J., Gagné, R., Williams, A., Kuo, B., Phillips, D. H., Arlt, V. M., White, P. A. & Yauk, C. L., Jun 2016, In : Environmental and Molecular Mutagenesis. 57, 5, p. 350–363

    Research output: Contribution to journalArticle

  28. The Shortening of MWNT-SPION Hybrids by Steam Treatment Improves Their Magnetic Resonance Imaging Properties In Vitro and In Vivo

    Cabana, L., Bourgognon, M., Wang, J. T. -W., Protti, A., Klippstein, R., de Rosales, R. T. M., Shah, A. M., Fontcuberta, J., Tobías-Rossell, E., Sosabowski, J. K., Al-Jamal, K. T. & Tobias, G., 15 Apr 2016, In : Small.

    Research output: Contribution to journalArticle

  29. The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice

    Krais, A. M., Speksnijder, E. N., Melis, J. P. M., Indra, R., Moserova, M., Godschalk, R. W., van Schooten, F-J., Seidel, A., Kopka, K., Schmeiser, H. H., Stiborova, M., Phillips, D. H., Luijten, M. & Arlt, V. M., Apr 2016, In : Archives of Toxicology. 90, 4, p. 839-851 13 p.

    Research output: Contribution to journalArticle

  30. The endoplasmic reticulum chaperone calnexin is a NADPH oxidase NOX4 interacting protein

    Prior, K. K., Wittig, I., Leisegang, M. S., Groenendyk, J., Weissmann, N., Michalak, M., Jansen-Dürr, P., Shah, A. M. & Brandes, R. P., 25 Mar 2016, In : Journal of Biological Chemistry. 291, 13, p. 7045-7059 15 p.

    Research output: Contribution to journalArticle

  31. Redox Signaling In The Cardiomyocyte: From Physiology To Failure

    Santos, C. XC., Raza, S., Shah, A. M. & [Unknown], FM., 14 Mar 2016, In : International Journal of Biochemistry and Cell Biology.

    Research output: Contribution to journalArticle

  32. Mutual regulation of epicardial adipose tissue and myocardial redox state by PPAR-γ/adiponectin signalling

    Antonopoulos, A. S., Margaritis, M., Verheule, S., Recalde, A., Sanna, F., Herdman, L., Psarros, C., Nasrallah, H., Coutinho, P., Akoumianakis, I., Brewer, A. C., Sayeed, R., Krasopoulos, G., Petrou, M., Tarun, A., Tousoulis, D., Shah, A. M., Casadei, B., Channon, K. M. & Antoniades, C., 4 Mar 2016, In : Circulation Research. 118, 5, p. 842-855 14 p.

    Research output: Contribution to journalArticle

  33. Metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and DNA adduct formation depends on p53: studies in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice

    Krais, A. M., Speksnijder, E. N., Melis, J. P. M., Singh, R., Caldwell, A., Gamboa da Costa, G., Luijten, M., Phillips, D. H. & Arlt, V. M., 15 Feb 2016, In : International Journal of Cancer. 138, 4, p. 976–982

    Research output: Contribution to journalArticle

  34. Ambulatory heart rate range predicts mode-specific mortality and hospitalisation in chronic heart failure

    Cubbon, R. M., Ruff, N., Groves, D., Eleuteri, A., Denby, C., Kearney, L., Ali, N., Walker, A. M. N., Jamil, H., Gierula, J., Gale, C. P., Batin, P. D., Nolan, J., Shah, A. M., Fox, K. A. A., Sapsford, R. J., Witte, K. K. & Kearney, M. T., 1 Feb 2016, In : Heart. 102, 3, p. 223-229 7 p.

    Research output: Contribution to journalArticle

  35. Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism

    Wohak, L., Krais, A. M., Kucab, J. E., Stertmann, J., Ovrebø, S., Seidel, A., Phillips, D. H. & Arlt, V. M., 1 Feb 2016, In : Archives of Toxicology. 90, 2, p. 291-304 14 p.

    Research output: Contribution to journalArticle

  36. NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells

    Jayavelu, A. K., Müller, J. P., Bauer, R., Böhmer, S. A., Lässig, J., Cerny-Reiterer, S., Sperr, W. R., Valent, P., Maurer, B., Moriggl, R., Schröder, K., Shah, A. M., Fischer, M., Scholl, S., Barth, J., Oellerich, T., Berg, T., Serve, H., Frey, S., Fischer, T. & 2 others, Heidel, F. H. & Böhmer, F. D., 1 Feb 2016, In : Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 30, 2, p. 473-483 11 p.

    Research output: Contribution to journalArticle

  37. Transcriptional regulation of cystathionine-γ-lyase in endothelial cells by NADPH oxidase 4-dependent signaling

    Mistry, R. K., Murray, T. V. A., Prysyazhna, O., Martin, D., Burgoyne, J., Santos, C., Eaton, P., Shah, A. M. & Brewer, A. C., 22 Jan 2016, In : Journal of Biological Chemistry. 291, 4, p. 1774-1788 15 p.

    Research output: Contribution to journalArticle

  38. Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α-mediated stress signaling

    Santos, C. X., Hafstad, A. D., Beretta, M., Zhang, M., Molenaar, C., Kopec, J., Fotinou, D., Murray, T. V., Cobb, A. M., Martin, D., Zeh Silva, M., Anilkumar, N., Schröder, K., Shanahan, C. M., Brewer, A. C., Brandes, R. P., Blanc, E., Parsons, M., Belousov, V., Cammack, R. & 3 others, Hider, R. C., Steiner, R. A. & Shah, A. M., 18 Jan 2016, In : The EMBO journal. 35, 2, p. 115-236

    Research output: Contribution to journalArticle

  39. Transcriptional profiling of dibenzo[def, p]chrysene-induced spleen atrophy provides mechanistic insights into its immunotoxicity in mutamouse

    Chepelev, N. L., Long, A. S., Williams, A., Kuo, B., Gagné, R., Kennedy, D. A., Phillips, D. H., Arlt, V. M., White, P. A. & Yauk, C. L., 1 Jan 2016, In : Toxicological Sciences. 149, 1, p. 251-268 18 p.

    Research output: Contribution to journalArticle

Previous 1 2 3 4 5 6 7 8 ...16 Next

Export:RIS BibTex Word PDF - will at most contain 500 items

Refine results Clear filters

Language

Language

Publication year

Full text

Full text

Meeting and poster abstracts

Authors

© 2018 King's College London | Strand | London WC2R 2LS | England | United Kingdom | Tel +44 (0)20 7836 5454