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Research Outputs

  1. 2017
  2. ECHOCARDIOGRAPHIC ESTIMATION OF MEAN PULMONARY ARTERY PRESSURE: A COMPARISON OF DIFFERENT APPROACHES TO PREDICT PULMONARY HYPERTENSION

    Seidler, T., Hellenkamp, K., Unsöld, B., Mushemi-Blake, S., Shah, A. & Hasenfuss, G., 21 Mar 2017, In : Journal of the American College of Cardiology. 69, 11, Supplement, p. 1889 1 p.

    Research output: Contribution to journalArticle

  3. Selective Enhancement of Insulin Sensitivity in the Endothelium in Vivo Reveals a Novel Proatherosclerotic Signaling Loop

    Viswambharan, H., Yuldasheva, N. Y., Sengupta, A., Imrie, H., Gage, M. C., Haywood, N., Walker, A. M. N., Skromna, A., Makova, N., Galloway, S., Shah, P., Sukumar, P., Porter, K. E., Grant, P. J., Shah, A., Santos, C. X., Li, J., Beech, D. J., Wheatcroft, S. B., Cubbon, R. M. & 1 others, Kearney, M. T., 3 Mar 2017, In : Circulation Research. 120, 5, p. 784-798 15 p.

    Research output: Contribution to journalArticle

  4. Hypoxia induces heart regeneration in adult mice

    Nakada, Y., Canseco, D. C., Thet, S., Abdisalaam, S., Asaithamby, A., Xavier Da Costa Dos Santos, C. S., Shah, A. M., Zhang, H., Faber, J. E., Kinter, M. T., Szweda, L. I., Xing, C., Hu, Z., Deberardinis, R. J., Schiattarella, G., Hill, J. A., Oz, O., Lu, Z., Zhang, C. C., Kimura, W. & 1 others, Sadek, H. A., 12 Jan 2017, In : NATURE. 541, 7636, p. 222-227 6 p.

    Research output: Contribution to journalArticle

  5. 2016
  6. Toll-like receptor 9 prevents cardiac rupture after myocardial infarction in mice independently of inflammation

    Omiya, S., Omori, Y., Taneike, M., Protti, A., Yamaguchi, O., Akira, S., Shah, A., Nishida, K. & Otsu, K., Dec 2016, In : American Journal of Physiology (Heart and Circulatory Physiology). 311, 6, p. H1485-H1497

    Research output: Contribution to journalArticle

  7. Redox Imaging Using Cardiac Myocyte-Specific Transgenic Biosensor Mice

    Swain, L., Kesemeyer, A., Meyer-Roxlau, S., Vettel, C., Zieseniss, A., Güntsch, A., Jatho, A., Becker, A., Nanadikar, M. S., Morgan, B., Dennerlein, S., Shah, A., El-Armouche, A., Nikolaev, V. O. & Katschinski, D. M., 14 Oct 2016, In : Circulation Research. 119, 9, p. 1004-1016 13 p.

    Research output: Contribution to journalArticle

  8. Apocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state

    Trevelin, S. C., Dos Santos, C. X., Ferreira, R. G., de Sá Lima, L., Silva, R. L., Scavone, C., Curi, R., Alves-Filho, J. C., Cunha, T. M., Roxo-Júnior, P., Cervi, M-C., Laurindo, F. R. M., Hothersall, J. S., Cobb, A. M., Zhang, M., Ivetic, A., Shah, A. M., Lopes, L. R. & Cunha, F. Q., 4 Oct 2016, In : Scientific Reports. 6, 34581.

    Research output: Contribution to journalArticle

  9. Molecular mechanisms linking autonomic dysfunction and impaired cardiac contractility in critical illness

    Ackland, G. L., Whittle, J., Toner, A., Machhada, A., Del Arroyo, A. G., Sciuso, A., Jenkins, N., Dyson, A., Struthers, R., Sneyd, J. R., Minto, G., Singer, M., Shah, A. & Gourine, A. V., 1 Aug 2016, In : Critical Care Medicine. 44, 8, p. e614-e624

    Research output: Contribution to journalArticle

  10. Heart failure-potential new targets for therapy

    Nabeebaccus, A., Zheng, S. & Shah, A. M., 30 Jun 2016, In : British Medical Bulletin. 119, 1, p. 99-110

    Research output: Contribution to journalArticle

  11. NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells

    Jayavelu, A. K., Müller, J. P., Bauer, R., Böhmer, S. A., Lässig, J., Cerny-Reiterer, S., Sperr, W. R., Valent, P., Maurer, B., Moriggl, R., Schröder, K., Shah, A. M., Fischer, M., Scholl, S., Barth, J., Oellerich, T., Berg, T., Serve, H., Frey, S., Fischer, T. & 2 others, Heidel, F. H. & Böhmer, F. D., 1 Feb 2016, In : Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 30, 2, p. 473-483 11 p.

    Research output: Contribution to journalArticle

  12. 2015
  13. The NADPH oxidase Nox4 has anti-atherosclerotic functions

    Schürmann, C., Rezende, F., Kruse, C., Yasar, Y., Löwe, O., Fork, C., Van De Sluis, B., Bremer, R., Weissmann, N., Shah, A. M., Jo, H., Brandes, R. P. & Schröder, K., 21 Dec 2015, In : European Heart Journal. 36, 48, p. 3447-3456 10 p.

    Research output: Contribution to journalArticle

  14. NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice

    Murray, T. V. A., Dong, X., Sawyer, G. J., Caldwell, A., Halket, J., Sherwood, R., Quaglia, A., Dew, T., Anilkumar, N., Burr, S., Mistry, R. K., Martin, D., Schröder, K., Brandes, R. P., Hughes, R. D., Shah, A. M. & Brewer, A. C., 1 Dec 2015, In : Free Radical Biology and Medicine. 89, p. 918-930 13 p.

    Research output: Contribution to journalArticle

  15. Cardiac-targeted NADPH oxidase 4 in the adaptive cardiac remodelling of the murine heart

    Nabeebaccus, A., Hafstad, A., Eykyn, T., Yin, X., Brewer, A., Zhang, M., Mayr, M. & Shah, A., 26 Feb 2015, In : Lancet. 385 Suppl 1, p. S73

    Research output: Contribution to journalArticle

  16. Heart failure: Mitochondrial dysfunction and oxidative stress in CHF

    Okonko, D. O. & Shah, A. M., 11 Jan 2015, In : Nature Reviews Cardiology. 12, 1, p. 6-8 3 p.

    Research output: Contribution to journalArticle

  17. Parsing the role of NADPH oxidase enzymes and reactive oxygen species in heart failure

    Shah, A. M., 2015, In : Circulation (Baltimore). 131, 7, p. 602-604 3 p.

    Research output: Contribution to journalArticle

  18. 2014
  19. Menthol inhibits detrusor contractility independently of TRPM8 Activation

    Ramos-Filho, A. C. S., Shah, A., Augusto, T. M., Barbosa, G. O., Leiria, L. O., De Carvalho, H. F., Antunes, E. & Grant, A. D., 6 Nov 2014, In : PL o S One . 9, 11, e111616.

    Research output: Contribution to journalArticle

  20. NADPH oxidase 2 mediates angiotensin II-dependent cellular arrhythmias via PKA and CaMKII

    Wagner, S., Dantz, C., Flebbe, H., Azizian, A., Sag, C. M., Engels, S., Möllencamp, J., Dybkova, N., Islam, T., Shah, A. M. & Maier, L. S., 1 Oct 2014, In : Journal of Molecular and Cellular Cardiology. 75, p. 206-215 10 p.

    Research output: Contribution to journalArticle

  21. Preface for redox signalling in the cardiovascular system

    Eaton, P. & Shah, A. M., Aug 2014, In : Journal of Molecular and Cellular Cardiology. 73, p. 1-1 1 p.

    Research output: Contribution to journalEditorial

  22. Redox regulation of cardiac hypertrophy

    Sag, C. M., Santos, C. X. C. & Shah, A. M., Aug 2014, In : Journal of Molecular and Cellular Cardiology. 73, p. 103-111 9 p.

    Research output: Contribution to journalLiterature review

  23. The imbalanced redox status in senescent endothelial cells is due to dysregulated Thioredoxin-1 and NADPH oxidase 4

    Goy, C., Czypiorski, P., Altschmied, J., Jakob, S., Rabanter, L. L., Brewer, A. C., Ale-Agha, N., Dyballa-Rukes, N., Shah, A. M. & Haendeler, J., Aug 2014, In : Experimental Gerontology. 56, p. 45-52 8 p.

    Research output: Contribution to journalArticle

  24. Erratum: The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response (Cell (2014) 157 (741-743))

    Puente, B. N., Kimura, W., Muralidhar, S. A., Moon, J., Amatruda, J. F., Phelps, K. L., Grinsfelder, D., Rothermel, B. A., Chen, R., Garcia, J. A., Santos, C. X., Thet, S., Mori, E., Kinter, M. T., Rindler, P. M., Zacchigna, S., Mukherjee, S., Chen, D. J., Mahmoud, A. I., Giacca, M. & 5 others, Rabinovitch, P. S., Asaithamby, A., Shah, A. M., Szweda, L. I. & Sadek, H. A., 22 May 2014, In : Cell. 157, 5, 1 p.

    Research output: Contribution to journalComment/debate

  25. ROS signalling between endothelial cells and cardiac cells

    Zhang, M. & Shah, A. M., 1 May 2014, In : Cardiovascular Research. 102, 2, p. 249-257 9 p.

    Research output: Contribution to journalLiterature review

  26. An Ongoing Role of alpha-Calcitonin Gene-Related Peptide as Part of a Protective Network Against Hypertension, Vascular Hypertrophy, and Oxidative Stress

    Smillie, S-J., King, R., Kodji, X., Outzen, E., Pozsgai, G., Fernandes, E., Marshall, N., de Winter, P., Heads, R. J., Dessapt-Baradez, C., Gnudi, L., Sams, A., Shah, A. M., Siow, R. C. & Brain, S. D., May 2014, In : Hypertension. 63, 5, p. 1056-1062 7 p.

    Research output: Contribution to journalArticle

  27. EURObservational Research Programme: a worldwide registry on peripartum cardiomyopathy (PPCM) in conjunction with the Heart Failure Association of the European Society of Cardiology Working Group on PPCM

    Sliwa, K., Hilfiker-Kleiner, D., Mebazaa, A., Petrie, M. C., Maggioni, A. P., Regitz-Zagrosek, V., Schaufelberger, M., Tavazzi, L., van Veldhuisen, D. J., Roos-Hesslink, J. W., Shah, A. J., Seferovic, P. M., Elkayam, U., van Spaendonck-Zwarts, K., Bachelier-Walenta, K., Mouquet, F., Kraigher-Krainer, E., Hall, R., Ponikowski, P., McMurray, J. J. V. & 1 others, Pieske, B., May 2014, In : EUROPEAN JOURNAL OF HEART FAILURE. 16, 5, p. 583-591 9 p.

    Research output: Contribution to journalArticle

  28. The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage Response

    Puente, B. N., Kimura, W., Muralidhar, S. A., Moon, J., Amatruda, J. F., Phelps, K. L., Grinsfelder, D., Rothermel, B. A., Chen, R., Garcia, J. A., Santos, C. X., Thet, S., Mori, E., Kinter, M. T., Rindler, P. M., Zacchigna, S., Mukherjee, S., Chen, D. J., Mahmoud, A. I., Giacca, M. & 5 others, Rabinovitch, P. S., Aroumougame, A., Shah, A. M., Szweda, L. I. & Sadek, H. A., 24 Apr 2014, In : Cell. 157, 3, p. 565-579 15 p.

    Research output: Contribution to journalArticle

  29. Peroxidasin-like protein: a novel peroxidase homologue in the human heart

    Peterfi, Z., Toth, Z. E., Kovacs, H. A., Lazar, E., Sum, A., Donko, A., Sirokmany, G., Shah, A. M. & Geiszt, M., 1 Mar 2014, In : Cardiovascular Research. 101, 3, p. 393-399 7 p., N/A.

    Research output: Contribution to journalArticle

  30. Endoplasmic Reticulum Stress and Nox-Mediated Reactive Oxygen Species Signaling in the Peripheral Vasculature: Potential Role in Hypertension

    Santos, C. X. C., Nabeebaccus, A. A., Shah, A. M., Camargo, L. L., Filho, S. V. & Lopes, L. R., 1 Jan 2014, In : ANTIOXIDANTS AND REDOX SIGNALING. 20, 1, p. 121-134 14 p.

    Research output: Contribution to journalLiterature review

  31. Molecular imaging of myocardial infarction

    Jivraj, N., Phinikaridou, A., Shah, A. M. & Botnar, R. M., Jan 2014, In : Basic Research in Cardiology. 109, 1, p. N/A 16 p., 397.

    Research output: Contribution to journalLiterature review

  32. 2013
  33. Autophagy-mediated degradation is necessary for regression of cardiac hypertrophy during ventricular unloading

    Oyabu, J., Yamaguchi, O., Hikoso, S., Takeda, T., Oka, T., Murakawa, T., Yasui, H., Ueda, H., Nakayama, H., Taneike, M., Omiya, S., Shah, A. M., Nishida, K. & Otsu, K., 29 Nov 2013, In : Biochemical and Biophysical Research Communications. 441, 4, p. 787-792 6 p.

    Research output: Contribution to journalArticle

  34. Ionizing radiation regulates cardiac Ca handling via increased ROS and activated CaMKII

    Sag, C. M., Wolff, H. A., Neumann, K., Opiela, M-K., Zhang, J., Steuer, F., Sowa, T., Gupta, S., Schirmer, M., Huenlich, M., Rave-Fraenk, M., Hess, C. F., Anderson, M. E., Shah, A. M., Christiansen, H. & Maier, L. S., 26 Sep 2013, In : Basic Research in Cardiology. 108, 6, p. N/A 15 p., 385.

    Research output: Contribution to journalArticle

  35. Decreased Nox4 levels in the myocardium of patients with aortic valve stenosis

    Moreno, M. U., Gallego, I., Lopez, B., Gonzalez, A., Fortuno, A., San Jose, G., Valencia, F., Jose Gomez-Doblas, J., de Teresa, E., Shah, A. M., Diez, J. & Zalba, G., Sep 2013, In : Clinical Science. 125, 5-6, p. 291-300 10 p., N/A.

    Research output: Contribution to journalArticle

  36. Novel aspects of ROS signalling in heart failure

    Hafstad, A. D., Nabeebaccus, A. A. & Shah, A. M., Jun 2013, In : Basic Research in Cardiology. 108, 4, 11 p., 359.

    Research output: Contribution to journalLiterature review

  37. Smooth Muscle Cells Differentiated From Reprogrammed Embryonic Lung Fibroblasts Through DKK3 Signaling Are Potent for Tissue Engineering of Vascular Grafts

    Karamariti, E., Margariti, A., Winkler, B., Wang, X., Hong, X., Baban, D., Ragoussis, J., Huang, Y., Han, J-D. J., Wong, M. M., Sag, C. M., Shah, A. M., Hu, Y. & Xu, Q., 24 May 2013, In : Circulation Research. 112, 11, p. 1433-43 11 p.

    Research output: Contribution to journalArticle

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