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Research Outputs

  1. 2017
  2. Risk of uveitis and inflammatory bowel disease in people with psoriatic arthritis: a population-based cohort study

    Charlton, R., Green, A., Shaddick, G., Snowball, J., Nightingale, A., Tillett, W., Smith, C., McHugh, N. & PROMPT study group, 1 Nov 2017, In : Annals of the rheumatic diseases.

    Research output: Contribution to journalArticle

  3. Differential Drug Survival of Second-Line Biologic Therapies In Patients with Psoriasis: Observational Cohort Study from the British Association of Dermatologists Biologic Interventions Register (BADBIR)

    Iskandar, I. Y. K., Warren, R. B., Lunt, M., Mason, K. J., Evans, I., McElhone, K., Smith, C., Reynolds, N. J., Ashcroft, D. M., Griffiths, C. E. M. & BADBIR Study Group, 25 Oct 2017, In : Journal of Investigative Dermatology.

    Research output: Contribution to journalArticle

  4. Risk of Serious Infection in Patients with Psoriasis on Biologic Therapies: a Prospective Cohort Study from the British Association of Dermatologists Biologic Interventions Register (BADBIR)

    Yiu, Z. Z. N., Smith, C. H., Ashcroft, D. M., Lunt, M., Walton, S., Murphy, R., Reynolds, N. J., Ormerod, A. D., Griffiths, C. E. M. & Warren, R. B., Oct 2017, In : Journal of Investigative Dermatology.

    Research output: Contribution to journalArticle

  5. Genetic architecture of acne vulgaris

    Lichtenberger, R., Simpson, M. A., Smith, C., Barker, J. & Navarini, A. A., 24 Sep 2017, In : Journal of The European Academy of Dermatology and Venereology.

    Research output: Contribution to journalArticle

  6. Treatment of severe, chronic hand eczema: results from a UK-wide survey

    Smith, I. L., Brown, S., Nixon, J., Cowdell, F. C., Ersser, S., Fernandez, C., Goodfield, M., Green, C. M., Hampton, P., Lear, J. T., Smith, C. H., Sunderland, L., Tubeuf, S. & Wittmann, M., Mar 2017, In : Clinical and Experimental Dermatology. 42, 2, p. 185-188 4 p.

    Research output: Contribution to journalArticle

  7. Acne and Telomere Length: A New Spectrum between Senescence and Apoptosis Pathways

    Ribero, S., Sanna, M., Visconti, A., Navarini, A., Aviv, A., Glass, D., Spector, T. D., Smith, C., Simpson, M., Barker, J., Mangino, M., Falchi, M. & Bataille, V., Feb 2017, In : Journal of Investigative Dermatology. 137, 2, p. 513-515

    Research output: Contribution to journalLetter

  8. 2016
  9. Patterns of biologic therapy use in the management of psoriasis: cohort study from the British Association of Dermatologists Biologic Interventions Register (BADBIR)

    Iskandar, I. Y. K., Ashcroft, D. M., Warren, R. B., Evans, I., McElhone, K., Owen, C. M., Burden, A. D., Smith, C. H., Reynolds, N. J. & Griffiths, C. E. M., 2 Sep 2016, In : British Journal of Dermatology.

    Research output: Contribution to journalArticle

  10. 2015
  11. Establishing an academic-industrial stratified medicine consortium: Psoriasis stratification to optimize relevant therapy

    Griffiths, C. E. M., Barnes, M. R., Burden, A. D., Nestle, F. O., Reynolds, N. J., Smith, C. H., Warren, R. B. & Barker, J. N. W. N., 1 Dec 2015, In : Journal of Investigative Dermatology. 135, 12, p. 2903-2907 5 p.

    Research output: Contribution to journalArticle

  12. European S3-Guidelines on the systemic treatment of psoriasis vulgaris--Update 2015--Short version--EDF in cooperation with EADV and IPC

    Nast, A., Gisondi, P., Ormerod, A. D., Saiag, P., Smith, C., Spuls, P. I., Arenberger, P., Bachelez, H., Barker, J., Dauden, E., de Jong, E. M., Feist, E., Jacobs, A., Jobling, R., Kemény, L., Maccarone, M., Mrowietz, U., Papp, K. A., Paul, C., Reich, K. & 6 others, Rosumeck, S., Talme, T., Thio, H. B., van de Kerkhof, P., Werner, R. N. & Yawalkar, N., Dec 2015, In : Journal of The European Academy of Dermatology and Venereology. 29, 12, p. 2277-2294 18 p.

    Research output: Contribution to journalArticle

  13. Differential Drug Survival of Biologic Therapies for the Treatment of Psoriasis: A Prospective Observational Cohort Study from the British Association of Dermatologists Biologic Interventions Register (BADBIR)

    Warren, R. B., Smith, C. H., Yiu, Z. Z. N., Ashcroft, D. M., Barker, J. N. W. N., Burden, A. D., Lunt, M., McElhone, K., Ormerod, A. D., Owen, C. M., Reynolds, N. J., Griffiths, C. E. M. & BADBIR Study Group, Nov 2015, In : Journal of Investigative Dermatology. 135, 11, p. 2632-40 9 p.

    Research output: Contribution to journalArticle

  14. Activating CARD14 Mutations are Associated with Generalised Pustular Psoriasis but Rarely Account for Familial Recurrence in Psoriasis Vulgaris

    Berki, D. M., Liu, L., Choon, S-E., David Burden, A., Griffiths, C. E., Navarini, A. A., Tan, E. S., Irvine, A. D., Ranki, A., Ogo, T., Petrof, G., Mahil, S. K., Duckworth, M., Allen, M. H., Vito, P., Trembath, R., McGrath, J., Smith, C. H., Capon, F. & Barker, J. N., 13 Aug 2015, In : Journal of Investigative Dermatology. 135, p. 2964–297

    Research output: Contribution to journalArticle

  15. Demographics and disease characteristics of patients with psoriasis enrolled in the British Association of Dermatologists Biologic Interventions Register

    Iskandar, I. Y. K., Ashcroft, D. M., Warren, R. B., Yiu, Z. Z. N., McElhone, K., Lunt, M., Barker, J. N. W. N., Burden, A. D., Ormerod, A. D., Reynolds, N. J., Smith, C. H. & Griffiths, C. E. M., Aug 2015, In : British Journal of Dermatology. 173, 2, p. 510-8 9 p.

    Research output: Contribution to journalArticle

  16. Psoriasis and cardiometabolic traits: Modest association but distinct genetic architectures

    Koch, M., Baurecht, H., Ried, J. S., Rodriguez, E., Schlesinger, S., Volks, N., Gieger, C., Rückert, I. M., Heinrich, L., Willenborg, C., Smith, C., Peters, A., Thorand, B., Koenig, W., Lamina, C., Jansen, H., Kronenberg, F., Seissler, J., Thiery, J., Rathmann, W. & 14 others, Schunkert, H., Erdmann, J., Barker, J., Nair, R. P., Tsoi, L. C., Elder, J. T., Mrowietz, U., Weichenthal, M., Mucha, S., Schreiber, S., Franke, A., Schmitt, J., Lieb, W. & Weidinger, S., 22 May 2015, In : Journal of Investigative Dermatology. 135, 5, p. 1283-1293 11 p.

    Research output: Contribution to journalArticle

  17. IL36RN mutations define a severe autoinflammatory phenotype of generalized pustular psoriasis

    Hussain, S., Berki, D. M., Choon, S-E., Burden, A. D., Allen, M. H., Arostegui, J. I., Chaves, A., Duckworth, M., Irvine, A. D., Mockenhaupt, M., Navarini, A. A., Seyger, M. M. B., Soler-Palacin, P., Prins, C., Valeyrie-Allanore, L., Vicente, M. A., Trembath, R. C., Smith, C. H., Barker, J. N. & Capon, F., Apr 2015, In : Journal of Allergy and Clinical Immunology. 135, 4, p. 1067-1070.e9 12 p.

    Research output: Contribution to journalArticle

  18. Biological therapies for the treatment of severe psoriasis in patients with previous exposure to biological therapy: a cost-effectiveness analysis

    Sawyer, L. M., Wonderling, D., Jackson, K., Murphy, R., Samarasekera, E. J. & Smith, C. H., Feb 2015, In : PharmacoEconomics. 33, 2, p. 163-77 15 p.

    Research output: Contribution to journalArticle

  19. Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms

    Baurecht, H., Hotze, M., Brand, S., Büning, C., Cormican, P., Corvin, A., Ellinghaus, D., Ellinghaus, E., Esparza-Gordillo, J., Fölster-Holst, R., Franke, A., Gieger, C., Hubner, N., Illig, T., Irvine, A. D., Kabesch, M., Lee, Y. A. E., Lieb, W., Marenholz, I., McLean, W. H. I. & 18 others, Morris, D. W., Mrowietz, U., Nair, R., Nöthen, M. M., Novak, N., O'Regan, G. M., Schreiber, S., Smith, C., Strauch, K., Stuart, P. E., Trembath, R., Tsoi, L. C., Weichenthal, M., Barker, J., Elder, J. T., Weidinger, S., Cordell, H. J. & Brown, S. J., 8 Jan 2015, In : American Journal of Human Genetics. 96, 1, p. 104-120 17 p.

    Research output: Contribution to journalArticle

  20. 2014
  21. Development and testing of new candidate psoriatic arthritis screening questionnaires combining optimal questions from existing tools

    Coates, L. C., Walsh, J., Haroon, M., FitzGerald, O., Aslam, T., Al Balushi, F., Burden, A. D., Burden-Teh, E., Caperon, A. R., Cerio, R., Chattopadhyay, C., Chinoy, H., Goodfield, M. J. D., Kay, L., Kelly, S., Kirkham, B. W., Lovell, C. R., Marzo-Ortega, H., McHugh, N., Murphy, R. & 7 others, Reynolds, N. J., Smith, C. H., Stewart, E. J. C., Warren, R. B., Waxman, R., Wilson, H. E. & Helliwell, P. S., Sep 2014, In : Arthritis care & research. 66, 9, p. 1410-6 7 p.

    Research output: Contribution to journalArticle

  22. Validity of noninvasive markers of methotrexate-induced hepatotoxicity: a retrospective cohort study

    Martyn-Simmons, C. L., Rosenberg, W. M. C., Cross, R., Wong, T., Smith, C. H. & Barker, J. N. W. N., Aug 2014, In : British Journal of Dermatology. 171, 2, p. 267-73 7 p.

    Research output: Contribution to journalArticle

  23. Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris

    Navarini, A. A., Simpson, M. A., Weale, M., Knight, J., Carlavan, I., Reiniche, P., Burden, D. A., Layton, A., Bataille, V., Allen, M., Pleass, R., Pink, A., Creamer, D., English, J., Munn, S., Walton, S., Willis, C., Deret, S., Voegel, J. J., Spector, T. & 4 others, Smith, C. H., Trembath, R. C., Barker, J. N. & Acne Genetic Study Grp, Jun 2014, In : Nature Communications. 5, 6 p., 4020.

    Research output: Contribution to journalArticle

  24. AP1S3 Mutations Are Associated with Pustular Psoriasis and Impaired Toll-like Receptor 3 Trafficking

    Setta-Kaffetzi, N., Simpson, M. A., Navarini, A. A., Patel, V. M., Lu, H-C., Allen, M. H., Duckworth, M., Bachelez, H., Burden, A. D., Choon, S-E., Griffiths, C. E. M., Kirby, B., Kolios, A., Seyger, M. M. B., Prins, C., Smahi, A., Trembath, R. C., Fraternali, F., Smith, C. H., Barker, J. N. & 1 others, Capon, F., May 2014, In : American Journal of Human Genetics. 94, 5, p. 790-797 8 p.

    Research output: Contribution to journalArticle

  25. Characterization of Innate Lymphoid Cells in Human Skin and Blood Demonstrates Increase of NKp44+ILC3 in Psoriasis

    Villanova, F., Flutter, B., Tosi, I., Grys, K., Sreeneebus, H., Perera, G., Chapman, A., Smith, C., Di Meglio, P. & Nestle, F., Apr 2014, In : Journal of Investigative Dermatology. 134, 4, p. 984-991 8 p.

    Research output: Contribution to journalArticle

  26. Psoriasis: guidance on assessment and referral

    Samarasekera, E. J., Smith, C. H. & Natl Inst Hlth Care Excellence, Apr 2014, In : Clinical Medicine. 14, 2, p. 178-182 5 p.

    Research output: Contribution to journalArticle

  27. Psoriatic arthritis screening tools: study design and methodologic challenges - reply from authors

    Coates, L. C., Aslam, T., Al Balushi, F., Burden, A. D., Burden-Teh, E., Caperon, A. R., Cerio, R., Chattopadhyay, C., Chinoy, H., Goodfield, M. J. D., Kay, L., Kelly, S., Kirkham, B., Lovell, C. R., Marzo-Ortega, H., McHugh, N., Murphy, R., Reynolds, N. J., Smith, C. H., Stewart, E. J. C. & 4 others, Warren, R. B., Waxman, R., Wilson, H. E. & Helliwell, P. S., Apr 2014, In : British Journal of Dermatology. 170, 4, p. 995-996 2 p.

    Research output: Contribution to journalLetter

  28. Generalized Pustular Eruptions: Time to Adapt the Disease Taxonomy to the Genetic Architecture?

    Navarini, A. A., Valeyrie-Allanore, L., Setta-Kaffetzi, N., Barker, J. N., Capon, F., Creamer, D., Roujeau, J-C., Sekula, P., Simpson, M. A., Trembath, R. C., Mockenhaupt, M. & Smith, C. H., Feb 2014, In : Journal of Investigative Dermatology. 134, 2, p. 580-581 2 p.

    Research output: Contribution to journalLetter

  29. Loss of IL36RN Function Does Not Confer Susceptibility to Psoriasis Vulgaris

    Berki, D. M., Mahil, S. K., David Burden, A., Trembath, R. C., Smith, C. H., Capon, F. & Barker, J. N., Jan 2014, In : Journal of Investigative Dermatology. 134, 1, p. 271-273 3 p.

    Research output: Contribution to journalLetter

  30. Methotrexate and liver fibrosis in people with psoriasis: A systematic review of observational studies

    Maybury, C. M., Jabbar-Lopez, Z. K., Wong, T., Dhillon, A. P., Barker, J. N. & Smith, C. H., 2014, In : British Journal of Dermatology. 171, 1, p. 17-29 13 p.

    Research output: Contribution to journalArticle

  31. 2013
  32. Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

    Saunders, S. P., Goh, C. S. M., Brown, S. J., Palmer, C. N. A., Porter, R. M., Cole, C., Campbell, L. E., Gierlinski, M., Barton, G. J., Schneider, G., Balmain, A., Prescott, A. R., Weidinger, S., Baurecht, H., Kabesch, M., Gieger, C., Lee, Y. A., Tavendale, R., Mukhopadhyay, S., Turner, S. W. & 14 others, Madhok, V. B., Sullivan, F. M., Relton, C., Burn, J., Meggitt, S., Smith, C. H., Allen, M. A., Barker, J. N. W. N., Reynolds, N. J., Cordell, H. J., Irvine, A. D., McLean, W. H. I., Sandilands, A. & Fallon, P. G., Nov 2013, In : Journal of Allergy and Clinical Immunology. 132, 5, p. 1121-1129 9 p.

    Research output: Contribution to journalArticle

  33. A difficult case of atopic eczema

    Garrett, G. L., Davies, J. B., Fiandeiro, P. T. & Smith, C., 14 Oct 2013, In : BMJ (Clinical research ed.). 347, p. f6010

    Research output: Contribution to journalArticle

  34. Incidence of cardiovascular disease in individuals with psoriasis: A systematic review and meta-analysis

    Samarasekera, E. J., Neilson, J. M., Warren, R. B., Parnham, J. & Smith, C. H., Oct 2013, In : Journal of Investigative Dermatology. 133, 10, p. 2340-2346 7 p.

    Research output: Contribution to journalArticle

  35. Psoriasis and cardiovascular disease: Where is the risk?

    Maybury, C. M., Barker, J. N. & Smith, C. H., Oct 2013, In : Journal of Investigative Dermatology. 133, 10, p. 2308-2311 4 p.

    Research output: Contribution to journalArticle

  36. The 2012 BSR and BHPR guideline for the treatment of psoriatic arthritis with biologics

    Coates, L. C., Tillett, W., Chandler, D., Helliwell, P. S., Korendowych, E., Kyle, S., McInnes, I. B., Oliver, S., Ormerod, A., Smith, C., Symmons, D., Waldron, N., McHugh, N. J. & BSR Clinical Affairs Committee & Standards, Audit and Guidelines Working Group and the BHPR, Oct 2013, In : Rheumatology. 52, 10, p. 1754-7 4 p.

    Research output: Contribution to journalArticle

  37. Predicting treatment response in psoriasis using serum levels of adalimumab and etanercept: a single-centre, cohort study

    Mahil, S. K., Arkir, Z., Richards, G., Lewis, C. M., Barker, J. N. & Smith, C. H., Aug 2013, In : British Journal of Dermatology. 169, 2, p. 306-313 8 p., N/A.

    Research output: Contribution to journalArticle

  38. Rare Variations in IL36RN in Severe Adverse Drug Reactions Manifesting as Acute Generalized Exanthematous Pustulosis

    Navarini, A. A., Valeyrie-Allanore, L., Setta-Kaffetzi, N., Barker, J. N., Capon, F., Creamer, D., Roujeau, J-C., Sekula, P., Simpson, M. A., Trembath, R. C., Mockenhaupt, M. & Smith, C. H., Jul 2013, In : Journal of Investigative Dermatology. 133, 7, p. 1904-1907 4 p.

    Research output: Contribution to journalLetter

  39. Topical therapies for the treatment of localized plaque psoriasis in primary care: a cost-effectiveness analysis

    Sawyer, L., Samarasekera, E. J., Wonderling, D. & Smith, C. H., May 2013, In : British Journal of Dermatology. 168, 5, p. 1095-105 11 p.

    Research output: Contribution to journalArticle

  40. Topical therapies for the treatment of plaque psoriasis: systematic review and network meta-analyses

    Samarasekera, E. J., Sawyer, L., Wonderling, D., Tucker, R. & Smith, C. H., May 2013, In : British Journal of Dermatology. 168, 5, p. 954-67 14 p.

    Research output: Contribution to journalArticle

  41. Comparison of three screening tools to detect psoriatic arthritis in patients with psoriasis (CONTEST study)

    Coates, L. C., Aslam, T., Al Balushi, F., Burden, A. D., Burden-The, E., Caperon, A. R., Cerio, R., Chattopadhyay, C., Chinoy, H., Goodfield, M. J. D., Kay, L., Kelly, S., Kirkham, B., Lovell, C. R., Marzo-Ortega, H., McHugh, N., Murphy, R., Reynolds, N. J., Smith, C. H., Stewart, E. J. C. & 4 others, Warren, R. B., Waxman, R., Wilson, H. E. & Helliwell, P. S., Apr 2013, In : British Journal of Dermatology. 168, 4, p. 802-807 6 p.

    Research output: Contribution to journalArticle

  42. Rare Pathogenic Variants in IL36RN Underlie a Spectrum of Psoriasis-Associated Pustular Phenotypes

    Setta-Kaffetzi, N., Navarini, A. A., Patel, V. M., Pullabhatla, V., Pink, A., Choon, S-E., Allen, M. A., Burden, A. D., Griffiths, C. E. M., Seyger, M. M. B., Kirby, B., Trembath, R. C., Simpson, M. A., Smith, C. H., Capon, F. & Barker, J. N., 10 Jan 2013, In : Journal of Investigative Dermatology. 133, 5, p. 1366-1369 4 p.

    Research output: Contribution to journalLetter

  43. 2012
  44. Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

    Tsoi, L. C., Spain, S. L., Knight, J., Ellinghaus, E., Stuart, P. E., Capon, F., Ding, J., Li, Y., Tejasvi, T., Gudjonsson, J. E., Kang, H. M., Allen, M. H., McManus, R., Novelli, G., Samuelsson, L., Schalkwijk, J., Ståhle, M., Burden, A. D., Smith, C. H., Cork, M. J. & 31 others, Estivill, X., Bowcock, A. M., Krueger, G. G., Weger, W., Worthington, J., Tazi-Ahnini, R., Nestle, F. O., Hayday, A., Hoffmann, P., Winkelmann, J., Wijmenga, C., Langford, C., Edkins, S., Andrews, R., Blackburn, H., Strange, A., Band, G., Pearson, R. D., Vukcevic, D., Spencer, C. C. A., Onoufriadis, A., Weale, M. E., Campbell, L. E., Mathew, C. G., Plomin, R., Viswanathan, A. C., Gray, E., Weston, P., Barker, J. N. W. N., Trembath, R. C. & Collaborative Association Study of Psoriasis (CASP), Dec 2012, In : Nature Genetics. 44, 12, p. 1341-1348 8 p.

    Research output: Contribution to journalArticle

  45. The British Association of Dermatologists' Biologic Interventions Register (BADBIR): design, methodology and objectives

    Burden, A. D., Warren, R. B., Kleyn, C. E., McElhone, K., Smith, C. H., Reynolds, N. J., Ormerod, A. D. & Griffiths, C. E. M., Mar 2012, In : British Journal of Dermatology. 166, 3, p. 545 - 554 10 p.

    Research output: Contribution to journalArticle

  46. Biopharmaceuticals and biosimilars in psoriasis: what the dermatologist needs to know

    Strober, B. E., Armour, K., Romiti, R., Smith, C., Tebbey, P. W., Menter, A. & Leonardi, C., Feb 2012, In : Journal of the American Academy of Dermatology. 66, 2, p. 317-22 6 p.

    Research output: Contribution to journalArticle

  47. Practical experience of ustekinumab in the treatment of psoriasis: experience from a multicentre, retrospective case cohort study across the UK and Ireland

    Laws, P. M., Downs, A. M., Parslew, R., Dever, B., Smith, C. H., Barker, J. N., Moriarty, B., Murphy, R., Kirby, B., Burden, A. D., McBride, S., Anstey, A. V., O'Shea, S., Ralph, N., Buckley, C., Griffiths, C. E. M. & Warren, R. B., Jan 2012, In : British Journal of Dermatology. 166, 1, p. 189 - 195 7 p.

    Research output: Contribution to journalArticle

  48. 2011
  49. Clinical and pharmacogenetic influences on response to hydroxychloroquine in discoid lupus erythematosus: a retrospective cohort study

    Wahie, S., Daly, A. K., Cordell, H. J., Goodfield, M. J., Jones, S. K., Lovell, C. R., Carmichael, A. J., Carr, M. M., Drummond, A., Natarajan, S., Smith, C. H., Reynolds, N. J. & Meggitt, S. J., Oct 2011, In : Journal of Investigative Dermatology. 131, 10, p. 1981-6 6 p.

    Research output: Contribution to journalArticle

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