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Research Outputs

  1. 2017
  2. Refinement of a Methodology for Untargeted Detection of Serum Albumin Adducts in Human Populations

    Preston, G. W., Plusquin, M., Sozeri, O., Van Veldhoven, K., Bastian, L., Nawrot, T. S., Chadeau-Hyam, M. & Phillips, D. H., 18 Dec 2017, In : Chemical Research in Toxicology. 30, 12, p. 2120-2129

    Research output: Contribution to journalArticle

  3. Glueball dark matter in non-standard cosmologies

    Acharya, B. S., Fairbairn, M. & Hardy, E., Jul 2017, In : Journal of High Energy Physics. 2017, 7, p. 1-28 29 p., 100.

    Research output: Contribution to journalArticle

  4. Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone

    Arlt, V. M., Meinl, W., Florian, S., Nagy, E., Barta, F., Thomann, M., Mrizova, I., Krais, A. M., Liu, M., Richards, M., Mirza, A., Kopka, K., Phillips, D. H., Glatt, H., Stiborova, M. & Schmeiser, H. H., Apr 2017, In : Archives of Toxicology. 91, 4, p. 1957-1975

    Research output: Contribution to journalArticle

  5. Nutlin-3a selects for cells harbouring TP53 mutations

    Kucab, J. E., Hollstein, M., Arlt, V. M. & Phillips, D. H., 15 Feb 2017, In : International Journal of Cancer. 140, 4, p. 877-887 11 p.

    Research output: Contribution to journalArticle

  6. Search for Magnetic Monopoles with the MoEDAL Forward Trapping Detector in 13 TeV Proton-Proton Collisions at the LHC

    Acharya, B., Alexandre, J., Baines, S., Benes, P., Bergmann, B., Bernabéu, J., Branzas, H., Campbell, M., Caramete, L., Cecchini, S., De Montigny, M., De Roeck, A., Ellis, J. R., Fairbairn, M., Felea, D., Flores, J., Frank, M., Frekers, D., Garcia, C., Hirt, A. M. & 50 others, Janecek, J., Kalliokoski, M., Katre, A., Kim, D. W., Kinoshita, K., Korzenev, A., Lacarrère, D. H., Lee, S. C., Leroy, C., Lionti, A., Mamuzic, J., Margiotta, A., Mauri, N., Mavromatos, N. E., Mermod, P., Mitsou, V. A., Orava, R., Parker, B., Pasqualini, L., Patrizii, L., Pǎvǎlaş, G. E., Pinfold, J. L., Popa, V., Pozzato, M., Pospisil, S., Rajantie, A., Ruiz De Austri, R., Sahnoun, Z., Sakellariadou, M., Sarkar, S., Semenoff, G., Shaa, A., Sirri, G., Sliwa, K., Soluk, R., Spurio, M., Srivastava, Y. N., Suk, M., Swain, J., Tenti, M., Togo, V., Tuszyński, J. A., Vento, V., Vives, O., Vykydal, Z., Whyntie, T., Widom, A., Willems, G., Yoon, J. H. & Zgura, I. S., 10 Feb 2017, In : Physical Review Letters. 118, 6, 061801.

    Research output: Contribution to journalArticle

  7. Measurement of the prompt J/ψψ pair production cross-section in pp collisions at s√=8s=8 TeV with the ATLAS detector

    ATLAS Collaboration, 7 Feb 2017, In : European Physical Journal C. 77, 34 p., 76.

    Research output: Contribution to journalArticle

  8. Measurements of ψ(2S) and X(3872) → J/ψπ+π− production in pp collisions at s√=8s=8 TeV with the ATLAS detector

    ATLAS Collaboration & Acharya, B. S., 26 Jan 2017, In : Journal of High Energy Physics. 2017, 1, 43 p., 117.

    Research output: Contribution to journalArticle

  9. 2016
  10. From the exposome to mechanistic understanding of chemical-induced adverse effects

    Escher, B. I., Hackermüller, J., Polte, T., Scholz, S., Aigner, A., Altenburger, R., Böhme, A., Bopp, S. K., Brack, W., Busch, W., Chadeau-Hyam, M., Covaci, A., Eisenträger, A., Galligan, J. J., Garcia-Reyero, N., Hartung, T., Hein, M., Herberth, G., Jahnke, A., Kleinjans, J. & 16 others, Klüver, N., Krauss, M., Lamoree, M., Lehmann, I., Luckenbach, T., Miller, G. W., Müller, A., Phillips, D. H., Reemtsma, T., Rolle-Kampczyk, U., Schüürmann, G., Schwikowski, B., Tan, Y-M., Trump, S., Walter-Rohde, S. & Wambaugh, J. F., 8 Dec 2016, In : Environment International.

    Research output: Contribution to journalArticle

  11. Neutrino mass from M theory SO(10)

    Acharya, B. S., Bozek, K., Romão, M. C., King, S. F. & Pongkitivanichkul, C., 29 Nov 2016, In : Journal of High Energy Physics. 2016, 11, 32 p., 173.

    Research output: Contribution to journalArticle

  12. Study of hard double-parton scattering in four-jet events in pp collisions at s = 7 backslashsqrts=7 TeV with the ATLAS experiment

    The ATLAS Collaboration, Aaboud, M., Aad, G. & et al, 21 Nov 2016, In : Journal of High Energy Physics. 2016, 11, 1 p., 110.

    Research output: Contribution to journalArticle

  13. Mutational signatures associated with tobacco smoking in human cancer

    Alexandrov, L. B., Ju, Y. S., Haase, K., Van Loo, P., Martincorena, I., Nik-Zainal, S., Totoki, Y., Fujimoto, A., Nakagawa, H., Shibata, T., Campbell, P. J., Vineis, P., Phillips, D. H. & Stratton, M. R., 4 Nov 2016, In : Science. 354, 6312, p. 618-622 5 p.

    Research output: Contribution to journalArticle

  14. Lightest Visible-Sector Supersymmetric Particle is Likely to be Unstable

    Acharya, B. S., Ellis, S. A. R., Kane, G. L., Nelson, B. D. & Perry, M. J., 28 Oct 2016, In : Physical Review Letters. 117, 18, 4 p., 181802.

    Research output: Contribution to journalArticle

  15. NADH:Cytochrome b5 reductase and cytochrome b5 can act as sole electron donors to human cytochrome P450 1A1-mediated oxidation and DNA adduct formation by benzo[a]pyrene

    Stiborova, M., Indra, R., Moserova, M., Frei, E., Schmeiser, H. H., Kopka, K., Phillips, D. H. & Arlt, V. M., 15 Aug 2016, In : Chemical Research in Toxicology. 29, 8, p. 1325-1334

    Research output: Contribution to journalArticle

  16. Transcriptional profiling of the mouse hippocampus supports an NMDAR-mediated neurotoxic mode of action for benzo[a]pyrene

    Chepelev, N. L., Long, A. S., Bowers, W. J., Gagné, R., Williams, A., Kuo, B., Phillips, D. H., Arlt, V. M., White, P. A. & Yauk, C. L., Jun 2016, In : Environmental and Molecular Mutagenesis. 57, 5, p. 350–363

    Research output: Contribution to journalArticle

  17. The axiverse induced dark radiation problem

    Acharya, B. & Pongkitivanichkul, C., 1 Apr 2016, In : Journal of High Energy Physics. 2016, 4, 9.

    Research output: Contribution to journalArticle

  18. The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice

    Krais, A. M., Speksnijder, E. N., Melis, J. P. M., Indra, R., Moserova, M., Godschalk, R. W., van Schooten, F-J., Seidel, A., Kopka, K., Schmeiser, H. H., Stiborova, M., Phillips, D. H., Luijten, M. & Arlt, V. M., Apr 2016, In : Archives of Toxicology. 90, 4, p. 839-851 13 p.

    Research output: Contribution to journalArticle

  19. Metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and DNA adduct formation depends on p53: studies in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice

    Krais, A. M., Speksnijder, E. N., Melis, J. P. M., Singh, R., Caldwell, A., Gamboa da Costa, G., Luijten, M., Phillips, D. H. & Arlt, V. M., 15 Feb 2016, In : International Journal of Cancer. 138, 4, p. 976–982

    Research output: Contribution to journalArticle

  20. Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism

    Wohak, L., Krais, A. M., Kucab, J. E., Stertmann, J., Ovrebø, S., Seidel, A., Phillips, D. H. & Arlt, V. M., 1 Feb 2016, In : Archives of Toxicology. 90, 2, p. 291-304 14 p.

    Research output: Contribution to journalArticle

  21. Transcriptional profiling of dibenzo[def, p]chrysene-induced spleen atrophy provides mechanistic insights into its immunotoxicity in mutamouse

    Chepelev, N. L., Long, A. S., Williams, A., Kuo, B., Gagné, R., Kennedy, D. A., Phillips, D. H., Arlt, V. M., White, P. A. & Yauk, C. L., 1 Jan 2016, In : Toxicological Sciences. 149, 1, p. 251-268 18 p.

    Research output: Contribution to journalArticle

  22. Search for invisible decays of a Higgs boson using vector-boson fusion in pp collisions at (Formula Presented.) TeV with the ATLAS detector

    The ATLAS Collaboration, Aad, G., Abbott, B. & et al, Jan 2016, In : Journal of High Energy Physics. 2016, 1, p. 1-43 44 p., 172.

    Research output: Contribution to journalArticle

  23. Search for magnetic monopoles with the MoEDAL prototype trapping detector in 8 TeV proton-proton collisions at the LHC

    The MoEDAL collaboration, MDAL. C., Acharya, B., Alexandre, J., Bendtz, K., Benes, P., Bernabéu, J., Campbell, M., Cecchini, S., Chwastowski, J., Chatterjee, A., de Montigny, M., Derendarz, D., De Roeck, A., Ellis, J. R., Fairbairn, M., Felea, D., Frank, M., Frekers, D., Garcia, C., Giacomelli, G. & 50 others, Hasegan, D., Kalliokoski, M., Katre, A., Kim, D. W., King, M. G. L., Kinoshita, K., Lacarrère, D. H., Lee, S. C., Leroy, C., Lionti, A., Margiotta, A., Mauri, N., Mavromatos, N. E., Mermod, P., Milstead, D., Mitsou, V. A., Orava, R., Parker, B., Pasqualini, L., Patrizii, L., Păvălas, G. E., Pinfold, J. L., Platkevič, M., Popa, V., Pozzato, M., Pospisil, S., Rajantie, A., Sahnoun, Z., Sakellariadou, M., Sarkar, S., Semenoff, G., Sirri, G., Sliwa, K., Soluk, R., Spurio, M., Srivastava, Y. N., Staszewski, R., Suk, M., Swain, J., Tenti, M., Togo, V., Trzebinski, M., Tuszynski, J. A., Vento, V., Vives, O., Vykydal, Z., Whyntie, T., Widom, A., Willems, G. & Yoon, J. H., 2016, In : Journal of High Energy Physics. 2016, 8, 67.

    Research output: Contribution to journalArticle

  24. 2015
  25. TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts

    Kucab, J. E., Zwart, E. P., van Steeg, H., Luijten, M., Schmeiser, H. H., Phillips, D. H. & Arlt, V. M., 8 Dec 2015, In : DNA REPAIR.

    Research output: Contribution to journalArticle

  26. The genome as a record of environmental exposure

    Nik-Zainal, S., Kucab, J. E., Morganella, S., Glodzik, D., Alexandrov, L. B., Arlt, V. M., Weninger, A., Hollstein, M., Stratton, M. R. & Phillips, D. H., Nov 2015, In : Mutagenesis. 30, 6, p. 763-770 8 p.

    Research output: Contribution to journalArticle

  27. Pulmonary inflammation impacts on CYP1A1-mediated respiratory tract DNA damage induced by the carcinogenic air pollutant benzo[a]pyrene

    Arlt, V. M., Krais, A., Godschalk, R. W., Riffo-Vasquez, Y., Mrizova, I., Roufosse, C. A., Corbin, C., Shi, Q., Frei, E., Stiborova, M., van Schooten, F-J., Phillips, D. H. & Spina, D., 23 Apr 2015, In : Toxicological sciences : an official journal of the Society of Toxicology. 146, 2, p. 213-225 13 p.

    Research output: Contribution to journalArticle

  28. TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts

    Kucab, J. E., van Steeg, H., Luijten, M., Schmeiser, H. H., White, P. A., Phillips, D. H. & Arlt, V. M., 1 Mar 2015, In : Mutation Research. 773, p. 48-62 15 p.

    Research output: Contribution to journalArticle

  29. Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts

    Krais, A. M., Mühlbauer, K-R., Kucab, J. E., Chinbuah, H., Cornelius, M. G., Wei, Q-X., Hollstein, M., Phillips, D. H., Arlt, V. M. & Schmeiser, H. H., Feb 2015, In : Toxicology in Vitro. 29, 1, p. 34-43 10 p.

    Research output: Contribution to journalArticle

  30. Constraints on new phenomena via Higgs boson couplings and invisible decays with the ATLAS detector

    The ATLAS Collaboration, Aad, G., Abbott, B. & et al, 2015, In : Journal of High Energy Physics. 2015, 11, 52 p., 206.

    Research output: Contribution to journalArticle

  31. 2014
  32. Benzo pyrene-induced DNA adducts and gene expression profiles in target and non-target organs for carcinogenesis in mice

    Zuo, J., Brewer, D. S., Arlt, V. M., Cooper, C. S. & Phillips, D. H., 8 Oct 2014, In : BMC GENOMICS. 15, 20 p., 880.

    Research output: Contribution to journalArticle

  33. Cytochronne b(5) and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions

    Stiborová, M., Moserová, M., Cerná, V., Indra, R., Dračínský, M., Sulc, M., Henderson, C. J., Wolf, C. R., Schmeiser, H. H., Phillips, D. H., Frei, E. & Arlt, V. M., 6 Apr 2014, In : Toxicology. 318, p. 1-12 12 p.

    Research output: Contribution to journalArticle

  34. Protective action of n-3 fatty acids on benzo[a]pyrene-induced apoptosis through the plasma membrane remodeling-dependent NHE1 pathway

    Dendelé, B., Tekpli, X., Hardonnière, K., Holme, J. A., Debure, L., Catheline, D., Arlt, V. M., Nagy, E., Phillips, D. H., Ovrebø, S., Mollerup, S., Poët, M., Chevanne, M., Rioux, V., Dimanche-Boitrel, M-T., Sergent, O. & Lagadic-Gossmann, D., 25 Jan 2014, In : Chemico-Biological Interactions. 207, N/A, p. 41-51 11 p., N/A.

    Research output: Contribution to journalArticle

  35. 2013
  36. The GSTM1null (deletion) and MGMT84 rs12917 (Phe/Phe) haplotype are associated with bulky DNA adduct levels in human leukocytes

    Molina, E., Pérez-Morales, R., Rubio, J., Petrosyan, P., Cadena, L. H., Arlt, V. M., Phillips, D. H. & Gonsebatt, M. E., 12 Dec 2013, In : Mutation Research. 758, 1-2, p. 62-68 7 p., N/A.

    Research output: Contribution to journalArticle

  37. 2012
  38. NAD(P)H:quinone oxidoreductase expression in Cyp1a-knockout and CYP1A-humanized mouse lines and its effect on bioactivation of the carcinogen aristolochic acid I

    Levova, K., Moserova, M., Nebert, D. W., Phillips, D. H., Frei, E., Schmeiser, H. H., Arlt, V. M. & Stiborova, M., 15 Dec 2012, In : Toxicology and Applied Pharmacology. 265, 3, p. 360-367 8 p.

    Research output: Contribution to journalArticle

  39. Polycyclic aromatic hydrocarbons as skin carcinogens: Comparison of benzo [a]pyrene, dibenzo[def,p]chrysene and three environmental mixtures in the FVB/N mouse

    Siddens, L. K., Larkin, A., Krueger, S. K., Bradfield, C. A., Waters, K. M., Tilton, S. C., Pereira, C. B., Loehr, C. V., Arlt, V. M., Phillips, D. H., Williams, D. E. & Baird, W. M., 1 Nov 2012, In : Toxicology and Applied Pharmacology. 264, 3, p. 377-386 10 p.

    Research output: Contribution to journalArticle

  40. Exposure to benzo[a]pyrene of Hepatic Cytochrome P450 Reductase Null (HRN) and P450 Reductase Conditional Null (RCN) mice: Detection of benzo[a]pyrene diol epoxide-DNA adducts by immunohistochemistry and 32P-postlabelling

    Arlt, V. M., Poirier, M. C., Sykes, S. E., John, K., Moserova, M., Stiborova, M., Wolf, C. R., Henderson, C. J. & Phillips, D. H., 3 Sep 2012, In : Toxicology Letters. 213, 2, p. 160-166 7 p.

    Research output: Contribution to journalArticle

  41. Subchronic oral exposure to benzo(a)pyrene leads to distinct transcriptomic changes in the lungs that are related to carcinogenesis

    Labib, S., Yauk, C., Williams, A., Arlt, V. M., Phillips, D. H., White, P. A. & Halappanavar, S., Sep 2012, In : Toxicological Sciences. 129, 1, p. 213-224 12 p.

    Research output: Contribution to journalArticle

  42. Bioactivation versus detoxication of the urothelial carcinogen aristolochic acid I by human cytochrome P450 1A1 and 1A2

    Stiborová, M., Levová, K., Bárta, F., Shi, Z., Frei, E., Schmeiser, H. H., Nebert, D. W., Phillips, D. H. & Arlt, V. M., Feb 2012, In : Toxicological Sciences. 125, 2, p. 345 - 358 14 p.

    Research output: Contribution to journalArticle

  43. 2011
  44. Whole body exposure of mice to secondhand smoke induces dose-dependent and persistent promutagenic DNA adducts in the lung

    Kim, S-I., Arlt, V. M., Yoon, J-I., Cole, K. J., Pfeifer, G. P., Phillips, D. H. & Besaratinia, A., 1 Nov 2011, In : Mutation Research. 716, 1-2, p. 92 - 98 7 p.

    Research output: Contribution to journalArticle

  45. Influence of cell cycle on responses of MCF-7 cells to benzo[a]pyrene

    Hamouchene, H., Arlt, V. M., Giddings, I. & Phillips, D. H., 29 Jun 2011, In : BMC GENOMICS. 12, 16 p., 333.

    Research output: Contribution to journalArticle

  46. Role of Cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the Hepatic NADPH:Cytochrome P450 Reductase Null (HRN) mouse model

    Levova, K., Moserova, M., Kotrbova, V., Sulc, M., Henderson, C. J., Wolf, C. R., Phillips, D. H., Frei, E., Schmeiser, H. H., Mares, J., Arlt, V. M. & Stiborova, M., May 2011, In : Toxicological Sciences. 121, 1, p. 43 - 56 14 p.

    Research output: Contribution to journalArticle

  47. 2010
  48. Linking environmental carcinogen exposure to TP53 mutations in human tumours using the human TP53 knock-in (Hupki) mouse model

    Kucab, J. E., Phillips, D. & Arlt, V. M., Jun 2010, In : FEBS Journal. 277, 12, p. 2567 - 2583 17 p.

    Research output: Contribution to journalLiterature review

  49. 2009
  50. The genotoxic air pollutant 3-nitrobenzanthrone and its reactive metabolite N-hydroxy-3-aminobenzanthrone lack initiating and complete carcinogenic activity in NMRI mouse skin

    Schmeiser, H. H., Fuerstenberger, G., Takamura-Enya, T., Phillips, D. & Arlt, V., 18 Oct 2009, In : Cancer Letters. 284, 1, p. 21 - 29 9 p.

    Research output: Contribution to journalArticle

  51. 3-Aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone, induces biotransformation enzymes in rat kidney and lung

    Stiborova, M., Dracinska, H., Martinkova, M., Mizerovska, J., Hudecek, J., Hodek, P., Liberda, J., Frei, E., Schmeiser, H. H., Phillips, D. & Arlt, V., 31 May 2009, In : Mutation Research-Genetic Toxicology And Environmental Mutagenesis. 676, 1-2, p. 93-101 9 p.

    Research output: Contribution to journalArticle

  52. Genotoxicity: damage to DNA and its consequences

    Phillips, D. H. & Arlt, V. M., 2009, Molecular, Clinical and Environmental Toxicology. Luch, A. (ed.). Basel: Birkhäuser Verlag, Vol. 1. p. 87-110 23 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  53. 2008
  54. Genotoxicity of 3-nitrobenzanthrone and 3-aminobenzanthrone in Muta™Mouse and lung epithelial cells derived from Muta™Mouse

    Arlt, V. M., Gingerich, J., Schmeiser, H. H., Phillips, D. H., Douglas, G. R. & White, P. A., Nov 2008, In : Mutagenesis. 23, 6, p. 483-490 8 p.

    Research output: Contribution to journalArticle

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