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Research Outputs

  1. 2015
  2. TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts

    Kucab, J. E., Zwart, E. P., van Steeg, H., Luijten, M., Schmeiser, H. H., Phillips, D. H. & Arlt, V. M., 8 Dec 2015, In : DNA REPAIR.

    Research output: Contribution to journalArticle

  3. A Randomized Trial of Progesterone in Women with Recurrent Miscarriages

    Coomarasamy, A., Williams, H., Truchanowicz, E., Seed, P. T., Small, R., Quenby, S., Gupta, P., Dawood, F., Koot, Y. E. M., Bender Atik, R., Bloemenkamp, K. W. M., Brady, R., Briley, A. L., Cavallaro, R., Cheong, Y. C., Chu, J. J., Eapen, A., Ewies, A., Hoek, A., Kaaijk, E. M. & 15 others, Koks, C. A. M., Li, T-C., MacLean, M., Mol, B. W., Moore, J., Ross, J. A., Sharpe, L., Stewart, J., Vaithilingam, N., Farquharson, R. G., Kilby, M. D., Khalaf, Y., Goddijn, M., Regan, L. & Rai, R., 26 Nov 2015, In : New England Journal of Medicine. 373, 22, p. 2141-8 8 p.

    Research output: Contribution to journalArticle

  4. The genome as a record of environmental exposure

    Nik-Zainal, S., Kucab, J. E., Morganella, S., Glodzik, D., Alexandrov, L. B., Arlt, V. M., Weninger, A., Hollstein, M., Stratton, M. R. & Phillips, D. H., Nov 2015, In : Mutagenesis. 30, 6, p. 763-770 8 p.

    Research output: Contribution to journalArticle

  5. Effect of a behavioural intervention in obese pregnant women (the UPBEAT study): a multicentre, randomised controlled trial

    Poston, L., Bell, R., Croker, H., Flynn, A. C., Godfrey, K. M., Goff, L., Hayes, L., Khazaezadeh, N., Nelson, S. M., Oteng-Ntim, E., Pasupathy, D., Patel, N., Robson, S. C., Sandall, J., Sanders, T. A. B., Sattar, N., Seed, P. T., Wardle, J., Whitworth, M. K., Briley, A. L. & 1 others, UPBEAT Trial Consortium, Oct 2015, In : The Lancet Diabetes and Endocrinology. 3, 10, p. 767-777 11 p.

    Research output: Contribution to journalArticle

  6. Zygosity differences in height and body mass index of twins from infancy to old age: A study of the CODATwins project

    Jelenkovic, A., Yokoyama, Y., Sund, R., Honda, C., Bogl, L. H., Aaltonen, S., Ji, F., Ning, F., Pang, Z., Ordoñana, J. R., Sánchez-Romera, J. F., Colodro-Conde, L., Burt, S. A., Klump, K. L., Medland, S. E., Montgomery, G. W., Kandler, C., McAdams, T., Eley, T. C., Gregory, A. M. & 110 others, Saudino, K. J., Dubois, L., Boivin, M., Tarnoki, A. D., Tarnoki, D. L., Haworth, C. M. A., Plomin, R., Öncel, S. Y., Aliev, F., Stazi, M. A., Fagnani, C., D'Ippolito, C., Craig, J. M., Saffery, R., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Rijsdijk, F., Spector, T., Mangino, M., Lachance, G., Gatz, M., Butler, D. A., Bayasgalan, G., Narandalai, D., Freita, D. L., Maia, J. A., Harden, K. P., Tucker-Drob, E. M., Kim, B., Chong, Y., Hong, C., Shin, H. J., Christensen, K., Skytthe, A., Kyvik, K. O., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Cozen, W., Hwang, A. E., Mack, T. M., He, M., Ding, X., Chang, B., Silberg, J. L., Eaves, L. J., Maes, H. H., Cutler, T. L., Hopper, J. L., Aujard, K., Magnusson, P. K. E., Pedersen, N. L., Dahl Aslan, A. K., Song, Y. M., Yang, S., Lee, K., Baker, L. A., Tuvblad, C., Bjerregaard-Andersen, M., Beck-Nielsen, H., Sodemann, M., Heikkilä, K., Tan, Q., Zhang, D., Swan, G. E., Krasnow, R., Jang, K. L., Knafo-Noam, A., Mankuta, D., Abramson, L., Lichtenstein, P., Krueger, R. F., McGue, M., Pahlen, S., Tynelius, P., Duncan, G. E., Buchwald, D., Corley, R. P., Huibregtse, B. M., Nelson, T. L., Whitfield, K. E., Franz, C. E., Kremen, W. S., Lyons, M. J., Ooki, S., Brandt, I., Nilsen, T. S., Inui, F., Watanabe, M., Bartels, M., Van Beijsterveldt, T. C. E. M., Wardle, J., Llewellyn, C. H., Fisher, A., Rebato, E., Martin, N. G., Iwatani, Y., Hayakawa, K., Sung, J., Harris, J. R., Willemsen, G., Busjahn, A., Goldberg, J. H., Rasmussen, F., Hur, Y. M., Boomsma, D. I., SØrensen, T. I. A., Kaprio, J. & Silventoinen, K., 17 Sep 2015, In : TWIN RESEARCH AND HUMAN GENETICS. 18, 5, p. 557-570 14 p.

    Research output: Contribution to journalArticle

  7. Accuracy of patient self-report of stroke: A systematic review from the UK biobank stroke outcomes group

    Woodfield, R., Sudlow, C., Al-Shahi Salman, R., Beral, V., Chen, Y., Chen, Z., Dennis, M., Kroll, M., Green, J., Lewington, S., Rothwell, P., Wardlaw, J., Whiteley, W., Wild, S., Wright, L., Zhang, Q., Flaig, R., Danesh, J., Allen, N., Atkinson, M. & 22 others, Blaveri, E., Brannan, R., Brayne, C., Brophy, S., Chaturvedi, N., Collins, R., De Lusignan, S., Denaxas, S., Desai, P., Eastwood, S., Gallacher, J., Hemingway, H., Hotopf, M., Landray, M., Lyons, R., McGilchrist, M., Moller, H., O'Neil, T., Pringle, M., Sprosen, T., Strachan, D. & Sullivan, F., 10 Sep 2015, In : PL o S One . 10, 9, 14 p., e0137538.

    Research output: Contribution to journalArticle

  8. Wellbeing interventions: no evidence they prevent mental illness

    Hotopf, M., Mehta, N., Henderson, M. & Wessely, S., 29 Aug 2015, In : Lancet. 386, 9996, p. 852-853 2 p., 127.

    Research output: Contribution to journalArticle

  9. Prenatal exposure to polycyclic aromatic hydrocarbons/aromatics, BDNF and child development

    Perera, F., Phillips, D. H., Wang, Y., Roen, E., Herbstman, J., Rauh, V., Wang, S. & Tang, D., 21 Aug 2015, In : Environmental Research. 142, p. 602-608 7 p., 6575.

    Research output: Contribution to journalArticle

  10. Diagnostic accuracy of placental growth factor and ultrasound parameters to predict the small-for-gestational-age infant in women presenting with reduced symphysis-fundus height

    Griffin, M., Seed, P. T., Webster, L., Myers, J., Mackillop, L., Simpson, N., Anumba, D., Khalil, A., Denbow, M., Sau, A., Hinshaw, K., Von Dadelszen, P., Benton, S., Girling, J., Redman, C. W. G., Chappell, L. C. & Shennan, A. H., 1 Aug 2015, In : Ultrasound in Obstetrics and Gynecology. 46, 2, p. 182-190 9 p.

    Research output: Contribution to journalArticle

  11. The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits

    Silventoinen, K., Jelenkovic, A., Sund, R., Honda, C., Aaltonen, S., Yokoyama, Y., Tarnoki, A. D., Tarnoki, D. L., Ning, F., Ji, F., Pang, Z., Ordo??ana, J. R., S??nchez-romera, J. F., Colodro-conde, L., Burt, S. A., Klump, K. L., Medland, S. E., Montgomery, G. W., Kandler, C., McAdams, T. A. & 106 others, Eley, T. C., Gregory, A. M., Saudino, K. J., Dubois, L., Boivin, M., Haworth, C., Plomin, R., ??ncel, S. Y., Aliev, F., Stazi, M. A., Fagnani, C., D???ippolito, C., Craig, J. M., Saffery, R., Siribaddana, S. H., Hotopf, M., Sumathipala, A., Spector, T., Mangino, M., Lachance, G., Gatz, M., Butler, D. A., Bayasgalan, G., Narandalai, D., Freitas, D. L., Maia, J. A., Harden, K. P., Tucker-drob, E. M., Christensen, K., Skytthe, A., Kyvik, K. O., Hong, C., Chong, Y., Derom, C. A., Vlietinck, R. F., Loos, R. J. F., Cozen, W., Hwang, A. E., Mack, T. M., He, M., Ding, X., Chang, B., Silberg, J. L., Eaves, L. J., Maes, H. H., Cutler, T. L., Hopper, J. L., Aujard, K., Magnusson, P. K. E., Pedersen, N. L., Aslan, A. K. D., Song, Y., Yang, S., Lee, K., Baker, L. A., Tuvblad, C., Bjerregaard-andersen, M., Beck-nielsen, H., Sodemann, M., Heikkil??, K., Tan, Q., Zhang, D., Swan, G. E., Krasnow, R., Jang, K. L., Knafo-noam, A., Mankuta, D., Abramson, L., Lichtenstein, P., Krueger, R. F., Mcgue, M., Pahlen, S., Tynelius, P., Duncan, G. E., Buchwald, D., Corley, R. P., Huibregtse, B. M., Nelson, T. L., Whitfield, K. E., Franz, C. E., Kremen, W. S., Lyons, M. J., Ooki, S., Brandt, I., Nilsen, T. S., Inui, F., Watanabe, M., Bartels, M., Van Beijsterveldt, T. C. E. M., Wardle, J., Llewellyn, C., Fisher, A., Rebato, E., Martin, N. G., Iwatani, Y., Hayakawa, K., Rasmussen, F., Sung, J., Harris, J. R., Willemsen, G., Busjahn, A., Goldberg, J. H., Boomsma, D. I., Hur, Y., S??rensen, T. I. A. & Kaprio, J., Aug 2015, In : TWIN RESEARCH AND HUMAN GENETICS. 18, 4, p. 348-360

    Research output: Contribution to journalArticle

  12. The prevalence and correlates of alcohol use and alcohol use disorders: A population based study in Colombo, Sri Lanka

    Zavos, H. M. S., Siribaddana, S., Ball, H. A., Lynskey, M. T., Sumathipala, A., Rijsdijk, F. V. & Hotopf, M., 14 Jul 2015, In : BMC Psychiatry. 15, 1, 8 p., 158.

    Research output: Contribution to journalArticle

  13. Psychological correlates of fatigue in rheumatoid arthritis: A systematic review

    Matcham, F., Ali, S., Hotopf, M. & Chalder, T., 1 Jul 2015, In : Clinical Psychology Review. 39, p. 16-29 14 p.

    Research output: Contribution to journalArticle

  14. A mismatch between population health literacy and the complexity of health information: An observational study

    Rowlands, G., Protheroe, J., Winkley, J., Richardson, M., Seed, P. T. & Rudd, R., 1 Jun 2015, In : The British journal of general practice : the journal of the Royal College of General Practitioners. 65, 635, p. 379-386 8 p.

    Research output: Contribution to journalArticle

  15. Antidepressants for the treatment of depression in people with cancer (Review)

    Ostuzzi, G., Matcham, F. A. E., Dauchy, S., Barbui, C. & Hotopf, M. H., 1 Jun 2015, In : Cochrane Database of Systematic Reviews. 6, 93 p., CD011006.

    Research output: Contribution to journalArticle

  16. The Effect of Clozapine on Premature Mortality: An Assessment of Clinical Monitoring and Other Potential Confounders

    Hayes, R., Downs, J., Chang, C-K., Jackson, R., Shetty, H., Broadbent, M., Hotopf, M. & Stewart, R., 25 May 2015, In : Schizophrenia Bulletin. 41, 3, p. 644-655 12 p.

    Research output: Contribution to journalArticle

  17. Adverse maternal and perinatal outcomes in pregnant women with sickle cell disease: Systematic review and meta-analysis

    Oteng-Ntim, E., Meeks, D., Seed, P. T., Webster, L., Howard, J., Doyle, P. & Chappell, L. C., 21 May 2015, In : Blood. 125, 21, p. 3316-3325 10 p.

    Research output: Contribution to journalArticle

  18. RIPOSTE: A framework for improving the design and analysis of laboratory-based research

    Masca, N. G. D., Hensor, E. M. A., Cornelius, V., Buffa, F. M., Marriott, H. M., Eales, J. M., Messenger, M. P., Anderson, A. E., Boot, C., Bunce, C., Goldin, R. D., Harris, J., Hinchliffe, R. F., Junaid, H., Kingston, S., Martin-Ruiz, C., Nelson, C. P., Peacock, J., Seed, P. T., Shinkins, B. & 4 others, Staples, K. J., Toombs, J., Wright, A. K. A. & Dawn Teare, M., 7 May 2015, In : eLife. 4, p. 1-27 27 p.

    Research output: Contribution to journalArticle

  19. Quantitative fetal fibronectin to predict preterm birth in asymptomatic women at high risk

    Abbott, D. S., Hezelgrave, N. L., Seed, P. T., Norman, J. E., David, A. L., Bennett, P. R., Girling, J. C., Chandirimani, M., Stock, S. J., Carter, J., Cate, R., Kurtzman, J., Tribe, R. M. & Shennan, A. H., 1 May 2015, In : Obstetrics and Gynecology. 125, 5, p. 1168-1176 9 p.

    Research output: Contribution to journalArticle

  20. The Hepatic Reductase Null (HRN™) and Reductase Conditional Null (RCN) mouse models as suitable tools to study metabolism, toxicity and carcinogenicity of environmental pollutants

    Arlt, V. M., Henderson, C. J., Wolf, C. R., Stiborova, M. & Phillips, D. H., 1 May 2015, In : Toxicology Research. 4, 3, p. 548-562 15 p.

    Research output: Contribution to journalLiterature review

  21. Pulmonary inflammation impacts on CYP1A1-mediated respiratory tract DNA damage induced by the carcinogenic air pollutant benzo[a]pyrene

    Arlt, V. M., Krais, A., Godschalk, R. W., Riffo-Vasquez, Y., Mrizova, I., Roufosse, C. A., Corbin, C., Shi, Q., Frei, E., Stiborova, M., van Schooten, F-J., Phillips, D. H. & Spina, D., 23 Apr 2015, In : Toxicological sciences : an official journal of the Society of Toxicology. 146, 2, p. 213-225 13 p.

    Research output: Contribution to journalArticle

  22. Validation of the SCOFF questionnaire for eating disorders in a multiethnic general population sample

    Solmi, F., Hatch, S. L., Hotopf, M., Treasure, J. & Micali, N., 1 Apr 2015, In : International Journal of Eating Disorders. 48, 3, p. 312-316 5 p.

    Research output: Contribution to journalArticle

  23. TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts

    Kucab, J. E., van Steeg, H., Luijten, M., Schmeiser, H. H., White, P. A., Phillips, D. H. & Arlt, V. M., 1 Mar 2015, In : Mutation Research. 773, p. 48-62 15 p.

    Research output: Contribution to journalArticle

  24. Temporal inabilities and decision-making capacity in depression

    Owen, G., Freyenhagen, F., Hotopf, M. & Martin, W., Mar 2015, In : Phenomenology & the Cognitive Sciences. 14, 1, p. 163-182 20 p.

    Research output: Contribution to journalArticle

  25. Dalteparin for pregnant women with thrombophilia

    Hunt, B. J., Seed, P. T. & Lefkou, E., 21 Feb 2015, In : Lancet. 385, 9969, p. 689 1 p.

    Research output: Contribution to journalLiterature review

  26. Endothelial and platelet microparticles in patients with antiphospholipid antibodies

    Breen, K. A., Sanchez, K., Kirkman, N., Seed, P. T., Parmar, K., Moore, G. W. & Hunt, B. J., 1 Feb 2015, In : Thrombosis Research. 135, 2, p. 368-374 7 p.

    Research output: Contribution to journalArticle

  27. Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts

    Krais, A. M., Mühlbauer, K-R., Kucab, J. E., Chinbuah, H., Cornelius, M. G., Wei, Q-X., Hollstein, M., Phillips, D. H., Arlt, V. M. & Schmeiser, H. H., Feb 2015, In : Toxicology in Vitro. 29, 1, p. 34-43 10 p.

    Research output: Contribution to journalArticle

  28. Association between maternal micronutrient status, oxidative stress and common genetic variants in antioxidant enzymes at 15 weeks' gestation in nulliparous women who subsequently develop pre-eclampsia

    Mistry, H. D., Gill, C. A., Kurlak, L. O., Seed, P. T., Hesketh, J. E., Méplan, C., Schomburg, L., Chappell, L. C., Morgan, L., Poston, L. & on behalf of SCOPE consortium, 1 Jan 2015, In : Free Radical Biology and Medicine. 78, p. 147-155 9 p.

    Research output: Contribution to journalArticle

  29. Shock index: An effective predictor of outcome in postpartum haemorrhage?

    Nathan, H. L., El Ayadi, A., Hezelgrave, N. L., Seed, P., Butrick, E., Miller, S., Briley, A., Bewley, S. & Shennan, A. H., 1 Jan 2015, In : BJOG: An International Journal of Obstetrics and Gynaecology. 122, 2, p. 268-275 8 p.

    Research output: Contribution to journalArticle

  30. Assessment of a Full Dilatation Cesarean Delivery Simulator

    Vousden, N., Hamakarim, Z., Briley, A., Girling, J., Seed, P. T., Tydeman, G. & Shennan, A. H., 2015, In : Obstetrics and Gynecology.

    Research output: Contribution to journalArticle

  31. Science forum: RIPOSTE: a framework for improving the design and analysis of laboratory-based research.

    Masca, N. G. D., Hensor, E. M. A., Cornelius, V. R., Buffa, F. M., Marriott, H. M., Eales, J. M., Messenger, M. P., Anderson, A. E., Boot, C., Bunce, C., Goldin, R. D., Harris, J., Hinchliffe, R. F., Junaid, H., Kingston, S., Martin-Ruiz, C., Nelson, C. P., Peacock, J., Seed, P. T., Shinkins, B. & 4 others, Staples, K. J., Toombs, J., Wright, A. K. A. & Teare, M. D., 2015, eLife. p. e05519 (eLife; vol. 4).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  32. 2014
  33. Benzo pyrene-induced DNA adducts and gene expression profiles in target and non-target organs for carcinogenesis in mice

    Zuo, J., Brewer, D. S., Arlt, V. M., Cooper, C. S. & Phillips, D. H., 8 Oct 2014, In : BMC GENOMICS. 15, 20 p., 880.

    Research output: Contribution to journalArticle

  34. AN INTERVENTION TRIAL FOR PEOPLE WITH EPILEPSY ATTENDING A&E

    Ridsdale, L. L., McCrone, P. R., Morgan, M. A., Seed, P., Goldstein, L. H. & Noble, A. J., 1 Oct 2014, In : Journal of Neurology, Neurosurgery and Psychiatry. 85, e4, p. A20 1 p., 075.

    Research output: Contribution to journalMeeting abstract

  35. Endocervical and high vaginal quantitative fetal fibronectin in predicting preterm birth

    Kuhrt, K., Unwin, C., Hezelgrave, N., Seed, P. & Shennan, A., 1 Oct 2014, In : JOURNAL OF MATERNAL FETAL AND NEONATAL MEDICINE. 27, 15, p. 1576-1579 4 p.

    Research output: Contribution to journalArticle

  36. The impact of rheumatoid arthritis on quality-of-life assessed using the SF-36: A systematic review and meta-analysis

    Matcham, F., Scott, I. C., Rayner, L., Hotopf, M., Kingsley, G. H., Norton, S., Scott, D. L. & Steer, S., 1 Oct 2014, In : Seminars in Arthritis and Rheumatism. 44, 2, p. 123-130 7 p.

    Research output: Contribution to journalArticle

  37. Mini-Mental State Examination as a Predictor of Mortality among Older People Referred to Secondary Mental Healthcare

    Su, Y-P., Chang, C-K., Hayes, R. D., Perera, G., Broadbent, M., To, D., Hotopf, M. & Stewart, R., 3 Sep 2014, In : PL o S One . 9, 9, 7 p., e105312.

    Research output: Contribution to journalArticle

  38. Prediction of gestational diabetes in obese pregnant women from the UK Pregnancies Better Eating and Activity (UPBEAT) pilot trial

    Maitland, R. A., Seed, P. T., Briley, A. L., Homsy, M., Thomas, S., Pasupathy, D., Robson, S. C., Nelson, S. M., Sattar, N., Poston, L. & UPBEAT Trial Consortium, Aug 2014, In : Diabetic Medicine. 31, 8, p. 963-970 8 p.

    Research output: Contribution to journalArticle

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