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Research Outputs

  1. 2015
  2. TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts

    Kucab, J. E., Zwart, E. P., van Steeg, H., Luijten, M., Schmeiser, H. H., Phillips, D. H. & Arlt, V. M., 8 Dec 2015, In : DNA REPAIR.

    Research output: Contribution to journalArticle

  3. A Randomized Trial of Progesterone in Women with Recurrent Miscarriages

    Coomarasamy, A., Williams, H., Truchanowicz, E., Seed, P. T., Small, R., Quenby, S., Gupta, P., Dawood, F., Koot, Y. E. M., Bender Atik, R., Bloemenkamp, K. W. M., Brady, R., Briley, A. L., Cavallaro, R., Cheong, Y. C., Chu, J. J., Eapen, A., Ewies, A., Hoek, A., Kaaijk, E. M. & 15 others, Koks, C. A. M., Li, T-C., MacLean, M., Mol, B. W., Moore, J., Ross, J. A., Sharpe, L., Stewart, J., Vaithilingam, N., Farquharson, R. G., Kilby, M. D., Khalaf, Y., Goddijn, M., Regan, L. & Rai, R., 26 Nov 2015, In : New England Journal of Medicine. 373, 22, p. 2141-8 8 p.

    Research output: Contribution to journalArticle

  4. The genome as a record of environmental exposure

    Nik-Zainal, S., Kucab, J. E., Morganella, S., Glodzik, D., Alexandrov, L. B., Arlt, V. M., Weninger, A., Hollstein, M., Stratton, M. R. & Phillips, D. H., Nov 2015, In : Mutagenesis. 30, 6, p. 763-770 8 p.

    Research output: Contribution to journalArticle

  5. The Brazilian 'Cracolândia' open drug scene and the challenge of implementing a comprehensive and effective drug policy

    Ribeiro, M., Duailibi, S., Frajzinger, R., Alonso, A. L. S., Marchetti, L., Williams, A. V., Strang, J. & Laranjeira, R., 26 Oct 2015, In : Addiction.

    Research output: Contribution to journalArticle

  6. Phenotypic heterogeneity in study populations may significantly confound the results of genetic association studies on alcohol dependence

    Ali, M. A., Way, M. J., Marks, M., Guerrini, I., Thomson, A. D., Strang, J., McQuillin, A. & Morgan, M. Y., 23 Oct 2015, In : Psychiatric Genetics. 25, 6, p. 234-240 7 p.

    Research output: Contribution to journalArticle

  7. Naloxone-does over-antagonism matter? Evidence of iatrogenic harm after emergency treatment of heroin/opioid overdose

    Neale, J. & Strang, J., 1 Oct 2015, In : Addiction. 110, 10, p. 1644-1652 9 p.

    Research output: Contribution to journalArticle

  8. Effect of a behavioural intervention in obese pregnant women (the UPBEAT study): a multicentre, randomised controlled trial

    Poston, L., Bell, R., Croker, H., Flynn, A. C., Godfrey, K. M., Goff, L., Hayes, L., Khazaezadeh, N., Nelson, S. M., Oteng-Ntim, E., Pasupathy, D., Patel, N., Robson, S. C., Sandall, J., Sanders, T. A. B., Sattar, N., Seed, P. T., Wardle, J., Whitworth, M. K., Briley, A. L. & 1 others, UPBEAT Trial Consortium, Oct 2015, In : The Lancet Diabetes and Endocrinology. 3, 10, p. 767-777 11 p.

    Research output: Contribution to journalArticle

  9. Heroin overdose resuscitation with naloxone: Patient uses own prescribed supply to save the life of a peer

    Winston, I., McDonald, R., Tas, B. & Strang, J., 14 Sep 2015, In : BMJ case reports. 2015, 210391.

    Research output: Contribution to journalArticle

  10. Drug-related mortality in psychiatric patients

    Lynskey, M. T., Kimber, J. & Strang, J., 1 Sep 2015, In : The Lancet Psychiatry. 2, 9, p. 767-769 3 p.

    Research output: Contribution to journalArticle

  11. Prenatal exposure to polycyclic aromatic hydrocarbons/aromatics, BDNF and child development

    Perera, F., Phillips, D. H., Wang, Y., Roen, E., Herbstman, J., Rauh, V., Wang, S. & Tang, D., 21 Aug 2015, In : Environmental Research. 142, p. 602-608 7 p., 6575.

    Research output: Contribution to journalArticle

  12. Diagnostic accuracy of placental growth factor and ultrasound parameters to predict the small-for-gestational-age infant in women presenting with reduced symphysis-fundus height

    Griffin, M., Seed, P. T., Webster, L., Myers, J., Mackillop, L., Simpson, N., Anumba, D., Khalil, A., Denbow, M., Sau, A., Hinshaw, K., Von Dadelszen, P., Benton, S., Girling, J., Redman, C. W. G., Chappell, L. C. & Shennan, A. H., 1 Aug 2015, In : Ultrasound in Obstetrics and Gynecology. 46, 2, p. 182-190 9 p.

    Research output: Contribution to journalArticle

  13. The association between speed of transition from initiation to subsequent use of cannabis and later problematic cannabis use, abuse and dependence

    Hines, L. A., Morley, K. I., Strang, J., Agrawal, A., Nelson, E. C., Statham, D., Martin, N. G. & Lynskey, M. T., 1 Aug 2015, In : Addiction. 110, 8, p. 1311-1320 10 p.

    Research output: Contribution to journalArticle

  14. Death matters: Understanding heroin/opiate overdose risk and testing potential to prevent deaths

    Strang, J., 1 Jul 2015, In : Addiction. 110, S2, p. 27-35 9 p.

    Research output: Contribution to journalArticle

  15. Griffith Edwards, the Addiction Research Unit and research on the criminal justice system

    Farrell, M., Marsden, J. & Strang, J., 1 Jul 2015, In : Addiction. 110, S2, p. 54-58 5 p.

    Research output: Contribution to journalArticle

  16. Heroin on trial: Systematic review and meta-analysis of randomised trials of diamorphine-prescribing as treatment for refractory heroin addiction

    Strang, J., Groshkova, T., Uchtenhagen, A., Van Den Brink, W., Haasen, C., Schechter, M. T., Lintzeris, N., Bell, J., Pirona, A., Oviedo-Joekes, E., Simon, R. & Metrebian, N., 1 Jul 2015, In : British Journal of Psychiatry. 207, 1, p. 5-14 10 p.

    Research output: Contribution to journalArticle

  17. A mismatch between population health literacy and the complexity of health information: An observational study

    Rowlands, G., Protheroe, J., Winkley, J., Richardson, M., Seed, P. T. & Rudd, R., 1 Jun 2015, In : The British journal of general practice : the journal of the Royal College of General Practitioners. 65, 635, p. 379-386 8 p.

    Research output: Contribution to journalArticle

  18. Adverse maternal and perinatal outcomes in pregnant women with sickle cell disease: Systematic review and meta-analysis

    Oteng-Ntim, E., Meeks, D., Seed, P. T., Webster, L., Howard, J., Doyle, P. & Chappell, L. C., 21 May 2015, In : Blood. 125, 21, p. 3316-3325 10 p.

    Research output: Contribution to journalArticle

  19. RIPOSTE: A framework for improving the design and analysis of laboratory-based research

    Masca, N. G. D., Hensor, E. M. A., Cornelius, V., Buffa, F. M., Marriott, H. M., Eales, J. M., Messenger, M. P., Anderson, A. E., Boot, C., Bunce, C., Goldin, R. D., Harris, J., Hinchliffe, R. F., Junaid, H., Kingston, S., Martin-Ruiz, C., Nelson, C. P., Peacock, J., Seed, P. T., Shinkins, B. & 4 others, Staples, K. J., Toombs, J., Wright, A. K. A. & Dawn Teare, M., 7 May 2015, In : eLife. 4, p. 1-27 27 p.

    Research output: Contribution to journalArticle

  20. Quantitative fetal fibronectin to predict preterm birth in asymptomatic women at high risk

    Abbott, D. S., Hezelgrave, N. L., Seed, P. T., Norman, J. E., David, A. L., Bennett, P. R., Girling, J. C., Chandirimani, M., Stock, S. J., Carter, J., Cate, R., Kurtzman, J., Tribe, R. M. & Shennan, A. H., 1 May 2015, In : Obstetrics and Gynecology. 125, 5, p. 1168-1176 9 p.

    Research output: Contribution to journalArticle

  21. The Hepatic Reductase Null (HRN™) and Reductase Conditional Null (RCN) mouse models as suitable tools to study metabolism, toxicity and carcinogenicity of environmental pollutants

    Arlt, V. M., Henderson, C. J., Wolf, C. R., Stiborova, M. & Phillips, D. H., 1 May 2015, In : Toxicology Research. 4, 3, p. 548-562 15 p.

    Research output: Contribution to journalLiterature review

  22. Pulmonary inflammation impacts on CYP1A1-mediated respiratory tract DNA damage induced by the carcinogenic air pollutant benzo[a]pyrene

    Arlt, V. M., Krais, A., Godschalk, R. W., Riffo-Vasquez, Y., Mrizova, I., Roufosse, C. A., Corbin, C., Shi, Q., Frei, E., Stiborova, M., van Schooten, F-J., Phillips, D. H. & Spina, D., 23 Apr 2015, In : Toxicological sciences : an official journal of the Society of Toxicology. 146, 2, p. 213-225 13 p.

    Research output: Contribution to journalArticle

  23. TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts

    Kucab, J. E., van Steeg, H., Luijten, M., Schmeiser, H. H., White, P. A., Phillips, D. H. & Arlt, V. M., 1 Mar 2015, In : Mutation Research. 773, p. 48-62 15 p.

    Research output: Contribution to journalArticle

  24. Dalteparin for pregnant women with thrombophilia

    Hunt, B. J., Seed, P. T. & Lefkou, E., 21 Feb 2015, In : Lancet. 385, 9969, p. 689 1 p.

    Research output: Contribution to journalLiterature review

  25. Endothelial and platelet microparticles in patients with antiphospholipid antibodies

    Breen, K. A., Sanchez, K., Kirkman, N., Seed, P. T., Parmar, K., Moore, G. W. & Hunt, B. J., 1 Feb 2015, In : Thrombosis Research. 135, 2, p. 368-374 7 p.

    Research output: Contribution to journalArticle

  26. Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts

    Krais, A. M., Mühlbauer, K-R., Kucab, J. E., Chinbuah, H., Cornelius, M. G., Wei, Q-X., Hollstein, M., Phillips, D. H., Arlt, V. M. & Schmeiser, H. H., Feb 2015, In : Toxicology in Vitro. 29, 1, p. 34-43 10 p.

    Research output: Contribution to journalArticle

  27. Hepatitis B vaccination for people who inject drugs--authors' reply

    Weaver, T., Metrebian, N. & Strang, J., 10 Jan 2015, In : Lancet. 385, 9963, p. 116-116 1 p.

    Research output: Contribution to journalArticle

  28. Association between maternal micronutrient status, oxidative stress and common genetic variants in antioxidant enzymes at 15 weeks' gestation in nulliparous women who subsequently develop pre-eclampsia

    Mistry, H. D., Gill, C. A., Kurlak, L. O., Seed, P. T., Hesketh, J. E., Méplan, C., Schomburg, L., Chappell, L. C., Morgan, L., Poston, L. & on behalf of SCOPE consortium, 1 Jan 2015, In : Free Radical Biology and Medicine. 78, p. 147-155 9 p.

    Research output: Contribution to journalArticle

  29. Mobile phone ownership, usage and readiness to use by patients in drug treatment

    Milward, J., Day, E., Wadsworth, E., Strang, J. & Lynskey, M., 1 Jan 2015, In : Drug and Alcohol Dependence. 146, p. 111-115 5 p.

    Research output: Contribution to journalArticle

  30. Shock index: An effective predictor of outcome in postpartum haemorrhage?

    Nathan, H. L., El Ayadi, A., Hezelgrave, N. L., Seed, P., Butrick, E., Miller, S., Briley, A., Bewley, S. & Shennan, A. H., 1 Jan 2015, In : BJOG: An International Journal of Obstetrics and Gynaecology. 122, 2, p. 268-275 8 p.

    Research output: Contribution to journalArticle

  31. Assessment of a Full Dilatation Cesarean Delivery Simulator

    Vousden, N., Hamakarim, Z., Briley, A., Girling, J., Seed, P. T., Tydeman, G. & Shennan, A. H., 2015, In : Obstetrics and Gynecology.

    Research output: Contribution to journalArticle

  32. Evaluation of Femoral Ultrasonography as a Tool for Promoting Cessation of Groin-Injecting Behaviour

    Senbanjo, R. & Strang, J., 2015, In : European Addiction Research. 21, 4, p. 204-210 7 p.

    Research output: Contribution to journalArticle

  33. Linked randomised controlled trials of face-to-face and electronic brief intervention methods to prevent alcohol related harm in young people aged 14-17 years presenting to Emergency Departments (SIPS junior)

    Deluca, P., Coulton, S., Alam, M. F., Cohen, D., Donoghue, K., Gilvarry, E., Kaner, E., Maconochie, I., McArdle, P., McGovern, R., Newbury-Birch, D., Patton, R., Phillips, C., Phillips, T., Russell, I., Strang, J. & Drummond, C., 2015, In : BMC Public Health. 15, p. 1-8 345.

    Research output: Contribution to journalArticle

  34. Safety and tolerability of as-needed nalmefene in the treatment of alcohol dependence: results from the Phase III clinical programme

    van den Brink, W., Strang, J., Gual, A., Sørensen, P., Jensen, T. J. & Mann, K., 2015, In : Expert Opinion On Drug Safety. p. 1-10 10 p.

    Research output: Contribution to journalArticle

  35. Science forum: RIPOSTE: a framework for improving the design and analysis of laboratory-based research.

    Masca, N. G. D., Hensor, E. M. A., Cornelius, V. R., Buffa, F. M., Marriott, H. M., Eales, J. M., Messenger, M. P., Anderson, A. E., Boot, C., Bunce, C., Goldin, R. D., Harris, J., Hinchliffe, R. F., Junaid, H., Kingston, S., Martin-Ruiz, C., Nelson, C. P., Peacock, J., Seed, P. T., Shinkins, B. & 4 others, Staples, K. J., Toombs, J., Wright, A. K. A. & Teare, M. D., 2015, eLife. p. e05519 (eLife; vol. 4).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  36. 2014
  37. What would an evidence based drug policy be like?

    Singleton, N. & Strang, J., 9 Dec 2014, In : BMJ (Clinical research ed.). 349, 2 p., g7493.

    Research output: Contribution to journalEditorial

  38. Take-home emergency naloxone to prevent deaths from heroin overdose

    Strang, J., Bird, S. M., Dietze, P., Gerra, G. & McLellan, A. T., 4 Nov 2014, In : BMJ (Clinical research ed.). 349, 2 p., g6580.

    Research output: Contribution to journalArticle

  39. Alcohol Harm Reduction: Corporate Capture of a Key Concept

    McCambridge, J., Kypri, K., Drummond, C. & Strang, J., 9 Oct 2014, In : PL o S Medicine. 11, 12, e1001767.

    Research output: Contribution to journalArticle

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