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Research Outputs

  1. 2015
  2. Identification and validation of biomarkers for autism spectrum disorders

    Loth, E., Spooren, W., Ham, L. M., Isaac, M. B., Auriche-Benichou, C., Banaschewski, T., Baron-Cohen, S., Broich, K., Bölte, S., Bourgeron, T., Charman, T., Collier, D., de Andres-Trelles, F., Durston, S., Ecker, C., Elferink, A., Haberkamp, M., Hemmings, R., Johnson, M. H., Jones, E. J. H. & 18 others, Khwaja, O. S., Lenton, S., Mason, L., Mantua, V., Meyer-Lindenberg, A., Lombardo, M. V., O'Dwyer, L., Okamoto, K., Pandina, G. J., Pani, L., Persico, A. M., Simonoff, E., Tauscher-Wisniewski, S., Llinares-Garcia, J., Vamvakas, S., Williams, S., Buitelaar, J. K. & Murphy, D. G. M., 31 Dec 2015, In : Nature Reviews Drug Discovery. 15, 1, p. 70-73 4 p.

    Research output: Contribution to journalArticle

  3. TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts

    Kucab, J. E., Zwart, E. P., van Steeg, H., Luijten, M., Schmeiser, H. H., Phillips, D. H. & Arlt, V. M., 8 Dec 2015, In : DNA REPAIR.

    Research output: Contribution to journalArticle

  4. Neuroimaging in autism spectrum disorder: Brain structure and function across the lifespan

    Ecker, C., Bookheimer, S. Y. & Murphy, D. G. M., 1 Nov 2015, In : Lancet Neurology. 14, 11, p. 1121-1134 14 p., 147.

    Research output: Contribution to journalArticle

  5. The genome as a record of environmental exposure

    Nik-Zainal, S., Kucab, J. E., Morganella, S., Glodzik, D., Alexandrov, L. B., Arlt, V. M., Weninger, A., Hollstein, M., Stratton, M. R. & Phillips, D. H., Nov 2015, In : Mutagenesis. 30, 6, p. 763-770 8 p.

    Research output: Contribution to journalArticle

  6. Family therapy for autism spectrum disorders

    Spain, D. C., Sin, P. H. J., Paliokostas, E., Furuta, M., Chalder, T., Murphy, D. G. & Happe, F. G. E., 11 Oct 2015, In : Cochrane database of systematic reviews (Online). 10CD011894

    Research output: Contribution to journalArticle

  7. Neuroanatomy of individual differences in language in adult males with autism

    Lai, M. C., Lombardo, M. V., Ecker, C., Chakrabarti, B., Suckling, J., Bullmore, E. T., Happé, F., Murphy, D. G. M. & Baron-Cohen, S., 1 Oct 2015, In : Cerebral Cortex. 25, 10, p. 3613-3628 16 p.

    Research output: Contribution to journalArticle

  8. Relationship between surface-based brain morphometric measures and intelligence in autism spectrum disorders: Influence of history of language delay

    Balardin, J. B., Sato, J. R., Vieira, G., Feng, Y., Daly, E., Murphy, C., Murphy, D., Ecker, C. & MRC AIMS consortium, 1 Oct 2015, In : Autism research. 8, 5, p. 556-566 11 p.

    Research output: Contribution to journalArticle

  9. Decreased centrality of cortical volume covariance networks in autism spectrum disorders

    Balardin, J. B., Comfort, W. E., Daly, E., Murphy, C., Andrews, D., Murphy, D. G. M., Ecker, C., MRC AIMS consortium & Sato, J. R., Oct 2015, In : Journal of psychiatric research. 69, p. 142-149 8 p.

    Research output: Contribution to journalArticle

  10. Prenatal exposure to polycyclic aromatic hydrocarbons/aromatics, BDNF and child development

    Perera, F., Phillips, D. H., Wang, Y., Roen, E., Herbstman, J., Rauh, V., Wang, S. & Tang, D., 21 Aug 2015, In : Environmental Research. 142, p. 602-608 7 p., 6575.

    Research output: Contribution to journalArticle

  11. Episodic Recollection Difficulties in ASD Result from Atypical Relational Encoding: Behavioral and Neural Evidence

    Gaigg, S. B., Bowler, D. M., Ecker, C., Calvo-Merino, B. & Murphy, D. G., 1 Jun 2015, In : Autism research. 8, 3, p. 317-327 11 p.

    Research output: Contribution to journalArticle

  12. The Hepatic Reductase Null (HRN™) and Reductase Conditional Null (RCN) mouse models as suitable tools to study metabolism, toxicity and carcinogenicity of environmental pollutants

    Arlt, V. M., Henderson, C. J., Wolf, C. R., Stiborova, M. & Phillips, D. H., 1 May 2015, In : Toxicology Research. 4, 3, p. 548-562 15 p.

    Research output: Contribution to journalLiterature review

  13. Pulmonary inflammation impacts on CYP1A1-mediated respiratory tract DNA damage induced by the carcinogenic air pollutant benzo[a]pyrene

    Arlt, V. M., Krais, A., Godschalk, R. W., Riffo-Vasquez, Y., Mrizova, I., Roufosse, C. A., Corbin, C., Shi, Q., Frei, E., Stiborova, M., van Schooten, F-J., Phillips, D. H. & Spina, D., 23 Apr 2015, In : Toxicological sciences : an official journal of the Society of Toxicology. 146, 2, p. 213-225 13 p.

    Research output: Contribution to journalArticle

  14. Cognitive decline preceding the onset of psychosis in patients with 22q11.2 deletion syndrome

    Vorstman, J. A. S., Breetvelt, E. J., Duijff, S. N., Eliez, S., Schneider, M., Jalbrzikowski, M., Armando, M., Vicari, S., Shashi, V., Hooper, S. R., Chow, E. W. C., Fung, W. L. A., Butcher, N. J., Young, D. A., McDonald-McGinn, D. M., Vogels, A., Van Amelsvoort, T., Gothelf, D., Weinberger, R., Weizman, A. & 33 others, Klaassen, P. W. J., Koops, S., Kates, W. R., Antshel, K. M., Simon, T. J., Ousley, O. Y., Swillen, A., Gur, R. E., Bearden, C. E., Kahn, R. S., Bassett, A. S., Emanuel, B. S., Zackai, E. H., Kushan, L., Fremont, W., Schoch, K., Stoddard, J., Cubells, J., Fu, F., Campbell, L. E., Fritsch, R., Vergaelen, E., Neeleman, M., Boot, E., Debbané, M., Philip, N., Green, T., Van DenBree, M. B. M., Murphy, D., Canyelles, J. M., Arango, C., Murphy, K. C. & Pontillo, M., 1 Apr 2015, In : JAMA Psychiatry. 72, 4, p. 377-385 9 p.

    Research output: Contribution to journalArticle

  15. White-matter relaxation time and myelin water fraction differences in young adults with autism

    Zinkstok, J. R., Daly, E., Ecker, C., Williams, S. C. R., Murphy, D. G. M., Bailey, A. J., Baron-Cohen, S., Bolton, P. F., Bullmore, E. T., Carrington, S., Chakrabarti, B., Daly, E. M., Deoni, S. C. L., Ecker, C., Happe, F., Henty, J., Jezzard, P., Johnston, P., Jones, D. K., Lombardo, M. V. & 11 others, Madden, A., Mullins, D., Murphy, C., Murphy, D. G., Pasco, G., Sadek, S. A., Spain, D., Steward, R., Suckling, J., Wheelwright, S. & Williams, S., 12 Mar 2015, In : Psychological Medicine. 45, 4, p. 795-805 11 p.

    Research output: Contribution to journalArticle

  16. TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts

    Kucab, J. E., van Steeg, H., Luijten, M., Schmeiser, H. H., White, P. A., Phillips, D. H. & Arlt, V. M., 1 Mar 2015, In : Mutation Research. 773, p. 48-62 15 p.

    Research output: Contribution to journalArticle

  17. Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts

    Krais, A. M., Mühlbauer, K-R., Kucab, J. E., Chinbuah, H., Cornelius, M. G., Wei, Q-X., Hollstein, M., Phillips, D. H., Arlt, V. M. & Schmeiser, H. H., Feb 2015, In : Toxicology in Vitro. 29, 1, p. 34-43 10 p.

    Research output: Contribution to journalArticle

  18. Emotional detachment in psychopathy: Involvement of dorsal default-mode connections

    Arjun, S., Gregory, S. L., Dell' Acqua, F., Thomas, E., Simmons, A., Murphy, D. G., Hodgins, S. M., Blackwood, N. & Craig, M. C., Jan 2015, In : Cortex. 62, p. 11-19 9 p.

    Research output: Contribution to journalArticle

  19. GABA(A) Receptors in Autism - a Multicenter Positron Emission Tomography Study

    Mendez Hernandez, M. A., Borg, J., Horder, J., Veronese, M., Lundberg, J., Myers, J., Andersson, M., Mick, I., Tangen, A., Farde, L., Halldin, C., Selvaraj, S., Lingford-Hughes, A., Howes, O. D., Nutt, D. J. & Murphy, D. G., 2015, 14th International Meeting for Autism Research (IMFAR), 2015.

    Research output: Chapter in Book/Report/Conference proceedingMeeting abstract

  20. 2014
  21. European clinical network: autism spectrum disorder assessments and patient characterisation

    Ashwood, K. L., Buitelaar, J., Murphy, D., Spooren, W. & Charman, T., 4 Dec 2014, In : European Child and Adolescent Psychiatry. 24, 8, p. 985-995 11 p.

    Research output: Contribution to journalArticle

  22. Public-private partnership: A new engine for translational research in neurosciences

    Murphy, D. G. M., Goldman, M., Loth, E. & Spooren, W., 5 Nov 2014, In : Neuron. 84, 3, p. 533-536 4 p.

    Research output: Contribution to journalArticle

  23. New treatment targets for autism spectrum disorders: EU-AIMS

    Loth, E., Spooren, W. & Murphy, D. G., 1 Nov 2014, In : The Lancet Psychiatry. 1, 6, p. 413-415 3 p.

    Research output: Contribution to journalArticle

  24. Benzo pyrene-induced DNA adducts and gene expression profiles in target and non-target organs for carcinogenesis in mice

    Zuo, J., Brewer, D. S., Arlt, V. M., Cooper, C. S. & Phillips, D. H., 8 Oct 2014, In : BMC GENOMICS. 15, 20 p., 880.

    Research output: Contribution to journalArticle

  25. Coregistering functional near-infrared spectroscopy with underlying cortical areas in infants

    Lloyd-Fox, S., Richards, J. E., Blasi, A., Murphy, D. G. M., Elwell, C. E. & Johnson, M. H., 1 Oct 2014, In : Neurophotonics. 1, 2, 14007RR.

    Research output: Contribution to journalArticle

  26. Response inhibition and serotonin in autism: a functional MRI study using acute tryptophan depletion

    Daly, E., Ecker, C., Hallahan, B., Deeley, Q., Craig, M., Murphy, C., Johnston, P., Spain, D., Gillan, N., Gudbrandsen, M., Brammer, M., Giampietro, V., Lamar, M., Page, L., Toal, F., Schmitz, N., Cleare, A., Robertson, D., Rubia, K. & Murphy, D. G. M., 1 Sep 2014, In : Brain. 137, 9, p. 2600-2610 11 p.

    Research output: Contribution to journalArticle

  27. Are power calculations useful? A multicentre neuroimaging study

    Suckling, J., Henty, J., Ecker, C., Deoni, S. C., Lombardo, M. V., Baron-Cohen, S., Jezzard, P., Barnes, A., Chakrabarti, B., Ooi, C., Lai, M-C., Williams, S. C., Murphy, D. G. M., Bullmore, E. & for the MRC AIMS Consortium, Aug 2014, In : Human Brain Mapping. 35, 8, p. 3569-3577 9 p.

    Research output: Contribution to journalArticle

  28. Exceptionally long-term persistence of DNA adducts formed by carcinogenic aristolochic acid I in renal tissue from patients with aristolochic acid nephropathy

    Schmeiser, H. H., Nortier, J. L., Singh, R., da Costa, G. G., Sennesael, J., Cassuto-Viguier, E., Ambrosetti, D., Rorive, S., Pozdzik, A., Phillips, D. H., Stiborova, M. & Arlt, V. M., 15 Jul 2014, In : International Journal of Cancer. 135, 2, p. 502-507 6 p.

    Research output: Contribution to journalArticle

  29. Variation of DNA damage levels in peripheral blood mononuclear cells isolated in different laboratories

    Godschalk, R. W. L., Ersson, C., Stępnik, M., Ferliłska, M., Palus, J., Teixeira, J. P., Costa, S., Jones, G. D. D., Higgins, J. A., Kain, J., Möller, L., Forchhammer, L., Loft, S., Lorenzo, Y., Collins, A. R., van Schooten, F-J., Laffon, B., Valdiglesias, V., Cooke, M., Mistry, V. & 12 others, Karbaschi, M., Phillips, D. H., Sozeri, O., Routledge, M. N., Nelson-Smith, K., Riso, P., Porrini, M., López de Cerain, A., Azqueta, A., Matullo, G., Allione, A. & Møller, P., Jul 2014, In : Mutagenesis. 29, 4, p. 241-249 9 p.

    Research output: Contribution to journalArticle

  30. MGMT promoter hypermethylation and K-RAS, PTEN and TP53 mutations in tamoxifen-exposed and non-exposed endometrial cancer cases

    Nagy, E., Gajjar, K. B., Patel, I. I., Taylor, S., Martin-Hirsch, P. L., Stringfellow, H. F., Martin, F. L. & Phillips, D. H., 10 Jun 2014, In : BJC: British Journal of Cancer. 110, 12, p. 2874-2880 7 p.

    Research output: Contribution to journalArticle

  31. Psychiatric Disorders From Childhood to Adulthood in 22q11.2 Deletion Syndrome: Results From the International Consortium on Brain and Behavior in 22q11.2 Deletion Syndrome

    Schneider, M., Debbane, M., Bassett, A. S., Chow, E. W. C., Fung, W. L. A., van den Bree, M. B. M., Owen, M., Murphy, K. C., Niarchou, M., Kates, W. R., Antshel, K. M., Fremont, W., McDonald-McGinn, D. M., Gur, R. E., Zackai, E. H., Vorstman, J., Duijff, S. N., Klaassen, P. W. J., Swillen, A., Gothelf, D. & 17 others, Green, T., Weizman, A., Van Amelsvoort, T., Evers, L., Boot, E., Shashi, V., Hooper, S. R., Bearden, C. E., Jalbrzikowski, M., Armando, M., Vicari, S., Murphy, D. G., Ousley, O., Campbell, L. E., Simon, T. J., Eliez, S. & Int Consortium Brain Behav 22q11 2, Jun 2014, In : The American Journal of Psychiatry. 171, 6, p. 627-639 13 p.

    Research output: Contribution to journalLiterature review

  32. Cytochronne b(5) and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions

    Stiborová, M., Moserová, M., Cerná, V., Indra, R., Dračínský, M., Sulc, M., Henderson, C. J., Wolf, C. R., Schmeiser, H. H., Phillips, D. H., Frei, E. & Arlt, V. M., 6 Apr 2014, In : Toxicology. 318, p. 1-12 12 p.

    Research output: Contribution to journalArticle

  33. Glutamate/glutamine and neuronal integrity in adults with ADHD: A proton MRS study

    Maltezos, S., Horder, J., Coghlan, S., Skirrow, C., O'Gorman, R., Lavender, T. J., Mendez, M. A., Mehta, M., Daly, E., Xenitidis, K., Paliokosta, E., Spain, D., Pitts, M., Asherson, P., Lythgoe, D. J., Barker, G. J. & Murphy, D. G., 18 Mar 2014, In : Translational psychiatry. 4, e373.

    Research output: Contribution to journalArticle

  34. Autism spectrum disorders - An emerging area in psychopharmacology

    Steckler, T., Spooren, W. & Murphy, D., Mar 2014, In : Psychopharmacology. 231, 6, p. 977-978 2 p.

    Research output: Contribution to journalArticle

  35. Psychopharmacological prescriptions for people with autism spectrum disorder (ASD): a multinational study

    Hsia, Y., Wong, A. Y. S., Murphy, D. G. M., Simonoff, E., Buitelaar, J. K. & Wong, I. C. K., Mar 2014, In : Psychopharmacology. 231, 6, p. 999-1009 11 p., N/A.

    Research output: Contribution to journalArticle

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