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Research Outputs

  1. 2015
  2. Prognostic and mechanistic potential of progesterone sulfates in intrahepatic cholestasis of pregnancy and pruritus gravidarum

    Abu-Hayyeh, S., Ovadia, C., Lieu, T., Jensen, D. D., Chambers, J., Dixon, P. H., Lövgren-Sandblom, A., Bolier, R., Tolenaars, D., Kremer, A. E., Syngelaki, A., Noori, M., Williams, D., Marin, J. J. G., Monte, M. J., Nicolaides, K. H., Beuers, U., Oude-Elferink, R., Seed, P. T., Chappell, L. & 3 others, Marschall, H-U., Bunnett, N. W. & Williamson, C., 28 Dec 2015, In : Hepatology.

    Research output: Contribution to journalArticle

  3. The NADPH oxidase Nox4 has anti-atherosclerotic functions

    Schürmann, C., Rezende, F., Kruse, C., Yasar, Y., Löwe, O., Fork, C., Van De Sluis, B., Bremer, R., Weissmann, N., Shah, A. M., Jo, H., Brandes, R. P. & Schröder, K., 21 Dec 2015, In : European Heart Journal. 36, 48, p. 3447-3456 10 p.

    Research output: Contribution to journalArticle

  4. NADPH oxidase 4 regulates homocysteine metabolism and protects against acetaminophen-induced liver damage in mice

    Murray, T. V. A., Dong, X., Sawyer, G. J., Caldwell, A., Halket, J., Sherwood, R., Quaglia, A., Dew, T., Anilkumar, N., Burr, S., Mistry, R. K., Martin, D., Schröder, K., Brandes, R. P., Hughes, R. D., Shah, A. M. & Brewer, A. C., 1 Dec 2015, In : Free Radical Biology and Medicine. 89, p. 918-930 13 p.

    Research output: Contribution to journalArticle

  5. A Randomized Trial of Progesterone in Women with Recurrent Miscarriages

    Coomarasamy, A., Williams, H., Truchanowicz, E., Seed, P. T., Small, R., Quenby, S., Gupta, P., Dawood, F., Koot, Y. E. M., Bender Atik, R., Bloemenkamp, K. W. M., Brady, R., Briley, A. L., Cavallaro, R., Cheong, Y. C., Chu, J. J., Eapen, A., Ewies, A., Hoek, A., Kaaijk, E. M. & 15 others, Koks, C. A. M., Li, T-C., MacLean, M., Mol, B. W., Moore, J., Ross, J. A., Sharpe, L., Stewart, J., Vaithilingam, N., Farquharson, R. G., Kilby, M. D., Khalaf, Y., Goddijn, M., Regan, L. & Rai, R., 26 Nov 2015, In : New England Journal of Medicine. 373, 22, p. 2141-8 8 p.

    Research output: Contribution to journalArticle

  6. Effect of a behavioural intervention in obese pregnant women (the UPBEAT study): a multicentre, randomised controlled trial

    Poston, L., Bell, R., Croker, H., Flynn, A. C., Godfrey, K. M., Goff, L., Hayes, L., Khazaezadeh, N., Nelson, S. M., Oteng-Ntim, E., Pasupathy, D., Patel, N., Robson, S. C., Sandall, J., Sanders, T. A. B., Sattar, N., Seed, P. T., Wardle, J., Whitworth, M. K., Briley, A. L. & 1 others, UPBEAT Trial Consortium, 1 Oct 2015, In : The Lancet Diabetes and Endocrinology. 3, 10, p. 767-777 11 p.

    Research output: Contribution to journalArticle

  7. Deficient angiogenesis in redox-dead Cys17Ser PKARIα knock-in mice

    Burgoyne, J., Rudyk, O., Cho, H. J., Prysyazhna, O., Hathaway, N., Weeks, A., Evans, R., Ng, T., Schröder, K., Brandes, R. P., Shah, A. M. & Eaton, P., 10 Aug 2015, In : Nature Communications. 6, 7920.

    Research output: Contribution to journalArticle

  8. Diagnostic accuracy of placental growth factor and ultrasound parameters to predict the small-for-gestational-age infant in women presenting with reduced symphysis-fundus height

    Griffin, M., Seed, P. T., Webster, L., Myers, J., Mackillop, L., Simpson, N., Anumba, D., Khalil, A., Denbow, M., Sau, A., Hinshaw, K., Von Dadelszen, P., Benton, S., Girling, J., Redman, C. W. G., Chappell, L. C. & Shennan, A. H., 1 Aug 2015, In : Ultrasound in Obstetrics and Gynecology. 46, 2, p. 182-190 9 p.

    Research output: Contribution to journalArticle

  9. Contractile Function during Angiotensin-II Activation: Increased Nox2 Activity Modulates Cardiac Calcium Handling via Phospholamban Phosphorylation

    Zhang, M., Prosser, B. L., Bamboye, M. A., Gondim, A. N. S., Santos, C. X., Martin, D., Ghigo, A., Perino, A., Brewer, A. C., Ward, C. W., Hirsch, E., Lederer, W. J. & Shah, A. M., 21 Jul 2015, In : Journal of the American College of Cardiology. 66, 3, p. 261-272 12 p.

    Research output: Contribution to journalArticle

  10. Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation

    Murakawa, T., Yamaguchi, O., Hashimoto, A., Hikoso, S., Takeda, T., Oka, T., Yasui, H., Ueda, H., Akazawa, Y., Nakayama, H., Taneike, M., Misaka, T., Omiya, S., Shah, A. M., Yamamoto, A., Nishida, K., Ohsumi, Y., Okamoto, K., Sakata, Y. & Otsu, K., 6 Jul 2015, In : Nature Communications. 6, p. 7527 1 p.

    Research output: Contribution to journalArticle

  11. A mismatch between population health literacy and the complexity of health information: An observational study

    Rowlands, G., Protheroe, J., Winkley, J., Richardson, M., Seed, P. T. & Rudd, R., 1 Jun 2015, In : The British journal of general practice : the journal of the Royal College of General Practitioners. 65, 635, p. 379-386 8 p.

    Research output: Contribution to journalArticle

  12. Adverse maternal and perinatal outcomes in pregnant women with sickle cell disease: Systematic review and meta-analysis

    Oteng-Ntim, E., Meeks, D., Seed, P. T., Webster, L., Howard, J., Doyle, P. & Chappell, L. C., 21 May 2015, In : Blood. 125, 21, p. 3316-3325 10 p.

    Research output: Contribution to journalArticle

  13. RIPOSTE: A framework for improving the design and analysis of laboratory-based research

    Masca, N. G. D., Hensor, E. M. A., Cornelius, V., Buffa, F. M., Marriott, H. M., Eales, J. M., Messenger, M. P., Anderson, A. E., Boot, C., Bunce, C., Goldin, R. D., Harris, J., Hinchliffe, R. F., Junaid, H., Kingston, S., Martin-Ruiz, C., Nelson, C. P., Peacock, J., Seed, P. T., Shinkins, B. & 4 others, Staples, K. J., Toombs, J., Wright, A. K. A. & Dawn Teare, M., 7 May 2015, In : eLife. 4, p. 1-27 27 p.

    Research output: Contribution to journalArticle

  14. Quantitative fetal fibronectin to predict preterm birth in asymptomatic women at high risk

    Abbott, D. S., Hezelgrave, N. L., Seed, P. T., Norman, J. E., David, A. L., Bennett, P. R., Girling, J. C., Chandirimani, M., Stock, S. J., Carter, J., Cate, R., Kurtzman, J., Tribe, R. M. & Shennan, A. H., 1 May 2015, In : Obstetrics and Gynecology. 125, 5, p. 1168-1176 9 p.

    Research output: Contribution to journalArticle

  15. Cardiac-targeted NADPH oxidase 4 in the adaptive cardiac remodelling of the murine heart

    Nabeebaccus, A., Hafstad, A., Eykyn, T., Yin, X., Brewer, A., Zhang, M., Mayr, M. & Shah, A., 26 Feb 2015, In : Lancet. 385 Suppl 1, p. S73

    Research output: Contribution to journalArticle

  16. Dalteparin for pregnant women with thrombophilia

    Hunt, B. J., Seed, P. T. & Lefkou, E., 21 Feb 2015, In : Lancet. 385, 9969, p. 689 1 p.

    Research output: Contribution to journalLiterature review

  17. Endothelial and platelet microparticles in patients with antiphospholipid antibodies

    Breen, K. A., Sanchez, K., Kirkman, N., Seed, P. T., Parmar, K., Moore, G. W. & Hunt, B. J., 1 Feb 2015, In : Thrombosis Research. 135, 2, p. 368-374 7 p.

    Research output: Contribution to journalArticle

  18. Heart failure: Mitochondrial dysfunction and oxidative stress in CHF

    Okonko, D. O. & Shah, A. M., 11 Jan 2015, In : Nature Reviews Cardiology. 12, 1, p. 6-8 3 p.

    Research output: Contribution to journalArticle

  19. Association between maternal micronutrient status, oxidative stress and common genetic variants in antioxidant enzymes at 15 weeks' gestation in nulliparous women who subsequently develop pre-eclampsia

    Mistry, H. D., Gill, C. A., Kurlak, L. O., Seed, P. T., Hesketh, J. E., Méplan, C., Schomburg, L., Chappell, L. C., Morgan, L., Poston, L. & on behalf of SCOPE consortium, 1 Jan 2015, In : Free Radical Biology and Medicine. 78, p. 147-155 9 p.

    Research output: Contribution to journalArticle

  20. Shock index: An effective predictor of outcome in postpartum haemorrhage?

    Nathan, H. L., El Ayadi, A., Hezelgrave, N. L., Seed, P., Butrick, E., Miller, S., Briley, A., Bewley, S. & Shennan, A. H., 1 Jan 2015, In : BJOG: An International Journal of Obstetrics and Gynaecology. 122, 2, p. 268-275 8 p.

    Research output: Contribution to journalArticle

  21. Assessment of a Full Dilatation Cesarean Delivery Simulator

    Vousden, N., Hamakarim, Z., Briley, A., Girling, J., Seed, P. T., Tydeman, G. & Shennan, A. H., 2015, In : Obstetrics and Gynecology.

    Research output: Contribution to journalArticle

  22. Parsing the role of NADPH oxidase enzymes and reactive oxygen species in heart failure

    Shah, A. M., 2015, In : Circulation (Baltimore). 131, 7, p. 602-604 3 p.

    Research output: Contribution to journalArticle

  23. Science forum: RIPOSTE: a framework for improving the design and analysis of laboratory-based research.

    Masca, N. G. D., Hensor, E. M. A., Cornelius, V. R., Buffa, F. M., Marriott, H. M., Eales, J. M., Messenger, M. P., Anderson, A. E., Boot, C., Bunce, C., Goldin, R. D., Harris, J., Hinchliffe, R. F., Junaid, H., Kingston, S., Martin-Ruiz, C., Nelson, C. P., Peacock, J., Seed, P. T., Shinkins, B. & 4 others, Staples, K. J., Toombs, J., Wright, A. K. A. & Teare, M. D., 2015, eLife. p. e05519 (eLife; vol. 4).

    Research output: Chapter in Book/Report/Conference proceedingChapter

  24. 2014
  25. Menthol inhibits detrusor contractility independently of TRPM8 Activation

    Ramos-Filho, A. C. S., Shah, A., Augusto, T. M., Barbosa, G. O., Leiria, L. O., De Carvalho, H. F., Antunes, E. & Grant, A. D., 6 Nov 2014, In : PL o S One . 9, 11, e111616.

    Research output: Contribution to journalArticle

  26. AN INTERVENTION TRIAL FOR PEOPLE WITH EPILEPSY ATTENDING A&E

    Ridsdale, L. L., McCrone, P. R., Morgan, M. A., Seed, P., Goldstein, L. H. & Noble, A. J., 1 Oct 2014, In : Journal of Neurology, Neurosurgery and Psychiatry. 85, e4, p. A20 1 p., 075.

    Research output: Contribution to journalMeeting abstract

  27. Endocervical and high vaginal quantitative fetal fibronectin in predicting preterm birth

    Kuhrt, K., Unwin, C., Hezelgrave, N., Seed, P. & Shennan, A., 1 Oct 2014, In : JOURNAL OF MATERNAL FETAL AND NEONATAL MEDICINE. 27, 15, p. 1576-1579 4 p.

    Research output: Contribution to journalArticle

  28. NADPH oxidase 2 mediates angiotensin II-dependent cellular arrhythmias via PKA and CaMKII

    Wagner, S., Dantz, C., Flebbe, H., Azizian, A., Sag, C. M., Engels, S., Möllencamp, J., Dybkova, N., Islam, T., Shah, A. M. & Maier, L. S., 1 Oct 2014, In : Journal of Molecular and Cellular Cardiology. 75, p. 206-215 10 p.

    Research output: Contribution to journalArticle

  29. Prediction of gestational diabetes in obese pregnant women from the UK Pregnancies Better Eating and Activity (UPBEAT) pilot trial

    Maitland, R. A., Seed, P. T., Briley, A. L., Homsy, M., Thomas, S., Pasupathy, D., Robson, S. C., Nelson, S. M., Sattar, N., Poston, L. & UPBEAT Trial Consortium, Aug 2014, In : Diabetic Medicine. 31, 8, p. 963-970 8 p.

    Research output: Contribution to journalArticle

  30. Preface for redox signalling in the cardiovascular system

    Eaton, P. & Shah, A. M., Aug 2014, In : Journal of Molecular and Cellular Cardiology. 73, p. 1-1 1 p.

    Research output: Contribution to journalEditorial

  31. Redox regulation of cardiac hypertrophy

    Sag, C. M., Santos, C. X. C. & Shah, A. M., Aug 2014, In : Journal of Molecular and Cellular Cardiology. 73, p. 103-111 9 p.

    Research output: Contribution to journalLiterature review

  32. The imbalanced redox status in senescent endothelial cells is due to dysregulated Thioredoxin-1 and NADPH oxidase 4

    Goy, C., Czypiorski, P., Altschmied, J., Jakob, S., Rabanter, L. L., Brewer, A. C., Ale-Agha, N., Dyballa-Rukes, N., Shah, A. M. & Haendeler, J., Aug 2014, In : Experimental Gerontology. 56, p. 45-52 8 p.

    Research output: Contribution to journalArticle

  33. Association between response to ovarian stimulation and miscarriage following IVF: an analysis of 124 351 IVF pregnancies

    Sunkara, S., Khalaf, Y., Maheshwari, A., Seed, P. & Coomarasamy, A., Jun 2014, In : Human Reproduction. 29, 6, p. 1218-1224 7 p.

    Research output: Contribution to journalArticle

  34. Erratum: The oxygen-rich postnatal environment induces cardiomyocyte cell-cycle arrest through DNA damage response (Cell (2014) 157 (741-743))

    Puente, B. N., Kimura, W., Muralidhar, S. A., Moon, J., Amatruda, J. F., Phelps, K. L., Grinsfelder, D., Rothermel, B. A., Chen, R., Garcia, J. A., Santos, C. X., Thet, S., Mori, E., Kinter, M. T., Rindler, P. M., Zacchigna, S., Mukherjee, S., Chen, D. J., Mahmoud, A. I., Giacca, M. & 5 others, Rabinovitch, P. S., Asaithamby, A., Shah, A. M., Szweda, L. I. & Sadek, H. A., 22 May 2014, In : Cell. 157, 5, 1 p.

    Research output: Contribution to journalComment/debate

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