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Research Outputs

  1. 2016
  2. A Multicenter Cohort Study of Histologic Findings and Long-Term Outcomes of Kidney Disease in Women Who Have Been Pregnant

    Webster, P., Webster, L. M., Cook, H. T., Horsfield, C., Seed, P. T., Vaz, R., Santos, C., Lydon, I., Homsy, M., Lightstone, L. & Bramham, K., 9 Dec 2016, In : Clinical journal of the American Society of Nephrology : CJASN.

    Research output: Contribution to journalArticle

  3. Early Antenatal Prediction of Gestational Diabetes in Obese Women: Development of Prediction Tools for Targeted Intervention

    White, S. L., Lawlor, D. A., Briley, A. L., Godfrey, K. M., Nelson, S. M., Oteng-Ntim, E., Robson, S. C., Sattar, N., Seed, P. T., Costa Vieira, M., Welsh, P., Whitworth, M., Poston, L., Pasupathy, D. & UPBEAT Consortium, 8 Dec 2016, In : PLoS ONE. 11, 12, 17 p., e0167846.

    Research output: Contribution to journalArticle

  4. From the exposome to mechanistic understanding of chemical-induced adverse effects

    Escher, B. I., Hackermüller, J., Polte, T., Scholz, S., Aigner, A., Altenburger, R., Böhme, A., Bopp, S. K., Brack, W., Busch, W., Chadeau-Hyam, M., Covaci, A., Eisenträger, A., Galligan, J. J., Garcia-Reyero, N., Hartung, T., Hein, M., Herberth, G., Jahnke, A., Kleinjans, J. & 16 others, Klüver, N., Krauss, M., Lamoree, M., Lehmann, I., Luckenbach, T., Miller, G. W., Müller, A., Phillips, D. H., Reemtsma, T., Rolle-Kampczyk, U., Schüürmann, G., Schwikowski, B., Tan, Y-M., Trump, S., Walter-Rohde, S. & Wambaugh, J. F., 8 Dec 2016, In : Environment International.

    Research output: Contribution to journalArticle

  5. Macroprolactinomas and Nonfunctioning Pituitary Adenomas and Pregnancy Outcomes

    Lambert, K., Rees, K., Seed, P. T., Dhanjal, M. K., Knight, M., McCance, D. R. & Williamson, C., 2 Dec 2016, In : Obstetrics and Gynecology. 10 p.

    Research output: Contribution to journalArticle

  6. Dietary patterns in obese pregnant women; Influence of a behavioral intervention of diet and physical activity in the UPBEAT randomized controlled trial

    Flynn, A. C., Seed, P. T., Patel, N., Barr, S., Bell, R., Briley, A. L., Godfrey, K. M., Nelson, S. M., Oteng-Ntim, E., Robinson, S. M., Sanders, T. A., Sattar, N., Wardle, J., Poston, L. & Goff, L. M., 29 Nov 2016, In : The international journal of behavioral nutrition and physical activity. 13, 1, 124.

    Research output: Contribution to journalArticle

  7. Mutational signatures associated with tobacco smoking in human cancer

    Alexandrov, L. B., Ju, Y. S., Haase, K., Van Loo, P., Martincorena, I., Nik-Zainal, S., Totoki, Y., Fujimoto, A., Nakagawa, H., Shibata, T., Campbell, P. J., Vineis, P., Phillips, D. H. & Stratton, M. R., 4 Nov 2016, In : Science. 354, 6312, p. 618-622 5 p.

    Research output: Contribution to journalArticle

  8. Placental Growth Factor (PlGF) in Women with Suspected Pre-Eclampsia Prior to 35 Weeks' Gestation: A Budget Impact Analysis

    Duckworth, S., Chappell, L. C., Seed, P. T., Mackillop, L., Shennan, A. H. & Hunter, R., 14 Oct 2016, In : PLoS ONE. 11, 10, p. e0164276 12 p.

    Research output: Contribution to journalArticle

  9. Vaginal Progesterone Prophylaxis for Preterm Birth (the OPPTIMUM Study): A Multicentre, Randomized, Double-Blind Trial

    Norman, J. E., Marlow, N., Messow, C. M., Shennan, A., Bennett, P. R., Thornton, S., Robson, S. C., McConnachie, A., Petrou, S., Sebire, N. J., Lavender, T., Whyte, S. & Norrie, J., 1 Sep 2016, In : Obstetrical and Gynecological Survey. 71, 9, p. 517-518 2 p.

    Research output: Contribution to journalComment/debate

  10. NADH:Cytochrome b5 reductase and cytochrome b5 can act as sole electron donors to human cytochrome P450 1A1-mediated oxidation and DNA adduct formation by benzo[a]pyrene

    Stiborova, M., Indra, R., Moserova, M., Frei, E., Schmeiser, H. H., Kopka, K., Phillips, D. H. & Arlt, V. M., 15 Aug 2016, In : Chemical Research in Toxicology. 29, 8, p. 1325-1334

    Research output: Contribution to journalArticle

  11. Risk of preterm birth following surgical treatment for cervical disease: executive summary of a recent symposium

    Sasieni, P., Castanon, A., Landy, R., Kyrgiou, M., Kitchener, H., Quigley, M., Poon, L. C. Y., Shennan, A., Hollingworth, A., Soutter, W. P., Freeman-Wang, T., Peebles, D., Prendiville, W. & Patnick, J., 1 Aug 2016, In : BJOG: An International Journal of Obstetrics and Gynaecology. 123, 9, p. 1426-1429 4 p.

    Research output: Contribution to journalComment/debate

  12. Risk of preterm birth following treatment for cervical disease: Stakeholder meeting summary

    Sasieni, P., Castanon, A., Landy, R., Kyrgiou, M., Kitchener, H., Quigley, M., Poon, C. Y. L., Shennan, A., Paraskevaidis, E., Hollingworth, A., Soutter, P., Freeman Wang, T., Peebles, D., Prendeville, W. & Patnick, J., Aug 2016, In : Ultrasound in Obstetrics and Gynecology. 123, 9, p. 1426-1429

    Research output: Contribution to journalArticle

  13. Diagnostic Biomarkers in Women With Suspected Preeclampsia in a Prospective Multicenter Study

    Duckworth, S., Griffin, M., Seed, P. T., North, R., Myers, J., Mackillop, L., Simpson, N., Waugh, J., Anumba, D., Kenny, L. C., Redman, C. W. G., Shennan, A. H. & Chappell, L. C., 7 Jul 2016, In : Obstetrics and Gynecology.

    Research output: Contribution to journalArticle

  14. 9 Pregnancy and chronic hypertension: Nifedipine vs labetalol as antihypertensive treatment (the panda study): Anti-hypertensive medications

    Webster, L., Myers, J., Nelson-piercy, C., Watt-Coote, I., Wiesender, C., Seed, P. T. & Chappell, L. C., Jul 2016, In : Pregnancy Hypertension. 6, 3, p. 141 1 p.

    Research output: Contribution to journalMeeting abstract

  15. Hysteroscopy in recurrent in-vitro fertilisation failure (TROPHY): a multicentre, randomised controlled trial

    El-Toukhy, T., Campo, R., Khalaf, Y., Tabanelli, C., Gianaroli, L., Gordts, S. S., Gordts, S., Mestdagh, G., Mardesic, T., Voboril, J., Marchino, G. L., Benedetto, C., Al-Shawaf, T., Sabatini, L., Seed, P. T., Gergolet, M., Grimbizis, G., Harb, H. & Coomarasamy, A., 25 Jun 2016, In : Lancet. 387, 10038, p. 2614-2621 8 p.

    Research output: Contribution to journalArticle

  16. Placental growth factor as a marker of fetal growth restriction caused by placental dysfunction

    Benton, S. J., Mccowan, L. M., Heazell, A. E. P., Grynspan, D., Hutcheon, J. A., Senger, C., Burke, O., Chan, Y., Harding, J. E., Yockell-Lelièvre, J., Hu, Y., Chappell, L. C., Griffin, M. J., Shennan, A. H., Magee, L. A., Gruslin, A. & Von Dadelszen, P., Jun 2016, In : Placenta. 42, p. 1-8

    Research output: Contribution to journalArticle

  17. Transcriptional profiling of the mouse hippocampus supports an NMDAR-mediated neurotoxic mode of action for benzo[a]pyrene

    Chepelev, N. L., Long, A. S., Bowers, W. J., Gagné, R., Williams, A., Kuo, B., Phillips, D. H., Arlt, V. M., White, P. A. & Yauk, C. L., Jun 2016, In : Environmental and Molecular Mutagenesis. 57, 5, p. 350–363

    Research output: Contribution to journalArticle

  18. Vaginal progesterone prophylaxis for preterm birth (the OPPTIMUM study): a multicentre, randomised, double-blind trial

    Norman, J. E., Marlow, N., Messow, C-M., Shennan, A., Bennett, P. R., Thornton, S., Robson, S. C., McConnachie, A., Petrou, S., Sebire, N. J., Lavender, T., Whyte, S., Norrie, J. & OPPTIMUM study group, 21 May 2016, In : Lancet. 387, 10033, p. 2106–2116

    Research output: Contribution to journalArticle

  19. PROMISE: first-trimester progesterone therapy in women with a history of unexplained recurrent miscarriages - a randomised, double-blind, placebo-controlled, international multicentre trial and economic evaluation

    Coomarasamy, A., Williams, H., Truchanowicz, E., Seed, P. T., Small, R., Quenby, S., Gupta, P., Dawood, F., Koot, Y. E., Atik, R. B., Bloemenkamp, K. W., Brady, R., Briley, A., Cavallaro, R., Cheong, Y. C., Chu, J., Eapen, A., Essex, H., Ewies, A., Hoek, A. & 18 others, Kaaijk, E. M., Koks, C. A., Li, T-C., MacLean, M., Mol, B. W., Moore, J., Parrott, S., Ross, J. A., Sharpe, L., Stewart, J., Trépel, D., Vaithilingam, N., Farquharson, R. G., Kilby, M. D., Khalaf, Y., Goddijn, M., Regan, L. & Rai, R., May 2016, In : Health technology assessment (Winchester, England). 20, 41, p. 1-92 92 p.

    Research output: Contribution to journalArticle

  20. Midwife-led continuity models versus other models of care for childbearing women

    Sandall, J., Soltani, H., Gates, S., Shennan, A. H. & Devane, D., 28 Apr 2016, In : Cochrane Database of Systematic Reviews. 2015, 9, p. 1-122 CD004667.

    Research output: Contribution to journalLiterature review

  21. A clinical opinion on how to manage the risk of preterm birth in twins based on literature review

    Collins, A. & Shennan, A., 2 Apr 2016, In : The Journal of Maternal-Fetal & Neonatal Medicine. 29, 7, p. 1125-1130 6 p.

    Research output: Contribution to journalReview article

  22. Prognostic and mechanistic potential of progesterone sulfates in intrahepatic cholestasis of pregnancy and pruritus gravidarum

    Abu-Hayyeh, S., Ovadia, C., Lieu, T., Jensen, D. D., Chambers, J., Dixon, P. H., Lövgren-Sandblom, A., Bolier, R., Tolenaars, D., Kremer, A. E., Syngelaki, A., Noori, M., Williams, D., Marin, J. J. G., Monte, M. J., Nicolaides, K. H., Beuers, U., Oude-Elferink, R., Seed, P. T., Chappell, L. & 3 others, Marschall, H-U., Bunnett, N. W. & Williamson, C., Apr 2016, In : Hepatology. 63, 4

    Research output: Contribution to journalArticle

  23. The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice

    Krais, A. M., Speksnijder, E. N., Melis, J. P. M., Indra, R., Moserova, M., Godschalk, R. W., van Schooten, F-J., Seidel, A., Kopka, K., Schmeiser, H. H., Stiborova, M., Phillips, D. H., Luijten, M. & Arlt, V. M., Apr 2016, In : Archives of Toxicology. 90, 4, p. 839-851 13 p.

    Research output: Contribution to journalArticle

  24. Vital Sign Prediction of Adverse Maternal Outcomes in Women with Hypovolemic Shock: The Role of Shock Index

    El Ayadi, A. M., Nathan, H. L., Seed, P. T., Butrick, E. A., Hezelgrave, N. L., Shennan, A. H. & Miller, S., 22 Feb 2016, In : PLoS ONE. 11, 2, p. e0148729

    Research output: Contribution to journalArticle

  25. Metabolic activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and DNA adduct formation depends on p53: studies in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice

    Krais, A. M., Speksnijder, E. N., Melis, J. P. M., Singh, R., Caldwell, A., Gamboa da Costa, G., Luijten, M., Phillips, D. H. & Arlt, V. M., 15 Feb 2016, In : International Journal of Cancer. 138, 4, p. 976–982

    Research output: Contribution to journalArticle

  26. Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism

    Wohak, L., Krais, A. M., Kucab, J. E., Stertmann, J., Ovrebø, S., Seidel, A., Phillips, D. H. & Arlt, V. M., 1 Feb 2016, In : Archives of Toxicology. 90, 2, p. 291-304 14 p.

    Research output: Contribution to journalArticle

  27. Quantitative Fetal Fibronectin at 18 Weeks of Gestation to Predict Preterm Birth in Asymptomatic High-Risk Women

    Hezelgrave Elliott, N., Abbott, D. S., Radford, S. K., Seed, P. T., Girling, J. C., Filmer, J., Tribe, R. M. & Shennan, A. H., 1 Feb 2016, In : Obstetrics and Gynecology. 127, 2, p. 255-263 9 p.

    Research output: Contribution to journalArticle

  28. Quantitative fetal fibronectin to predict spontaneous preterm birth: A review

    Hezelgrave, N. L. & Shennan, A. H., 1 Jan 2016, In : BMC Women's Health. 12, 1, p. 121-128 8 p.

    Research output: Contribution to journalArticle

  29. Transcriptional profiling of dibenzo[def, p]chrysene-induced spleen atrophy provides mechanistic insights into its immunotoxicity in mutamouse

    Chepelev, N. L., Long, A. S., Williams, A., Kuo, B., Gagné, R., Kennedy, D. A., Phillips, D. H., Arlt, V. M., White, P. A. & Yauk, C. L., 1 Jan 2016, In : Toxicological Sciences. 149, 1, p. 251-268 18 p.

    Research output: Contribution to journalArticle

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