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Research Outputs

  1. 2017
  2. Mitochondrial Translocase of the Outer Membrane Alterations May Underlie Dysfunctional Oxidative Phosphorylation in Alzheimer's Disease

    Chai, Y. L., Xing, H., Chong, J. R., Francis, P. T., Ballard, C. G., Chen, C. P. & Lai, M. K. P., 19 Dec 2017, In : JOURNAL OF ALZHEIMERS DISEASE. 61, 2, p. 793-801 9 p.

    Research output: Contribution to journalArticle

  3. Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease

    Horgusluoglu-Moloch, E., Nho, K., Risacher, S. L., Kim, S., Foroud, T., Shaw, L. M., Trojanowski, J. Q., Aisen, P. S., Petersen, R. C., Jack, C. R., Lovestone, S., Simmons, A., Weiner, M. W. & Saykin, A. J., 1 Dec 2017, In : Neurobiology of Aging. 60, p. 92-103 12 p.

    Research output: Contribution to journalArticle

  4. Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study

    C Vieira, M., White, S. L., Patel, N., Seed, P. T., Briley, A. L., Sandall, J., Welsh, P., Sattar, N., Nelson, S. M., Lawlor, D. A., Poston, L., Pasupathy, D. & UPBEAT Consortium, 3 Nov 2017, In : BMC Medicine. 15, 1, p. 194

    Research output: Contribution to journalArticle

  5. AN EVALUATION OF PREDICTORS AND COGNITIVE DECLINE ASSOCIATED WITH PERSISTENT AND TRANSIENT PSYCHOTIC SYMPTOMS IN ALZHEIMER’S DISEASE: 2017 Abstract Supplement

    Creese, B., Ballard, C., Aarsland, D., Bergh, S., Rongve, A. & Selbaek, G., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P367

    Research output: Contribution to journalPoster abstract

  6. DISCOVERY, REPLICATION AND EXTENSION STUDY OF PLASMA PROTEOMIC BIOMARKERS RELATING TO BRAIN AMYLOID BURDEN (CSF Aβ OR AMYLOID-PET) IN THE EMIF-AD BIOMARKER DISCOVERY COHORT: 2017 Abstract Supplement

    Westwood, S., Baird, A. L., Hye, A., Bos, I., Vos, S. J. B., Vandenberghe, R., Scheltens, P., Engelborghs, S., Frisoni, G. B., Molinuevo, J. L., Wallin, A., Lleó, A., Popp, J., Martinez-Lage, P., Snowden, S. G., Legido-Quigley, C., Bertram, L., Barkhof, F., Zetterberg, H., Streffer, J. & 2 others, Visser, P. J. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P361-P362

    Research output: Contribution to journalArticle

  7. PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY: 2017 Abstract Supplement

    Koychev, I. G., Gunn, R. N., Firouzian, A., Lawson, J., Zamboni, G., Ridha, B. H., Sahakian, B., Rowe, J. B., Thomas, A., Rochester, L., Ffytche, D., Howard, R. J., Zetterberg, H., MacKay, C. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P243

    Research output: Contribution to journalPoster abstract

  8. PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY: 2017 Abstract Supplement

    Koychev, I. G., Gunn, R. N., Firouzian, A., Lawson, J., Zamboni, G., Ridha, B. H., Sahakian, B., Rowe, J. B., Thomas, A., Rochester, L., Ffytche, D., Howard, R. J., Zetterberg, H., MacKay, C. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P456-P457

    Research output: Contribution to journalPoster abstract

  9. PREVALENCE AND CO-MORBIDITY OF APATHY AND DEPRESSION IN ALZHEIMER’S DISEASE: 2017 Abstract Supplement

    Johar, I., Aarsland, D., Ballard, C., Bergh, S., Fossey, J., Kirkevold, Ø., Medboen, I. T., Orrell, M., Rongve, A., Selbaek, G., Skarpenes, S. B. & Creese, B., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P371-P372

    Research output: Contribution to journalPoster abstract

  10. Amyloid beta synaptotoxicity is Wnt–planar cell polarity dependent and blocked by fasudil

    Sellers, K. J., Elliott, C., Jackson, J., Ghosh, A., Ribe, E., Rojo-Sanchís, A., Jarosz-Griffiths, H. H., Watson, I. A., Xia, W., Semenov, M., Morin, P., Hooper, N. M., Porter, R., Preston, J., Al-Shawi, R., Baillie, G., Lovestone, S., Cuadrado, A., Harte, M., Simons, P. & 2 others, Srivastava, D. P. & Killick, R., 19 Oct 2017, In : Alzheimer's & Dementia.

    Research output: Contribution to journalArticle

  11. Hormone-secreting adrenal tumours cause severe hypertension and high rates of poor pregnancy outcome: a UKOSS study with case control comparisons

    Quartermaine, G., Lambert, K., Rees, K., Seed, P. T., Dhanjal, M. K., Knight, M., McCance, D. R. & Williamson, C., 5 Sep 2017, In : BJOG.

    Research output: Contribution to journalArticle

  12. Neuropsychiatric signs and symptoms of Alzheimer's disease: New treatment paradigms

    Lanctôt, K. L., Amatniek, J., Ancoli-Israel, S., Arnold, S. E., Ballard, C., Cohen-Mansfield, J., Ismail, Z., Lyketsos, C., Miller, D. S., Musiek, E., Osorio, R. S., Rosenberg, P. B., Satlin, A., Steffens, D., Tariot, P., Bain, L. J., Carrillo, M. C., Hendrix, J. A., Jurgens, H. & Boot, B., Sep 2017, In : Alzheimers & Dementia. 3, 3, p. 440-449 10 p.

    Research output: Contribution to journalArticle

  13. New Therapeutic Strategies for Lewy Body Dementias

    Velayudhan, L., Ffytche, D., Ballard, C. & Aarsland, D., Sep 2017, In : CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS. 17, 9, p. 68

    Research output: Contribution to journalReview article

  14. Accuracy of Clinical Diagnosis of Dementia with Lewy Bodies versus Neuropathology

    Skogseth, R. E., Hortobágyi, T., Soennesyn, H., Chwiszczuk, L., Ffytche, D., Rongve, A., Ballard, C. & Aarsland, D., 14 Aug 2017, In : JOURNAL OF ALZHEIMERS DISEASE. 59, 4, p. 1139-1152 14 p.

    Research output: Contribution to journalArticle

  15. OP 2 Placental growth factor informed management of suspected pre-eclampsia and/or fetal growth restriction: The MAPPLE cohort study

    Sharp, A., Chappell, L., Dekker, G., Pelletier, S., Garnier, Y., Zeren, O., Hillerer, K. M., Fischer, T., Seed, P., Turner, M., Shennan, A. & Alfirevic, Z., 12 Aug 2017, In : Pregnancy Hypertension. 9, p. 9-10 2 p.

    Research output: Contribution to journalMeeting abstract

  16. Metabolic profiling of gestational diabetes in obese women during pregnancy

    White, S. L., Pasupathy, D., Sattar, N., Nelson, S. M., Lawlor, D. A., Briley, A. L., Seed, P. T., Welsh, P., Poston, L. & UPBEAT Consortium, 1 Aug 2017, In : Diabetologia. 60, 10, p. 1603-1912 10 p.

    Research output: Contribution to journalArticle

  17. Dementia prevention, intervention, and care

    Livingston, G., Sommerlad, A., Orgeta, V., Costafreda, S. G., Huntley, J., Ames, D., Ballard, C., Banerjee, S., Burns, A., Cohen-Mansfield, J., Cooper, C., Fox, N., Gitlin, L. N., Howard, R., Kales, H. C., Larson, E. B., Ritchie, K., Rockwood, K., Sampson, E. L., Samus, Q. & 4 others, Schneider, L. S., Selbæk, G., Teri, L. & Mukadam, N., 20 Jul 2017, In : Lancet.

    Research output: Contribution to journalArticle

  18. EXPLORING THE RELATIONSHIP BETWEEN ANAEMIA AND ALZHEIMER’S DISEASE: 2017 Abstract Supplement

    Winchester, L., Nevado-Holgado, A. J. & Lovestone, S., 20 Jul 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P221

    Research output: Contribution to journalMeeting abstract

  19. NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology

    Rojo, A. I., Pajares, M., Rada, P., Nuñez, A., Nevado-Holgado, A. J., Killik, R., Van Leuven, F., Ribe, E., Lovestone, S., Yamamoto, M. & Cuadrado, A., 5 Jul 2017, In : Redox Biology.

    Research output: Contribution to journalArticle

  20. Emerging amyloid and tau targeting treatments for Alzheimer’s disease

    Khan, A., Corbett, A. & Ballard, C., 3 Jul 2017, In : Expert Review of Neurotherapeutics. 17, 7, p. 697-711 15 p.

    Research output: Contribution to journalReview article

  21. DISCOVERY AND VALIDATION OF MULTIMODAL BIOMARKER SIGNATURES RELATING TO ALZHEIMER'S DISEASE PATHOLOGY AND PROGRESSION: 2017 Abstract Supplement

    Westwood, S., Hye, A., Lleó, A., Nevado-Holgado, A. J., Baird, A. L., Wallin, A., Leslie, A., Jimenez, B., Liu, B. Y., Legido-Quigley, C., Dima, D., Ruvolo, D., Holmes, E., D'Hondt, E., Westman, E., Barkhof, F., Frisoni, G. B., Zetterberg, H., Bos, I., Pearce, J. & 27 others, Streffer, J., Molinuevo, J. L., Popp, J., Bertram, L., Whiley, L., Maslen, L., Gomez-Romero, M., David, M., Lewis, M., Kurbatova, N., Ashton, N. J., Voyle, N., Kowalczyk, O., Martinez-Lage, P., Proitsi, P., Scheltens, P., Visser, P. J., Dobson, R. JB., Vandenberghe, R., Engelborghs, S., Vos, S. J. B., Snowden, S. G., Athersuch, T., Ashby, T., Kimhofer, T., Verachtert, W. & Lovestone, S., Jul 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P174-P175

    Research output: Contribution to journalMeeting abstract

  22. IMPACT OF WHELD INTERVENTION ON NEUROPSYCHIATRIC SYMPTOMS, ANTIPSYCHOTIC USE AND QUALITY OF LIFE IN PEOPLE WITH DEMENTIA LIVING IN NURSING HOMES: A CLUSTER-RANDOMIZED TRIAL: 2017 Abstract Supplement

    Ballard, C., Fossey, J., Corbett, A., Orrell, M., Romeo, R., Moniz-Cook, E., Woods, B. & Whitaker, R., Jul 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P171

    Research output: Contribution to journalMeeting abstract

  23. Core outcome measures for interventions to prevent or slow the progress of dementia for people living with mild to moderate dementia: Systematic review and consensus recommendations

    Webster, L., Groskreutz, D., Grinbergs-Saull, A., Howard, R., O'Brien, J. T., Mountain, G., Banerjee, S., Woods, B., Perneczky, R., Lafortune, L., Roberts, C., McCleery, J., Pickett, J., Bunn, F., Challis, D., Charlesworth, G., Featherstone, K., Fox, C., Goodman, C., Jones, R. & 17 others, Lamb, S., Moniz-Cook, E., Schneider, J., Shepperd, S., Surr, C., Thompson-Coon, J., Ballard, C., Brayne, C., Burns, A., Clare, L., Garrard, P., Kehoe, P., Passmore, P., Holmes, C., Maidment, I., Robinson, L. & Livingston, G., 29 Jun 2017, In : PLoS ONE. 12, 6, p. e0179521

    Research output: Contribution to journalArticle

  24. HYdroxychloroquine to Improve Pregnancy Outcome in Women with AnTIphospholipid Antibodies (HYPATIA) Protocol: A Multinational Randomized Controlled Trial of Hydroxychloroquine versus Placebo in Addition to Standard Treatment in Pregnant Women with Antiphospholipid Syndrome or Antibodies

    Schreiber, K., Breen, K., Cohen, H., Jacobsen, S., Middeldorp, S., Pavord, S., Regan, L., Roccatello, D., Robinson, S. E., Sciascia, S., Seed, P. T., Watkins, L. & Hunt, B. J., 13 Jun 2017, In : Seminars in Thrombosis and Hemostasis.

    Research output: Contribution to journalArticle

  25. Maternal BMI and diabetes in pregnancy: Investigating variations between ethnic groups using routine maternity data from London, UK

    Nishikawa, E., Oakley, L., Seed, P., Doyle, P. & Oteng-Ntim, E., 1 Jun 2017, In : PL o S One . 12, 6, e0179332.

    Research output: Contribution to journalArticle

  26. Emerging treatments for Alzheimer's disease for non-amyloid and non-tau targets

    Khan, A., Corbett, A. & Ballard, C., 18 May 2017, In : Expert Review of Neurotherapeutics. p. 1-13 13 p.

    Research output: Contribution to journalArticle

  27. Feasibility of a staff training and support programme to improve pain assessment and management in people with dementia living in care homes

    Petyaeva, A., Kajander, M., Lawrence, V., Ballard, C., Clifton, L., Thomas, A., Leroi, I., Briggs, M., Jose Closs, S., Dening, T., Nunez, K-M., Testad, I., Romeo, R. & Corbett, A., 5 May 2017, In : International Journal of Geriatric Psychiatry.

    Research output: Contribution to journalArticle

  28. Mitochondrial genes are altered in blood early in Alzheimer's disease

    Lunnon, K., Keohane, A., Pidsley, R., Newhouse, S., Riddoch-Contreras, J., Thubron, E. B., Devall, M., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Schalkwyk, L., Dobson, R., Malik, A. N., Powell, J., Lovestone, S. & Hodges, A., 1 May 2017, In : Neurobiology of Aging. 53, p. 36-47 12 p.

    Research output: Contribution to journalArticle

  29. Development of a core outcome set for disease modification trials in mild to moderate dementia: a systematic review, patient and public consultation and consensus recommendations

    Webster, L., Groskreutz, D., Grinbergs-Saull, A., Howard, R., O'Brien, J. T., Mountain, G., Banerjee, S., Woods, B., Perneczky, R., Lafortune, L., Roberts, C., McCleery, J., Pickett, J., Bunn, F., Challis, D., Charlesworth, G., Featherstone, K., Fox, C., Goodman, C., Jones, R. & 19 others, Lamb, S., Moniz-Cook, E., Schneider, J., Shepperd, S., Surr, C., Thompson-Coon, J., Ballard, C., Brayne, C., Burke, O., Burns, A., Clare, L., Garrard, P., Kehoe, P., Passmore, P., Holmes, C., Maidment, I., Murtagh, F., Robinson, L. & Livingston, G., May 2017, In : Health technology assessment (Winchester, England). 21, 26, p. 1-192 192 p.

    Research output: Contribution to journalArticle

  30. Historical landmarks in dementia with Lewy bodies

    Mueller, C., Ballard, C., Corbett, A. & Aarsland, D., May 2017, In : Lancet Neurology. 16, 5, p. 348

    Research output: Contribution to journalArticle

  31. The prognosis of dementia with Lewy bodies

    Mueller, C., Ballard, C., Corbett, A. & Aarsland, D., May 2017, In : Lancet Neurology. 16, 5, p. 390-398 9 p.

    Research output: Contribution to journalArticle

  32. Cognitive decline in Parkinson disease

    Aarsland, D., Creese, B., Politis, M., Ray Chaudhuri, K., Ffytche, D. H., Weintraub, D. & Ballard, C., Apr 2017, In : Nature Reviews Neurology. 13, p. 217–231

    Research output: Contribution to journalArticle

  33. Reduction of RPT6/S8 (a Proteasome Component) and Proteasome Activity in the Cortex is Associated with Cognitive Impairment in Lewy Body Dementia

    Alghamdi, A., Vallortigara, J., Howlett, D. R., Broadstock, M., Hortobágyi, T., Ballard, C., Thomas, A. J., O'Brien, J. T., Aarsland, D., Attems, J., Francis, P. T. & Whitfield, D. R., 21 Mar 2017, In : JOURNAL OF ALZHEIMERS DISEASE. 57, 2, p. 373-386 14 p., DOI 10.3233/JAD-160946.

    Research output: Contribution to journalArticle

  34. Effect of reproductive ageing on pregnant mouse uterus and cervix

    Patel, R., Moffatt, J. D., Mourmoura, E., Demaison, L., Seed, P. T., Poston, L. & Tribe, R. M., 15 Mar 2017, In : The Journal of physiology. 595, 6, p. 2065–2084

    Research output: Contribution to journalArticle

  35. Reply: Rapid changes in practice make analysis of historical databases irrelevant for contemporary counselling

    Sunkara, S. K., Lamarca, A., Polyzos, N. P., Seed, P. T. & Khalaf, Y., 25 Feb 2017, In : Human reproduction (Oxford, England). 32, 4, p. 964-965 2 p.

    Research output: Contribution to journalArticle

  36. Infant adiposity following a randomised controlled trial of a behavioural intervention in obese pregnancy

    Patel, N., Godfrey, K. M., Pasupathy, D., Levin, J., Flynn, A. C., Hayes, L., Briley, A. L., Bell, R., Lawlor, D. A., Oteng-Ntim, E., Nelson, S. M., Robson, S. C., Sattar, N., Singh, C., Wardle, J., White, S., Seed, P. T. & Poston, L., 20 Feb 2017, In : International Journal of Obesity.

    Research output: Contribution to journalArticle

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