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  1. 2017
  2. Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation

    Nabeebaccus, A. A., Zoccarato, A., Hafstad, A. D., Santos, C. X., Aasum, E., Brewer, A. C., Zhang, M., Beretta, M., Yin, X., West, J. A., Schröder, K., Griffin, J. L., Eykyn, T. R., Abel, E. D., Mayr, M. & Shah, A. M., 21 Dec 2017, In : JCI Insight. 2, 24

    Research output: Contribution to journalArticle

  3. Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease

    Horgusluoglu-Moloch, E., Nho, K., Risacher, S. L., Kim, S., Foroud, T., Shaw, L. M., Trojanowski, J. Q., Aisen, P. S., Petersen, R. C., Jack, C. R., Lovestone, S., Simmons, A., Weiner, M. W. & Saykin, A. J., 1 Dec 2017, In : Neurobiology of Aging. 60, p. 92-103 12 p.

    Research output: Contribution to journalArticle

  4. Plasma Proteomics for Epidemiology: Increasing Throughput with Standard-Flow Rates

    Yin, X., Baig, F., Haudebourg, E., Blankley, R. T., Gandhi, T., Müller, S., Reiter, L., Hinterwirth, H., Pechlaner, R., Tsimikas, S., Santer, P., Willeit, J., Kiechl, S., Witztum, J. L., Sullivan, A. & Mayr, M., Dec 2017, In : Circulation-Cardiovascular Genetics. 10, 6

    Research output: Contribution to journalArticle

  5. Cardiac myocyte miR-29 promotes pathological remodeling of the heart by activating Wnt signaling

    Sassi, Y., Avramopoulos, P., Ramanujam, D., Grüter, L., Werfel, S., Giosele, S., Brunner, A-D., Esfandyari, D., Papadopoulou, A. S., De Strooper, B., Hübner, N., Kumarswamy, R., Thum, T., Yin, X., Mayr, M., Laggerbauer, B. & Engelhardt, S., 20 Nov 2017, In : Nature Communications. 8, 1, p. 1614 1 p.

    Research output: Contribution to journalArticle

  6. Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study

    C Vieira, M., White, S. L., Patel, N., Seed, P. T., Briley, A. L., Sandall, J., Welsh, P., Sattar, N., Nelson, S. M., Lawlor, D. A., Poston, L., Pasupathy, D. & UPBEAT Consortium, 3 Nov 2017, In : BMC Medicine. 15, 1, p. 194

    Research output: Contribution to journalArticle

  7. Genetic Dissection of the Impact of miR-33a and miR-33b during the Progression of Atherosclerosis

    Price, N. L., Rotllan, N., Canfrán-Duque, A., Zhang, X., Pati, P., Arias, N., Moen, J., Mayr, M., Ford, D. A., Baldán, Á., Suárez, Y. & Fernández-Hernando, C., 31 Oct 2017, In : Cell Reports. 21, 5, p. 1317-1330 14 p.

    Research output: Contribution to journalArticle

  8. DISCOVERY, REPLICATION AND EXTENSION STUDY OF PLASMA PROTEOMIC BIOMARKERS RELATING TO BRAIN AMYLOID BURDEN (CSF Aβ OR AMYLOID-PET) IN THE EMIF-AD BIOMARKER DISCOVERY COHORT: 2017 Abstract Supplement

    Westwood, S., Baird, A. L., Hye, A., Bos, I., Vos, S. J. B., Vandenberghe, R., Scheltens, P., Engelborghs, S., Frisoni, G. B., Molinuevo, J. L., Wallin, A., Lleó, A., Popp, J., Martinez-Lage, P., Snowden, S. G., Legido-Quigley, C., Bertram, L., Barkhof, F., Zetterberg, H., Streffer, J. & 2 others, Visser, P. J. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P361-P362

    Research output: Contribution to journalArticle

  9. PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY: 2017 Abstract Supplement

    Koychev, I. G., Gunn, R. N., Firouzian, A., Lawson, J., Zamboni, G., Ridha, B. H., Sahakian, B., Rowe, J. B., Thomas, A., Rochester, L., Ffytche, D., Howard, R. J., Zetterberg, H., MacKay, C. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P243

    Research output: Contribution to journalPoster abstract

  10. PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY: 2017 Abstract Supplement

    Koychev, I. G., Gunn, R. N., Firouzian, A., Lawson, J., Zamboni, G., Ridha, B. H., Sahakian, B., Rowe, J. B., Thomas, A., Rochester, L., Ffytche, D., Howard, R. J., Zetterberg, H., MacKay, C. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P456-P457

    Research output: Contribution to journalPoster abstract

  11. Amyloid beta synaptotoxicity is Wnt–planar cell polarity dependent and blocked by fasudil

    Sellers, K. J., Elliott, C., Jackson, J., Ghosh, A., Ribe, E., Rojo-Sanchís, A., Jarosz-Griffiths, H. H., Watson, I. A., Xia, W., Semenov, M., Morin, P., Hooper, N. M., Porter, R., Preston, J., Al-Shawi, R., Baillie, G., Lovestone, S., Cuadrado, A., Harte, M., Simons, P. & 2 others, Srivastava, D. P. & Killick, R., 19 Oct 2017, In : Alzheimer's & Dementia.

    Research output: Contribution to journalArticle

  12. Hormone-secreting adrenal tumours cause severe hypertension and high rates of poor pregnancy outcome: a UKOSS study with case control comparisons

    Quartermaine, G., Lambert, K., Rees, K., Seed, P. T., Dhanjal, M. K., Knight, M., McCance, D. R. & Williamson, C., 5 Sep 2017, In : BJOG.

    Research output: Contribution to journalArticle

  13. What are the prospects of apolipoprotein profiling for cardiovascular disease?

    Baig, F. & Mayr, M., 2 Sep 2017, In : EXPERT REVIEW OF MOLECULAR DIAGNOSTICS. 17, 9, p. 805-807 3 p.

    Research output: Contribution to journalEditorial

  14. CRISPR/Cas9 editing reveals novel mechanisms of clustered microRNA regulation and function

    Lataniotis, L., Albrecht, A., Kok, F. O., Monfries, C. A. L., Benedetti, L., Lawson, N. D., Hughes, S., Steinhofel, K., Mayr, M. & Zampetaki, A., 17 Aug 2017, In : Scientific Reports. 7, 1, p. 8585

    Research output: Contribution to journalArticle

  15. OP 2 Placental growth factor informed management of suspected pre-eclampsia and/or fetal growth restriction: The MAPPLE cohort study

    Sharp, A., Chappell, L., Dekker, G., Pelletier, S., Garnier, Y., Zeren, O., Hillerer, K. M., Fischer, T., Seed, P., Turner, M., Shennan, A. & Alfirevic, Z., 12 Aug 2017, In : Pregnancy Hypertension. 9, p. 9-10 2 p.

    Research output: Contribution to journalMeeting abstract

  16. Metabolic profiling of gestational diabetes in obese women during pregnancy

    White, S. L., Pasupathy, D., Sattar, N., Nelson, S. M., Lawlor, D. A., Briley, A. L., Seed, P. T., Welsh, P., Poston, L. & UPBEAT Consortium, 1 Aug 2017, In : Diabetologia. 60, 10, p. 1603-1912 10 p.

    Research output: Contribution to journalArticle

  17. Downregulation of MicroRNA-126 Augments DNA Damage Response in Cigarette Smokers and COPD Patients

    Paschalaki, K. E., Zampetaki, A., Baker, J. R., Birrell, M. A., Starke, R. D., Belvisi, M. G., Donnelly, L. E., Mayr, M., Randi, A. M. & Barnes, P. J., 28 Jul 2017, In : American Journal of Respiratory and Critical Care Medicine.

    Research output: Contribution to journalArticle

  18. EXPLORING THE RELATIONSHIP BETWEEN ANAEMIA AND ALZHEIMER’S DISEASE: 2017 Abstract Supplement

    Winchester, L., Nevado-Holgado, A. J. & Lovestone, S., 20 Jul 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P221

    Research output: Contribution to journalMeeting abstract

  19. NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology

    Rojo, A. I., Pajares, M., Rada, P., Nuñez, A., Nevado-Holgado, A. J., Killik, R., Van Leuven, F., Ribe, E., Lovestone, S., Yamamoto, M. & Cuadrado, A., 5 Jul 2017, In : Redox Biology.

    Research output: Contribution to journalArticle

  20. Long Noncoding RNAs and Angiogenesis: Regulatory Information for Chromatin Remodeling

    Zampetaki, A. & Mayr, M., 3 Jul 2017, In : Circulation (Baltimore). 136, 1, p. 80-82

    Research output: Contribution to journalArticle

  21. DISCOVERY AND VALIDATION OF MULTIMODAL BIOMARKER SIGNATURES RELATING TO ALZHEIMER'S DISEASE PATHOLOGY AND PROGRESSION: 2017 Abstract Supplement

    Westwood, S., Hye, A., Lleó, A., Nevado-Holgado, A. J., Baird, A. L., Wallin, A., Leslie, A., Jimenez, B., Liu, B. Y., Legido-Quigley, C., Dima, D., Ruvolo, D., Holmes, E., D'Hondt, E., Westman, E., Barkhof, F., Frisoni, G. B., Zetterberg, H., Bos, I., Pearce, J. & 27 others, Streffer, J., Molinuevo, J. L., Popp, J., Bertram, L., Whiley, L., Maslen, L., Gomez-Romero, M., David, M., Lewis, M., Kurbatova, N., Ashton, N. J., Voyle, N., Kowalczyk, O., Martinez-Lage, P., Proitsi, P., Scheltens, P., Visser, P. J., Dobson, R. JB., Vandenberghe, R., Engelborghs, S., Vos, S. J. B., Snowden, S. G., Athersuch, T., Ashby, T., Kimhofer, T., Verachtert, W. & Lovestone, S., Jul 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P174-P175

    Research output: Contribution to journalMeeting abstract

  22. HYdroxychloroquine to Improve Pregnancy Outcome in Women with AnTIphospholipid Antibodies (HYPATIA) Protocol: A Multinational Randomized Controlled Trial of Hydroxychloroquine versus Placebo in Addition to Standard Treatment in Pregnant Women with Antiphospholipid Syndrome or Antibodies

    Schreiber, K., Breen, K., Cohen, H., Jacobsen, S., Middeldorp, S., Pavord, S., Regan, L., Roccatello, D., Robinson, S. E., Sciascia, S., Seed, P. T., Watkins, L. & Hunt, B. J., 13 Jun 2017, In : Seminars in Thrombosis and Hemostasis.

    Research output: Contribution to journalArticle

  23. Proteomics of the epicardial fat secretome and its role in post-operative atrial fibrillation

    Viviano, A., Yin, X., Zampetaki, A., Fava, M., Gallagher, M., Mayr, M. & Jahangiri, M., 5 Jun 2017, In : EUROPACE. eux113.

    Research output: Contribution to journalArticle

  24. Maternal BMI and diabetes in pregnancy: Investigating variations between ethnic groups using routine maternity data from London, UK

    Nishikawa, E., Oakley, L., Seed, P., Doyle, P. & Oteng-Ntim, E., 1 Jun 2017, In : PL o S One . 12, 6, e0179332.

    Research output: Contribution to journalArticle

  25. CRISPR/CAS9 GENE EDITING REVEALS NOVEL TERTIARY CONSTRAINTS IN CLUSTERED MIRNA PROCESSING

    Lataniotis, L., Albrecht, A., Kok, F., Monfries, C., Benedetti, L., Lawson, N. D., Hughes, S. M., Steinhofel, K., Mayr, M. & Zampetaki, A., Jun 2017, In : Heart. 103, p. A133-A133

    Research output: Contribution to journalArticle

  26. Epigenomic and transcriptomic approaches in the post-genomic era: path to novel targets for diagnosis and therapy of the ischaemic heart? Position Paper of the European Society of Cardiology Working Group on Cellular Biology of the Heart

    Perrino, C., Barabási, A-L., Condorelli, G., Davidson, S. M., De Windt, L., Dimmeler, S., Engel, F. B., Hausenloy, D. J., Hill, J. A., Van Laake, L. W., Lecour, S., Leor, J., Madonna, R., Mayr, M., Prunier, F., Sluijter, J. P. G., Schulz, R., Thum, T., Ytrehus, K. & Ferdinandy, P., Jun 2017, In : Cardiovascular Research. 113, 7, p. 725-736 12 p.

    Research output: Contribution to journalArticle

  27. Mitochondria and ageing: Role in heart, skeletal muscle and adipose tissue

    Boengler, K., Kosiol, M., Mayr, M., Schulz, R. & Rohrbach, S., Jun 2017, In : Journal of cachexia sarcopenia and muscle. 8, 3, p. 349–369

    Research output: Contribution to journalArticle

  28. Mitochondrial genes are altered in blood early in Alzheimer's disease

    Lunnon, K., Keohane, A., Pidsley, R., Newhouse, S., Riddoch-Contreras, J., Thubron, E. B., Devall, M., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Schalkwyk, L., Dobson, R., Malik, A. N., Powell, J., Lovestone, S. & Hodges, A., 1 May 2017, In : Neurobiology of Aging. 53, p. 36-47 12 p.

    Research output: Contribution to journalArticle

  29. Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques

    Langley, S. R., Willeit, K., Didangelos, A., Matic, L. P., Skroblin, P., Barallobre-barreiro, J., Lengquist, M., Rungger, G., Kapustin, A., Kedenko, L., Molenaar, C., Lu, R., Barwari, T., Suna, G., Yin, X., Iglseder, B., Paulweber, B., Willeit, P., Shalhoub, J., Pasterkamp, G. & 7 others, Davies, A. H., Monaco, C., Hedin, U., Shanahan, C. M., Willeit, J., Kiechl, S. & Mayr, M., 3 Apr 2017, In : Journal of Clinical Investigation. 127, 4, p. 1546-1560

    Research output: Contribution to journalArticle

  30. Effect of reproductive ageing on pregnant mouse uterus and cervix

    Patel, R., Moffatt, J. D., Mourmoura, E., Demaison, L., Seed, P. T., Poston, L. & Tribe, R. M., 15 Mar 2017, In : The Journal of physiology. 595, 6, p. 2065–2084

    Research output: Contribution to journalArticle

  31. Reply: Rapid changes in practice make analysis of historical databases irrelevant for contemporary counselling

    Sunkara, S. K., Lamarca, A., Polyzos, N. P., Seed, P. T. & Khalaf, Y., 25 Feb 2017, In : Human reproduction (Oxford, England). 32, 4, p. 964-965 2 p.

    Research output: Contribution to journalArticle

  32. Very-Low-Density Lipoprotein–Associated Apolipoproteins Predict Cardiovascular Events and Are Lowered by Inhibition of APOC-III

    Pechlaner, R., Tsimikas, S., Yin, X., Willeit, P., Baig, F., Santer, P., Oberhollenzer, F., Egger, G., Witztum, J. L., Alexander, V. J., Willeit, J., Kiechl, S. & Mayr, M., 21 Feb 2017, In : Journal of the American College of Cardiology. 69, 7, p. 789-800 12 p.

    Research output: Contribution to journalArticle

  33. Infant adiposity following a randomised controlled trial of a behavioural intervention in obese pregnancy

    Patel, N., Godfrey, K. M., Pasupathy, D., Levin, J., Flynn, A. C., Hayes, L., Briley, A. L., Bell, R., Lawlor, D. A., Oteng-Ntim, E., Nelson, S. M., Robson, S. C., Sattar, N., Singh, C., Wardle, J., White, S., Seed, P. T. & Poston, L., 20 Feb 2017, In : International Journal of Obesity.

    Research output: Contribution to journalArticle

  34. A Multi-Cohort Study of ApoE ϵ 4 and Amyloid-β Effects on the Hippocampus in Alzheimer's Disease

    Khan, W., Giampietro, V., Banaschewski, T., Barker, G. J., Bokde, A. L. W., Büchel, C., Conrod, P., Flor, H., Frouin, V., Garavan, H., Gowland, P., Heinz, A., Ittermann, B., Lemaître, H., Nees, F., Paus, T., Pausova, Z., Rietschel, M., Smolka, M. N., Ströhle, A. & 19 others, Gallinat, J., Vellas, B., Soininen, H., Kloszewska, I., Tsolaki, M., Mecocci, P., Spenger, C., Villemagne, V. L., Masters, C. L., Muehlboeck, J. S., Bäckman, L., Fratiglioni, L., Kalpouzos, G., Wahlund, L. O., Schumann, G., Lovestone, S., Williams, S. C. R., Westman, E. & Simmons, A., 3 Feb 2017, In : JOURNAL OF ALZHEIMERS DISEASE. 56, 3, p. 1159-1174 16 p.

    Research output: Contribution to journalArticle

  35. Circulating MicroRNA-122 is associated with the risk of new-onset metabolic syndrome and type 2 diabetes

    Willeit, P., Skroblin, P., Moschen, A. R., Yin, X., Kaudewitz, D., Zampetaki, A., Barwari, T., Whitehead, M., Ramírez, C. M., Goedeke, L., Rotllan, N., Bonora, E., Hughes, A. D., Santer, P., Fernández-Hernando, C., Tilg, H., Willeit, J., Kiechl, S. & Mayr, M., 1 Feb 2017, In : Diabetes. 66, 2, p. 347-357 11 p.

    Research output: Contribution to journalArticle

  36. High-density lipoproteins in high resolution: Will proteomics solve the paradox for cardiovascular risk?

    Baig, F., Joshi, A. & Mayr, M., 1 Feb 2017, In : Proteomics. 17, 3-4, 1600426.

    Research output: Contribution to journalComment/debate

  37. MicroRNA Biomarkers and Platelet Reactivity: The Clot Thickens

    Sunderland, N., Skroblin, P., Barwari, T., Huntley, R. P., Lu, R., Joshi, A., Lovering, R. C. & Mayr, M., 20 Jan 2017, In : Circulation Research. 120, 2, p. 418-435 18 p.

    Research output: Contribution to journalReview article

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