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Research Outputs

  1. 2017
  2. Imaging the human placental microcirculation with micro-focus computed tomography: Optimisation of tissue preparation and image acquisition

    Pratt, R., Hutchinson, J. C., Melbourne, A., Zuluaga, M. A., Virasami, A., Vercauteren, T., Ourselin, S., Sebire, N. J., Arthurs, O. J. & David, A. L., 1 Dec 2017, In : Placenta. 60, p. 36-39 4 p.

    Research output: Contribution to journalArticle

  3. Looking beyond the imaging plane: 3D needle tracking with a linear array ultrasound probe

    Xia, W., West, S. J., Finlay, M. C., Mari, J. M., Ourselin, S., David, A. L. & Desjardins, A. E., 1 Dec 2017, In : Scientific Reports. 7, 1, p. 2380-2296 3674.

    Research output: Contribution to journalArticle

  4. Through-needle all-optical ultrasound imaging in vivo: A preclinical swine study

    Finlay, M. C., Mosse, C. A., Colchester, R. J., Noimark, S., Zhang, E. Z., Ourselin, S., Beard, P. C., Schillin, R. J., Parkin, I. P., Papakonstantinou, I. & Desjardins, A. E., 1 Dec 2017, In : Light: Science and Applications. 6, 12, e17103.

    Research output: Contribution to journalArticle

  5. Whole-body MRI quantitative biomarkers are associated significantly with treatment response in patients with newly diagnosed symptomatic multiple myeloma following bortezomib induction

    Latifoltojar, A., Hall-Craggs, M., Bainbridge, A., Rabin, N., Popat, R., Rismani, A., D’Sa, S., Dikaios, N., Sokolska, M., Antonelli, M., Ourselin, S., Yong, K., Taylor, S. A., Halligan, S. & Punwani, S., Dec 2017, In : European Radiology. 27, 12, p. 5325-5336 12 p.

    Research output: Contribution to journalArticle

  6. Investigating the maturation of microstructure and radial orientation in the preterm human cortex with diffusion MRI

    Eaton-Rosen, Z., Scherrer, B., Melbourne, A., Ourselin, S., Neil, J. J. & Warfield, S. K., 15 Nov 2017, In : NeuroImage. 162, p. 65-72 8 p.

    Research output: Contribution to journalArticle

  7. Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study

    C Vieira, M., White, S. L., Patel, N., Seed, P. T., Briley, A. L., Sandall, J., Welsh, P., Sattar, N., Nelson, S. M., Lawlor, D. A., Poston, L., Pasupathy, D. & UPBEAT Consortium, 3 Nov 2017, In : BMC Medicine. 15, 1, p. 194

    Research output: Contribution to journalArticle

  8. The TMEM106B risk allele is associated with lower cortical volumes in a clinically diagnosed frontotemporal dementia cohort

    Harding, S. R., Bocchetta, M., Gordon, E., Cash, D. M., Cash, D. M., Cardoso, M. J., Druyeh, R., Ourselin, S., Warren, J. D., Mead, S. & Rohrer, J. D., 1 Nov 2017, In : Journal of Neurology, Neurosurgery and Psychiatry. 88, 11, p. 997-999 3 p.

    Research output: Contribution to journalArticle

  9. Probabilistic disease progression modeling to characterize diagnostic uncertainty: Application to staging and prediction in Alzheimer's disease

    Lorenzi, M., Filippone, M., Frisoni, G. B., Alexander, D. C., Ourselin, S. & Alzheimer's Disease Neuroimaging Initiative, 24 Oct 2017, In : NeuroImage.

    Research output: Contribution to journalArticle

  10. PATHOLOGICAL CORRELATES OF WHITE MATTER HYPERINTENSITIES ON CADAVERIC MRI IN PROGRANULIN-ASSOCIATED FRONTOTEMPORAL DEMENTIA

    Woollacott, I. OC., Bocchetta, M., Sudre, C. H., Ridha, B. H., Strand, C., Courtney, R., Ourselin, S., Cardoso, J. M., Warren, J. D., Rossor, M. N., Fox, N. C., Revesz, T., Lashley, T., Holton, J. & Rohrer, J. D., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, p. P805

    Research output: Contribution to journalArticle

  11. VASCULAR AND EARLY LIFE INFLUENCES ON CEREBROVASCULAR DISEASE IN INSIGHT 46: A SUB-STUDY OF THE MRC NATIONAL SURVEY OF HEALTH AND DEVELOPMENT (NSHD) BRITISH BIRTH COHORT

    Lane, C. A., Sudre, C. H., Barnes, J., Nicholas, J. M., Parker, T., Cash, D. M., Murray-Smith, H., Wong, A., Malone, I. B., Klimova, J., Kuh, D., Ourselin, S., Cardoso, M. J., Richards, M., Fox, N. C. & Schott, J. M., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, p. P851-P853

    Research output: Contribution to journalArticle

  12. WHITE MATTER HYPERINTENSITIES AND VASCULAR RISK FACTORS IN COGNITIVELY HEALTHY ELDERLY MONOZYGOTIC TWIN PAIRS

    Kate, M. T., Sudre, C. H., Braber, A. D., Konijnenberg, E., Cardoso, M. J., Scheltens, P., Ourselin, S., Boomsma, D. I., Barkhof, F. & Visser, P. J., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, p. P53-P54

    Research output: Contribution to journalArticle

  13. WHITE MATTER HYPERINTENSITIES IN GENETIC FRONTOTEMPORAL DEMENTIA: A GENFI STUDY

    Sudre, C. H., Bocchetta, M., Cash, D. M., Thomas, D. L., Woollacott, I. OC., Dick, K. M., van Swieten, J. C., Borroni, B., Galimberti, D., Masellis, M., Tartaglia, M. C., Rowe, J. B., Graff, C., Tagliavini, F., Frisoni, G. B., Laforce, R., Finger, E., de Mendonca, A., Sorbi, S., Ourselin, S. & 2 others, Cardoso, M. J. & Rohrer, J. D., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, p. P9-P10

    Research output: Contribution to journalArticle

  14. The 19th International Conference on Medical Image Computing and Computer-Assisted Intervention (MICCAI 2016)

    Ourselin, S., Sabuncu, M. R., Wells, W., Joskowicz, L., Unal, G. & Maier, A., Oct 2017, In : Medical Image Analysis. 41, 1 p.

    Research output: Contribution to journalArticle

  15. EP22.19: Investigating the effect of umbilical cord insertion site on placental perfusion

    Vercauteren, T., Hutchinson, C., Arthurs, O., Pratt, R., Sebire, N. J., Melbourne, A., David, A. L. & Ourselin, S., 18 Sep 2017, p. 363-364. 2 p.

    Research output: Contribution to conference typesAbstract

  16. OP05.08: Novel placental evaluation using multimodal MRI

    David, A. L., Deprest, J., Atkinson, D., Owen, D., Kendall, G., Bainbridge, A., Sokolska, M., Melbourne, A., Vercauteren, T., Ourselin, S. & Pratt, R., 18 Sep 2017, p. 62-62. 1 p.

    Research output: Contribution to conference typesAbstract

  17. Hormone-secreting adrenal tumours cause severe hypertension and high rates of poor pregnancy outcome: a UKOSS study with case control comparisons

    Quartermaine, G., Lambert, K., Rees, K., Seed, P. T., Dhanjal, M. K., Knight, M., McCance, D. R. & Williamson, C., 5 Sep 2017, In : BJOG.

    Research output: Contribution to journalArticle

  18. Automated T2 relaxometry of the hippocampus for temporal lobe epilepsy

    Winston, G. P., Vos, S. B., Burdett, J. L., Cardoso, M. J., Ourselin, S. & Duncan, J. S., Sep 2017, In : Epilepsia. 58, 9, p. 1645-1652 8 p.

    Research output: Contribution to journalArticle

  19. The Bionic Clicker Mark I & II

    Magee, E. G., Ourselin, S., Nikitichev, D., Vercauteren, T. & Vanhoestenberghe, A., 14 Aug 2017, In : Journal of visualized experiments : JoVE. 126

    Research output: Contribution to journalArticle

  20. Metabolic profiling of gestational diabetes in obese women during pregnancy

    White, S. L., Pasupathy, D., Sattar, N., Nelson, S. M., Lawlor, D. A., Briley, A. L., Seed, P. T., Welsh, P., Poston, L. & UPBEAT Consortium, 1 Aug 2017, In : Diabetologia. 60, 10, p. 1603-1912 10 p.

    Research output: Contribution to journalArticle

  21. Anatomy-driven multiple trajectory planning (ADMTP) of intracranial electrodes for epilepsy surgery

    Sparks, R., Vakharia, V., Rodionov, R., Vos, S. B., Diehl, B., Wehner, T., Miserocchi, A., McEvoy, A. W., Duncan, J. S. & Ourselin, S., Aug 2017, In : International Journal of Computer Assisted Radiology and Surgery. 12, 8, p. 1245-1255 11 p.

    Research output: Contribution to journalArticle

  22. Effect of high-dose simvastatin on cognitive, neuropsychiatric, and health-related quality-of-life measures in secondary progressive multiple sclerosis: secondary analyses from the MS-STAT randomised, placebo-controlled trial

    Chan, D., Binks, S., Nicholas, J. M., Frost, C., Cardoso, M. J., Ourselin, S., Wilkie, D., Nicholas, R. & Chataway, J., Aug 2017, In : The Lancet Neurology. 16, 8, p. 591-600 10 p.

    Research output: Contribution to journalArticle

  23. A novel scheme for the validation of an automated classification method for epileptic spikes by comparison with multiple observers

    Sharma, N. K., Pedreira, C., Centeno, M., Chaudhary, U. J., Wehner, T., França, L. G. S., Yadee, T., Murta, T., Leite, M., Vos, S. B., Ourselin, S., Diehl, B. & Lemieux, L., 1 Jul 2017, In : Clinical Neurophysiology. 128, 7, p. 1246-1254 9 p.

    Research output: Contribution to journalArticle

  24. A Continuum Robot and Control Interface for Surgical Assist in Fetoscopic Interventions

    Dwyer, G., Chadebecq, F., Tella Amo, M., Bergeles, C., Maneas, E., Pawar, V., Vander Poorten, E., Deprest, J., Ourselin, S., De Coppi, P., Vercauteren, T. & Stoyanov, D., Jul 2017, In : IEEE Robotics and Automation Letters. 2, 3, p. 1656-1663 8 p.

    Research output: Contribution to journalArticle

  25. HYdroxychloroquine to Improve Pregnancy Outcome in Women with AnTIphospholipid Antibodies (HYPATIA) Protocol: A Multinational Randomized Controlled Trial of Hydroxychloroquine versus Placebo in Addition to Standard Treatment in Pregnant Women with Antiphospholipid Syndrome or Antibodies

    Schreiber, K., Breen, K., Cohen, H., Jacobsen, S., Middeldorp, S., Pavord, S., Regan, L., Roccatello, D., Robinson, S. E., Sciascia, S., Seed, P. T., Watkins, L. & Hunt, B. J., 13 Jun 2017, In : Seminars in Thrombosis and Hemostasis.

    Research output: Contribution to journalArticle

  26. Evaluation of a direct motion estimation/correction method in respiratory-gated PET/MRI with motion-adjusted attenuation

    Bousse, A., Manber, R., Holman, B. F., Atkinson, D., Arridge, S., Ourselin, S., Hutton, B. F. & Thielemans, K., 1 Jun 2017, In : Medical Physics. 44, 6, p. 2379-2390 12 p.

    Research output: Contribution to journalArticle

  27. Maternal BMI and diabetes in pregnancy: Investigating variations between ethnic groups using routine maternity data from London, UK

    Nishikawa, E., Oakley, L., Seed, P., Doyle, P. & Oteng-Ntim, E., 1 Jun 2017, In : PL o S One . 12, 6, e0179332.

    Research output: Contribution to journalArticle

  28. Cognitive reserve and TMEM106B genotype modulate brain damage in presymptomatic frontotemporal dementia: A GENFI study

    Premi, E., Grassi, M., Van Swieten, J., Galimberti, D., Graff, C., Masellis, M., Tartaglia, C., Tagliavini, F., Rowe, J. B., Laforce, R., Finger, E., Frisoni, G. B., De Mendonça, A., Sorbi, S., Gazzina, S., Cosseddu, M., Archetti, S., Gasparotti, R., Manes, M., Alberici, A. & 7 others, Cardoso, M. J., Bocchetta, M., Cash, D. M., Ourselin, S., Padovani, A., Rohrer, J. D. & Borroni, B., Jun 2017, In : Brain. 140, 6, p. 1784-1791 8 p.

    Research output: Contribution to journalArticle

  29. Real-time imaging of single neuronal cell apoptosis in patients with glaucoma

    Cordeiro, M. F., Normando, E. M., Cardoso, M. J., Miodragovic, S., Jeylani, S., Davis, B. M., Guo, L., Ourselin, S., A'Hern, R. & Bloom, P. A., Jun 2017, In : Brain. 140, 6, p. 1757-1767 11 p.

    Research output: Contribution to journalArticle

  30. Unsupervised identification of cone photoreceptors in non-confocal adaptive optics scanning light ophthalmoscope images

    Bergeles, C., Dubis, A. M., Davidson, B., Kasilian, M., Kalitzeos, A., Carroll, J., Dubra, A., Michaelides, M. & Ourselin, S., Jun 2017, In : Biomedical Optics Express. 8, 6, #288055.

    Research output: Contribution to journalArticle

  31. Spinal cord grey matter segmentation challenge

    Prados, F., Ashburner, J., Blaiotta, C., Brosch, T., Carballido-Gamio, J., Cardoso, M. J., Conrad, B. N., Datta, E., Dávid, G., Leener, B. D., Dupont, S. M., Freund, P., Wheeler-Kingshott, C. A. M. G., Grussu, F., Henry, R., Landman, B. A., Ljungberg, E., Lyttle, B., Ourselin, S., Papinutto, N. & 8 others, Saporito, S., Schlaeger, R., Smith, S. A., Summers, P., Tam, R., Yiannakas, M. C., Zhu, A. & Cohen-Adad, J., 15 May 2017, In : NeuroImage. 152, p. 312-329 18 p.

    Research output: Contribution to journalArticle

  32. Iterative framework for the joint segmentation and CT synthesis of MR images: Application to MRI-only radiotherapy treatment planning

    Burgos, N., Guerreiro, F., McClelland, J., Presles, B., Modat, M., Nill, S., Dearnaley, D., DeSouza, N., Oelfke, U., Knopf, A. C., Ourselin, S. & Jorge Cardoso, M., 5 May 2017, In : Physics in Medicine and Biology. 62, 11, p. 4237-4253 17 p.

    Research output: Contribution to journalArticle

  33. Longitudinal segmentation of age-related white matter hyperintensities

    Sudre, C. H., Cardoso, M. J., Ourselin, S. & Alzheimer's Disease Neuroimaging Initiative, 1 May 2017, In : Medical Image Analysis. 38, p. 50-64 15 p.

    Research output: Contribution to journalArticle

  34. APOE ε4 status is associated with white matter hyperintensities volume accumulation rate independent of AD diagnosis

    Sudre, C. H., Cardoso, M. J., Frost, C., Barnes, J., Barkhof, F., Fox, N. & Ourselin, S., May 2017, In : Neurobiology of Aging. 53, p. 67-75 9 p.

    Research output: Contribution to journalArticle

  35. Study protocol: Insight 46: a neuroscience sub-study of the MRC National Survey of Health and Development

    Lane, C. A., Parker, T. D., Cash, D. M., Macpherson, K., Donnachie, E., Murray-Smith, H., Barnes, A., Barker, S., Beasley, D. G., Bras, J., Brown, D., Burgos, N., Byford, M., Cardoso, M. J., Carvalho, A., Collins, J., De Vita, E., Dickson, J. C., Epie, N., Espak, M. & 23 others, Henley, S. M. D., Hoskote, C., Hutel, M., Klimova, J., Malone, I. B., Markiewicz, P., Melbourne, A., Modat, M., Schrag, A., Shah, S., Sharma, N., Sudre, C. H., Thomas, D. L., Wong, A., Zhang, H., Hardy, J., Zetterberg, H., Ourselin, S., Crutch, S. J., Kuh, D., Richards, M., Fox, N. C. & Schott, J. M., 18 Apr 2017, In : BMC Neurology. 17, 75.

    Research output: Contribution to journalArticle

  36. Comparison of In vivo and Ex vivo MRI for the detection of structural abnormalities in a mouse model of tauopathy

    Holmes, H. E., Powell, N. M., Ma, D., Ismail, O., Harrison, I. F., Wells, J. A., Colgan, N., O’Callaghan, J. M., Johnson, R. A., Murray, T. K., Ahmed, Z., Heggenes, M., Fisher, A., Cardoso, M. J., Modat, M., O’Neill, M. J., Collins, E. C., Fisher, E. M. C., Ourselin, S. & Lythgoe, M. F., 31 Mar 2017, In : Frontiers in Neuroinformatics. 11, 20.

    Research output: Contribution to journalArticle

  37. Effect of reproductive ageing on pregnant mouse uterus and cervix

    Patel, R., Moffatt, J. D., Mourmoura, E., Demaison, L., Seed, P. T., Poston, L. & Tribe, R. M., 15 Mar 2017, In : The Journal of physiology. 595, 6, p. 2065–2084

    Research output: Contribution to journalArticle

  38. Early microgliosis precedes neuronal loss and behavioural impairment in mice with a frontotemporal dementia-causing CHMP2B mutation

    FReJA, Clayton, E. L., Mancuso, R., Tolstrup Nielsen, T., Mizielinska, S., Holmes, H., Powell, N., Norona, F., Overgaard Larsen, J., Milioto, C., Wilson, K. M., Lythgoe, M. F., Ourselin, S., Nielsen, J. E., Johannsen, P., Holm, I., Collinge, J., Oliver, P. L., Gomez-Nicola, D., Isaacs, A. M. & 9 others, Gade, A., Englund, E., Fisher, E., Brown, J., Stockholm, J., Roos, P., Gydesen, S., Lindquist, S. & Thusgaard, T., 1 Mar 2017, In : Human Molecular Genetics. 26, 5, p. 873-887 15 p., ddx003.

    Research output: Contribution to journalArticle

  39. Evaluation of a multi-atlas CT synthesis approach for MRI-only radiotherapy treatment planning

    Guerreiro, F., Burgos, N., Dunlop, A., Wong, K., Petkar, I., Nutting, C., Harrington, K., Bhide, S., Newbold, K., Dearnaley, D., deSouza, N. M., Morgan, V. A., McClelland, J., Nill, S., Cardoso, M. J., Ourselin, S., Oelfke, U. & Knopf, A. C., 1 Mar 2017, In : Physica Medica. 35, p. 7-17 11 p.

    Research output: Contribution to journalArticle

  40. Longitudinal multiple sclerosis lesion segmentation: Resource and challenge

    Carass, A., Roy, S., Jog, A., Cuzzocreo, J. L., Magrath, E., Gherman, A., Button, J., Nguyen, J., Prados, F., Sudre, C. H., Jorge Cardoso, M., Cawley, N., Ciccarelli, O., Wheeler-Kingshott, C. A. M., Ourselin, S., Catanese, L., Deshpande, H., Maurel, P., Commowick, O., Barillot, C. & 26 others, Tomas-Fernandez, X., Warfield, S. K., Vaidya, S., Chunduru, A., Muthuganapathy, R., Krishnamurthi, G., Jesson, A., Arbel, T., Maier, O., Handels, H., Iheme, L. O., Unay, D., Jain, S., Sima, D. M., Smeets, D., Ghafoorian, M., Platel, B., Birenbaum, A., Greenspan, H., Bazin, P. L., Calabresi, P. A., Crainiceanu, C. M., Ellingsen, L. M., Reich, D. S., Prince, J. L. & Pham, D. L., 1 Mar 2017, In : NeuroImage. 148, p. 77-102 26 p.

    Research output: Contribution to journalArticle

  41. White matter hyperintensities are associated with disproportionate progressive hippocampal atrophy

    Fiford, C. M., Manning, E. N., Bartlett, J. W., Cash, D. M., Malone, I. B., Ridgway, G. R., Lehmann, M., Leung, K. K., Sudre, C. H., Ourselin, S., Biessels, G. J., Carmichael, O. T., Fox, N. C., Cardoso, M. J., Barnes, J. & for the Alzheimer's Disease Neuroimaging Initiative, Mar 2017, In : Hippocampus. 27, 3, p. 249-262 14 p.

    Research output: Contribution to journalArticle

  42. Reply: Rapid changes in practice make analysis of historical databases irrelevant for contemporary counselling

    Sunkara, S. K., Lamarca, A., Polyzos, N. P., Seed, P. T. & Khalaf, Y., 25 Feb 2017, In : Human reproduction (Oxford, England). 32, 4, p. 964-965 2 p.

    Research output: Contribution to journalArticle

  43. Medical-grade sterilizable target for fluid-immersed fetoscope optical distortion calibration

    Nikitichev, D. I., Shakir, D. I., Chadebecq, F., Tella, M., Deprest, J., Stoyanov, D., Ourselin, S. & Vercauteren, T., 23 Feb 2017, In : Journal of Visualized Experiments. 2017, 120, e55298.

    Research output: Contribution to journalArticle

  44. Infant adiposity following a randomised controlled trial of a behavioural intervention in obese pregnancy

    Patel, N., Godfrey, K. M., Pasupathy, D., Levin, J., Flynn, A. C., Hayes, L., Briley, A. L., Bell, R., Lawlor, D. A., Oteng-Ntim, E., Nelson, S. M., Robson, S. C., Sattar, N., Singh, C., Wardle, J., White, S., Seed, P. T. & Poston, L., 20 Feb 2017, In : International Journal of Obesity.

    Research output: Contribution to journalArticle

  45. A multi-centre evaluation of eleven clinically feasible brain PET/MRI attenuation correction techniques using a large cohort of patients

    Ladefoged, C. N., Law, I., Anazodo, U., Lawrence, K. S., Izquierdo-Garcia, D., Catana, C., Burgos, N., Cardoso, M. J., Ourselin, S., Hutton, B., Mérida, I., Costes, N., Hammers, A., Benoit, D., Holm, S., Juttukonda, M., An, H., Cabello, J., Lukas, M., Nekolla, S. & 8 others, Ziegler, S., Fenchel, M., Jakoby, B., Casey, M. E., Benzinger, T., Højgaard, L., Hansen, A. E. & Andersen, F. L., 15 Feb 2017, In : NeuroImage. 147, p. 346-359

    Research output: Contribution to journalArticle

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