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Research Outputs

  1. 2017
  2. Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease

    Horgusluoglu-Moloch, E., Nho, K., Risacher, S. L., Kim, S., Foroud, T., Shaw, L. M., Trojanowski, J. Q., Aisen, P. S., Petersen, R. C., Jack, C. R., Lovestone, S., Simmons, A., Weiner, M. W. & Saykin, A. J., 1 Dec 2017, In : Neurobiology of Aging. 60, p. 92-103 12 p.

    Research output: Contribution to journalArticle

  3. Is a SIMPLe smartphone application capable of improving biological rhythms in bipolar disorder?

    Hidalgo-Mazzei, D., Reinares, M., Mateu, A., Jururena, M. F., Young, A. H., Pérez-Sola, V., Vieta, E. & Colom, F., Dec 2017, In : Journal of Affective Disorders. 223, p. 10-16 7 p.

    Research output: Contribution to journalArticle

  4. The evidence for lithium in suicide prevention

    Roberts, E., Cipriani, A., Geddes, J. R., Nierenberg, A. A. & Young, A. H., Dec 2017, In : British Journal of Psychiatry. 211, 6, p. 396 1 p.

    Research output: Contribution to journalLetter

  5. Use of licensed medicines for unlicensed applications in psychiatric practice

    Aitchinson, K. J., Baldwin, D. S., Barnes, T. R. E., Hall, J., Howes, O. D., McAllister-Williams, R. H., Shoka, A., Stokes, P., Young, A., Browning, M. D., Eberhard, J., Harrison, P. & Peter, T., Dec 2017, 2 ed. Royal College of Psychiatrists. 15 p.

    Research output: Book/ReportBook

  6. Anxiety, irritability, and agitation as indicators of bipolar mania with depressive symptoms: a post hoc analysis of two clinical trials

    Suppes, T., Eberhard, J., Lemming, O., Young, A. H. & McIntyre, R. S., 6 Nov 2017, In : International Journal of Bipolar Disorders. 5, 1, p. 36 IJBD-D-17-00017R1.

    Research output: Contribution to journalArticle

  7. Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study

    C Vieira, M., White, S. L., Patel, N., Seed, P. T., Briley, A. L., Sandall, J., Welsh, P., Sattar, N., Nelson, S. M., Lawlor, D. A., Poston, L., Pasupathy, D. & UPBEAT Consortium, 3 Nov 2017, In : BMC Medicine. 15, 1, p. 194

    Research output: Contribution to journalArticle

  8. DISCOVERY, REPLICATION AND EXTENSION STUDY OF PLASMA PROTEOMIC BIOMARKERS RELATING TO BRAIN AMYLOID BURDEN (CSF Aβ OR AMYLOID-PET) IN THE EMIF-AD BIOMARKER DISCOVERY COHORT: 2017 Abstract Supplement

    Westwood, S., Baird, A. L., Hye, A., Bos, I., Vos, S. J. B., Vandenberghe, R., Scheltens, P., Engelborghs, S., Frisoni, G. B., Molinuevo, J. L., Wallin, A., Lleó, A., Popp, J., Martinez-Lage, P., Snowden, S. G., Legido-Quigley, C., Bertram, L., Barkhof, F., Zetterberg, H., Streffer, J. & 2 others, Visser, P. J. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P361-P362

    Research output: Contribution to journalArticle

  9. PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY: 2017 Abstract Supplement

    Koychev, I. G., Gunn, R. N., Firouzian, A., Lawson, J., Zamboni, G., Ridha, B. H., Sahakian, B., Rowe, J. B., Thomas, A., Rochester, L., Ffytche, D., Howard, R. J., Zetterberg, H., MacKay, C. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P243

    Research output: Contribution to journalPoster abstract

  10. PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY: 2017 Abstract Supplement

    Koychev, I. G., Gunn, R. N., Firouzian, A., Lawson, J., Zamboni, G., Ridha, B. H., Sahakian, B., Rowe, J. B., Thomas, A., Rochester, L., Ffytche, D., Howard, R. J., Zetterberg, H., MacKay, C. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P456-P457

    Research output: Contribution to journalPoster abstract

  11. Amyloid beta synaptotoxicity is Wnt–planar cell polarity dependent and blocked by fasudil

    Sellers, K. J., Elliott, C., Jackson, J., Ghosh, A., Ribe, E., Rojo-Sanchís, A., Jarosz-Griffiths, H. H., Watson, I. A., Xia, W., Semenov, M., Morin, P., Hooper, N. M., Porter, R., Preston, J., Al-Shawi, R., Baillie, G., Lovestone, S., Cuadrado, A., Harte, M., Simons, P. & 2 others, Srivastava, D. P. & Killick, R., 19 Oct 2017, In : Alzheimer's & Dementia.

    Research output: Contribution to journalArticle

  12. Clinical and demographic differences between patients with manic, depressive and schizophrenia-spectrum psychoses presenting to Early Intervention Services in London

    Kapila, A., Fisher, H. L., Johnson, S., Major, B., Rahaman, N., Joyce, J., Chamberlain-Kent, N., Lawrence, J., Young, A. H. & Stone, J. M., 15 Oct 2017, In : Early Intervention in Psychiatry.

    Research output: Contribution to journalArticle

  13. Monitoring for antidepressant-associated adverse events in the treatment of patients with major depressive disorder: An international consensus statement

    Dodd, S., Mitchell, P. B., Bauer, M., Yatham, L., Young, A. H., Kennedy, S. H., Williams, L., Suppes, T., Lopez Jaramillo, C., Trivedi, M. H., Fava, M., Rush, A. J., McIntyre, R. S., Thase, M. E., Lam, R. W., Severus, E., Kasper, S. & Berk, M., 6 Oct 2017, In : The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. p. 1-19 19 p.

    Research output: Contribution to journalArticle

  14. Aggressiveness in depression: a neglected symptom possibly associated with bipolarity and mixed features

    BRIDGE-II-Mix Study Group, Oct 2017, In : Acta Psychiatrica Scandinavica . 136, 4, p. 362-372 11 p.

    Research output: Contribution to journalArticle

  15. Methodological recommendations for cognition trials in bipolar disorder by the International Society for Bipolar Disorders Targeting Cognition Task Force

    Miskowiak, K. W., Burdick, K. E., Martinez-Aran, A., Bonnin, C. M., Bowie, C. R., Carvalho, A. F., Gallagher, P., Lafer, B., López-Jaramillo, C., Sumiyoshi, T., McIntyre, R. S., Schaffer, A., Porter, R. J., Torres, I. J., Yatham, L. N., Young, A. H., Kessing, L. V. & Vieta, E., 12 Sep 2017, In : Bipolar Disorders.

    Research output: Contribution to journalArticle

  16. Hair cortisol as predictor of psychotherapy response in affective disorders

    Fischer, S., King, S., Papadopoulos, A., Hotopf, M., Young, A. H. & Cleare, A. J., 11 Sep 2017, In : Psychoneuroendocrinology. 83, Supplement, p. 46

    Research output: Contribution to journalMeeting abstract

  17. Hormone-secreting adrenal tumours cause severe hypertension and high rates of poor pregnancy outcome: a UKOSS study with case control comparisons

    Quartermaine, G., Lambert, K., Rees, K., Seed, P. T., Dhanjal, M. K., Knight, M., McCance, D. R. & Williamson, C., 5 Sep 2017, In : BJOG.

    Research output: Contribution to journalArticle

  18. Antidepressant-induced hypomania/mania in patients with major depression: Evidence from the BRIDGE-II-MIX study

    Barbuti, M., Pacchiarotti, I., Vieta, E., Azorin, J. M., Angst, J., Bowden, C. L., Mosolov, S., Young, A. H. & Perugi, G., 1 Sep 2017, In : Journal of Affective Disorders. 219, p. 187-192 6 p.

    Research output: Contribution to journalArticle

  19. Anti-inflammatory treatments for mood disorders: systematic review and meta-analysis

    Husain, M. I., Strawbridge, R., Stokes, P. RA. & Young, A. H., Sep 2017, In : Journal of Psychopharmacology. 31, 9, p. 1137-1148 12 p.

    Research output: Contribution to journalArticle

  20. Minocycline as an adjunct for treatment-resistant depressive symptoms: A pilot randomised placebo-controlled trial

    Husain, M. I., Chaudhry, I. B., Husain, N., Khoso, A. B., Rahman, R. R., Hamirani, M. M., Hodsoll, J., Qurashi, I., Deakin, J. F. & Young, A. H., 31 Aug 2017, In : Journal of Psychopharmacology. 31, 9, p. 1166-1175 10 p.

    Research output: Contribution to journalArticle

  21. Cost-utility evaluation of vortioxetine in patients with Major Depressive Disorder experiencing inadequate response to alternative antidepressants in the United Kingdom

    Young, A. H., Evitt, L., Brignone, M., Diamand, F., Atsou, K., Campbell, R., Cure, S. & Danchenko, N., 15 Aug 2017, In : Journal of Affective Disorders. 218, p. 291-298

    Research output: Contribution to journalArticle

  22. OP 2 Placental growth factor informed management of suspected pre-eclampsia and/or fetal growth restriction: The MAPPLE cohort study

    Sharp, A., Chappell, L., Dekker, G., Pelletier, S., Garnier, Y., Zeren, O., Hillerer, K. M., Fischer, T., Seed, P., Turner, M., Shennan, A. & Alfirevic, Z., 12 Aug 2017, In : Pregnancy Hypertension. 9, p. 9-10 2 p.

    Research output: Contribution to journalMeeting abstract

  23. Metabolic profiling of gestational diabetes in obese women during pregnancy

    White, S. L., Pasupathy, D., Sattar, N., Nelson, S. M., Lawlor, D. A., Briley, A. L., Seed, P. T., Welsh, P., Poston, L. & UPBEAT Consortium, 1 Aug 2017, In : Diabetologia. 60, 10, p. 1603-1912 10 p.

    Research output: Contribution to journalArticle

  24. EXPLORING THE RELATIONSHIP BETWEEN ANAEMIA AND ALZHEIMER’S DISEASE: 2017 Abstract Supplement

    Winchester, L., Nevado-Holgado, A. J. & Lovestone, S., 20 Jul 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P221

    Research output: Contribution to journalMeeting abstract

  25. Obesity in patients with major depression is related to bipolarity and mixed features: evidence from the BRIDGE-II-Mix study

    Petri, E., Bacci, O., Barbuti, M., Pacchiarotti, I., Azorin, J-M., Angst, J., Bowden, C. L., Mosolov, S., Vieta, E., Young, A. H., Perugi, G. & BRIDGE-II-Mix Study Group, 10 Jul 2017, In : Bipolar Disorders.

    Research output: Contribution to journalArticle

  26. NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology

    Rojo, A. I., Pajares, M., Rada, P., Nuñez, A., Nevado-Holgado, A. J., Killik, R., Van Leuven, F., Ribe, E., Lovestone, S., Yamamoto, M. & Cuadrado, A., 5 Jul 2017, In : Redox Biology.

    Research output: Contribution to journalArticle

  27. DISCOVERY AND VALIDATION OF MULTIMODAL BIOMARKER SIGNATURES RELATING TO ALZHEIMER'S DISEASE PATHOLOGY AND PROGRESSION: 2017 Abstract Supplement

    Westwood, S., Hye, A., Lleó, A., Nevado-Holgado, A. J., Baird, A. L., Wallin, A., Leslie, A., Jimenez, B., Liu, B. Y., Legido-Quigley, C., Dima, D., Ruvolo, D., Holmes, E., D'Hondt, E., Westman, E., Barkhof, F., Frisoni, G. B., Zetterberg, H., Bos, I., Pearce, J. & 27 others, Streffer, J., Molinuevo, J. L., Popp, J., Bertram, L., Whiley, L., Maslen, L., Gomez-Romero, M., David, M., Lewis, M., Kurbatova, N., Ashton, N. J., Voyle, N., Kowalczyk, O., Martinez-Lage, P., Proitsi, P., Scheltens, P., Visser, P. J., Dobson, R. JB., Vandenberghe, R., Engelborghs, S., Vos, S. J. B., Snowden, S. G., Athersuch, T., Ashby, T., Kimhofer, T., Verachtert, W. & Lovestone, S., Jul 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P174-P175

    Research output: Contribution to journalMeeting abstract

  28. Study protocol for a randomised pragmatic trial comparing the clinical and cost effectiveness of Lithium and Quetiapine augmentation in treatment resistant Depression (the LQD study)

    Marwood, L., Taylor, R., Goldsmith, K., Romeo, R., Holland, R., Pickles, A., Hutchinson, J., Dietch, D., Cipriani, A., Nair, R., Attenburrow, M-J., Young, A. H., Geddes, J., McAllister-Williams, R. H. & Cleare, A. J., 26 Jun 2017, In : BMC Psychiatry. 17, 1, 231.

    Research output: Contribution to journalArticle

  29. HYdroxychloroquine to Improve Pregnancy Outcome in Women with AnTIphospholipid Antibodies (HYPATIA) Protocol: A Multinational Randomized Controlled Trial of Hydroxychloroquine versus Placebo in Addition to Standard Treatment in Pregnant Women with Antiphospholipid Syndrome or Antibodies

    Schreiber, K., Breen, K., Cohen, H., Jacobsen, S., Middeldorp, S., Pavord, S., Regan, L., Roccatello, D., Robinson, S. E., Sciascia, S., Seed, P. T., Watkins, L. & Hunt, B. J., 13 Jun 2017, In : Seminars in Thrombosis and Hemostasis.

    Research output: Contribution to journalArticle

  30. Lithium for long-term treatment of unipolar depression

    Young, A. H., 1 Jun 2017, In : The Lancet Psychiatry.

    Research output: Contribution to journalArticle

  31. Maternal BMI and diabetes in pregnancy: Investigating variations between ethnic groups using routine maternity data from London, UK

    Nishikawa, E., Oakley, L., Seed, P., Doyle, P. & Oteng-Ntim, E., 1 Jun 2017, In : PL o S One . 12, 6, e0179332.

    Research output: Contribution to journalArticle

  32. Modulation of Anxiety-Relevant Neural Circuits in Generalized Anxiety Disorder: A Novel Cholinergic System Pharmacotherapy Approach

    Young, A., Patrick, F., Wise, T., Meyer, N., Mazibuko, N., Oates, A. E., van der Bijl, A. M. H., Danjou, P., O'Connor, S., Doolin, E., Wooldridge, C., Macare, C., Williams, S. C. R., Perkins, A. & Young, A., 15 May 2017, In : Biological psychiatry. 81, 10, p. S70-S70

    Research output: Contribution to journalMeeting Abstract

  33. Biomarkers for depression: recent insights, current challenges and future prospects

    Strawbridge, R., Young, A. H. & Cleare, A. J., 10 May 2017, In : Neuropsychiatric Disease and Treatment . 2017, 13, p. 1245—1262 18 p.

    Research output: Contribution to journalReview article

  34. Mitochondrial genes are altered in blood early in Alzheimer's disease

    Lunnon, K., Keohane, A., Pidsley, R., Newhouse, S., Riddoch-Contreras, J., Thubron, E. B., Devall, M., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Schalkwyk, L., Dobson, R., Malik, A. N., Powell, J., Lovestone, S. & Hodges, A., 1 May 2017, In : Neurobiology of Aging. 53, p. 36-47 12 p.

    Research output: Contribution to journalArticle

  35. The dopamine hypothesis of Bipolar Affective Disorder: the state of the art and implications for treatment

    Ashok, A. H., Reis Marques, T. A., Jauhar, S., Nour, M., Goodwin, G. M., Young, A. & Howes, O. D., May 2017, In : Molecular Psychiatry. 22, 5, p. 666-679 14 p.

    Research output: Contribution to journalArticle

  36. 169 - Modulation of Anxiety-Relevant Neural Circuits in Generalized Anxiety Disorder: A Novel Cholinergic System Pharmacotherapy Approach: 72nd Annual Scientific Convention and Meeting

    Young, A., Patrick, F., Wise, T., Meyer, N., Mazibuko, N., Oates, A. E., van der Bijl, A. M. H., Danjou, P., O’Connor, S., Doolin, E., Wooldridge, C., Macare, C., Williams, S. CR. & Perkins, A., 29 Apr 2017, In : Biological psychiatry. 81, 10, Supplement, p. S70

    Research output: Contribution to journalArticle

  37. Erratum to “Analysing UK clinicians’ understanding of cognitive symptoms in major depression: A survey of primary care physicians and psychiatrists” [J. Affect. Disord. 207 (2017) 346–352]

    McAllister-Williams, R. H., Bones, K., Goodwin, G. M., Harrison, J., Katona, C., Rasmussen, J., Strong, S. & Young, A. H., 26 Apr 2017, In : Journal of Affective Disorders. 217, p. 306-307 2 p.

    Research output: Contribution to journalArticle

  38. Adapting to Stress: Understanding the Neurobiology of Resilience

    Osório, C., Probert, T., Jones, E., Young, A. H. & Robbins, I., 21 Apr 2017, In : Journal of Behavioural Medicine. 43, 4, p. 307-332 16 p.

    Research output: Contribution to journalReview article

  39. Pharmacological treatment of mixed states

    Cuomo, A., Nikolova, V. L., Yalin, N., Arnone, D., Fagiolini, A. & Young, A. H., 18 Apr 2017, In : CNS SPECTRUMS. 22, 2, p. 186-195 10 p.

    Research output: Contribution to journalArticle

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