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Research Outputs

  1. 2017
  2. Targeted neurogenesis pathway-based gene analysis identifies ADORA2A associated with hippocampal volume in mild cognitive impairment and Alzheimer's disease

    Horgusluoglu-Moloch, E., Nho, K., Risacher, S. L., Kim, S., Foroud, T., Shaw, L. M., Trojanowski, J. Q., Aisen, P. S., Petersen, R. C., Jack, C. R., Lovestone, S., Simmons, A., Weiner, M. W. & Saykin, A. J., 1 Dec 2017, In : Neurobiology of Aging. 60, p. 92-103 12 p.

    Research output: Contribution to journalArticle

  3. Intentional and unintentional medication non-adherence in psoriasis: the role of patients' medication beliefs and habit strength

    Thorneloe, R. J., Griffiths, C. E. M., Emsley, R., Ashcroft, D. M., Cordingley, L., BADBIR Study Group & PSORT study group, 26 Nov 2017, In : Journal of Investigative Dermatology.

    Research output: Contribution to journalArticle

  4. The Autism Family Experience Questionnaire (AFEQ): An ecologically-valid, parent-nominated measure of family experience, quality of life and prioritised outcomes for early intervention

    Leadbitter, K., Aldred, C., McConachie, H., Le Couteur, A., Charman, T., McDonald, W., Salomone, E., Emsley, R., Green, J. & The PACT Consortium, 18 Nov 2017, In : Journal of Autism and Developmental Disorders. p. 1-11

    Research output: Contribution to journalArticle

  5. Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study

    C Vieira, M., White, S. L., Patel, N., Seed, P. T., Briley, A. L., Sandall, J., Welsh, P., Sattar, N., Nelson, S. M., Lawlor, D. A., Poston, L., Pasupathy, D. & UPBEAT Consortium, 3 Nov 2017, In : BMC Medicine. 15, 1, p. 194

    Research output: Contribution to journalArticle

  6. SlowMo, a digital therapy targeting reasoning in paranoia, versus treatment as usual in the treatment of people who fear harm from others: Study protocol for a randomised controlled trial

    Garety, P. A., Ward, T., Freeman, D., Fowler, D., Emsley, R., Dunn, G., Kuipers, E., Bebbington, P., Waller, H., Greenwood, K., Greenwood, K., Rus-Calafell, M., Rus-Calafell, M., McGourty, A. & Hardy, A., 2 Nov 2017, In : Trials. 18, 1

    Research output: Contribution to journalArticle

  7. Client Perceptions of Helpfulness in Therapy: a Novel Video-Rating Methodology for Examining Process Variables at Brief Intervals During a Single Session

    Cocklin, A. A., Mansell, W., Emsley, R., McEvoy, P., Preston, C., Comiskey, J. & Tai, S., Nov 2017, In : Behavioural and Cognitive Psychotherapy. 45, 6, p. 647-660 14 p.

    Research output: Contribution to journalArticle

  8. Examining trends in type 2 diabetes incidence, prevalence and mortality in the UK between 2004 and 2014

    Zghebi, S. S., Steinke, D. T., Carr, M. J., Rutter, M. K., Emsley, R. A. & Ashcroft, D. M., Nov 2017, In : Diabetes, obesity & metabolism. 19, 11, p. 1537-1545 9 p.

    Research output: Contribution to journalArticle

  9. Perceptual control models of pursuit manual tracking demonstrate individual specificity and parameter consistency

    Parker, M. G., Tyson, S. F., Weightman, A. P., Abbott, B., Emsley, R. & Mansell, W., Nov 2017, In : Attention, perception & psychophysics. 79, 8, p. 2523-2537 15 p.

    Research output: Contribution to journalArticle

  10. DISCOVERY, REPLICATION AND EXTENSION STUDY OF PLASMA PROTEOMIC BIOMARKERS RELATING TO BRAIN AMYLOID BURDEN (CSF Aβ OR AMYLOID-PET) IN THE EMIF-AD BIOMARKER DISCOVERY COHORT: 2017 Abstract Supplement

    Westwood, S., Baird, A. L., Hye, A., Bos, I., Vos, S. J. B., Vandenberghe, R., Scheltens, P., Engelborghs, S., Frisoni, G. B., Molinuevo, J. L., Wallin, A., Lleó, A., Popp, J., Martinez-Lage, P., Snowden, S. G., Legido-Quigley, C., Bertram, L., Barkhof, F., Zetterberg, H., Streffer, J. & 2 others, Visser, P. J. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P361-P362

    Research output: Contribution to journalArticle

  11. PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY: 2017 Abstract Supplement

    Koychev, I. G., Gunn, R. N., Firouzian, A., Lawson, J., Zamboni, G., Ridha, B. H., Sahakian, B., Rowe, J. B., Thomas, A., Rochester, L., Ffytche, D., Howard, R. J., Zetterberg, H., MacKay, C. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P243

    Research output: Contribution to journalPoster abstract

  12. PET TAU AND AMYLOID-BETA DIFFER IN THEIR RELATIONSHIP TO AGE, COGNITION AND CSF BIOMARKERS IN MILD ALZHEIMER’S DISEASE: AN OBSERVATIONAL STUDY: 2017 Abstract Supplement

    Koychev, I. G., Gunn, R. N., Firouzian, A., Lawson, J., Zamboni, G., Ridha, B. H., Sahakian, B., Rowe, J. B., Thomas, A., Rochester, L., Ffytche, D., Howard, R. J., Zetterberg, H., MacKay, C. & Lovestone, S., 20 Oct 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P456-P457

    Research output: Contribution to journalPoster abstract

  13. Amyloid beta synaptotoxicity is Wnt–planar cell polarity dependent and blocked by fasudil

    Sellers, K. J., Elliott, C., Jackson, J., Ghosh, A., Ribe, E., Rojo-Sanchís, A., Jarosz-Griffiths, H. H., Watson, I. A., Xia, W., Semenov, M., Morin, P., Hooper, N. M., Porter, R., Preston, J., Al-Shawi, R., Baillie, G., Lovestone, S., Cuadrado, A., Harte, M., Simons, P. & 2 others, Srivastava, D. P. & Killick, R., 19 Oct 2017, In : Alzheimer's & Dementia.

    Research output: Contribution to journalArticle

  14. The role of cognitive and metacognitive factors in non-clinical paranoia and negative affect

    Sellers, R., Emsley, R., Wells, A. & Morrison, A. P., 5 Oct 2017, In : Psychology and Psychotherapy: Theory, Research and Practice.

    Research output: Contribution to journalArticle

  15. The effects of improving sleep on mental health (OASIS): a randomised controlled trial with mediation analysis

    Freeman, D., Sheaves, B., Goodwin, G. M., Yu, L-M., Nickless, A., Harrison, P. J., Emsley, R., Luik, A. I., Foster, R. G., Wadekar, V., Hinds, C., Gumley, A., Jones, R., Lightman, S., Jones, S., Bentall, R., Kinderman, P., Rowse, G., Brugha, T., Blagrove, M. & 22 others, Gregory, A. M., Fleming, L., Walklet, E., Glazebrook, C., Davies, E. B., Hollis, C., Haddock, G., John, B., Coulson, M., Fowler, D., Pugh, K., Cape, J., Moseley, P., Brown, G., Hughes, C., Obonsawin, M., Coker, S., Watkins, E., Schwannauer, M., MacMahon, K., Siriwardena, A. N. & Espie, C. A., Oct 2017, In : The Lancet Psychiatry. 4, 10, p. 749-758 10 p.

    Research output: Contribution to journalArticle

  16. Hormone-secreting adrenal tumours cause severe hypertension and high rates of poor pregnancy outcome: a UKOSS study with case control comparisons

    Quartermaine, G., Lambert, K., Rees, K., Seed, P. T., Dhanjal, M. K., Knight, M., McCance, D. R. & Williamson, C., 5 Sep 2017, In : BJOG.

    Research output: Contribution to journalArticle

  17. Watch-and-wait approach for rectal cancer: concepts of a subject-specific method

    Renehan, A. G., Malcomson, L. & Emsley, R., Sep 2017, In : The Lancet Gastroenterology & Hepatology. 2, 9, p. 627

    Research output: Contribution to journalArticle

  18. OP 2 Placental growth factor informed management of suspected pre-eclampsia and/or fetal growth restriction: The MAPPLE cohort study

    Sharp, A., Chappell, L., Dekker, G., Pelletier, S., Garnier, Y., Zeren, O., Hillerer, K. M., Fischer, T., Seed, P., Turner, M., Shennan, A. & Alfirevic, Z., 12 Aug 2017, In : Pregnancy Hypertension. 9, p. 9-10 2 p.

    Research output: Contribution to journalMeeting abstract

  19. Disrupting Sleep: The Effects of Sleep Loss on Psychotic Experiences Tested in an Experimental Study With Mediation Analysis

    Reeve, S., Emsley, R., Sheaves, B. & Freeman, D., 4 Aug 2017, In : Schizophrenia Bulletin.

    Research output: Contribution to journalArticle

  20. Metabolic profiling of gestational diabetes in obese women during pregnancy

    White, S. L., Pasupathy, D., Sattar, N., Nelson, S. M., Lawlor, D. A., Briley, A. L., Seed, P. T., Welsh, P., Poston, L. & UPBEAT Consortium, 1 Aug 2017, In : Diabetologia. 60, 10, p. 1603-1912 10 p.

    Research output: Contribution to journalArticle

  21. EXPLORING THE RELATIONSHIP BETWEEN ANAEMIA AND ALZHEIMER’S DISEASE: 2017 Abstract Supplement

    Winchester, L., Nevado-Holgado, A. J. & Lovestone, S., 20 Jul 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P221

    Research output: Contribution to journalMeeting abstract

  22. NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology

    Rojo, A. I., Pajares, M., Rada, P., Nuñez, A., Nevado-Holgado, A. J., Killik, R., Van Leuven, F., Ribe, E., Lovestone, S., Yamamoto, M. & Cuadrado, A., 5 Jul 2017, In : Redox Biology.

    Research output: Contribution to journalArticle

  23. DISCOVERY AND VALIDATION OF MULTIMODAL BIOMARKER SIGNATURES RELATING TO ALZHEIMER'S DISEASE PATHOLOGY AND PROGRESSION: 2017 Abstract Supplement

    Westwood, S., Hye, A., Lleó, A., Nevado-Holgado, A. J., Baird, A. L., Wallin, A., Leslie, A., Jimenez, B., Liu, B. Y., Legido-Quigley, C., Dima, D., Ruvolo, D., Holmes, E., D'Hondt, E., Westman, E., Barkhof, F., Frisoni, G. B., Zetterberg, H., Bos, I., Pearce, J. & 27 others, Streffer, J., Molinuevo, J. L., Popp, J., Bertram, L., Whiley, L., Maslen, L., Gomez-Romero, M., David, M., Lewis, M., Kurbatova, N., Ashton, N. J., Voyle, N., Kowalczyk, O., Martinez-Lage, P., Proitsi, P., Scheltens, P., Visser, P. J., Dobson, R. JB., Vandenberghe, R., Engelborghs, S., Vos, S. J. B., Snowden, S. G., Athersuch, T., Ashby, T., Kimhofer, T., Verachtert, W. & Lovestone, S., Jul 2017, In : Alzheimer's & Dementia. 13, 7, Supplement, p. P174-P175

    Research output: Contribution to journalMeeting abstract

  24. Effects of digital Cognitive Behavioural Therapy for Insomnia on cognitive function: study protocol for a randomised controlled trial

    Kyle, S. D., Hurry, M. E. D., Emsley, R., Luik, A. I., Omlin, X., Spiegelhalder, K., Espie, C. A. & Sexton, C. E., 17 Jun 2017, In : Trials. 18, 1, p. 281

    Research output: Contribution to journalArticle

  25. HYdroxychloroquine to Improve Pregnancy Outcome in Women with AnTIphospholipid Antibodies (HYPATIA) Protocol: A Multinational Randomized Controlled Trial of Hydroxychloroquine versus Placebo in Addition to Standard Treatment in Pregnant Women with Antiphospholipid Syndrome or Antibodies

    Schreiber, K., Breen, K., Cohen, H., Jacobsen, S., Middeldorp, S., Pavord, S., Regan, L., Roccatello, D., Robinson, S. E., Sciascia, S., Seed, P. T., Watkins, L. & Hunt, B. J., 13 Jun 2017, In : Seminars in Thrombosis and Hemostasis.

    Research output: Contribution to journalArticle

  26. Choosing the target difference ('effect size') for a randomised controlled trial - DELTA2 guidance protocol

    Cook, J. A., Julious, S. A., Sones, W., Rothwell, J. C., Ramsay, C. R., Hampson, L. V., Emsley, R., Walters, S. J., Hewitt, C., Bland, M., Fergusson, D. A., Berlin, J. A., Altman, D. & Vale, L. D., 12 Jun 2017, In : Trials. 18, 1, p. 271

    Research output: Contribution to journalArticle

  27. Maternal BMI and diabetes in pregnancy: Investigating variations between ethnic groups using routine maternity data from London, UK

    Nishikawa, E., Oakley, L., Seed, P., Doyle, P. & Oteng-Ntim, E., 1 Jun 2017, In : PL o S One . 12, 6, e0179332.

    Research output: Contribution to journalArticle

  28. Debt Counselling for Depression in Primary Care: an adaptive randomised controlled pilot trial (DeCoDer study)

    Gabbay, M. B., Ring, A., Byng, R., Anderson, P., Taylor, R. S., Matthews, C., Harris, T., Berry, V., Byrne, P., Carter, E., Clarke, P., Cocking, L., Edwards, S., Emsley, R., Fornasiero, M., Frith, L., Harris, S., Huxley, P., Jones, S., Kinderman, P. & 14 others, King, M., Kosnes, L., Marshall, D., Mercer, D., May, C., Nolan, D., Phillips, C., Rawcliffe, T., Sardani, A. V., Shaw, E., Thompson, S., Vickery, J., Wainman, B. & Warner, M., Jun 2017, 35 ed. NIHR Health Technology Assessment Programme. 192 p.

    Research output: Book/ReportReport

  29. Comparing early signs and basic symptoms as methods for predicting psychotic relapse in clinical practice

    Eisner, E., Drake, R., Lobban, F., Bucci, S., Emsley, R. & Barrowclough, C., 9 May 2017, In : Schizophrenia Research.

    Research output: Contribution to journalArticle

  30. Mitochondrial genes are altered in blood early in Alzheimer's disease

    Lunnon, K., Keohane, A., Pidsley, R., Newhouse, S., Riddoch-Contreras, J., Thubron, E. B., Devall, M., Soininen, H., Kłoszewska, I., Mecocci, P., Tsolaki, M., Vellas, B., Schalkwyk, L., Dobson, R., Malik, A. N., Powell, J., Lovestone, S. & Hodges, A., 1 May 2017, In : Neurobiology of Aging. 53, p. 36-47 12 p.

    Research output: Contribution to journalArticle

  31. Autism spectrum disorder and other neurobehavioural comorbidities in rare disorders of the Ras/MAPK pathway

    Garg, S., Brooks, A., Burns, A., Burkitt-Wright, E., Kerr, B., Huson, S., Emsley, R. & Green, J., May 2017, In : Developmental Medicine and Child Neurology. 59, 5, p. 544-549 6 p.

    Research output: Contribution to journalArticle

  32. #WhyWeTweetMH: Understanding Why People Use Twitter to Discuss Mental Health Problems

    Berry, N., Lobban, F., Belousov, M., Emsley, R., Nenadic, G. & Bucci, S., 5 Apr 2017, In : Journal of Medical Internet Research. 19, 4, 13 p., e107.

    Research output: Contribution to journalArticle

  33. Effect of reproductive ageing on pregnant mouse uterus and cervix

    Patel, R., Moffatt, J. D., Mourmoura, E., Demaison, L., Seed, P. T., Poston, L. & Tribe, R. M., 15 Mar 2017, In : The Journal of physiology. 595, 6, p. 2065–2084

    Research output: Contribution to journalArticle

  34. Predictors of Nightly Subjective-Objective Sleep Discrepancy in Poor Sleepers over a Seven-Day Period

    Herbert, V., Pratt, D., Emsley, R. & Kyle, S. D., 9 Mar 2017, In : Brain Sciences. 7, 3

    Research output: Contribution to journalArticle

  35. Life Expectancy and Cause-Specific Mortality in Type 2 Diabetes: A Population-Based Cohort Study Quantifying Relationships in Ethnic Subgroups

    Wright, A. K., Kontopantelis, E., Emsley, R., Buchan, I., Sattar, N., Rutter, M. K. & Ashcroft, D. M., Mar 2017, In : Diabetes Care. 40, 3, p. 338-345 8 p.

    Research output: Contribution to journalArticle

  36. Predictors and mediators of trait anger across the psychosis continuum: The role of attachment style, paranoia and social cognition

    Darrell-Berry, H., Bucci, S., Palmier-Claus, J., Emsley, R., Drake, R. & Berry, K., Mar 2017, In : Psychiatry Research. 249, p. 132-138 7 p.

    Research output: Contribution to journalArticle

  37. Reply: Rapid changes in practice make analysis of historical databases irrelevant for contemporary counselling

    Sunkara, S. K., Lamarca, A., Polyzos, N. P., Seed, P. T. & Khalaf, Y., 25 Feb 2017, In : Human reproduction (Oxford, England). 32, 4, p. 964-965 2 p.

    Research output: Contribution to journalArticle

  38. Infant adiposity following a randomised controlled trial of a behavioural intervention in obese pregnancy

    Patel, N., Godfrey, K. M., Pasupathy, D., Levin, J., Flynn, A. C., Hayes, L., Briley, A. L., Bell, R., Lawlor, D. A., Oteng-Ntim, E., Nelson, S. M., Robson, S. C., Sattar, N., Singh, C., Wardle, J., White, S., Seed, P. T. & Poston, L., 20 Feb 2017, In : International Journal of Obesity.

    Research output: Contribution to journalArticle

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