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Research Outputs

  1. 2018
  2. Myocardial NADPH oxidase-4 regulates the physiological response to acute exercise

    Hancock, M., Hafstad, A. D., Nabeebaccus, A. A., Catibog, N., Logan, A., Smyrnias, I., Hansen, S. S., Lanner, J., Schröder, K., Murphy, M. P., Shah, A. M. & Zhang, M., 27 Dec 2018, In : eLife. 7

    Research output: Contribution to journalArticle

  3. Rationale & design of the PROMISES study: A prospective assessment and validation study of salivary progesterone as a test for preterm birth in pregnant women from rural India

    Sharma, P., Khan, S., Ghule, M., Shivkumar, V. B., Dargan, R., Seed, P. T., Sarkar, A., Mehra, S., Shivkumar, P. V. & Tribe, R. M., 22 Dec 2018, In : Reproductive Health. 15, 1, 215.

    Research output: Contribution to journalArticle

  4. Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

    Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Coleman, J. R. I., Eley, T. C., Gaspar, H. A., McGuffin, P., Mullins, N., O'Reilly, P. F., Lewis, C. M. & Breen, G., 20 Dec 2018, In : PLoS ONE. 13, 12, e0209160.

    Research output: Contribution to journalArticle

  5. Telomere length as a predictor of emotional processing in the brain

    Powell, T. R., De Jong, S., Breen, G., Lewis, C. M. & Dima, D., 4 Dec 2018, In : Human Brain Mapping.

    Research output: Contribution to journalArticle

  6. Extremely rare variants reveal patterns of germline mutation rate heterogeneity in humans

    The BRIDGES Consortium, 1 Dec 2018, In : Nature Communications. 9, 1, 3753.

    Research output: Contribution to journalArticle

  7. Genes associated with anhedonia: a new analysis in a large clinical trial (GENDEP)

    Ren, H., Fabbri, C., Uher, R., Rietschel, M., Mors, O., Henigsberg, N., Hauser, J., Zobel, A., Maier, W., Dernovsek, M. Z., Souery, D., Cattaneo, A., Breen, G., Craig, I. W., Farmer, A. E., McGuffin, P., Lewis, C. M. & Aitchison, K. J., 1 Dec 2018, In : Translational psychiatry. 8, 1, 150.

    Research output: Contribution to journalArticle

  8. Polygenic risk score analyses of symptoms and treatment response in an antipsychotic-naive first episode of psychosis cohort

    Santoro, M. L., Ota, V., de Jong, S., Noto, C., Spindola, L. M., Talarico, F., Gouvea, E., Lee, S. H., Moretti, P., Curtis, C., Patel, H., Newhouse, S., Carvalho, C. M., Gadelha, A., Cordeiro, Q., Bressan, R. A., Belangero, S. I. & Breen, G., 1 Dec 2018, In : Translational psychiatry. 8, 1, 174.

    Research output: Contribution to journalArticle

  9. Inhibition of Pro-Fibrotic MicroRNA-21 Affects Platelets and their Releasate

    Barwari, T., Eminaga, S., Mayr, U., Lu, R., Armstrong, P. C., Chan, M. V., Sahraei, M., Fernandez-Fuertes, M., Moreau, T., Barallobre-Barreiro, J., Lynch, M., Yin, X., Schulte, C., Baig, F., Pechlaner, R., Langley, S. R., Zampetaki, A., Santer, P., Weger, M., Plasenzotti, R. & 10 others, Schosserer, M., Grillari, J., Kiechl, S., Willeit, J., Shah, A. M., Ghevaert, C., Warner, T. D., Fernández-Hernando, C., Suárez, Y. & Mayr, M., 2 Nov 2018, In : JCI Insight.

    Research output: Contribution to journalArticle

  10. Epigenetics in eating disorders: a systematic review

    Hübel, C., Marzi, S. J., Breen, G. & Bulik, C. M., 23 Oct 2018, In : Molecular Psychiatry.

    Research output: Contribution to journalReview article

  11. The impact of ethnicity on adverse perinatal outcome in women with chronic hypertension: a cohort study

    Webster, L. M., Bramham, K., Seed, P. T., Homsy, M., Widdows, K., Webb, A. J., Nelson-Piercy, C., Magee, L., Thilaganathan, B., Myers, J. E. & Chappell, L. C., 14 Oct 2018, In : Ultrasound in Obstetrics and Gynecology.

    Research output: Contribution to journalArticle

  12. Retrotransposons in the development and progression of amyotrophic lateral sclerosis

    Savage, A. L., Schumann, G. G., Breen, G., Bubb, V. J., Al-Chalabi, A. & Quinn, J. P., 10 Oct 2018, In : Journal of Neurology, Neurosurgery and Psychiatry.

    Research output: Contribution to journalArticle

  13. Conference Report: Psychiatric Genomics Consortium Meeting: Pathways to Drugs, London, March 2017

    Gaspar, H. A., Collier, D. A., Geschwind, D. H., Lewis, C. M., Li, Q., Roth, B. L., Sullivan, P. F. & Breen, G., 15 Sep 2018, In : Biological psychiatry. 84, 6, p. e49-e50

    Research output: Contribution to journalArticle

  14. A Slow-Digesting, Low-Glycemic Load Nutritional Beverage Improves Glucose Tolerance in Obese Pregnant Women Without Gestational Diabetes

    Maitland, R., Patel, N., Barr, S., Sherry, C., Marriage, B., Seed, P., Fernandez, L. G., Pedrosa, J. M. L., Murphy, H., Rueda, R. & Poston, L., 11 Sep 2018, In : Diabetes Technology and Therapeutics. 20, 10, p. 672-680 9 p.

    Research output: Contribution to journalArticle

  15. Examination of the shared genetic basis of anorexia nervosa and obsessive–compulsive disorder

    Eating Disorders Working Group of the Psychiatric Genomics Consortium, Tourette Syndrome/Obsessive–Compulsive Disorder Working Group of the Psychiatric Genomics Consortium, 7 Aug 2018, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  16. Biochemistry and physiology of cardiac muscle

    Nabeebaccus, A. & Shah, A. M., Aug 2018, In : Medicine (United Kingdom). 46, 8, p. 431-436 6 p.

    Research output: Contribution to journalReview article

  17. Creating biobanks in low and middle-income countries to improve knowledge: The PREPARE initiative

    De Oliveira, L., Dias, M. A. B., Jeyabalan, A., Payne, B., Redman, C. W., Magee, L., Poston, L., Chappell, L., Seed, P., von Dadelszen, P. & Roberts, J. M., Jul 2018, In : Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health. 13, p. 62-64 3 p.

    Research output: Contribution to journalArticle

  18. Gestational diabetes modifies the association between PlGF in early pregnancy and preeclampsia in women with obesity

    Vieira, M. C., Begum, S., Seed, P. T., Badran, D., Briley, A. L., Gill, C., Godfrey, K. M., Lawlor, D. A., Nelson, S. M., Patel, N., Sattar, N., White, S. L., Poston, L., Pasupathy, D. & UPBEAT Consortium, Jul 2018, In : Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health. 13, p. 267-272

    Research output: Contribution to journalArticle

  19. Rigor and reproducibility in genetic research on eating disorders

    Hübel, C., Leppä, V., Breen, G. & Bulik, C. M., Jul 2018, In : The International journal of eating disorders. 51, 7, p. 593-607 15 p.

    Research output: Contribution to journalReview article

  20. Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies

    Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Lee, S-H., Newhouse, S., Patel, H., O'Donovan, M., Lewis, G., Jenkins, G., Weinshilboum, R. M., Farmer, A. & 7 others, Aitchison, K. J., Craig, I., McGuffin, P., Schruers, K., Biernacka, J. M., Uher, R. & Lewis, C. M., 28 Jun 2018, In : European Neuropsychopharmacology.

    Research output: Contribution to journalArticle

  21. Biochemistry and physiology of cardiac muscle

    Nabeebaccus, A. & Shah, A. M., 23 Jun 2018, In : Medicine. 42, 8, p. 413-417 5 p.

    Research output: Contribution to journalArticle

  22. Analysis of shared heritability in common disorders of the brain

    Brainstorm Consortium, 22 Jun 2018, In : Science. 360, 6395

    Research output: Contribution to journalArticle

  23. A Meta-Analysis of Cytokine Concentrations in Eating Disorders

    Dalton, B., Bartholdy, S., Robinson, L., Solmi, M., Ibrahim, M. A. A., Breen, G. D., Schmidt, U. H. & Himmerich, H., 7 Jun 2018, In : Journal of Psychiatric Research.

    Research output: Contribution to journalArticle

  24. Modelling the complexity of heart failure with preserved ejection fraction

    O'Gallagher, K. & Shah, A. M., 1 Jun 2018, In : Cardiovascular Research. 114, 7, p. 919-921

    Research output: Contribution to journalEditorial

  25. Interpregnancy weight change and adverse pregnancy outcomes: A systematic review and meta-analysis

    Oteng-Ntim, E., Mononen, S., Sawicki, O., Seed, P. T., Bick, D. & Poston, L., Jun 2018, In : BMJ open. 8, 6, 14 p., e018778.

    Research output: Contribution to journalReview article

  26. New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

    Fabbri, C., Tansey, K., Perlis, R., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Sang-Hyuk, L., Newhouse, S., Patel, H., Guipponi, M., Perroud, N., Bondolfi, G., O'Donovan, M., Lewis, G. & 8 others, Biernacka, J., Weinshilboum, R., Farmer, A., Aitchison, K., Craig, I., McGuffin, P., Uher, R. & Lewis, C., 22 May 2018, In : The pharmacogenomics journal. 18, p. 413-421

    Research output: Contribution to journalArticle

  27. Correction to: Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa (Molecular Psychiatry, (2018), 23, 5, (1169-1180), 10.1038/mp.2017.88)

    MCT Slof-Op ’t Landt & Eating Disorder Working Group of the Psychiatric Genomics Consortium, 1 May 2018, In : Molecular Psychiatry. 23, 9

    Research output: Contribution to journalComment/debate

  28. Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

    The Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S-A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J. & 32 others, Cai, N., Castelao, E., Christensen, J. H., Clarke, T., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Eley, T. C., Gaspar, H. A., Hansen, T. F., Li, Y., Mcguffin, P., Mill, J., Mullins, N., Purcell, S. M., Riley, B. P., Smith, D. J., Tansey, K. E., Traylor, M., Uher, R., Lewis, C. M., Breen, G. & O'Reilly, P. F., 1 May 2018, In : Nature Genetics. 50, 5, p. 668-681

    Research output: Contribution to journalArticle

  29. Mental health in UK Biobank: Development, implementation and results from an online questionnaire completed by 157 366 participants

    Davis, K. A. S., Coleman, J. R. I., Adams, M., Allen, N., Breen, G., Cullen, B., Dickens, C., Fox, E., Graham, N., Holliday, J., Howard, L. M., John, A., Lee, W., McCabe, R., McIntosh, A., Pearsall, R., Smith, D. J., Sudlow, C., Ward, J., Zammit, S. & 1 others, Hotopf, M., 1 May 2018, In : BJPsych Open. 4, 3, p. 83-90 8 p.

    Research output: Contribution to journalArticle

  30. A genome-wide association study for extremely high intelligence

    Zabaneh, D., Krapohl, E., Gaspar, H. A., Curtis, C. J., Lee, S. H., Patel, H., Newhouse, S., Simpson, M. A., Putallaz, M., Lubinski, D., Plomin, R. & Breen, G., May 2018, In : Molecular Psychiatry. 23, 5, p. 1226–1232

    Research output: Contribution to journalArticle

  31. Evaluation of a novel vital sign device to reduce maternal mortality and morbidity in low-resource settings: a mixed method feasibility study for the CRADLE-3 trial

    Vousden, N., Lawley, E., Nathan, H. L., Seed, P. T., Brown, A., Muchengwa, T., Charantimath, U., Bellad, M., Gidiri, M. F., Goudar, S., Chappell, L. C., Sandall, J., Shennan, A. H. & CRADLE Trial Collaborative Group, 27 Apr 2018, In : BMC Pregnancy and Childbirth. 18, 1, 115.

    Research output: Contribution to journalArticle

  32. Addendum: Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

    Howard, D. M., Adams, M. J., Shirali, M., Clarke, T. K., Marioni, R. E., Davies, G., Coleman, J. R. I., Alloza, C., Shen, X., Barbu, M. C., Wigmore, E. M., Gibson, J., Hagenaars, S. P., Lewis, C. M., Ward, J., Smith, D. J., Sullivan, P. F., Haley, C. S., Breen, G., Deary, I. J. & 1 others, McIntosh, A. M., 16 Apr 2018, In : Nature Communications. 9, 1, p. 1-3 1 p.

    Research output: Contribution to journalArticle

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