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Research Outputs

  1. 2018
  2. Rationale & design of the PROMISES study: A prospective assessment and validation study of salivary progesterone as a test for preterm birth in pregnant women from rural India

    Sharma, P., Khan, S., Ghule, M., Shivkumar, V. B., Dargan, R., Seed, P. T., Sarkar, A., Mehra, S., Shivkumar, P. V. & Tribe, R. M., 22 Dec 2018, In : Reproductive Health. 15, 1, 215.

    Research output: Contribution to journalArticle

  3. Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

    Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Coleman, J. R. I., Eley, T. C., Gaspar, H. A., McGuffin, P., Mullins, N., O'Reilly, P. F., Lewis, C. M. & Breen, G., 20 Dec 2018, In : PLoS ONE. 13, 12, e0209160.

    Research output: Contribution to journalArticle

  4. Telomere length as a predictor of emotional processing in the brain

    Powell, T. R., De Jong, S., Breen, G., Lewis, C. M. & Dima, D., 4 Dec 2018, In : Human Brain Mapping.

    Research output: Contribution to journalArticle

  5. Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder

    Major Depressive Disorder and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, 1 Dec 2018, In : Communications Biology. 1, 1, 163.

    Research output: Contribution to journalArticle

  6. Genes associated with anhedonia: a new analysis in a large clinical trial (GENDEP)

    Ren, H., Fabbri, C., Uher, R., Rietschel, M., Mors, O., Henigsberg, N., Hauser, J., Zobel, A., Maier, W., Dernovsek, M. Z., Souery, D., Cattaneo, A., Breen, G., Craig, I. W., Farmer, A. E., McGuffin, P., Lewis, C. M. & Aitchison, K. J., 1 Dec 2018, In : Translational psychiatry. 8, 1, 150.

    Research output: Contribution to journalArticle

  7. Algorithms for left atrial wall segmentation and thickness – Evaluation on an open-source CT and MRI image database

    Karim, R., Blake, L-E., Inoue, J., Tao, Q., Jia, S., Housden, R. J., Bhagirath, P., Duval, J-L., Varela, M., Behar, J., Cadour, L., van der Geest, R. J., Cochet, H., Drangova, M., Sermesant, M., Razavi, R., Aslanidi, O., Rajani, R. & Rhode, K., Dec 2018, In : Medical Image Analysis. 50, p. 36-53 18 p.

    Research output: Contribution to journalArticle

  8. Genome-wide association study of treatment-resistance in depression and meta-analysis of three independent samples

    Fabbri, C., Kasper, S., Kautzky, A., Bartova, L., Dold, M., Zohar, J., Souery, D., Montgomery, S., Albani, D., Raimondi, I., Dikeos, D., Rujescu, D., Uher, R., Lewis, C. M., Mendlewicz, J. & Serretti, A., 23 Nov 2018, In : British Journal of Psychiatry. 214, 1, p. 36-41

    Research output: Contribution to journalArticle

  9. Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders

    O'Brien, H. E., Hannon, E., Hill, M. J., Toste, C. C., Robertson, M. J., Morgan, J. E., McLaughlin, G., Lewis, C. M., Schalkwyk, L. C., Hall, L. S., Pardiñas, A. F., Owen, M. J., O'Donovan, M. C., Mill, J. & Bray, N. J., 12 Nov 2018, In : Genome Biology. 19, 1, 1 p.

    Research output: Contribution to journalArticle

  10. Patient-specific modeling of right coronary circulation vulnerability post-liver transplant in Alagille’s syndrome

    Silva Vieira, M., Arthurs, C. J., Hussain, T., Razavi, R. & Figueroa, C. A., 8 Nov 2018, In : PLoS ONE. 13, 11, e0205829.

    Research output: Contribution to journalArticle

  11. Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans

    Hanscombe, K. B., Morris, D. L., Noble, J. A., Dilthey, A. T., Tombleson, P., Kaufman, K. M., Comeau, M., Langefeld, C. D., Alarcon-Riquelme, M. E., Gaffney, P. M., Jacob, C. O., Sivils, K. L., Tsao, B. P., Alarcon, G. S., Brown, E. E., Croker, J., Edberg, J., Gilkeson, G., James, J. A., Kamen, D. L. & 16 others, Kelly, J. A., McCune, J., Merrill, J. T., Petri, M., Ramsey-Goldman, R., Reveille, J. D., Salmon, J. E., Scofield, H., Utset, T., Wallace, D. J., Weisman, M. H., Kimberly, R. P., Harley, J. B., Lewis, C. M., Criswell, L. A. & Vyse, T. J., 1 Nov 2018, In : Human Molecular Genetics. 27, 21, p. 3813-3824 12 p., 27(21).

    Research output: Contribution to journalArticle

  12. The impact of ethnicity on adverse perinatal outcome in women with chronic hypertension: a cohort study

    Webster, L. M., Bramham, K., Seed, P. T., Homsy, M., Widdows, K., Webb, A. J., Nelson-Piercy, C., Magee, L., Thilaganathan, B., Myers, J. E. & Chappell, L. C., 14 Oct 2018, In : Ultrasound in Obstetrics and Gynecology.

    Research output: Contribution to journalArticle

  13. Mind the gap: quantification of incomplete ablation patterns after pulmonary vein isolation using minimum path search

    Nuñez-Garcia, M., Camara, O., O’Neill, M. D., Razavi, R., Chubb, H. & Butakoff, C., 10 Oct 2018, In : Medical Image Analysis.

    Research output: Contribution to journalArticle

  14. Transdiagnostic dimensions of psychopathology at first episode psychosis: findings from the multinational EU-GEI study

    Quattrone, D., Di Forti, M., Gayer-Anderson, C., Ferraro, L., Jongsma, H. E., Tripoli, G., La Cascia, C., La Barbera, D., Tarricone, I., Berardi, D., EU-GEI WP2 Group, Szöke, A., Arango, C., Lasalvia, A., Tortelli, A., Llorca, P-M., de Haan, L., Velthorst, E., Bobes, J., Bernardo, M. & 18 others, Sanjuán, J., Santos, J. L., Arrojo, M., Del-Ben, C. M., Menezes, P. R., Selten, J-P., Jones, P. B., Kirkbride, J. B., Richards, A. L., O'Donovan, M. C., Sham, P. C., Vassos, E., Rutten, B. P., van Os, J., Morgan, C., Lewis, C. M., Murray, R. M. & Reininghaus, U., 4 Oct 2018, In : Psychological Medicine. p. 1-14 14 p.

    Research output: Contribution to journalArticle

  15. Conference Report: Psychiatric Genomics Consortium Meeting: Pathways to Drugs, London, March 2017

    Gaspar, H. A., Collier, D. A., Geschwind, D. H., Lewis, C. M., Li, Q., Roth, B. L., Sullivan, P. F. & Breen, G., 15 Sep 2018, In : Biological psychiatry. 84, 6, p. e49-e50

    Research output: Contribution to journalArticle

  16. A Slow-Digesting, Low-Glycemic Load Nutritional Beverage Improves Glucose Tolerance in Obese Pregnant Women Without Gestational Diabetes

    Maitland, R., Patel, N., Barr, S., Sherry, C., Marriage, B., Seed, P., Fernandez, L. G., Pedrosa, J. M. L., Murphy, H., Rueda, R. & Poston, L., 11 Sep 2018, In : Diabetes Technology and Therapeutics. 20, 10, p. 672-680 9 p.

    Research output: Contribution to journalArticle

  17. Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders

    Genetic Risk and Outcome of Psychosis (GROUP) consortium, Sep 2018, In : The British journal of psychiatry : the journal of mental science. 213, 3, p. 535-541 7 p.

    Research output: Contribution to journalArticle

  18. Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases

    Chen, J. A., Chen, Z., Won, H., Huang, A. Y., Lowe, J. K., Wojta, K., Yokoyama, J. S., Bensimon, G., Leigh, P. N., Payan, C., Shatunov, A., Jones, A. R., Lewis, C. M., Deloukas, P., Amouyel, P., Tzourio, C., Dartigues, J. F., Ludolph, A., Boxer, A. L., Bronstein, J. M. & 3 others, Al-Chalabi, A., Geschwind, D. H. & Coppola, G., 8 Aug 2018, In : Molecular Neurodegeneration. 13, 1, 41.

    Research output: Contribution to journalArticle

  19. Genetic disposition to inflammation and response to antidepressants in major depressive disorder

    Zwicker, A., Fabbri, C., Rietschel, M., Hauser, J., Mors, O., Maier, W., Zobel, A., Farmer, A., Aitchison, K. J., McGuffin, P., Lewis, C. M. & Uher, R., 7 Aug 2018, In : Journal of psychiatric research.

    Research output: Contribution to journalArticle

  20. Creating biobanks in low and middle-income countries to improve knowledge: The PREPARE initiative

    De Oliveira, L., Dias, M. A. B., Jeyabalan, A., Payne, B., Redman, C. W., Magee, L., Poston, L., Chappell, L., Seed, P., von Dadelszen, P. & Roberts, J. M., Jul 2018, In : Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health. 13, p. 62-64 3 p.

    Research output: Contribution to journalArticle

  21. Gestational diabetes modifies the association between PlGF in early pregnancy and preeclampsia in women with obesity

    Vieira, M. C., Begum, S., Seed, P. T., Badran, D., Briley, A. L., Gill, C., Godfrey, K. M., Lawlor, D. A., Nelson, S. M., Patel, N., Sattar, N., White, S. L., Poston, L., Pasupathy, D. & UPBEAT Consortium, Jul 2018, In : Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health. 13, p. 267-272

    Research output: Contribution to journalArticle

  22. Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies

    Fabbri, C., Tansey, K. E., Perlis, R. H., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Lee, S-H., Newhouse, S., Patel, H., O'Donovan, M., Lewis, G., Jenkins, G., Weinshilboum, R. M., Farmer, A. & 7 others, Aitchison, K. J., Craig, I., McGuffin, P., Schruers, K., Biernacka, J. M., Uher, R. & Lewis, C. M., 28 Jun 2018, In : European Neuropsychopharmacology.

    Research output: Contribution to journalArticle

  23. Analysis of shared heritability in common disorders of the brain

    Brainstorm Consortium, 22 Jun 2018, In : Science. 360, 6395

    Research output: Contribution to journalArticle

  24. In Vivo Molecular Characterization of Abdominal Aortic Aneurysms Using Fibrin-Specific Magnetic Resonance Imaging

    Botnar, R. M., Brangsch, J., Reimann, C., Janssen, C. H. P., Razavi, R., Hamm, B. & Makowski, M. R., 5 Jun 2018, In : Journal of the American Heart Association. 7, 11

    Research output: Contribution to journalArticle

  25. Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes (Nature Genetics, (2018), 50, 4, (524-537), 10.1038/s41588-018-0058-3)

    AFGen Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, International Genomics of Blood Pressure (iGEN-BP) Consortium, INVENT Consortium, STARNET, BioBank Japan Cooperative Hospital Group, COMPASS Consortium, EPIC-CVD Consortium, EPIC-InterAct Consortium, International Stroke Genetics Consortium (ISGC), METASTROKE Consortium, Neurology Working Group of the CHARGE Consortium, NINDS Stroke Genetics Network (SiGN), UK Young Lacunar DNA Study & MEGASTROKE Consortium, 3 Jun 2018, In : Nature Genetics.

    Research output: Contribution to journalComment/debate

  26. MR-guided Cardiac Interventions

    Pushparajah, K., Chubb, H. & Razavi, R., 1 Jun 2018, In : Topics in magnetic resonance imaging : TMRI. 27, 3, p. 115-128 14 p.

    Research output: Contribution to journalArticle

  27. Interpregnancy weight change and adverse pregnancy outcomes: A systematic review and meta-analysis

    Oteng-Ntim, E., Mononen, S., Sawicki, O., Seed, P. T., Bick, D. & Poston, L., Jun 2018, In : BMJ open. 8, 6, 14 p., e018778.

    Research output: Contribution to journalReview article

  28. Unraveling the Underlying Arrhythmia Mechanism in Persistent Atrial Fibrillation: Results From the STARLIGHT Study

    Child, N., Clayton, R. H., Roney, C. H., Laughner, J. I., Shuros, A., Neuzil, P., Petru, J., Jackson, T., Porter, B., Bostock, J., Niederer, S. A., Razavi, R. S., Rinaldi, C. A., Taggart, P., Wright, M. J. & Gill, J., Jun 2018, In : Circulation. Arrhythmia and electrophysiology. 11, 6, p. e005897

    Research output: Contribution to journalArticle

  29. DNA methylation and inflammation marker profiles associated with a history of depression

    Crawford, B., Craig, Z., Mansell, G., White, I., Smith, A., Spaull, S., Imm, J., Hannon, E., Wood, A., Yaghootkar, H., Ji, Y., Mullins, N., Lewis, C. M., Mill, J. & Murphy, T. M., 22 May 2018, In : Human Molecular Genetics. 27, 16, p. 2840-2850 11 p.

    Research output: Contribution to journalArticle

  30. New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

    Fabbri, C., Tansey, K., Perlis, R., Hauser, J., Henigsberg, N., Maier, W., Mors, O., Placentino, A., Rietschel, M., Souery, D., Breen, G., Curtis, C., Sang-Hyuk, L., Newhouse, S., Patel, H., Guipponi, M., Perroud, N., Bondolfi, G., O'Donovan, M., Lewis, G. & 8 others, Biernacka, J., Weinshilboum, R., Farmer, A., Aitchison, K., Craig, I., McGuffin, P., Uher, R. & Lewis, C., 22 May 2018, In : The pharmacogenomics journal. 18, p. 413-421

    Research output: Contribution to journalArticle

  31. Exome array analysis of adverse reactions to fluoropyrimidine-based therapy for gastrointestinal cancer

    Traylor, M., Walker, J. L., Corrigan, A. A., Hernandez, M. A., Newhouse, S. J., Folarin, A. A., Patel, H., Ross, P. J., Sanderson, J. D., Spicer, J., Prescott, N. J., Mathew, C. G., Marinaki, A. M. & Lewis, C. M., 1 May 2018, In : PLoS ONE. 13, 5, 11 p., e0188911.

    Research output: Contribution to journalArticle

  32. Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

    The Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Wray, N. R., Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., Agerbo, E., Air, T. M., Andlauer, T. M. F., Bacanu, S-A., Bækvad-Hansen, M., Beekman, A. F. T., Bigdeli, T. B., Binder, E. B., Blackwood, D. R. H., Bryois, J., Buttenschøn, H. N., Bybjerg-Grauholm, J. & 32 others, Cai, N., Castelao, E., Christensen, J. H., Clarke, T., Coleman, J. I. R., Colodro-Conde, L., Couvy-Duchesne, B., Craddock, N., Crawford, G. E., Crowley, C. A., Dashti, H. S., Davies, G., Deary, I. J., Degenhardt, F., Derks, E. M., Direk, N., Eley, T. C., Gaspar, H. A., Hansen, T. F., Li, Y., Mcguffin, P., Mill, J., Mullins, N., Purcell, S. M., Riley, B. P., Smith, D. J., Tansey, K. E., Traylor, M., Uher, R., Lewis, C. M., Breen, G. & O'Reilly, P. F., 1 May 2018, In : Nature Genetics. 50, 5, p. 668-681

    Research output: Contribution to journalArticle

  33. Evaluation of a novel vital sign device to reduce maternal mortality and morbidity in low-resource settings: a mixed method feasibility study for the CRADLE-3 trial

    Vousden, N., Lawley, E., Nathan, H. L., Seed, P. T., Brown, A., Muchengwa, T., Charantimath, U., Bellad, M., Gidiri, M. F., Goudar, S., Chappell, L. C., Sandall, J., Shennan, A. H. & CRADLE Trial Collaborative Group, 27 Apr 2018, In : BMC Pregnancy and Childbirth. 18, 1, 115.

    Research output: Contribution to journalArticle

  34. Addendum: Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

    Howard, D. M., Adams, M. J., Shirali, M., Clarke, T. K., Marioni, R. E., Davies, G., Coleman, J. R. I., Alloza, C., Shen, X., Barbu, M. C., Wigmore, E. M., Gibson, J., Hagenaars, S. P., Lewis, C. M., Ward, J., Smith, D. J., Sullivan, P. F., Haley, C. S., Breen, G., Deary, I. J. & 1 others, McIntosh, A. M., 16 Apr 2018, In : Nature Communications. 9, 1, p. 1-3 1 p.

    Research output: Contribution to journalArticle

  35. Beat-to-beat variability of ventricular action potential duration oscillates at low frequency during sympathetic provocation in humans

    Porter, B., van Duijvenboden, S., Bishop, M. J., Orini, M., Claridge, S., Gould, J., Sieniewicz, B. J., Sidhu, B., Razavi, R., Rinaldi, C. A., Gill, J. S. & Taggart, P., 4 Apr 2018, In : Frontiers in Physiology. 9, APR, 147.

    Research output: Contribution to journalArticle

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