King's College London

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Research Outputs

  1. 2019
  2. Cardiac monocytes and macrophages after myocardial infarction

    Peet, C., Ivetic, A., Bromage, D. I. & Shah, A. M., 16 Dec 2019, In : Cardiovascular Research. cvz336.

    Research output: Contribution to journalArticle

  3. Cognition at age 70: Life course predictors and associations with brain pathologies

    Lu, K., Nicholas, J. M., Collins, J. D., James, S-N., Parker, T. D., Lane, C. A., Keshavan, A., Keuss, S. E., Buchanan, S. M., Murray-Smith, H., Cash, D. M., Sudre, C. H., Malone, I. B., Coath, W., Wong, A., Henley, S. M. D., Crutch, S. J., Fox, N. C., Richards, M. & Schott, J. M., 3 Dec 2019, In : Neurology. 93, 23, p. e2144-e2156

    Research output: Contribution to journalArticle

  4. Semantic computational analysis of anticoagulation use in atrial fibrillation from real world data

    Bean, D., Teo, J., Wu, H., Oliveira, R., Patel, R., Bendayan, R., Shah, A. M., Dobson, R. J. B. & Scott, P. A., 25 Nov 2019, In : PLOS One. 14, 11, e0225625.

    Research output: Contribution to journalArticle

  5. Association of troponin level and age with mortality in 250 000 patients: cohort study across five UK acute care centres

    Kaura, A., Panoulas, V., Glampson, B., Davies, J., Mulla, A., Woods, K., Omigie, J., Shah, A. D., Channon, K. M., Weber, J. N., Thursz, M. R., Elliott, P., Hemingway, H., Williams, B., Asselbergs, F., O'Sullivan, M., Kharbanda, R., Lord, G. M., Melikian, N., Patel, R. S. & 4 others, Perera, D., Shah, A. M., Francis, D. P. & Mayet, J., 20 Nov 2019, In : BMJ (Clinical research ed.). 367, p. l6055 l6055.

    Research output: Contribution to journalArticle

  6. Prelamin A mediates myocardial inflammation in dilated and HIV-Associated cardiomyopathies

    Brayson, D., Frustaci, A., Verardo, R., Chimenti, C., Russo, M. A., Hayward, R., Ahmad, S. M., Vizcay-barrena, G., Protti, A., Zammit, P. S., Dos Remedios, C. G., Ehler, E., Shah, A. M. & Shanahan, C. M., 14 Nov 2019, In : JCI Insight. 4, 22, e126315.

    Research output: Contribution to journalArticle

  7. Pure tone audiometry and cerebral pathology in healthy older adults

    Parker, T., Cash, D. M., Lane, C., Lu, K., Malone, I. B., Nicholas, J. M., James, S., Keshavan, A., Murray-Smith, H., Wong, A., Buchannan, S., Keuss, S., Sudre, C. H., Thomas, D., Crutch, S., Bamiou, D-E., Warren, J. D., Fox, N. C., Richards, M. & Schott, J. M., 7 Nov 2019, In : Journal of neurology, neurosurgery, and psychiatry.

    Research output: Contribution to journalArticle

  8. Associations Between Vascular Risk Across Adulthood and Brain Pathology in Late Life: Evidence From a British Birth Cohort

    Lane, C. A., Barnes, J., Nicholas, J. M., Sudre, C. H., Cash, D. M., Malone, I. B., Parker, T. D., Keshavan, A., Buchanan, S. M., Keuss, S. E., James, S-N., Lu, K., Murray-Smith, H., Wong, A., Gordon, E., Coath, W., Modat, M., Thomas, D., Richards, M., Fox, N. C. & 1 others, Schott, J. M., 4 Nov 2019, In : JAMA Neurology. p. 1-9 9 p.

    Research output: Contribution to journalArticle

  9. Therapies to limit myocardial injury in animal models of myocarditis: a systematic review and meta-analysis

    Silverblatt, J. A., Ziff, O. J., Dancy, L., Daniel, A., Carter, B. R., Scott, P. A., Sado, D., Shah, A. M. & Bromage, D. I., Nov 2019, In : Basic Research in Cardiology. 114, 6, 48.

    Research output: Contribution to journalArticle

  10. Distinct tau PET patterns in atrophy-defined subtypes of Alzheimer's disease

    Ossenkoppele, R., Lyoo, C. H., Sudre, C. H., van Westen, D., Cho, H., Ryu, Y. H., Choi, J. Y., Smith, R., Strandberg, O., Palmqvist, S., Westman, E., Tsai, R., Kramer, J., Boxer, A. L., Gorno-Tempini, M. L., La Joie, R., Miller, B. L., Rabinovici, G. D. & Hansson, O., 28 Oct 2019, In : Alzheimer's & Dementia.

    Research output: Contribution to journalArticle

  11. Assessing the role of extracellular signal-regulated kinases 1 and 2 in volume overload-induced cardiac remodelling

    Jochmann, S., Elkenani, M., Mohamed, B. A., Buchholz, E., Lbik, D., Binder, L., Lorenz, K., Shah, A. M., Hasenfuß, G., Toischer, K. & Schnelle, M., 1 Oct 2019, In : ESC Heart Failure. 6, 5, p. 1015-1026 12 p.

    Research output: Contribution to journalArticle

  12. Associations between blood pressure across adulthood and late-life brain structure and pathology in the neuroscience substudy of the 1946 British birth cohort (Insight 46): an epidemiological study

    Lane, C. A., Barnes, J., Nicholas, J. M., Sudre, C. H., Cash, D. M., Parker, T. D., Malone, I. B., Lu, K., James, S-N., Keshavan, A., Murray-Smith, H., Wong, A., Buchanan, S. M., Keuss, S. E., Gordon, E., Coath, W., Barnes, A., Dickson, J., Modat, M., Thomas, D. & 5 others, Crutch, S. J., Hardy, R., Richards, M., Fox, N. C. & Schott, J. M., 1 Oct 2019, In : Lancet Neurology. 18, 10, p. 942-952 11 p.

    Research output: Contribution to journalArticle

  13. Cortical cerebral blood flow in ageing: effects of haematocrit, sex, ethnicity and diabetes

    Smith, L. A., Melbourne, A., Owen, D., Cardoso, M. J., Sudre, C. H., Tillin, T., Sokolska, M., Atkinson, D., Chaturvedi, N., Ourselin, S., Hughes, A. D., Barkhof, F. & Jäger, H. R., 1 Oct 2019, In : European Radiology. 29, 10, p. 5549-5558 10 p.

    Research output: Contribution to journalArticle

  14. The quantitative neuroradiology initiative framework: application to dementia

    Goodkin, O., Pemberton, H., Vos, S. B., Prados, F., Sudre, C. H., Moggridge, J., Cardoso, M. J., Ourselin, S., Bisdas, S., White, M., Yousry, T., Thornton, J. & Barkhof, F., Sep 2019, In : British Journal of Radiology. 92, 1101, p. 20190365 20190365.

    Research output: Contribution to journalReview article

  15. Multi-Domain Adaptation in Brain MRI through Paired Consistency and Adversarial Learning

    Orbes-Arteaga, M., Varsavsky, T., Sudre, C. H., Eaton-Rosen, Z., Haddow, L. J., Sørensen, L., Nielsen, M., Pai, A., Ourselin, S., Modat, M., Nachev, P. & Cardoso, M. J., 16 Aug 2019, In : DART 2019. p. 54-62 9 p.

    Research output: Contribution to journalArticle

  16. Associations of brain pathology, cognitive and physical markers with age in cognitively normal individuals aged 60-102 years

    Legdeur, N., Tijms, B. M., Konijnenberg, E., den Braber, A., Ten Kate, M., Sudre, C. H., Tomassen, J., Badissi, M., Yaqub, M., Barkhof, F., van Berckel, B. N., Boomsma, D. I., Scheltens, P., Holstege, H., Maier, A. B. & Visser, P. J., 14 Aug 2019, In : The journals of gerontology. Series A, Biological sciences and medical sciences.

    Research output: Contribution to journalArticle

  17. Single-cell transcriptome analyses reveal novel targets modulating cardiac neovascularization by resident endothelial cells following myocardial infarction

    Li, Z., Solomonidis, E. G., Meloni, M., Taylor, R. S., Duffin, R., Dobie, R., Magalhaes, M. S., Henderson, B. E. P., Louwe, P. A., D'Amico, G., Hodivala-Dilke, K. M., Shah, A. M., Mills, N. L., Simons, B. D., Gray, G. A., Henderson, N. C., Baker, A. H. & Brittan, M., 7 Aug 2019, In : European Heart Journal. 40, 30, p. 2507-2520 14 p.

    Research output: Contribution to journalArticle

  18. The continuous heart failure spectrum: moving beyond an ejection fraction classification

    Triposkiadis, F., Butler, J., Abboud, F. M., Armstrong, P. W., Adamopoulos, S., Atherton, J. J., Backs, J., Bauersachs, J., Burkhoff, D., Bonow, R. O., Chopra, V. K., de Boer, R. A., de Windt, L., Hamdani, N., Hasenfuss, G., Heymans, S., Hulot, J. S., Konstam, M., Lee, R. T., Linke, W. A. & 22 others, Lunde, I. G., Lyon, A. R., Maack, C., Mann, D. L., Mebazaa, A., Mentz, R. J., Nihoyannopoulos, P., Papp, Z., Parissis, J., Pedrazzini, T., Rosano, G., Rouleau, J., Seferovic, P. M., Shah, A. M., Starling, R. C., Tocchetti, C. G., Trochu, J. N., Thum, T., Zannad, F., Brutsaert, D. L., Segers, V. F. & De Keulenaer, G. W., 1 Jul 2019, In : European Heart Journal. 40, 26, p. 2155-2163B 9 p.

    Research output: Contribution to journalReview article

  19. Oxidation of PKGIα mediates an endogenous adaptation to pulmonary hypertension

    Rudyk, O., Rowan, A., Prysyazhna, O., Krasemann, S., Hartmann, K., Zhang, M., Shah, A. M., Ruppert, C., Weiss, A., Schermuly, R. T., Ida, T., Akaike, T., Zhao, L. & Eaton, P., 25 Jun 2019, In : PNAS. 116, 26, p. 13016-13025 10 p.

    Research output: Contribution to journalArticle

  20. Metabolically activated adipose tissue macrophages link obesity to triple-negative breast cancer

    Tiwari, P., Blank, A., Cui, C., Schoenfelt, K. Q., Zhou, G., Xu, Y., Khramtsova, G., Olopade, F., Shah, A. M., Khan, S. A., Rosner, M. R. & Becker, L., 3 Jun 2019, In : The Journal of experimental medicine. 216, 6, p. 1345-1358 14 p.

    Research output: Contribution to journalArticle

  21. Applying causal models to explore the mechanism of action of simvastatin in progressive multiple sclerosis

    Eshaghi, A., Kievit, R. A., Prados, F., Sudre, C. H., Nicholas, J., Cardoso, M. J., Chan, D., Nicholas, R., Ourselin, S., Greenwood, J., Thompson, A. J., Alexander, D. C., Barkhof, F., Chataway, J. & Ciccarelli, O., 28 May 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 22, p. 11020-11027 8 p.

    Research output: Contribution to journalArticle

  22. Effect of Iron Isomaltoside on Skeletal Muscle Energetics in Patients with Chronic Heart Failure and Iron Deficiency: FERRIC-HF II Randomized Mechanistic Trial

    Charles-Edwards, G., Amaral, N., Sleigh, A., Ayis, S., Catibog, N., McDonagh, T., Monaghan, M., Amin-Youseff, G., Kemp, G. J., Shah, A. M. & Okonko, D. O., 21 May 2019, In : Circulation. 139, 21, p. 2386-2398 13 p.

    Research output: Contribution to journalArticle

  23. Cardioprotective Effect of the Mitochondrial Unfolded Protein Response During Chronic Pressure Overload

    Smyrnias, I., Gray, S. P., Okonko, D. O., Sawyer, G., Zoccarato, A., Catibog, N., López, B., González, A., Ravassa, S., Díez, J. & Shah, A. M., 16 Apr 2019, In : Journal of the American College of Cardiology. 73, 14, p. 1795 - 1806 12 p.

    Research output: Contribution to journalArticle

  24. Magnetisation transfer ratio abnormalities in primary and secondary progressive multiple sclerosis

    Brown, J. W. L., Chowdhury, A., Kanber, B., Prados Carrasco, F., Eshaghi, A., Sudre, C. H., Pardini, M., Samson, R. S., van de Pavert, S. H., Wheeler-Kingshott, C. G. & Chard, D. T., 8 Apr 2019, In : Multiple sclerosis (Houndmills, Basingstoke, England).

    Research output: Contribution to journalArticle

  25. Standardized Assessment of Automatic Segmentation of White Matter Hyperintensities and Results of the WMH Segmentation Challenge

    Kuijf, H. J., Biesbroek, J. M., De Bresser, J., Heinen, R., Andermatt, S., Bento, M., Berseth, M., Belyaev, M., Cardoso, M. J., Casamitjana, A., Collins, D. L., Dadar, M., Georgiou, A., Ghafoorian, M., Jin, D., Khademi, A., Knight, J., Li, H., Llado, X., Luna, M. & 24 others, Mahmood, Q., Mckinley, R., Mehrtash, A., Ourselin, S., Park, B., Park, H., Park, S. H., Pezold, S., Puybareau, E., Rittner, L., Sudre, C. H., Valverde, S., Vilaplana, V., Wiest, R., Xu, Y., Xu, Z., Zeng, G., Zhang, J., Zheng, G., Chen, C., Van Der Flier, W., Barkhof, F., Viergever, M. A. & Biessels, G. J., 19 Mar 2019, In : IEEE transactions on medical imaging. 38, 11, p. 2556-2568 13 p.

    Research output: Contribution to journalArticle

  26. Paracrine Mechanisms of Redox Signalling for Postmitotic Cell and Tissue Regeneration

    Hervera, A., Santos, C. X., De Virgiliis, F., Shah, A. M. & Di Giovanni, S., 19 Feb 2019, In : Trends in cell biology. 29, 6, p. 514-530 17 p.

    Research output: Contribution to journalReview article

  27. A machine learning approach for the prediction of pulmonary hypertension

    Leha, A., Hellenkamp, K., Unsöld, B., Mushemi-Blake, S., Shah, A. M., Hasenfuß, G. & Seidler, T., 1 Jan 2019, In : PLoS ONE. 14, 10, e0224453.

    Research output: Contribution to journalArticle

  28. Comorbid amyloid-β pathology affects clinical and imaging features in VCD

    Leijenaar, J. F., Groot, C., Sudre, C. H., Bergeron, D., Leeuwis, A. E., Cardoso, M. J., Carrasco, F. P., Laforce, R., Barkhof, F., van der Flier, W. M., Scheltens, P., Prins, N. D. & Ossenkoppele, R., 1 Jan 2019, In : Alzheimer's and Dementia.

    Research output: Contribution to journalArticle

  29. Imaging biomarkers in alzheimer’s disease

    Sudre, C. H., Jorge Cardoso, M., Modat, M. & Ourselin, S., 1 Jan 2019, Handbook of Medical Image Computing and Computer Assisted Intervention. Elsevier, p. 343-378 36 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

  30. Let’s agree to disagree: Learning highly debatable multirater labelling

    Sudre, C. H., Anson, B. G., Ingala, S., Lane, C. D., Jimenez, D., Haider, L., Varsavsky, T., Tanno, R., Smith, L., Ourselin, S., Jäger, R. H. & Cardoso, M. J., 1 Jan 2019, Medical Image Computing and Computer Assisted Intervention – MICCAI 2019 - 22nd International Conference, Proceedings. Shen, D., Yap, P-T., Liu, T., Peters, T. M., Khan, A., Staib, L. H., Essert, C. & Zhou, S. (eds.). SPRINGER, p. 665-673 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11767 LNCS).

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  31. Periventricular magnetisation transfer ratio abnormalities in multiple sclerosis improve after alemtuzumab

    Brown, J. W. L., Prados Carrasco, F., Eshaghi, A., Sudre, C. H., Button, T., Pardini, M., Samson, R. S., Ourselin, S., Wheeler-Kingshott, C. AM. G., Jones, J. L., Coles, A. J. & Chard, D. T., 1 Jan 2019, In : Multiple Sclerosis Journal.

    Research output: Contribution to journalArticle

  32. Physics-informed brain MRI segmentation

    Borges, P., Sudre, C., Varsavsky, T., Thomas, D., Drobnjak, I., Ourselin, S. & Cardoso, M. J., 1 Jan 2019, Simulation and Synthesis in Medical Imaging - 4th International Workshop, SASHIMI 2019, Held in Conjunction with MICCAI 2019, Proceedings. Burgos, N., Gooya, A. & Svoboda, D. (eds.). SPRINGER, p. 100-109 10 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11827 LNCS).

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  33. Prion disease diagnosis using subject-specific imaging biomarkers within a multi-kernel Gaussian process

    Canas, L. S., Sudre, C. H., De Vita, E., Nihat, A., Mok, T. H., Slattery, C. F., Paterson, R. W., Foulkes, A. J. M., Hyare, H., Cardoso, M. J., Thornton, J., Schott, J. M., Barkhof, F., Collinge, J., Ourselin, S., Mead, S. & Modat, M., 1 Jan 2019, In : NeuroImage: Clinical. 24, 102051.

    Research output: Contribution to journalArticle

  34. Single-subject structural cortical networks in clinically isolated syndrome

    for the MAGNIMS Study Group, 1 Jan 2019, In : Multiple Sclerosis Journal.

    Research output: Contribution to journalArticle

  35. Tolerizing CTL by sustained hepatic PD-L1 expression provides a new therapy approach in mouse sepsis

    Von Knethen, A., Schäfer, A., Kuchler, L., Knape, T., Christen, U., Hintermann, E., Fißlthaler, B., Schröder, K., Brandes, R. P., Genz, B., Abshagen, K., Pützer, B. M., Sha, L. K., Weigert, A., Syed, S. N., Schulz, M., Shah, A. M., Ernst, A., Putyrski, M., Finkelmeier, F. & 7 others, Pesic, M., Greten, F., Hogardt, M., Kempf, V. A. J., Gunne, S., Parnham, M. J. & Brüne, B., 1 Jan 2019, In : Theranostics. 9, 7, p. 2003-2016 14 p.

    Research output: Contribution to journalArticle

  36. White matter hyperintensities in progranulin-associated frontotemporal dementia: A longitudinal GENFI study

    Sudre, C. H., Bocchetta, M., Heller, C., Convery, R., Neason, M., Moore, K. M., Cash, D. M., Thomas, D. L., Woollacott, I. O. C., Foiani, M., Heslegrave, A., Shafei, R., Greaves, C., van Swieten, J., Moreno, F., Sanchez-Valle, R., Borroni, B., Laforce, R., Masellis, M., Tartaglia, M. C. & 21 others, Graff, C., Galimberti, D., Rowe, J. B., Finger, E., Synofzik, M., Vandenberghe, R., de Mendonça, A., Tagliavini, F., Santana, I., Ducharme, S., Butler, C., Gerhard, A., Levin, J., Danek, A., Frisoni, G. B., Sorbi, S., Otto, M., Zetterberg, H., Ourselin, S., Cardoso, M. J. & Rohrer, J. D., 1 Jan 2019, In : NeuroImage: Clinical. 24, 102077.

    Research output: Contribution to journalArticle

  37. Hippocampal subfield volumes and pre-clinical Alzheimer's disease in 408 cognitively normal adults born in 1946

    Parker, T. D., Cash, D. M., Lane, C. A. S., Lu, K., Malone, I. B., Nicholas, J. M., James, S-N., Keshavan, A., Murray-Smith, H., Wong, A., Buchanan, S. M., Keuss, S. E., Sudre, C. H., Modat, M., Thomas, D. L., Crutch, S. J., Richards, M., Fox, N. C. & Schott, J. M., 2019, In : PLoS ONE. 14, 10, p. e0224030 e0224030.

    Research output: Contribution to journalArticle

  38. Magnetic Resonance Perfusion or Fractional Flow Reserve in Coronary Disease

    Nagel, E., Greenwood, J. P., McCann, G. P., Bettencourt, N., Shah, A. M., Hussain, S. T., Perera, D., Plein, S., Bucciarelli-Ducci, C., Paul, M., Westwood, M. A., Marber, M. & Investigators, MR-INFORM., 2019, In : New England Journal of Medicine. 380, 25, p. 2418-2428 11 p.

    Research output: Contribution to journalArticle

  39. Spatial patterns of white matter hyperintensities associated with Alzheimer's disease risk factors in a cognitively healthy middle-aged cohort

    Salvadó, G., Brugulat-Serrat, A., Sudre, C. H., Grau-Rivera, O., Suárez-Calvet, M., Falcon, C., Fauria, K., Cardoso, M. J., Barkhof, F., Molinuevo, J. L. & Gispert, J. D., 2019, In : Alzheimer's Research and Therapy. 11, 1, p. 1-14 12.

    Research output: Contribution to journalArticle

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