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Research Outputs

  1. 2019
  2. Intervention planning and modification of the BUMP intervention: A digital intervention for the early detection of raised blood pressure in pregnancy

    Band, R., Hinton, L., Tucker, K. L., Chappell, L. C., Crawford, C., Franssen, M., Greenfield, S., Hodgkinson, J., McCourt, C., McManus, R. J., Sandall, J., Santos, M. D., Velardo, C. & Yardley, L., 20 Dec 2019, In : Pilot and Feasibility Studies. 5, 1, 153.

    Research output: Contribution to journalArticle

  3. Altered structural brain asymmetry in autism spectrum disorder in a study of 54 datasets

    Postema, M. C., van Rooij, D., Anagnostou, E., Arango, C., Auzias, G., Behrmann, M., Filho, G. B., Calderoni, S., Calvo, R., Daly, E., Deruelle, C., Di Martino, A., Dinstein, I., Duran, F. L. S., Durston, S., Ecker, C., Ehrlich, S., Fair, D., Fedor, J., Feng, X. & 38 others, Fitzgerald, J., Floris, D. L., Freitag, C. M., Gallagher, L., Glahn, D. C., Gori, I., Haar, S., Hoekstra, L., Jahanshad, N., Jalbrzikowski, M., Janssen, J., King, J. A., Kong, X. Z., Lazaro, L., Lerch, J. P., Luna, B., Martinho, M. M., McGrath, J., Medland, S. E., Muratori, F., Murphy, C. M., Murphy, D. G. M., O'Hearn, K., Oranje, B., Parellada, M., Puig, O., Retico, A., Rosa, P., Rubia, K., Shook, D., Taylor, M. J., Tosetti, M., Wallace, G. L., Zhou, F., Thompson, P. M., Fisher, S. E., Buitelaar, J. K. & Francks, C., 1 Dec 2019, In : Nature Communications. 10, 1, 4958.

    Research output: Contribution to journalArticle

  4. Enzymatic quantification of total serum bile acids as a monitoring strategy for women with intrahepatic cholestasis of pregnancy receiving ursodeoxycholic acid treatment: a cohort study

    Borges Manna, L., Ovadia, C., Lövgren-Sandblom, A., Chambers, J., Begum, S., Seed, P., Walker, I., Chappell, L. C., Marschall, H-U. & Williamson, C., 1 Dec 2019, In : BJOG. 126, 13, p. 1633-1640 8 p.

    Research output: Contribution to journalArticle

  5. Transplacental metoprolol for fetal supraventricular tachycardia

    Vigneswaran, T. V., Rosenthal, E., Bakalis, S., Nelson-Piercy, C., Chappell, L. & Simpson, J. M., 19 Nov 2019, In : Ultrasound in Obstetrics and Gynecology.

    Research output: Contribution to journalArticle

  6. Pregnancy-related Acute Kidney Injury in pre-eclampsia: risk factors and renal outcomes

    Conti-Ramsden, F. I., Nathan, H. L., De Greeff, A., Hall, D. R., Seed, P. T., Chappell, L. C., Shennan, A. H. & Bramham, K., Nov 2019, In : Hypertension. 74, 5, p. 1144–1151 8 p.

    Research output: Contribution to journalArticle

  7. Clinical practice guideline on pregnancy and renal disease

    Wiles, K., Chappell, L., Clark, K., Elman, L., Hall, M., Lightstone, L., Mohamed, G., Mukherjee, D., Nelson-Piercy, C., Webster, P., Whybrow, R. & Bramham, K., 31 Oct 2019, In : BMC Nephrology. 20, 1, 401.

    Research output: Contribution to journalReview article

  8. Father-infant interactions and infant regional brain volumes: a cross-sectional MRI study

    Sethna, V., Pote, I., Wang, S., Gudbrandsen, C. M., Lee, C., Perry, E. L., P H Adams, K., Watson, C., Kangas, J., Murphy, D. G., Daly, E., Stoencheva, V. V., Kuklisova-Murgasova, M., Williams, S. C. R., Craig, M. C. & McAlonan, G. M., 16 Oct 2019, In : Developmental Cognitive Neuroscience.

    Research output: Contribution to journalArticle

  9. A randomised controlled trial of blood pressure self-monitoring in the management of hypertensive pregnancy. OPTIMUM-BP: A feasibility trial

    Pealing, L. M., Tucker, K. L., Mackillop, L. H., Crawford, C., Wilson, H., Nickless, A., Temple, E., Chappell, L. C. & McManus, R. J., 1 Oct 2019, In : Pregnancy Hypertension. 18, p. 141-149 9 p.

    Research output: Contribution to journalArticle

  10. Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial

    PHOENIX Study Group, Chappell, L. C., Brocklehurst, P., Green, M. E., Hunter, R., Hardy, P., Juszczak, E., Linsell, L., Chiocchia, V., Greenland, M., Placzek, A., Townend, J., Sandall, J. & Shennan, A., 28 Sep 2019, In : The Lancet. 394, 10204, p. 1181-1190 10 p.

    Research output: Contribution to journalArticle

  11. Preeclampsia and Cardiovascular Disease in a Large UK Pregnancy Cohort of Linked Electronic Health Records: A CALIBER Study

    Leon, L. J., McCarthy, F. P., Direk, K., Gonzalez-Izquierdo, A., Prieto-Merino, D., Casas, J. P. & Chappell, L., 24 Sep 2019, In : Circulation. 140, 13, p. 1050-1060 11 p.

    Research output: Contribution to journalArticle

  12. Diagnosis and management of hypertension in pregnancy: Summary of updated NICE guidance

    Webster, K., Fishburn, S., Maresh, M., Findlay, S. C. & Chappell, L. C., 9 Sep 2019, In : The BMJ. 366, el5119.

    Research output: Contribution to journalArticle

  13. Ursodeoxycholic acid versus placebo in women with intrahepatic cholestasis of pregnancy (PITCHES): a randomised controlled trial

    PITCHES study group, Chappell, L. C., Bell, J. L., Smith, A., Linsell, L., Juszczak, E., Dixon, P. H., Chambers, J., Hunter, R., Dorling, J., Williamson, C. & Thornton, J. G., 7 Sep 2019, In : The Lancet. 394, 10201, p. 849-860 12 p.

    Research output: Contribution to journalArticle

  14. From pattern classification to stratification: towards conceptualizing the heterogeneity of Autism Spectrum Disorder

    Wolfers, T., Floris, D. L., Dinga, R., van Rooij, D., Isakoglou, C., Kia, S. M., Zabihi, M., Llera, A., Chowdanayaka, R., Kumar, V. J., Peng, H., Laidi, C., Batalle, D., Dimitrova, R., Charman, T., Loth, E., Lai, M-C., Jones, E., Baumeister, S., Moessnang, C. & 8 others, Banaschewski, T., Ecker, C., Dumas, G., O'Muircheartaigh, J., Murphy, D., Buitelaar, J. K., Marquand, A. F. & Beckmann, C. F., Sep 2019, In : Neuroscience and biobehavioral reviews. 104, p. 240-254 15 p.

    Research output: Contribution to journalReview article

  15. Uncertainties in Screening and Prevention of Group B Streptococcus Disease

    Le Doare, K., Heath, P. T., Plumb, J., Owen, N. A., Brocklehurst, P. & Chappell, L. C., 1 Aug 2019, In : Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 69, 4, p. 720-725 6 p.

    Research output: Contribution to journalArticle

  16. Prediction of pre-eclampsia: review of reviews

    on behalf of the IPPIC Network, 1 Jul 2019, In : Ultrasound in Obstetrics and Gynecology. 54, 1, p. 16-27 12 p.

    Research output: Contribution to journalReview article

  17. Quantifying adherence to antihypertensive medication for chronic hypertension during pregnancy

    Webster, L. M., Reed, K., Myers, J. E., Burns, A., Gupta, P., Patel, P., Wiesender, C., Seed, P. T., Nelson-Piercy, C. & Chappell, L. C., 1 Jul 2019, In : Pregnancy Hypertension. 17, p. 12-14 3 p.

    Research output: Contribution to journalArticle

  18. Renal biopsy findings during and after pregnancy

    Conti-Ramsden, F., Bass, P., Chappell, L. C. & Branham, K., 15 Jun 2019, In : Obstetric Medicine.

    Research output: Contribution to journalArticle

  19. Diagnostic Indicators of Superimposed Preeclampsia in Women With CKD

    Wiles, K., Bramham, K., Seed, P. T., Kurlak, L. O., Mistry, H. D., Nelson-piercy, C., Lightstone, L. & Chappell, L. C., 1 Jun 2019, In : Kidney International Reports. 4, 6, p. 842-853 12 p.

    Research output: Contribution to journalArticle

  20. Caring for women with chronic hypertension

    Lovell, H., Wilson, H. M., Whybrow, R., Harding, K. & Chappell, L. C., Jun 2019, In : British Journal of Midwifery. 27, 6, p. 343-351 9 p.

    Research output: Contribution to journalArticle

  21. InSpect: INtegrated SPECTral Component Estimation and Mapping for Multi-contrast Microstructural MRI

    Slator, P. J., Hutter, J., Marinescu, R. V., Palombo, M., Young, A. L., Jackson, L. H., Ho, A., Chappell, L. C., Rutherford, M., Hajnal, J. V. & Alexander, D. C., 22 May 2019, Information Processing in Medical Imaging - 26th International Conference, IPMI 2019, Proceedings. Bao, S., Gee, J. C., Yushkevich, P. A. & Chung, A. C. S. (eds.). p. 755-766 12 p. Chapter 59. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11492 LNCS).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

  22. Placental growth factor testing to assess women with suspected pre-eclampsia: a multicentre, pragmatic, stepped-wedge cluster-randomised controlled trial

    Duhig, K. E., Myers, J., Seed, P. T., Sparkes, J., Lowe, J., Hunter, R. M., Shennan, A. H., Chappell, L. C., Bahl, R., Bambridge, G., Barnfield, S., Ficquet, J., Gill, C., Girling, J., Harding, K., Khalil, A., Sharp, A., Simpson, N. & Tuffnell, D., 4 May 2019, In : The Lancet. 393, 10183, p. 1807-1818 12 p.

    Research output: Contribution to journalArticle

  23. Exploring the effect of implementation and context on a stepped-wedge randomised controlled trial of a vital sign triage device in routine maternity care in low-resource settings

    Vousden, N., Lawley, E., Seed, P. T., Gidiri, M. F., Charantimath, U., Makonyola, G., Brown, A., Yadeta, L., Best, R., Chinkoyo, S., Vwalika, B., Nakimuli, A., Ditai, J., Greene, G., Chappell, L. C., Sandall, J., Shennan, A. H., Bukani, D., Toussaint, P., Vixama, A. & 30 others, Hill, C., Nakirijja, E., Birungi, D., Kalyowa, N., Namakuli, D., Byamugisha, J., Odeke, N. M., Wandabwa, J., Momodou, F., Sesay, M., Sandi, P., Conteh, J., Kamara, J., Clarke, M., Miti, J., Chima, M., Kopeka, M., Jere, C., Musonda, T., Mambo, V., Guchale, Y., Surur, F., Mungarwadi, G. M., Mastiholi, S. S., Karadiguddi, C. C., Hezelgrave, N., Duhig, K. E., Kachinjika, M., Bellad, M. & Makwakwa, J., 18 Apr 2019, In : Implementation Science. 14, 1, 38.

    Research output: Contribution to journalArticle

  24. Investigating the Factors Underlying Adaptive Functioning in Autism in the EU-AIMS Longitudinal European Autism Project

    Tillmann, J., San Jose Caceres, A., Chatham, C. H., Crawley, D., Holt, R., Oakley, B., Banaschewski, T., Baron-Cohen, S., Bölte, S., Buitelaar, J. K., Durston, S., Ham, L., Loth, E., Simonoff, E., Spooren, W., Murphy, D. G. & Charman, T., 5 Apr 2019, In : Autism research. 12, 4, p. 645-657 13 p.

    Research output: Contribution to journalArticle

  25. Incidence of eclampsia and related complications across 10 low- and middle-resource geographical regions: Secondary analysis of a cluster randomised controlled trial

    CRADLE Trial Collaborative Group, 29 Mar 2019, In : PLoS Medicine. 16, 3, 15 p., e1002775.

    Research output: Contribution to journalArticle

  26. Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses

    Ovadia, C., Seed, P. T., Sklavounos, A., Geenes, V., Di Illio, C., Chambers, J., Kohari, K., Bacq, Y., Bozkurt, N., Brun-furrer, R., Bull, L., Estiú, M. C., Grymowicz, M., Gunaydin, B., Hague, W. M., Haslinger, C., Hu, Y., Kawakita, T., Kebapcilar, A. G., Kebapcilar, L. & 20 others, Kondrackienė, J., Koster, M. P. H., Kowalska-kańka, A., Kupčinskas, L., Lee, R. H., Locatelli, A., Macias, R. I. R., Marschall, H., Oudijk, M. A., Raz, Y., Rimon, E., Shan, D., Shao, Y., Tribe, R., Tripodi, V., Yayla Abide, C., Yenidede, I., Thornton, J. G., Chappell, L. C. & Williamson, C., 2 Mar 2019, In : The Lancet. 393, 10174, p. 899-909 11 p.

    Research output: Contribution to journalArticle

  27. Altered Connectivity Between Cerebellum, Visual, and Sensory-Motor Networks in Autism Spectrum Disorder: Results from the EU-AIMS Longitudinal European Autism Project

    Oldehinkel, M., Mennes, M., Marquand, A., Charman, T., Tillmann, J., Ecker, C., Dell’acqua, F., Brandeis, D., Banaschewski, T., Baumeister, S., Moessnang, C., Holt, R., Baron-cohen, S., Bölte, S., Durston, S., Kundu, P., Lombardo, M. V., Spooren, W., Loth, E., Murphy, D. G. M. & 31 others, Beckmann, C. F., Buitelaar, J. K., EU-AIMS LEAP group, Ahmad, J., Ambrosino, S., Auyeung, B., Banaschewski, T., Baron-cohen, S., Baumeister, S., Beckmann, C. F., Bölte, S., Bourgeron, T., Bours, C., Brammer, M., Brandeis, D., Brogna, C., Charman, T., Crawley, D., Ecker, C., Faulkner, J., Hayward, H., Loth, E., Lythgoe, D. J., Marquand, A., Murphy, D. G. M., Oakley, B., Ruggeri, B., San José Cáceres, A., Simonoff, E., Tillmann, J. & Williams, S. C. R., Mar 2019, In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 3, p. 260-270

    Research output: Contribution to journalArticle

  28. Effect of a novel vital sign device on maternal mortality and morbidity in low-resource settings: a pragmatic, stepped-wedge, cluster-randomised controlled trial

    CRADLE Trial Collaborative Group, Vousden, N., Lawley, E., Nathan, H. L., Seed, P. T., Gidiri, M. F., Goudar, S., Sandall, J., Chappell, L. C., Shennan, A. H., Kachinjika, M., Bukani, D., Makwakwa, J., Makonyola, G., Brown, A., Toussaint, P., Vixama, A., Greene, G., Hill, C., Nakiriija, E. & 31 others, Birungi, D., Kalyowa, N., Namakula, D., Byamugisha, J., Nakimuli, A., Mackayi Odeke, N., Ditai, J., Wandabwa, J., Momodou, F., Sesay, M., Sandi, P., Conteh, J., Kamara, J., Clarke, M., Best, R., Miti, J., Kopeka, M., Vwalika, B., Chima, M., Musonda, T., Jere, C., Chinkoyo, S., Mambo, V., Guchale, Y., Yadeta, L., Surur, F., Mungarwadi, G. M., Mastiholi, S. S., Karadiguddi, C. C., Hezelgrave, N. & Duhig, K. E., Mar 2019, In : The Lancet. Global health. 7, 3, p. e347-e356

    Research output: Contribution to journalArticle

  29. Serum creatinine in pregnancy: a systematic review

    Wiles, K., Bramham, K., Seed, P. T., Nelson-Piercy, C., Lightstone, L. & Chappell, L. C., Mar 2019, In : Kidney International Reports. 4, 3, p. 408-419 12 p.

    Research output: Contribution to journalArticle

  30. Patients with autism spectrum disorders display reproducible functional connectivity alterations

    Holiga, Š., Hipp, J. F., Chatham, C. H., Garces, P., Spooren, W., D’Ardhuy, X. L., Bertolino, A., Bouquet, C., Buitelaar, J. K., Bours, C., Rausch, A., Oldehinkel, M., Bouvard, M., Amestoy, A., Caralp, M., Gueguen, S., Moal, M. L. L., Houenou, J., Beckmann, C. F., Loth, E. & 15 others, Murphy, D., Charman, T., Tillmann, J., Laidi, C., Delorme, R., Beggiato, A., Gaman, A., Scheid, I., Leboyer, M., d’Albis, M. A., Sevigny, J., Czech, C., Bolognani, F., Honey, G. D. & Dukart, J., 27 Feb 2019, In : Science Translational Medicine. 11, 481, eaat9223.

    Research output: Contribution to journalArticle

  31. Planned delivery or expectant management for late preterm pre-eclampsia: Study protocol for a randomised controlled trial (PHOENIX trial)

    Chappell, L. C., Green, M., Marlow, N., Sandall, J., Hunter, R., Robson, S., Bowler, U., Chiocchia, V., Hardy, P., Juszczak, E., Linsell, L., Placzek, A., Brocklehurst, P. & Shennan, A., 28 Jan 2019, In : Trials. 20, 1, p. 85 85.

    Research output: Contribution to journalArticle

  32. Reducing maternal deaths from hypertensive disorders: Learning from confidential inquiries

    Conti-Ramsden, F., Knight, M., Green, M., Shennan, A. H. & Chappell, L. C., 1 Jan 2019, In : BMJ (Online). 364, l230.

    Research output: Contribution to journalArticle

  33. Temporal and external validation of the fullPIERS model for the prediction of adverse maternal outcomes in women with pre-eclampsia

    Ukah, U. V., Payne, B., Karjalainen, H., Kortelainen, E., Seed, P. T., Conti-Ramsden, F. I., Cao, V., Laivuori, H., Hutcheon, J., Chappell, L., Ansermino, J. M., Vatish, M., Redman, C., Lee, T., Li, L., Magee, L. A. & von Dadelszen, P., Jan 2019, In : Pregnancy Hypertension. 15, p. 42-50 9 p.

    Research output: Contribution to journalArticle

  34. Altered white matter microstructure in 22q11.2 deletion syndrome: a multisite diffusion tensor imaging study

    Villalon-Reina, J. E., Martínez, K., Qu, X., Ching, C. R. K., Nir, T., Kothapalli, D., Corbin, C., Sun, D., Lin, A., Forsyth, J. K., Kushan, L., Vajdi, A., Jalbrzikowski, M., Hansen, L., Jonas, R. K., Van Amelsvoort, T., Bakker, G., Kates, W. R., Antshel, K. M., Fremont, W. & 33 others, Campbell, L. E., McCabe, K. L., Gudbrandsen, C. M., Daly, E. M., Gudbrandsen, C. M., Murphy, C., Murphy, D. G., Craig, M., Emanuel, B. S., McDonald-McGinn, D. M., Vorstman, J. A. S., Fiksinski, A., Koops, S., Ruparel, K., Roalf, D. R., Gur, R. E., Schmitt, J. E., Simon, T. J., Goodrich-hunsaker, N. J., Durdle, C. A., Doherty, J., Cunningham, A. C., van den Bree, M., Linden, D. E. J., Owen, M. J., Moss, H., Kelly, S., Donohoe, G., Murphy, K. C., Arango, C., Jahanshad, N., Thompson, P. M. & Bearden, C. E., 2019, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

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