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Research Outputs

  1. 2019
  2. Altered structural brain asymmetry in autism spectrum disorder in a study of 54 datasets

    Postema, M. C., van Rooij, D., Anagnostou, E., Arango, C., Auzias, G., Behrmann, M., Filho, G. B., Calderoni, S., Calvo, R., Daly, E., Deruelle, C., Di Martino, A., Dinstein, I., Duran, F. L. S., Durston, S., Ecker, C., Ehrlich, S., Fair, D., Fedor, J., Feng, X. & 38 others, Fitzgerald, J., Floris, D. L., Freitag, C. M., Gallagher, L., Glahn, D. C., Gori, I., Haar, S., Hoekstra, L., Jahanshad, N., Jalbrzikowski, M., Janssen, J., King, J. A., Kong, X. Z., Lazaro, L., Lerch, J. P., Luna, B., Martinho, M. M., McGrath, J., Medland, S. E., Muratori, F., Murphy, C. M., Murphy, D. G. M., O'Hearn, K., Oranje, B., Parellada, M., Puig, O., Retico, A., Rosa, P., Rubia, K., Shook, D., Taylor, M. J., Tosetti, M., Wallace, G. L., Zhou, F., Thompson, P. M., Fisher, S. E., Buitelaar, J. K. & Francks, C., 1 Dec 2019, In : Nature Communications. 10, 1, 4958.

    Research output: Contribution to journalArticle

  3. Treatment response classes in major depressive disorder identified by model-based clustering and validated by clinical prediction models

    Paul, R., Andlauer, T. F. M., Czamara, D., Hoehn, D., Lucae, S., Pütz, B., Lewis, C. M., Uher, R., Müller-Myhsok, B., Ising, M. & Sämann, P. G., 1 Dec 2019, In : Translational psychiatry. 9, 1, 187.

    Research output: Contribution to journalArticle

  4. Father-infant interactions and infant regional brain volumes: a cross-sectional MRI study

    Sethna, V., Pote, I., Wang, S., Gudbrandsen, C. M., Lee, C., Perry, E. L., P H Adams, K., Watson, C., Kangas, J., Murphy, D. G., Daly, E., Stoencheva, V. V., Kuklisova-Murgasova, M., Williams, S. C. R., Craig, M. C. & McAlonan, G. M., 16 Oct 2019, In : Developmental Cognitive Neuroscience.

    Research output: Contribution to journalArticle

  5. Genetic variation of the endocannabinoids system and risk of first episode psychosis

    Quattrone, D., Vassos, E., Richards, A., Reininghaus, U., Sham, P., O'Donovan, M. C., Lewis, C. M., Murray, R. M. & Di Forti, M., 24 Sep 2019, Genetic variation of the endocannabinoids system and risk of first episode psychosis.

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  6. Gene Variants at Loci Related to Blood Pressure Account for Variation in Response to Antihypertensive Drugs Between Black and White Individuals: Genomic Precision Medicine May Dispense With Ethnicity

    Iniesta, R., Campbell, D., Venturini, C., Faconti, L., Singh, S., Irvin, M. R., Cooper-DeHoff, R. M., Johnson, J. A., Turner, S. T., Arnett, D. K., Weale, M. E., Warren, H., Munroe, P. B., Cruickshank, K., Padmanabhan, S., Lewis, C. & Chowienczyk, P., 1 Sep 2019, In : Hypertension (Dallas, Tex. : 1979). 74, 3, p. 614-622 9 p.

    Research output: Contribution to journalArticle

  7. Prevalence of Advanced Liver Fibrosis in Patients With Severe Psoriasis

    Maybury, C. M., Porter, H. F., Kloczko, E., Duckworth, M., Cotton, A., Thornberry, K., Dew, T., Crook, M., Natas, S., Miquel, R., Lewis, C. M., Wong, T., Smith, C. H. & Barker, J. N., 1 Sep 2019, In : JAMA dermatology. 155, 9, p. 1028-1032 5 p.

    Research output: Contribution to journalArticle

  8. From pattern classification to stratification: towards conceptualizing the heterogeneity of Autism Spectrum Disorder

    Wolfers, T., Floris, D. L., Dinga, R., van Rooij, D., Isakoglou, C., Kia, S. M., Zabihi, M., Llera, A., Chowdanayaka, R., Kumar, V. J., Peng, H., Laidi, C., Batalle, D., Dimitrova, R., Charman, T., Loth, E., Lai, M-C., Jones, E., Baumeister, S., Moessnang, C. & 8 others, Banaschewski, T., Ecker, C., Dumas, G., O'Muircheartaigh, J., Murphy, D., Buitelaar, J. K., Marquand, A. F. & Beckmann, C. F., Sep 2019, In : Neuroscience and biobehavioral reviews. 104, p. 240-254 15 p.

    Research output: Contribution to journalReview article

  9. Genome-wide association study of suicide attempt in psychiatric disorders identifies association with major depression polygenic risk scores

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Mullins, N., Bigdeli, T. B., Børglum, A. D., Coleman, J. R. I., Demontis, D., Mehta, D., Power, R. A., Ripke, S., Stahl, E. A., Starnawska, A., Anjorin, A., Corvin, A., Sanders, A. R., Forstner, A. J., Reif, A., Koller, A. C., Świątkowska, B., Baune, B. T. & 95 others, Müller-Myhsok, B., Penninx, B. W. J. H., Pato, C. N., Zai, C. C., Rujescu, D., Hougaard, D. M., Quested, D., Levinson, D. F., Binder, E. B., Byrne, E. M., Agerbo, E., Streit, F., Mayoral, F., Bellivier, F., Degenhardt, F., Breen, G. D., Morken, G., Turecki, G., Rouleau, G., Grabe, H. J., Volzke, H., Jones, I., Giegling, I., Agartz, I., Melle, I., Lawrence, J., Walters, J. T. R., Strohmaier, J., Shi, J., Hauser, J., Biernacka, J. M., Vincent, J. B., Kelsoe, J., Strauss, J. S., Lissowska, J., Pimm, J., Smoller, J. W., Guzman-Parra, J., Berger, K., Scott, L. J., Jones, L. A., Azevedo, M. H., Trzaskowski, M., Kogevinas, M., Rietschel, M., Boks, M. P., Ising, M., Grigoroiu-Serbanescu, M., Hamshere, M. L., Leboyer, M., Frye, M. A., Alda, M., Nordentoft, M., Boehnke, M., O'Donovan, M. C., Owen, M. J., Pato, M. T., Renteria, M. E., Wray, N. R., Bass, N., Craddock, N., Smeland, O. B., Andreassen, O. A., Mors, O., Gejman, P. V., Sklar, P., McGrath, P. J., Hoffmann, P., McGuffin, P., Lee, P. H., Mortensen, P. B., Kahn, R. S., Ophoff, R. A., Adolfsson, R., Van der Auwera Affiliations, S., Djurovic, S., Kloiber, S., Heilmann-Heimbach, S., Jamain, S., Hamilton, S. P., Mcelroy, S. L., Lucae, S., Cichon, S., Schulze, T. G., Hansen, T., Werge, T., Air, T. M., Nimgaonkar, V., Appadurai, V., Cahn, W., Milaneschi, Y., Fanous, A. H., Kendler, K. S., McQuillin, A. & Lewis, C. M., 1 Aug 2019, In : The American Journal of Psychiatry. 176, 8, p. 651-660 10 p.

    Research output: Contribution to journalArticle

  10. Polygenic risk for circulating reproductive hormone levels and their influence on hippocampal volume and depression susceptibility

    Smeeth, D. M., Dima, D., Jones, L., Jones, I., Craddock, N., Owen, M. J., Rietschel, M., Maier, W., Korszun, A., Rice, J. P., Mors, O., Preisig, M., Uher, R., Lewis, C. M., Thuret, S. & Powell, T. R., Aug 2019, In : Psychoneuroendocrinology. 106, p. 284-292 9 p.

    Research output: Contribution to journalArticle

  11. Genome-wide survey of copy number variants finds MAPT duplications in progressive supranuclear palsy

    NNIPPS and BBBIPPS Study Groups, 1 Jul 2019, In : Movement Disorders. 34, 7, p. 1049-1059 11 p.

    Research output: Contribution to journalArticle

  12. Genome-wide burden of rare short deletions is enriched in Major Depressive Disorder in four cohorts

    Zhang, X., Abdellaoui, A., Rucker, J., de Jong, S., Potash, J. B., Weissman, M. M., Shi, J., Knowles, J. A., Pato, C., Pato, M., Sobell, J., Smit, J. H., Hottenga, J. J., de Geus, E. J. C., Lewis, C. M., Buttenschøn, H. N., Craddock, N., Jones, I., Jones, L., McGuffin, P. & 13 others, Mors, O., Owen, M. J., Preisig, M., Rietschel, M., Rice, J. P., Rivera, M., Uher, R., Gejman, P. V., Sanders, A. R., Boomsma, D., Penninx, B. W. J. H., Breen, G. & Levinson, D. F., 15 Jun 2019, In : Biological psychiatry. 85, 12, p. 1065-1073 9 p.

    Research output: Contribution to journalArticle

  13. Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 11 Jun 2019, In : Nature Communications. 10, 1, p. 1-18 18 p., 2548.

    Research output: Contribution to journalArticle

  14. Using genetics to understand the causal influence of higher BMI on depression

    Tyrrell, J., Mulugeta, A., Wood, A. R., Zhou, A., Beaumont, R. N., Tuke, M. A., Jones, S. E., Ruth, K. S., Yaghootkar, H., Sharp, S., Thompson, W. D., Ji, Y., Harrison, J., Freathy, R. M., Murray, A., Weedon, M. N., Lewis, C., Frayling, T. M. & Hyppönen, E., 1 Jun 2019, In : International Journal of Epidemiology. 48, 3, p. 834-848 15 p.

    Research output: Contribution to journalArticle

  15. ukbTools: An R package to manage and query UK Biobank data

    Hanscombe, K. B., Coleman, J. R. I., Traylor, M. & Lewis, C. M., 31 May 2019, In : PLoS ONE. 14, 5, 6 p., e0214311.

    Research output: Contribution to journalArticle

  16. Evidence of causal effect of major depression on alcohol dependence: Findings from the psychiatric genomics consortium

    Polimanti, R., Peterson, R. E., Ong, J. S., MacGregor, S., Edwards, A. C., Clarke, T. K., Frank, J., Gerring, Z., Gillespie, N. A., Lind, P. A., Maes, H. H., Martin, N. G., Mbarek, H., Medland, S. E., Streit, F., Agrawal, A., Edenberg, H. J., Kendler, K. S., Lewis, C. M., Sullivan, P. F. & 3 others, Wray, N. R., Gelernter, J. & Derks, E. M., 1 May 2019, In : Psychological Medicine. 49, 7, p. 1218-1226 9 p.

    Research output: Contribution to journalArticle

  17. Progressing Polygenic Medicine in Psychiatry Through Electronic Health Records

    Lewis, C. M. & Hagenaars, S. P., 1 May 2019, In : JAMA Psychiatry. 76, 5, p. 470-472 3 p.

    Research output: Contribution to journalEditorial

  18. The contribution of cannabis use to variation in the incidence of psychotic disorder across Europe (EU-GEI): a multicentre case-control study

    EU-GEI WP2 Group, Di Forti, M., Quattrone, D., Freeman, T. P., Tripoli, G., Gayer-Anderson, C., Quigley, H., Rodriguez, V., Jongsma, H. E., Ferraro, L., La Cascia, C., La Barbera, D., Tarricone, I., Berardi, D., Szöke, A., Arango, C., Tortelli, A., Velthorst, E., Bernardo, M., Del-Ben, C. M. & 31 others, Menezes, P. R., Selten, J. P., Jones, P. B., Kirkbride, J. B., Rutten, B. PF., de Haan, L., Sham, P. C., van Os, J., Lewis, C. M., Lynskey, M., Morgan, C., Murray, R. M., Amoretti, S., Arrojo, M., Baudin, G., Beards, S., Bernardo, M., Bobes, J., Bonetto, C., Cabrera, B., Carracedo, A., Charpeaud, T., Costas, J., Cristofalo, D., Cuadrado, P., Díaz-Caneja, C. M., Ferchiou, A., Franke, N., Frijda, F., Hubbard, K. & Stilo, S. A., 1 May 2019, In : The Lancet Psychiatry. 6, 5, p. 427-436 10 p.

    Research output: Contribution to journalArticle

  19. Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder

    eQTLGen Consortium, May 2019, In : Nature Genetics. 51, 5, p. 793-803 11 p.

    Research output: Contribution to journalArticle

  20. Investigating the Factors Underlying Adaptive Functioning in Autism in the EU-AIMS Longitudinal European Autism Project

    Tillmann, J., San Jose Caceres, A., Chatham, C. H., Crawley, D., Holt, R., Oakley, B., Banaschewski, T., Baron-Cohen, S., Bölte, S., Buitelaar, J. K., Durston, S., Ham, L., Loth, E., Simonoff, E., Spooren, W., Murphy, D. G. & Charman, T., 5 Apr 2019, In : Autism research. 12, 4, p. 645-657 13 p.

    Research output: Contribution to journalArticle

  21. Uncovering the Genetic Architecture of Major Depression

    McIntosh, A. M., Sullivan, P. F. & Lewis, C. M., 3 Apr 2019, In : Neuron. 102, 1, p. 91-103 13 p.

    Research output: Contribution to journalReview article

  22. Association of genetic variants in CHEK2 with oesophageal squamous cell carcinoma in the South African Black population

    Chen, W. C., Bye, H., Matejcic, M., Amar, A., Govender, D., Khew, Y. W., Beynon, V., Kerr, R., Singh, E., Prescott, N. J., Lewis, C. M., Babb de Villiers, C., Parker, M. I. & Mathew, C. G., Apr 2019, In : Carcinogenesis. 40, 4, p. 513-520 8 p., bgz026.

    Research output: Contribution to journalArticle

  23. Altered Connectivity Between Cerebellum, Visual, and Sensory-Motor Networks in Autism Spectrum Disorder: Results from the EU-AIMS Longitudinal European Autism Project

    Oldehinkel, M., Mennes, M., Marquand, A., Charman, T., Tillmann, J., Ecker, C., Dell’acqua, F., Brandeis, D., Banaschewski, T., Baumeister, S., Moessnang, C., Holt, R., Baron-cohen, S., Bölte, S., Durston, S., Kundu, P., Lombardo, M. V., Spooren, W., Loth, E., Murphy, D. G. M. & 31 others, Beckmann, C. F., Buitelaar, J. K., EU-AIMS LEAP group, Ahmad, J., Ambrosino, S., Auyeung, B., Banaschewski, T., Baron-cohen, S., Baumeister, S., Beckmann, C. F., Bölte, S., Bourgeron, T., Bours, C., Brammer, M., Brandeis, D., Brogna, C., Charman, T., Crawley, D., Ecker, C., Faulkner, J., Hayward, H., Loth, E., Lythgoe, D. J., Marquand, A., Murphy, D. G. M., Oakley, B., Ruggeri, B., San José Cáceres, A., Simonoff, E., Tillmann, J. & Williams, S. C. R., Mar 2019, In : Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 4, 3, p. 260-270

    Research output: Contribution to journalArticle

  24. Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

    Howard, D. M., Adams, M. J., Clarke, T., Hafferty, J. D., Gibson, J., Shirali, M., Coleman, J. R. I., Hagenaars, S. P., Ward, J., Wigmore, E. M., Alloza, C., Shen, X., Barbu, M. C., Xu, E. Y., Whalley, H. C., Marioni, R. E., Porteous, D. J., Davies, G., Deary, I. J., Hemani, G. & 18 others, Berger, K., Teismann, H., Rawal, R., Arolt, V., Baune, B. T., Dannlowski, U., Domschke, K., Tian, C., Hinds, D. A., Trzaskowski, M., Byrne, E. M., Ripke, S., Smith, D. J., Sullivan, P. F., Wray, N. R., Breen, G., Lewis, C. M. & Mcintosh, A. M., Mar 2019, In : Nature Neuroscience. 22, 3, p. 343-352 10 p.

    Research output: Contribution to journalArticle

  25. Patients with autism spectrum disorders display reproducible functional connectivity alterations

    Holiga, Š., Hipp, J. F., Chatham, C. H., Garces, P., Spooren, W., D’Ardhuy, X. L., Bertolino, A., Bouquet, C., Buitelaar, J. K., Bours, C., Rausch, A., Oldehinkel, M., Bouvard, M., Amestoy, A., Caralp, M., Gueguen, S., Moal, M. L. L., Houenou, J., Beckmann, C. F., Loth, E. & 15 others, Murphy, D., Charman, T., Tillmann, J., Laidi, C., Delorme, R., Beggiato, A., Gaman, A., Scheid, I., Leboyer, M., d’Albis, M. A., Sevigny, J., Czech, C., Bolognani, F., Honey, G. D. & Dukart, J., 27 Feb 2019, In : Science Translational Medicine. 11, 481, eaat9223.

    Research output: Contribution to journalArticle

  26. Identification of common genetic risk variants for autism spectrum disorder

    Autism Spectrum Disorder Working Group of the Psychiatric Genomics Consortium, BUPGEN, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium & 23andMe Research Team, 25 Feb 2019, In : Nature Genetics. 51, 3, p. 431-444 14 p.

    Research output: Contribution to journalArticle

  27. Quantifying between-cohort and between-sex genetic heterogeneity in major depressive disorder

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Feb 2019, In : American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics. 180, 6, p. 439-447 9 p.

    Research output: Contribution to journalArticle

  28. Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP

    Wigmore, E. M., Hafferty, J. D., Hall, L. S., Howard, D. M., Clarke, T-K., Fabbri, C., Lewis, C. M., Uher, R., Navrady, L. B., Adams, M. J., Zeng, Y., Campbell, A., Gibson, J., Thomson, P. A., Hayward, C., Smith, B. H., Hocking, L. J., Padmanabhan, S., Deary, I. J., Porteous, D. J. & 4 others, Mors, O., Mattheisen, M., Nicodemus, K. K. & McIntosh, A. M., 31 Jan 2019, In : The pharmacogenomics journal.

    Research output: Contribution to journalArticle

  29. Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders

    Bipolar Disorder Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Jan 2019, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  30. Cannabis use, depression and self-harm: phenotypic and genetic relationships

    Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, 1 Jan 2019, In : Addiction.

    Research output: Contribution to journalArticle

  31. Genetic associations with radiological damage in rheumatoid arthritis: Meta-analysis of seven genome-wide association studies of 2,775 cases

    Traylor, M., Knevel, R., Cui, J., Taylor, J., Harm-Jan, W., Conaghan, P. G., Cope, A. P., Curtis, C., Emery, P., Newhouse, S., Patel, H., Steer, S., Gregersen, P., Shadick, N. A., Weinblatt, M. E., van der Helm-Van Mil, A., Barrett, J. H., Morgan, A. W., Lewis, C. M. & Scott, I. C., 1 Jan 2019, In : PLoS ONE. 14, 10, e0223246.

    Research output: Contribution to journalArticle

  32. Altered white matter microstructure in 22q11.2 deletion syndrome: a multisite diffusion tensor imaging study

    Villalon-Reina, J. E., Martínez, K., Qu, X., Ching, C. R. K., Nir, T., Kothapalli, D., Corbin, C., Sun, D., Lin, A., Forsyth, J. K., Kushan, L., Vajdi, A., Jalbrzikowski, M., Hansen, L., Jonas, R. K., Van Amelsvoort, T., Bakker, G., Kates, W. R., Antshel, K. M., Fremont, W. & 33 others, Campbell, L. E., McCabe, K. L., Gudbrandsen, C. M., Daly, E. M., Gudbrandsen, C. M., Murphy, C., Murphy, D. G., Craig, M., Emanuel, B. S., McDonald-McGinn, D. M., Vorstman, J. A. S., Fiksinski, A., Koops, S., Ruparel, K., Roalf, D. R., Gur, R. E., Schmitt, J. E., Simon, T. J., Goodrich-hunsaker, N. J., Durdle, C. A., Doherty, J., Cunningham, A. C., van den Bree, M., Linden, D. E. J., Owen, M. J., Moss, H., Kelly, S., Donohoe, G., Murphy, K. C., Arango, C., Jahanshad, N., Thompson, P. M. & Bearden, C. E., 2019, In : Molecular Psychiatry.

    Research output: Contribution to journalArticle

  33. IS THE ERA OF CANDIDATE GENES X CANNABIS USE REALLY DEAD?

    Quattrone, D., Lewis, C., Richards, A., Vassos, E., Gayer-Anderson, C., Ferraro, L., Tripoli, G., Rutten, B., O'Donovan, M., Morgan, C., Van Os, J., Sham, P., Reininghaus, U., Murray, R. & Di Forti, M., 2019, In : European Neuropsychopharmacology. 29, p. 1324-1325

    Research output: Contribution to journalMeeting Abstract

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