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Research Outputs

  1. 2019
  2. Balance of active, passive, and anatomical cardiac properties in doxorubicin-induced heart failure

    Lewalle, A. R. M., Land, S., Merken, J., Raafs, A., Sepulveda, P., Heymans, S., Kleinjans, J. & Niederer, S. A., 17 Dec 2019, In : Biophysical Journal. 117, 12, p. 2337-2348

    Research output: Contribution to journalArticle

  3. Sex-dependent QRS guidelines for Cardiac Resynchronization Therapy using Computer Model Predictions

    Lee, A. W. C., O'Regan, D. P., Gould, J. S., Sidhu, B. S., Sieniewicz, B., Plank, G., Warriner, D. R., Lamata, P., Rinaldi, C. A. & Niederer, S. A., 17 Dec 2019, In : Biophysical Journal. 117, 12, p. 2375-2381

    Research output: Contribution to journalArticle

  4. Cardiac monocytes and macrophages after myocardial infarction

    Peet, C., Ivetic, A., Bromage, D. I. & Shah, A. M., 16 Dec 2019, In : Cardiovascular Research. cvz336.

    Research output: Contribution to journalArticle

  5. The impact of wall thickness and curvature on wall stress in patient-specific electromechanical models of the left atrium

    Augustin, C. M., Fastl, T. E., Neic, A., Bellini, C., Whitaker, J., Rajani, R., O’Neill, M. D., Bishop, M. J., Plank, G. & Niederer, S. A., 4 Dec 2019, In : Biomechanics and Modeling in Mechanobiology.

    Research output: Contribution to journalArticle

  6. Semantic computational analysis of anticoagulation use in atrial fibrillation from real world data

    Bean, D., Teo, J., Wu, H., Oliveira, R., Patel, R., Bendayan, R., Shah, A. M., Dobson, R. J. B. & Scott, P. A., 25 Nov 2019, In : PLOS One. 14, 11, e0225625.

    Research output: Contribution to journalArticle

  7. Association of troponin level and age with mortality in 250 000 patients: cohort study across five UK acute care centres

    Kaura, A., Panoulas, V., Glampson, B., Davies, J., Mulla, A., Woods, K., Omigie, J., Shah, A. D., Channon, K. M., Weber, J. N., Thursz, M. R., Elliott, P., Hemingway, H., Williams, B., Asselbergs, F., O'Sullivan, M., Kharbanda, R., Lord, G. M., Melikian, N., Patel, R. S. & 4 others, Perera, D., Shah, A. M., Francis, D. P. & Mayet, J., 20 Nov 2019, In : BMJ (Clinical research ed.). 367, p. l6055 l6055.

    Research output: Contribution to journalArticle

  8. Prelamin A mediates myocardial inflammation in dilated and HIV-Associated cardiomyopathies

    Brayson, D., Frustaci, A., Verardo, R., Chimenti, C., Russo, M. A., Hayward, R., Ahmad, S. M., Vizcay-barrena, G., Protti, A., Zammit, P. S., Dos Remedios, C. G., Ehler, E., Shah, A. M. & Shanahan, C. M., 14 Nov 2019, In : JCI Insight. 4, 22, e126315.

    Research output: Contribution to journalArticle

  9. Standardised Framework for Quantitative Analysis of Fibrillation Dynamics

    Li, X., Roney, C. H., Handa, B. S., Chowdhury, R. A., Niederer, S. A., Peters, N. S. & Ng, F. S., 13 Nov 2019, In : Scientific Reports. 9, p. 1-10 16671.

    Research output: Contribution to journalArticle

  10. Analysis of a coupled fluid-structure interaction model of the left atrium and mitral valve

    Feng, L., Gao, H., Griffith, B., Niederer, S. & Luo, X., 1 Nov 2019, In : International Journal For Numerical Methods In Biomedical Engineering. 35, 11, e3254.

    Research output: Contribution to journalArticle

  11. Therapies to limit myocardial injury in animal models of myocarditis: a systematic review and meta-analysis

    Silverblatt, J. A., Ziff, O. J., Dancy, L., Daniel, A., Carter, B. R., Scott, P. A., Sado, D., Shah, A. M. & Bromage, D. I., Nov 2019, In : Basic Research in Cardiology. 114, 6, 48.

    Research output: Contribution to journalArticle

  12. Assessing the role of extracellular signal-regulated kinases 1 and 2 in volume overload-induced cardiac remodelling

    Jochmann, S., Elkenani, M., Mohamed, B. A., Buchholz, E., Lbik, D., Binder, L., Lorenz, K., Shah, A. M., Hasenfuß, G., Toischer, K. & Schnelle, M., 1 Oct 2019, In : ESC Heart Failure. 6, 5, p. 1015-1026 12 p.

    Research output: Contribution to journalArticle

  13. Emerging role of cardiac computed tomography in heart failure

    Aziz, W., Claridge, S., Ntalas, I., Gould, J., de Vecchi, A., Razeghi, O., Toth, D., Mountney, P., Preston, R., Rinaldi, C. A., Razavi, R., Niederer, S. & Rajani, R., 1 Oct 2019, In : ESC Heart Failure. 6, 5, p. 909-920 12 p.

    Research output: Contribution to journalReview article

  14. A rule-based method for predicting the electrical activation of the heart with cardiac resynchronization therapy from non-invasive clinical data: Medical Image Analysis

    Lee, A. W. C., Nguyen, U. C., Razeghi, O., Gould, J., Sidhu, B. S., Sieniewicz, B., Behar, J. M., Mafi-Rad, M., Plank, G., Prinzen, F. W., Rinaldi, C. A., Vernooy, K. & Niederer, S., Oct 2019, In : Medical Image Analysis. 57, p. 197-213 17 p.

    Research output: Contribution to journalArticle

  15. Myocardial Transmural Electrical Disruption Affects Electrogram Pattern

    Saha, M., Roney, C., Cochet, H., Niederer, S., Vigmond, E. & Nattel, S., Sep 2019, 2019 Computing in Cardiology, CinC 2019. IEEE Computer Society, 9005746. (Computing in Cardiology; vol. 2019-September).

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  16. Editorial: Recent Advances in Understanding the Basic Mechanisms of Atrial Fibrillation Using Novel Computational Approaches

    Zhao, J., Aslanidi, O., Kuklik, P., Lee, G., Tse, G., Niederer, S. & Vigmond, E. J., 20 Aug 2019, In : Frontiers in Physiology. 10, 1065.

    Research output: Contribution to journalEditorial

  17. Single-cell transcriptome analyses reveal novel targets modulating cardiac neovascularization by resident endothelial cells following myocardial infarction

    Li, Z., Solomonidis, E. G., Meloni, M., Taylor, R. S., Duffin, R., Dobie, R., Magalhaes, M. S., Henderson, B. E. P., Louwe, P. A., D'Amico, G., Hodivala-Dilke, K. M., Shah, A. M., Mills, N. L., Simons, B. D., Gray, G. A., Henderson, N. C., Baker, A. H. & Brittan, M., 7 Aug 2019, In : European Heart Journal. 40, 30, p. 2507-2520 14 p.

    Research output: Contribution to journalArticle

  18. The continuous heart failure spectrum: moving beyond an ejection fraction classification

    Triposkiadis, F., Butler, J., Abboud, F. M., Armstrong, P. W., Adamopoulos, S., Atherton, J. J., Backs, J., Bauersachs, J., Burkhoff, D., Bonow, R. O., Chopra, V. K., de Boer, R. A., de Windt, L., Hamdani, N., Hasenfuss, G., Heymans, S., Hulot, J. S., Konstam, M., Lee, R. T., Linke, W. A. & 22 others, Lunde, I. G., Lyon, A. R., Maack, C., Mann, D. L., Mebazaa, A., Mentz, R. J., Nihoyannopoulos, P., Papp, Z., Parissis, J., Pedrazzini, T., Rosano, G., Rouleau, J., Seferovic, P. M., Shah, A. M., Starling, R. C., Tocchetti, C. G., Trochu, J. N., Thum, T., Zannad, F., Brutsaert, D. L., Segers, V. F. & De Keulenaer, G. W., 1 Jul 2019, In : European Heart Journal. 40, 26, p. 2155-2163B 9 p.

    Research output: Contribution to journalReview article

  19. Universal atrial coordinates applied to visualisation, registration and construction of patient specific meshes

    Roney, C. H., Pashaei, A., Meo, M., Dubois, R., Boyle, P. M., Trayanova, N. A., Cochet, H., Niederer, S. A. & Vigmond, E. J., Jul 2019, In : Medical Image Analysis. 55, p. 65-75 11 p.

    Research output: Contribution to journalArticle

  20. Oxidation of PKGIα mediates an endogenous adaptation to pulmonary hypertension

    Rudyk, O., Rowan, A., Prysyazhna, O., Krasemann, S., Hartmann, K., Zhang, M., Shah, A. M., Ruppert, C., Weiss, A., Schermuly, R. T., Ida, T., Akaike, T., Zhao, L. & Eaton, P., 25 Jun 2019, In : PNAS. 116, 26, p. 13016-13025 10 p.

    Research output: Contribution to journalArticle

  21. Metabolically activated adipose tissue macrophages link obesity to triple-negative breast cancer

    Tiwari, P., Blank, A., Cui, C., Schoenfelt, K. Q., Zhou, G., Xu, Y., Khramtsova, G., Olopade, F., Shah, A. M., Khan, S. A., Rosner, M. R. & Becker, L., 3 Jun 2019, In : The Journal of experimental medicine. 216, 6, p. 1345-1358 14 p.

    Research output: Contribution to journalArticle

  22. Solution to the Unknown Boundary Tractions in Myocardial Material Parameter Estimations

    Nasopoulou, A., Nordsletten, D. A., Niederer, S. A. & Lamata, P., 30 May 2019, Functional Imaging and Modeling of the Heart - 10th International Conference, FIMH 2019, Proceedings. Ozenne, V., Vigmond, E., Coudière, Y. & Zemzemi, N. (eds.). p. 313-322 10 p. (Lecture Notes in Computer Science; vol. 11504).

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  23. Effect of Iron Isomaltoside on Skeletal Muscle Energetics in Patients with Chronic Heart Failure and Iron Deficiency: FERRIC-HF II Randomized Mechanistic Trial

    Charles-Edwards, G., Amaral, N., Sleigh, A., Ayis, S., Catibog, N., McDonagh, T., Monaghan, M., Amin-Youseff, G., Kemp, G. J., Shah, A. M. & Okonko, D. O., 21 May 2019, In : Circulation. 139, 21, p. 2386-2398 13 p.

    Research output: Contribution to journalArticle

  24. Cardioprotective Effect of the Mitochondrial Unfolded Protein Response During Chronic Pressure Overload

    Smyrnias, I., Gray, S. P., Okonko, D. O., Sawyer, G., Zoccarato, A., Catibog, N., López, B., González, A., Ravassa, S., Díez, J. & Shah, A. M., 16 Apr 2019, In : Journal of the American College of Cardiology. 73, 14, p. 1795 - 1806 12 p.

    Research output: Contribution to journalArticle

  25. Regional diastolic dysfunction in post-infarction heart failure: Role of local mechanical load and SERCA expression

    Røe, Å. T., Ruud, M., Espe, E. K., Manfra, O., Longobardi, S., Aronsen, J. M., Nordén, E. S., Husebye, T., Kolstad, T. R. S., Cataliotti, A., Christensen, G., Sejersted, O. M., Niederer, S. A., Andersen, G. Ø., Sjaastad, I. & Louch, W. E., 15 Mar 2019, In : Cardiovascular Research. 115, 4, p. 752-764 13 p.

    Research output: Contribution to journalArticle

  26. Paracrine Mechanisms of Redox Signalling for Postmitotic Cell and Tissue Regeneration

    Hervera, A., Santos, C. X., De Virgiliis, F., Shah, A. M. & Di Giovanni, S., 19 Feb 2019, In : Trends in cell biology. 29, 6, p. 514-530 17 p.

    Research output: Contribution to journalReview article

  27. Convolutional Neural Networks for Segmentation of the Left Atrium from Gadolinium-Enhancement MRI Images

    de Vente, C., Veta, M., Razeghi, O., Niederer, S., Pluim, J., Rhode, K. & Karim, R., 14 Feb 2019, Statistical Atlases and Computational Models of the Heart. Atrial Segmentation and LV Quantification Challenges - 9th International Workshop, STACOM 2018, Held in Conjunction with MICCAI 2018, Revised Selected Papers. McLeod, K., Mansi, T., Young, A., Rhode, K., Zhao, J., Li, S., Pop, M. & Sermesant, M. (eds.). Springer Verlag, p. 348-356 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11395 LNCS).

    Research output: Chapter in Book/Report/Conference proceedingConference paper

  28. Computational models in cardiology

    Niederer, S. A., Lumens, J. & Trayanova, N. A., 1 Feb 2019, In : Nature Reviews Cardiology. 16, 2, p. 100-111 12 p.

    Research output: Contribution to journalReview article

  29. A short history of the development of mathematical models of cardiac mechanics

    Niederer, S. A., Campbell, K. S. & Campbell, S. G., Feb 2019, In : Journal of Molecular and Cellular Cardiology. 127, p. 11-19 9 p., 127.

    Research output: Contribution to journalReview article

  30. A machine learning approach for the prediction of pulmonary hypertension

    Leha, A., Hellenkamp, K., Unsöld, B., Mushemi-Blake, S., Shah, A. M., Hasenfuß, G. & Seidler, T., 1 Jan 2019, In : PLoS ONE. 14, 10, e0224453.

    Research output: Contribution to journalArticle

  31. Tolerizing CTL by sustained hepatic PD-L1 expression provides a new therapy approach in mouse sepsis

    Von Knethen, A., Schäfer, A., Kuchler, L., Knape, T., Christen, U., Hintermann, E., Fißlthaler, B., Schröder, K., Brandes, R. P., Genz, B., Abshagen, K., Pützer, B. M., Sha, L. K., Weigert, A., Syed, S. N., Schulz, M., Shah, A. M., Ernst, A., Putyrski, M., Finkelmeier, F. & 7 others, Pesic, M., Greten, F., Hogardt, M., Kempf, V. A. J., Gunne, S., Parnham, M. J. & Brüne, B., 1 Jan 2019, In : Theranostics. 9, 7, p. 2003-2016 14 p.

    Research output: Contribution to journalArticle

  32. Magnetic Resonance Perfusion or Fractional Flow Reserve in Coronary Disease

    Nagel, E., Greenwood, J. P., McCann, G. P., Bettencourt, N., Shah, A. M., Hussain, S. T., Perera, D., Plein, S., Bucciarelli-Ducci, C., Paul, M., Westwood, M. A., Marber, M. & Investigators, MR-INFORM., 2019, In : New England Journal of Medicine. 380, 25, p. 2418-2428 11 p.

    Research output: Contribution to journalArticle

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