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Seeing the fetus from a DOHaD perspective: discussion paper from the advanced imaging techniques of DOHaD applications workshop held at the 2019 DOHaD World Congress

Research output: Contribution to journalReview articlepeer-review

Janna L Morrison, Oyekoya T Ayonrinde, Alison S Care, Geoffrey D Clarke, Jack R T Darby, Anna L David, Justin M Dean, Stuart B Hooper, Marcus J Kitchen, Christopher K Macgowan, Andrew Melbourne, Erin V McGillick, Charles A McKenzie, Navin Michael, Nuruddin Mohammed, Suresh Anand Sadananthan, Eric Schrauben, Timothy R H Regnault, S Sendhil Velan

Original languageEnglish
Pages (from-to)153-167
Number of pages15
JournalJournal of Developmental Origins of Health and Disease
Volume12
Issue number2
Early online date21 Sep 2020
DOIs
E-pub ahead of print21 Sep 2020
PublishedApr 2021

Bibliographical note

Funding Information: AM was supported by the Wellcome Trust (210182/Z/18/Z, 101957/Z/13/Z) and EPSRC (NS/A000027/1). Funding Information: EVM was supported by a NHMRC Peter Doherty Biomedical Early Career Fellowship (APP1138049). Funding Information: JMD is supported by the Health Research Council, New Zealand (17/076). Funding Information: JLM was funded by an ARC Future Fellowship (Level 3; FT170100431). Funding Information: CAM and TRHR are supported by the Children’s Health Research Institute and the Eunice Kennedy Shriver National Institute of Child Health and Human Development, Grant/Award Number: U01HD087181. Funding Information: ALD is supported by the National Institute for Health Research Biomedical Research Centre at the University College London Hospitals NHS Foundation Trust and the University College London. Funding Information: MJK was funded by an ARC Future Fellowship (FT160100454). Funding Information: ASC was supported by a Future Leader Fellowship (101998) from the National Heart Foundation of Australia. Publisher Copyright: © Cambridge University Press and the International Society for Developmental Origins of Health and Disease 2020.

King's Authors

Abstract

Advanced imaging techniques are enhancing research capacity focussed on the developmental origins of adult health and disease (DOHaD) hypothesis, and consequently increasing awareness of future health risks across various subareas of DOHaD research themes. Understanding how these advanced imaging techniques in animal models and human population studies can be both additively and synergistically used alongside traditional techniques in DOHaD-focussed laboratories is therefore of great interest. Global experts in advanced imaging techniques congregated at the advanced imaging workshop at the 2019 DOHaD World Congress in Melbourne, Australia. This review summarizes the presentations of new imaging modalities and novel applications to DOHaD research and discussions had by DOHaD researchers that are currently utilizing advanced imaging techniques including MRI, hyperpolarized MRI, ultrasound, and synchrotron-based techniques to aid their DOHaD research focus.

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