Seizing hope: Advancing cell therapy for pharmaco-resistant epilepsy toward the clinic

Ana Beltran Arranz; Benedikt Berninger

doi:10.1016/j.stem.2023.08.006

Seizing hope: Advancing cell therapy for pharmaco-resistant epilepsy toward the clinic

Ana Beltran Arranz, Benedikt Berninger

Developmental Neurobiology

Research output: Contribution to journal › Comment/debate

Abstract

In this issue of Cell Stem Cell, Bershteyn et al. ¹ developed a human interneuron cell therapy that reduced spontaneous seizure activity in a mouse model of mesial temporal lobe epilepsy (MTLE). The data presented here support an ongoing phase 1/2 clinical trial for the treatment of pharmaco-resistant epilepsy in patients.

Original language	English
Pages (from-to)	1287-1289
Number of pages	3
Journal	Cell Stem Cell
Volume	30
Issue number	10
DOIs	https://doi.org/10.1016/j.stem.2023.08.006
Publication status	Published - 5 Oct 2023

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title = "Seizing hope: Advancing cell therapy for pharmaco-resistant epilepsy toward the clinic",

abstract = "In this issue of Cell Stem Cell, Bershteyn et al. 1 developed a human interneuron cell therapy that reduced spontaneous seizure activity in a mouse model of mesial temporal lobe epilepsy (MTLE). The data presented here support an ongoing phase 1/2 clinical trial for the treatment of pharmaco-resistant epilepsy in patients.",

author = "{Beltran Arranz}, Ana and Benedikt Berninger",

note = "Funding Information: The authors declare no competing interests. Publisher Copyright: {\textcopyright} 2023 Elsevier Inc.",

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AU - Berninger, Benedikt

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AB - In this issue of Cell Stem Cell, Bershteyn et al. 1 developed a human interneuron cell therapy that reduced spontaneous seizure activity in a mouse model of mesial temporal lobe epilepsy (MTLE). The data presented here support an ongoing phase 1/2 clinical trial for the treatment of pharmaco-resistant epilepsy in patients.

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DO - 10.1016/j.stem.2023.08.006

M3 - Comment/debate

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JO - Cell Stem Cell

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Seizing hope: Advancing cell therapy for pharmaco-resistant epilepsy toward the clinic

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