Selecting synaptic partners: GRASPing the role of UNC-6/netrin

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Forming synaptic connections of the appropriate strength between specific neurons is crucial for constructing neural circuits to control behavior. A recent paper in Neural Development describes the use of a synapse-specific label in Caenorhabditis elegans to implicate local UNC-6/netrin signaling in this developmental process. Thus, as well as their well known roles in cell migration and axon guidance, UNC-6/netrin signals distinguish an appropriate synaptic partner from other potential targets.

Original languageEnglish
Article number43
Pages (from-to)-
Number of pages3
JournalBMC Biology
Early online date10 Jun 2011
Publication statusPublished - 2011


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