Selecting synaptic partners: GRASPing the role of UNC-6/netrin

TY - JOUR

T1 - Selecting synaptic partners: GRASPing the role of UNC-6/netrin

AU - Ch'ng, QueeLim

PY - 2011

Y1 - 2011

N2 - Forming synaptic connections of the appropriate strength between specific neurons is crucial for constructing neural circuits to control behavior. A recent paper in Neural Development describes the use of a synapse-specific label in Caenorhabditis elegans to implicate local UNC-6/netrin signaling in this developmental process. Thus, as well as their well known roles in cell migration and axon guidance, UNC-6/netrin signals distinguish an appropriate synaptic partner from other potential targets.

AB - Forming synaptic connections of the appropriate strength between specific neurons is crucial for constructing neural circuits to control behavior. A recent paper in Neural Development describes the use of a synapse-specific label in Caenorhabditis elegans to implicate local UNC-6/netrin signaling in this developmental process. Thus, as well as their well known roles in cell migration and axon guidance, UNC-6/netrin signals distinguish an appropriate synaptic partner from other potential targets.

U2 - 10.1186/1741-7007-9-43

DO - 10.1186/1741-7007-9-43

M3 - Editorial

SN - 1741-7007

VL - 9

SP - -

JO - BMC Biology

JF - BMC Biology

M1 - 43

ER -