Self-reported COVID-19 vaccine hesitancy and uptake among participants from different racial and ethnic groups in the United States and United Kingdom

COPE Consortium

doi:10.1038/s41467-022-28200-3

Self-reported COVID-19 vaccine hesitancy and uptake among participants from different racial and ethnic groups in the United States and United Kingdom

COPE Consortium

Research output: Contribution to journal › Article › peer-review

135 Citations (Scopus)

Abstract

Worldwide, racial and ethnic minorities have been disproportionately impacted by COVID-19 with increased risk of infection, its related complications, and death. In the initial phase of population-based vaccination in the United States (U.S.) and United Kingdom (U.K.), vaccine hesitancy may result in differences in uptake. We performed a cohort study among U.S. and U.K. participants who volunteered to take part in the smartphone-based COVID Symptom Study (March 2020-February 2021) and used logistic regression to estimate odds ratios of vaccine hesitancy and uptake. In the U.S. (n = 87,388), compared to white participants, vaccine hesitancy was greater for Black and Hispanic participants and those reporting more than one or other race. In the U.K. (n = 1,254,294), racial and ethnic minority participants showed similar levels of vaccine hesitancy to the U.S. However, associations between participant race and ethnicity and levels of vaccine uptake were observed to be different in the U.S. and the U.K. studies. Among U.S. participants, vaccine uptake was significantly lower among Black participants, which persisted among participants that self-reported being vaccine-willing. In contrast, statistically significant racial and ethnic disparities in vaccine uptake were not observed in the U.K sample. In this study of self-reported vaccine hesitancy and uptake, lower levels of vaccine uptake in Black participants in the U.S. during the initial vaccine rollout may be attributable to both hesitancy and disparities in access.

Original language	English
Article number	636
Pages (from-to)	636
Number of pages	1
Journal	Nature Communications
Volume	13
Issue number	1
Early online date	1 Feb 2022
DOIs	https://doi.org/10.1038/s41467-022-28200-3
Publication status	Published - Dec 2022

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1038/s41467-022-28200-3

Cite this

@article{75f5c832779e436398e2f6ed68a02a9e,

title = "Self-reported COVID-19 vaccine hesitancy and uptake among participants from different racial and ethnic groups in the United States and United Kingdom",

abstract = "Worldwide, racial and ethnic minorities have been disproportionately impacted by COVID-19 with increased risk of infection, its related complications, and death. In the initial phase of population-based vaccination in the United States (U.S.) and United Kingdom (U.K.), vaccine hesitancy may result in differences in uptake. We performed a cohort study among U.S. and U.K. participants who volunteered to take part in the smartphone-based COVID Symptom Study (March 2020-February 2021) and used logistic regression to estimate odds ratios of vaccine hesitancy and uptake. In the U.S. (n = 87,388), compared to white participants, vaccine hesitancy was greater for Black and Hispanic participants and those reporting more than one or other race. In the U.K. (n = 1,254,294), racial and ethnic minority participants showed similar levels of vaccine hesitancy to the U.S. However, associations between participant race and ethnicity and levels of vaccine uptake were observed to be different in the U.S. and the U.K. studies. Among U.S. participants, vaccine uptake was significantly lower among Black participants, which persisted among participants that self-reported being vaccine-willing. In contrast, statistically significant racial and ethnic disparities in vaccine uptake were not observed in the U.K sample. In this study of self-reported vaccine hesitancy and uptake, lower levels of vaccine uptake in Black participants in the U.S. during the initial vaccine rollout may be attributable to both hesitancy and disparities in access.",

author = "{COPE Consortium} and Nguyen, {Long H.} and Joshi, {Amit D.} and Drew, {David A.} and Jordi Merino and Wenjie Ma and Lo, {Chun Han} and Sohee Kwon and Kai Wang and Graham, {Mark S.} and Lorenzo Polidori and Cristina Menni and Sudre, {Carole H.} and Adjoa Anyane-Yeboa and Astley, {Christina M.} and Warner, {Erica T.} and Hu, {Christina Y.} and Somesh Selvachandran and Richard Davies and Denis Nash and Franks, {Paul W.} and Jonathan Wolf and Sebastien Ourselin and Steves, {Claire J.} and Spector, {Tim D.} and Chan, {Andrew T.}",

note = "Funding Information: Zoe provided in kind support for all aspects of building, running, and supporting the app and service to users worldwide. L.H.N. is supported by the NIH/NIDDK NIH K23DK125838, American Gastroenterological Association Research Scholars Award, and Crohn{\textquoteright}s and Colitis Foundation Career Development Award and Research Fellowship Award. D.A.D. is supported by the NIH/NIDDK K01DK120742. L.H.N. and D.A.D. are supported by the American Gastroenterological Association-Takeda COVID-19 Rapid Response Research Award (AGA2021-5102). The Massachusetts Consortium on Pathogen Readiness (MassCPR) and Mark and Lisa Schwartz supported MGH investigators. C.M. is supported by the Chronic Disease Research Foundation. C.M. and T.D.S. are supported by the Medical Research Council AimHy Project Grant (MR/M016560/1). A.T.C. is the Stuart and Suzanne Steele MGH Research Scholar and Stand Up to Cancer scientist. Publisher Copyright: {\textcopyright} 2022, The Author(s).",

year = "2022",

month = dec,

doi = "10.1038/s41467-022-28200-3",

language = "English",

volume = "13",

pages = "636",

journal = "Nature Communications",

issn = "2041-1723",

publisher = "Nature Publishing Group",

number = "1",

}

TY - JOUR

T1 - Self-reported COVID-19 vaccine hesitancy and uptake among participants from different racial and ethnic groups in the United States and United Kingdom

AU - COPE Consortium

AU - Nguyen, Long H.

AU - Joshi, Amit D.

AU - Drew, David A.

AU - Merino, Jordi

AU - Ma, Wenjie

AU - Lo, Chun Han

AU - Kwon, Sohee

AU - Wang, Kai

AU - Graham, Mark S.

AU - Polidori, Lorenzo

AU - Menni, Cristina

AU - Sudre, Carole H.

AU - Anyane-Yeboa, Adjoa

AU - Astley, Christina M.

AU - Warner, Erica T.

AU - Hu, Christina Y.

AU - Selvachandran, Somesh

AU - Davies, Richard

AU - Nash, Denis

AU - Franks, Paul W.

AU - Wolf, Jonathan

AU - Ourselin, Sebastien

AU - Steves, Claire J.

AU - Spector, Tim D.

AU - Chan, Andrew T.

N1 - Funding Information: Zoe provided in kind support for all aspects of building, running, and supporting the app and service to users worldwide. L.H.N. is supported by the NIH/NIDDK NIH K23DK125838, American Gastroenterological Association Research Scholars Award, and Crohn’s and Colitis Foundation Career Development Award and Research Fellowship Award. D.A.D. is supported by the NIH/NIDDK K01DK120742. L.H.N. and D.A.D. are supported by the American Gastroenterological Association-Takeda COVID-19 Rapid Response Research Award (AGA2021-5102). The Massachusetts Consortium on Pathogen Readiness (MassCPR) and Mark and Lisa Schwartz supported MGH investigators. C.M. is supported by the Chronic Disease Research Foundation. C.M. and T.D.S. are supported by the Medical Research Council AimHy Project Grant (MR/M016560/1). A.T.C. is the Stuart and Suzanne Steele MGH Research Scholar and Stand Up to Cancer scientist. Publisher Copyright: © 2022, The Author(s).

PY - 2022/12

Y1 - 2022/12

N2 - Worldwide, racial and ethnic minorities have been disproportionately impacted by COVID-19 with increased risk of infection, its related complications, and death. In the initial phase of population-based vaccination in the United States (U.S.) and United Kingdom (U.K.), vaccine hesitancy may result in differences in uptake. We performed a cohort study among U.S. and U.K. participants who volunteered to take part in the smartphone-based COVID Symptom Study (March 2020-February 2021) and used logistic regression to estimate odds ratios of vaccine hesitancy and uptake. In the U.S. (n = 87,388), compared to white participants, vaccine hesitancy was greater for Black and Hispanic participants and those reporting more than one or other race. In the U.K. (n = 1,254,294), racial and ethnic minority participants showed similar levels of vaccine hesitancy to the U.S. However, associations between participant race and ethnicity and levels of vaccine uptake were observed to be different in the U.S. and the U.K. studies. Among U.S. participants, vaccine uptake was significantly lower among Black participants, which persisted among participants that self-reported being vaccine-willing. In contrast, statistically significant racial and ethnic disparities in vaccine uptake were not observed in the U.K sample. In this study of self-reported vaccine hesitancy and uptake, lower levels of vaccine uptake in Black participants in the U.S. during the initial vaccine rollout may be attributable to both hesitancy and disparities in access.

AB - Worldwide, racial and ethnic minorities have been disproportionately impacted by COVID-19 with increased risk of infection, its related complications, and death. In the initial phase of population-based vaccination in the United States (U.S.) and United Kingdom (U.K.), vaccine hesitancy may result in differences in uptake. We performed a cohort study among U.S. and U.K. participants who volunteered to take part in the smartphone-based COVID Symptom Study (March 2020-February 2021) and used logistic regression to estimate odds ratios of vaccine hesitancy and uptake. In the U.S. (n = 87,388), compared to white participants, vaccine hesitancy was greater for Black and Hispanic participants and those reporting more than one or other race. In the U.K. (n = 1,254,294), racial and ethnic minority participants showed similar levels of vaccine hesitancy to the U.S. However, associations between participant race and ethnicity and levels of vaccine uptake were observed to be different in the U.S. and the U.K. studies. Among U.S. participants, vaccine uptake was significantly lower among Black participants, which persisted among participants that self-reported being vaccine-willing. In contrast, statistically significant racial and ethnic disparities in vaccine uptake were not observed in the U.K sample. In this study of self-reported vaccine hesitancy and uptake, lower levels of vaccine uptake in Black participants in the U.S. during the initial vaccine rollout may be attributable to both hesitancy and disparities in access.

UR - http://www.scopus.com/inward/record.url?scp=85124058662&partnerID=8YFLogxK

U2 - 10.1038/s41467-022-28200-3

DO - 10.1038/s41467-022-28200-3

M3 - Article

C2 - 35105869

AN - SCOPUS:85124058662

SN - 2041-1723

VL - 13

SP - 636

JO - Nature Communications

JF - Nature Communications

IS - 1

M1 - 636

ER -

Self-reported COVID-19 vaccine hesitancy and uptake among participants from different racial and ethnic groups in the United States and United Kingdom

Abstract

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this