Sensing wounds by spilling cellular guts: Damage-associated protease release can initiate tissue repair

Maria Del Carmen Diaz-de-la-Loza, Yutaka Matsubayashi, Brian Marc Stramer

Research output: Contribution to journalComment/debatepeer-review

Abstract

Epithelia have an innate yet mysterious capacity to rapidly sense and respond to tissue damage. In this issue of Developmental Cell, O'Connor et al. exploit the genetics of Drosophila to reveal that protease release as a result of tissue injury activates insect cytokines to initiate immediate epithelial repair responses.

Original languageEnglish
Pages (from-to)2137-2139
Number of pages3
JournalDevelopmental Cell
Volume56
Issue number15
DOIs
Publication statusPublished - 9 Aug 2021

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